CoChat
Sign Up
Cited by 82

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The Follicle-Stimulating Hormone Receptor: Biochemistry, Molecular Biology, Physiology, and Pathophysiology

Simoni, Manuela, Gromoll, Jörg, Nieschlag, Eberhard·1997·Endocrine Reviews
DOI 10.1210/edrv.18.6.0320
Open this paper in CoChat — free account

Abstract

FSH IS the central hormone of mammalian reproduction, necessary for gonadal development and maturation at puberty and for gamete production during the fertile phase of life (1, 2). Together with LH, this gonadotropin is produced and secreted by the pituitary gland as a highly heterogeneous glycoprotein (3, 4). FSH acts by binding to specific receptors, localized exclusively in the gonads. The FSH receptor belongs to the family of G protein-coupled receptors, complex transmembrane proteins characterized by seven hydrophobic helices inserted in the plasmalemma and by intracellular and extracellular domains of variable dimensions depending on the type of ligand (5). The intracellular portion of the FSH receptor is coupled to a Gs protein and, upon receptor activation by the hormonal interaction with the extracellular domain, initiates the cascade of events that ultimately leads to the specific biological effects of the gonadotropin. After two decades of investigations using classic biochemical approaches, the FSH receptor cDNA was finally cloned in 1990, the last in the group of closely related receptors for the glycoprotein hormones (6). Thereafter the first mutations were described, with impressive impact on the reproductive phenotype (7, 8). The new knowledge emerging from naturally occurring mutations and from in vitro molecular work provides important new insights into FSH physiology and pathophysiology. Unlike the cognate LH and TSH receptor, the functional properties of w…

Overview

Integrity signals

Registry

Crossref · 10.1210/edrv.18.6.0320

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Human ovarian granulosa cells, endometrium, myometrium, cervix and testis Sertoli cells all express FSHR.

    “Human ovarian granulosa cells [13], endometrium [47], myometrium [19], cervix [19] and testis Sertoli cells [13] all express FSHR.”

    From Hsa-mir-548 family expression in human reproductive tissues (2021) · cites this paper as [13]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 391

