Cited by 567Drug Solubulity and Delivery SystemsSurfactants and Colloidal SystemsProteins in Food Systems

Nanoemulsion components screening and selection: A technical note

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Azeem, Adnan, Rizwan, Mohammad, Ahmad, Farhan J., Iqbal, Zeenat, Khar, Roop K., Aqil, M., Talegaonkar, Sushama·2009·AAPS PharmSciTech

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  • Common emulsifiers for nanoemulsions include lecithin, sodium deoxycholate, Tween 20/40/60/80, Span 20/40/60/80, poloxamers, sodium dodecyl sulfate, casein, polysaccharides and PEG-containing block copolymers.

    “Lecithin (phosphatidylcholine) [36], sodium deoxycholate (bile salt) [37], polyoxyethlene sorbitan monolaurate (Tween 20, 40, 60, 80) [38] and sorbitan monolaurate (Span 20, 40, 60, 80) [39] are commonly employed in the preparation of NEs. Other surfactants proposed are poloxamers [40], sodium dodecyl sulfate [41], amphiphilic proteins like casein [42], polysaccharides (starch derivatives, gums) [”

    From Nanoemulsions for “Nose-to-Brain” Drug Delivery (2019) · cites this paper as [38]

    The Screening of Surfactants and Components sections identify Tween 20, 60, and 80 as surfactants screened for nanoemulsion formulation. The citation is attached to the Tween list, but our copy does not identify Tween 40, so it does not support the full list attributed to this source. No page numbers are available in our copy. (LLM, conf=0.88)

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Authors
Azeem, A., Rizwan, M., Ahmad, F. J., Iqbal, Z., Khar, R. K., Aqil, M., & Talegaonkar, S.
Affiliations
Jamia Hamdard (IN)
Corresponding author
Azeem, Adnan
Venue
AAPS PharmSciTech
Published
2009-01-16
Volume
10
Issue
1
Pages
69-76
ISSN
1530-9932 (ISSN-L)
OpenAlex
W2154862932
Cited by
567
References
41
Citations by year
2026: 44 · 2025: 58 · 2024: 56 · 2023: 53 · 2022: 54 · 2021: 55 · 2020: 52 · 2019: 45 · 2018: 35 · 2017: 21 · 2016: 30 · 2015: 18 · 2014: 14 · 2013: 12 · 2012: 6
FWCI
4.34
Type
journal article
Language
en
Open access
Locations
  • AAPS PharmSciTech (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
University Grants Commission
Topics
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Drug Solubulity and Delivery Systems
  • Physical Sciences › Chemistry › Organic Chemistry › Surfactants and Colloidal Systems
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
Keywords
nanoemulsions, surfactant selection, cosurfactants, oil selection, formulation screening, ropinirole, lipophilic drugs, surfactant to cosurfactant ratio, spontaneous emulsification, drug delivery systems, surfactant toxicity
MeSH terms
Chemistry, Pharmaceutical, Drug Compounding, Drug Stability, Emulsions, Hydrogen-Ion Concentration, Indoles, Oils, Surface Properties, Surface-Active Agents, Technology, Pharmaceutical, Temperature, Viscosity, Water, Nanotechnology, Nanoparticles

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