The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Gonadotropin-Releasing Hormone Receptors: Characterization, Physiological Regulation, and Relationship to Reproductive Function
Abstract
THE TONIC and cyclic secretion of gonadotropins is mediated by the hypothalamic production of gonadotropin releasing hormone (GnRH). The direct assessment of hypothalamic function has been hampered by the absence of reliable methods for the measurement of GnRH production and secretion. Endogenous hypothalamic GnRH probably never reaches the general circulation in sufficiently high concentration to be measured by RIA (1–5), since the pituitary gland has the capacity to metabolize the majority of the peptide secreted into the hypothalamo-hypophyseal portal circulation (6–10). Attempts to determine the rate and amplitude of GnRH secretion have shown that GnRH concentrations in hypophyseal stalk plasma fluctuate between 20 and 800 pM (11–14). Such studies have revealed that GnRH is released in a pulsatile fashion, although rapid changes in secretion rate cannot be detected during the long period required for sample collection. In addition to modulating the concentration of GnRH in hypophyseal portal plasma (14–16), the sex-steroid milieu of the animal may also regulate the frequency of GnRH pulses.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Belchetz, P. E., Plant, T. M., Nakai, Y., Keogh, E. J., & Knobil, E. (1978) · Science · doi:10.1126/science.100883 · Cited by 1,385
Muscarinic Cholinergic Binding in Rat Brain
Yamamura, H. I., & Snyder, S. H. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.5.1725 · Cited by 1,203
Calmodulin—an intracellular calcium receptor
Means, A. R., & Dedman, J. R. (1980) · Nature · doi:10.1038/285073a0 · Cited by 969
Gonadotropin-releasing hormone surge in pro-oestrous rats
SARKAR, D. K., CHIAPPA, S. A., FINK, G., & SHERWOOD, N. M. (1976) · Nature · doi:10.1038/264461a0 · Cited by 502
CARMEL, P. W., ARAKI, S., & FERIN, M. (1976) · Endocrinology · doi:10.1210/endo-99-1-243 · Cited by 482
Gonadotropin-releasing hormone analogue binds to luteal cells and inhibits progesterone production
Clayton, R. N., Harwood, J. P., & Catt, K. J. (1979) · Nature · doi:10.1038/282090a0 · Cited by 339
Self-citationNAKAI, Y., PLANT, T. M., HESS, D. L., KEOGH, E. J., & KNOBIL, E. (1978) · Endocrinology · doi:10.1210/endo-102-4-1008 · Cited by 279
Pituitary Gonadotropin-Releasing Hormone Receptors During the Rat Estrous Cycle
Savoy‐Moore, R. T., Schwartz, N. B., Duncan, J. A., & Marshall, J. C. (1980) · Science · doi:10.1126/science.6250218 · Cited by 250
Regulation of Pituitary Receptors for Gonadotropin-Releasing Hormone during the Rat Estrous Cycle
Clayton, R. N., Solano, A. R., GARCIA-VELA, A., Dufau, M. L., & Catt, K. J. (1980) · Endocrinology · doi:10.1210/endo-107-3-699 · Cited by 249
Self-citationAIYER, M. S., CHIAPPA, S. A., & Fink, G. (1974) · Journal of Endocrinology · doi:10.1677/joe.0.0620573 · Cited by 234
Cited by
Neuroendocrine Control of the Ovarian Cycle of the Rat
Levine, J. E. (2015) · Knobil and Neill's Physiology of Reproduction · doi:10.1016/b978-0-12-397175-3.00026-0 · Cited by 140
Effects of Chronic Ethanol Diet on Pituitary-Testicular Function of the Rat1
Salonen, I., & Huhtaniemi, I. (1990) · Biology of Reproduction · doi:10.1095/biolreprod42.1.55 · Cited by 84
Ultrashort Feedback Control of Luteinizing Hormone-Releasing Hormone Secretion in Vitro*
ZANISI, M., MESSI, E., MOTTA, M., & MARTINI, L. (1987) · Endocrinology · doi:10.1210/endo-121-6-2199 · Cited by 48
Metadata
- Authors
- CLAYTON, R. N., & CATT, K. J.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 1981-04
- Volume
- 2
- Issue
- 2
- Pages
- 186-209
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2016065996
- Cited by
- 522
- References
- 38
- FWCI
- 34.65
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Gonadotropin-Releasing Hormone Receptors: Characterization, Physiological Regulation, and Relationship to Reproductive Function. https://app.cochat.ai/papers/10.1210/edrv-2-2-186
- The paper
- CLAYTON, R. N., & CATT, K. J. (1981). Gonadotropin-Releasing Hormone Receptors: Characterization, Physiological Regulation, and Relationship to Reproductive Function. Endocrine Reviews. https://doi.org/10.1210/edrv-2-2-186
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