  1. Simoni, 1995, FSH in therapy: physiological basis, new preparations and clinical use., Reprod Med Rev, 4, 163, 10.1017/S0962279900001150 · DOI
  2. Chappel, 1991, Reevaluation of the roles of luteinizing hormone and follicle-stimulating hormone in the ovulatory process., Hum Reprod, 6, 1206, 10.1093/oxfordjournals.humrep.a137513 · DOI
  3. Moyle, 1995, Gonadotropins, In: De Groot LJ (ed) Endocrinology. WB Saunders Company, Philadelphia, pp, 230
  4. Ulloa-Aguirre, 1995, Follicle-stimulating isohormones: characterization and physiological relevance., Endocr Rev, 16, 765, 10.1210/edrv-16-6-765 · DOI
  5. Gudermann, 1995, Receptors and G proteins as primary components of transmembrane signal transduction. I. G-protein-coupled receptors: structure and function., J Mol Med, 73, 51, 10.1007/BF00270578 · DOI
  6. Sprengel, 1990, The testicular receptor for follicle-stimulating hormone: structure and functional expression of cloned cDNA., Mol Endocrinol, 4, 525, 10.1210/mend-4-4-525 · DOI
  7. Aittomäki, 1995, Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure., Cell, 82, 959, 10.1016/0092-8674(95)90275-9 · DOI
  8. Gromoll, 1996, An activating mutation of the follicle-stimulating hormone receptor autonomously sustains spermatogenesis in a hypophysectomized man., J Clin Endocrinol Metab, 81, 1367
  9. Segaloff, 1993, The lutropin/choriogonadotropin receptor … 4 years later., Endocr Rev, 3, 324
  10. Kosugi, 1995, TSH and LH receptor., Endocr J, 42, 587, 10.1507/endocrj.42.587 · DOI
  11. Kohn, 1994, The thyrotropin receptor., Vitam Horm, 50, 287, 10.1016/S0083-6729(08)60658-5 · DOI
  12. Tonacchera, 1996, TSH receptor and disease., Clin Endocrinol (Oxf), 44, 621, 10.1046/j.1365-2265.1996.746567.x · DOI
  13. Misrahi, 1993, Molecular and cellular biology of gonadotropin receptors, In: Adashi EY, Leung PCK (eds) The Ovary. Raven Press, New York, pp, 57
  14. Means, 1972, Peptide hormone“ receptors”: specific binding of 3H-FSH to testis., Endocrinology, 90, 39, 10.1210/endo-90-1-39 · DOI
  15. Vaitukaitis, 1971, A method for the preparation of radioactive FSH with preservation of biological activity., Endocrinology, 89, 1356, 10.1210/endo-89-6-1356 · DOI
  16. Bhalla, 1974, Properties of follicle-stimulating hormone-receptor interactions. Specific binding of human follicle-stimulating hormone to rat testes., J Biol Chem, 249, 43, 10.1016/S0021-9258(19)43088-3 · DOI
  17. Abou-Issa, 1976, Properties of follitropin-receptor interaction., J Biol Chem, 251, 3326, 10.1016/S0021-9258(17)33441-5 · DOI
  18. Dufau, 1977, Soluble FSH receptors from the rat testis., FEBS Lett, 81, 359, 10.1016/0014-5793(77)80554-1 · DOI
  19. Orth, 1977, Localization of 125I-labeled FSH in the testes of hypophysectomized rats by autoradiography at the light and electron microscope levels., Endocrinology, 101, 262, 10.1210/endo-101-1-262 · DOI
  20. Wahlström, 1983, Localization of luteinizing hormone, follicle-stimulating hormone, prolactin and their receptors in human and rat testis using immunohistochemistry and radioreceptor assay., J Clin Endocrinol Metab, 57, 825, 10.1210/jcem-57-4-825 · DOI
  21. Cheng, 1975, Properties of follicle-stimulating hormone receptor in cell membranes of bovine testis., Biochem J, 149, 123, 10.1042/bj1490123 · DOI
  22. Abou-Issa, 1977, Solubilization and some characteristics of the follitropin receptor from calf testis., J Biol Chem, 252, 4166, 10.1016/S0021-9258(17)40247-X · DOI
  23. Smith, 1985, The subunit structure of the follitropin (FSH) receptor. Photoaffinity labeling of the membrane-bound receptor follitropin complex in situ., J Biol Chem, 260, 14297, 10.1016/S0021-9258(17)38717-3 · DOI
  24. Smith, 1986, Quaternary structure of the calf testis follitropin receptor., J Biol Chem, 261, 9850, 10.1016/S0021-9258(18)67593-3 · DOI
  25. Dattatreyamurty, 1987, Physical and functional association of follitropin receptors with cholera toxin-sensitive guanine nucleotide-binding protein., J Biol Chem, 262, 11737, 10.1016/S0021-9258(18)60873-7 · DOI
  26. Grasso, 1988, Reconstitution of hormone-responsive detergent-solubilized follicle-stimulating hormone receptors into liposomes., Mol Endocrinol, 2, 420, 10.1210/mend-2-5-420 · DOI
  27. Dattatreyamurty, 1986, Solubilization of functional and stable follitropin receptors from light membranes of bovine calf testis., J Biol Chem, 261, 13104, 10.1016/S0021-9258(18)69277-4 · DOI
