The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Origin of Mammalian Gonadotropin-Releasing Hormones
Abstract
GONADOTROPIN-releasing hormone (GnRH) plays a pivotal role in reproduction. The existence of this neuropeptide, also called LHRH, was predicted in the 1950s (1), but the structure of the 10 amino acid peptide for porcine and ovine brains was not reported until the 1970s (2, 3). In the 20 yr since then, only one form of GnRH has been identified in most placental mammals, and this is still considered to be the sole neuropeptide causing the release of LH and FSH. The structure and functions of the mammalian form of GnRH have been reviewed a number of times (4s–8). Meanwhile, both mammalian GnRH and related forms of GnRH are now known to be present in primitive placental mammals, nonplacental mammals, and other vertebrates. Novel functions, in addition to the release of gonadotropins, exist. Studies of GnRH peptides and their genes have altered our views on the origin, function, and regulation of this neuropeptide.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Origin of luteinizing hormone-releasing hormone neurons
Schwanzel-Fukuda, M., & Pfaff, D. W. (1989) · Nature · doi:10.1038/338161a0 · Cited by 1,116
Cited by
A novel mammalian receptor for the evolutionarily conserved type II GnRH
Millar, R., Lowe, S., Conklin, D., Pawson, A., Maudsley, S., Troskie, B., Ott, T., Millar, M., Lincoln, G., Sellar, R., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.141048498 · Cited by 314
Jimenez-Liñan, M., Rubin, B. S., & King, J. C. (1997) · Endocrinology · doi:10.1210/endo.138.10.5454 · Cited by 140
Matsuda, K., Nakamura, K., Shimakura, S.-I., Miura, T., Kageyama, H., Uchiyama, M., Shioda, S., & Ando, H. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2008.01.011 · Cited by 96
Gonadotropin-releasing hormone 2 suppresses food intake in the zebrafish, Danio rerio
Nishiguchi, R., Azuma, M., Yokobori, E., Uchiyama, M., & Matsuda, K. (2012) · Frontiers in Endocrinology · doi:10.3389/fendo.2012.00122 · Cited by 71
Kang, K. S., Shimizu, K., Azuma, M., Ui, Y., Nakamura, K., Uchiyama, M., & Matsuda, K. (2011) · Peptides · doi:10.1016/j.peptides.2010.10.013 · Cited by 31
Metadata
- Authors
- SHERWOOD, N. M., LOVEJOY, D. A., & COE, I. R.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 1993-04
- Volume
- 14
- Issue
- 2
- Pages
- 241-254
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2139981662
- Cited by
- 269
- References
- 1
- FWCI
- 19.66
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Origin of Mammalian Gonadotropin-Releasing Hormones. https://app.cochat.ai/papers/10.1210/edrv-14-2-241
- The paper
- SHERWOOD, N. M., LOVEJOY, D. A., & COE, I. R. (1993). Origin of Mammalian Gonadotropin-Releasing Hormones. Endocrine Reviews. https://doi.org/10.1210/edrv-14-2-241
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