  28. Dattatreyamurty, 1990, Purification of follitropin receptor from bovine calf testes., J Biol Chem, 265, 5494, 10.1016/S0021-9258(19)39389-5 · DOI
  29. Maghuin-Rogister, 1978, Study of follitropin receptors in testis using a homologous system. Binding of porcine follitropin to plasma membranes from immature porcine testis and correlation with adenylate cyclase stimulation., Eur J Biochem, 86, 121, 10.1111/j.1432-1033.1978.tb12291.x · DOI
  30. Berman, 1982, Studies on primate gonadotropin receptors: characterization of the rhesus monkey testicular follicle-stimulating hormone receptors., J Clin Endocrinol Metab, 55, 1153, 10.1210/jcem-55-6-1153 · DOI
  31. Berman, 1982, Characterization of primate testicular FSH receptors., Ann NY Acad Sci, 383, 426, 10.1111/j.1749-6632.1982.tb23182.x · DOI
  32. Berman, 1984, Identification of specific FSH binding sites in the testes of adult monkeys of different species., J Reprod Fertil, 70, 463, 10.1530/jrf.0.0700463 · DOI
  33. Yoon, 1987, Immunocytochemical localization of hFSH as an index of Sertoli cell function in the human testis., Acta Endocrinol (Copenh), 116, 333, 10.1530/acta.0.1160333 · DOI
  34. Hovatta, 1986, Testicular gonadotrophins and their receptors in human cryptorchidism as revealed by immunohistochemistry and radioreceptor assay., Acta Endocrinol (Copenh), 111, 128, 10.1530/acta.0.1110128 · DOI
  35. Namiki, 1984, Abnormality of testicular FSH receptors in infertile men., Acta Endocrinol (Copenh), 106, 548, 10.1530/acta.0.1060548 · DOI
  36. Namiki, 1986, Testicular follicle-stimulating hormone receptors and effectiveness of human menopausal gonadotrophin treatment in infertile men., Clin Endocrinol (Oxf), 25, 495, 10.1111/j.1365-2265.1986.tb03601.x · DOI
  37. Dias, 1981, Effect of the structure-stabilizing agent glycerol on detergent-solubilized follicle-stimulating hormone receptors from calf testis., Endocrinology, 109, 736, 10.1210/endo-109-3-736 · DOI
  38. Ketelslegers, 1978, Follitropin receptors in rat testis. Characterization with enzymatically 125I-labeled human follitropin., Biochim Biophys Acta, 541, 360, 10.1016/0304-4165(78)90195-2 · DOI
  39. Yoon, 1990, Available FSH receptors in adult rat testis in vivo., J Endocrinol, 125, 293, 10.1677/joe.0.1250293 · DOI
  40. Cheng, 1975, A radioreceptor assay for follicle-stimulating hormone., J Clin Endocrinol Metab, 41, 581, 10.1210/jcem-41-3-581 · DOI
  41. Ketelslegers, 1978, Developmental changes in testicular gonadotropin receptors: plasma gonadotropins and plasma testosterone in the rat., Endocrinology, 103, 212, 10.1210/endo-103-1-212 · DOI
  42. Orth, 1978, Autoradiographic localization of specifically bound 125I-labeled follicle-stimulating hormone on spermatogonia of rat testis., Endocrinology, 103, 1944, 10.1210/endo-103-5-1944 · DOI
  43. Böckers, 1994, Localization of follicle-stimulating hormone immunoreactivity and hormone receptor mRNA in testicular tissue of infertile men., Cell Tissue Res, 278, 595, 10.1007/BF00331379 · DOI
  44. Vannier, 1996, Anti-human FSH receptor monoclonal antibodies: immunochemical and immunocytochemical characterization of the receptor., Biochemistry, 35, 1358, 10.1021/bi952290f · DOI
  45. Yee, 1983, Testicular macrophages: isolation, characterization and hormonal responsiveness., Biol Reprod, 29, 1319, 10.1095/biolreprod29.5.1319 · DOI
  46. Yee, 1985, Biochemical consequences of follicle-stimulating hormone binding to testicular macrophages in culture., Biol Reprod, 32, 872, 10.1095/biolreprod32.4.872 · DOI
  47. Yee, 1985, In vivo effects of follicle-stimulating hormone on testicular macrophages., Biol Reprod, 32, 880, 10.1095/biolreprod32.4.880 · DOI
  48. Ghinea, 1994, How protein hormones reach their target cells. Receptor-mediated transcytosis of hCG through endothelial cells., J Cell Biol, 125, 87, 10.1083/jcb.125.1.87 · DOI
  49. Ghinea, 1992, Pathways of internalization of the hCG/LH receptor: immunoelectron microscopic studies in Leydig cells and transfected L-cells., J Cell Biol, 118, 1347, 10.1083/jcb.118.6.1347 · DOI
  50. Misrahi, 1996, The LH/CG and FSH receptors: different molecular forms and intracellular traffic., Mol Cell Endocrinol, 125, 161, 10.1016/S0303-7207(96)03953-6 · DOI
  51. O’Neill, 1984, Evidence for the role of phospholipids in follicle-stimulating hormone binding to membrane-bound and soluble receptors from calf testis., Endocrinology, 114, 1135, 10.1210/endo-114-4-1135 · DOI
  52. Casey, 1995, Protein lipidation in cell signaling., Science, 268, 221, 10.1126/science.7716512 · DOI
  53. Zhu, 1995, The lutropin/choriogonadotropin receptor is palmitoylated at intracellular cysteine residues., Mol Endocrinol, 9, 141
  54. Shin, 1986, Structural homologies in the lutropin/human choriogonadotropin receptor and the follitropin receptor on porcine granulosa cells., Biochemistry, 25, 3410, 10.1021/bi00359a047 · DOI
  55. Dias, 1982, Characterization of a follitropin (FSH) binding component prepared from immature bovine testes in the absence of detergent., J Biol Chem, 257, 613, 10.1016/S0021-9258(19)68237-2 · DOI
  56. Reichert Jr, 1989, The follicle-stimulating hormone (FSH) receptor in testis: interaction with FSH, mechanism of signal transduction and properties of the purified receptor., Biol Reprod, 40, 13, 10.1095/biolreprod40.1.13 · DOI
  57. Dattatreyamurty, 1992, The size of the mature membrane receptor for follicle-stimulating hormone is larger than predicted from its cDNA., J Mol Endocrinol, 9, 115, 10.1677/jme.0.0090115 · DOI
  58. Means, 1980, Regulation of the testis Sertoli cell by follicle-stimulating hormone., Annu Rev Physiol, 42, 59, 10.1146/annurev.ph.42.030180.000423 · DOI
  59. Catt, 1979, Luteinizing hormone-releasing hormone induced regulation of gonadotropin and prolactin receptors in the rat testis., Endocrinology, 104, 17, 10.1210/endo-104-1-17 · DOI
  60. O’Shaughnessy, 1978, Reduction in FSH receptors in the rat testis by injection of homologous hormone., Mol Cell Endocrinol, 12, 9, 10.1016/0303-7207(78)90097-7 · DOI
  61. Granaprokasam, 1979, Receptor depletion and replenishment processes: in vivo regulation of gonadotropin receptors by luteinizing hormone, follicle-stimulating hormone and ethanol in rat testis., Biol Reprod, 20, 991, 10.1095/biolreprod20.5.991 · DOI
  62. O’Shaughnessy, 1980, FSH receptor autoregulation and cyclic AMP production in the immature rat testis., Biol Reprod, 23, 810, 10.1095/biolreprod23.4.810 · DOI
  63. Cao, 1982, Direct inhibition of testicular steroidogenesis and gonadotrophin receptors by [(imBzl)-D-His6,Pro9-NEt]GnRH and [D-Trp6,Pro9-NEt] GnRH, potent agonists of GnRH., Int J Androl, 5, 158, 10.1111/j.1365-2605.1982.tb00243.x · DOI
  64. Parmentier, 1989, Molecular cloning of the thyrotropin receptor., Science, 246, 1620, 10.1126/science.2556796 · DOI
  65. McFarland, 1989, Lutropin-choriogonadotropin receptor: an unusual member of the G protein-coupled receptor family., Science, 245, 494, 10.1126/science.2502842 · DOI
  66. Minegishi, 1991, Cloning and sequencing of human FSH receptor cDNA., Biochem Biophys Res Commun, 175, 1125, 10.1016/0006-291X(91)91682-3 · DOI
  67. Kelton, 1992, The cloning of the human follicle-stimulating hormone receptor and its expression in COS-7, CHO, and Y-1 cells., Mol Cell Endocrinol, 89, 141, 10.1016/0303-7207(92)90220-Z · DOI
  68. Albanese, 1994, Development of a bioassay for FSH using a recombinant human FSH receptor and a cAMP responsive luciferase reporter gene., Mol Cell Endocrinol, 101, 211, 10.1016/0303-7207(94)90237-2 · DOI
  69. Gromoll, 1993, Molecular cloning of the testicular follicle-stimulating hormone receptor of the non-human primate Macaca fascicularis and identification of multiple transcripts in the testis., Biochem Biophys Res Commun, 196, 1066, 10.1006/bbrc.1993.2359 · DOI
  70. Robert, 1994, Cloning and sequencing of the equine testicular follitropin receptor., Biochem Biophys Res Commun, 201, 201, 10.1006/bbrc.1994.1689 · DOI
  71. Yarney, 1993, Molecular cloning and expression of the ovine testicular follicle-stimulating hormone receptor., Mol Cell Endocrinol, 93, 219, 10.1016/0303-7207(93)90127-6 · DOI
  72. Remy, 1995, The porcine follitropin receptor: cDNA cloning, functional expression and chromosomal localization of the gene., Gene, 163, 257, 10.1016/0378-1119(95)00385-J · DOI
  73. Houde, 1994, Structure of the bovine follicle-stimulating hormone receptor complementary DNA and expression in bovine tissues., Mol Reprod Dev, 39, 127, 10.1002/mrd.1080390202 · DOI
  74. You, 1996, Characterization of the chicken follicle-stimulating hormone receptor (cFSH-R) complementary deoxyribonucleic acid, and expression of cFSH-R messenger ribonucleic acid in the ovary., Biol Reprod, 55, 1055, 10.1095/biolreprod55.5.1055 · DOI
  75. Akazome, 1996, Highly heterologous region in the N-terminal extracellular domain of reptilian follitropin receptors., Gen Comp Endocrinol, 104, 374, 10.1006/gcen.1996.0183 · DOI
  76. Kozac, 1989, The scanning model for translation: an update., J Cell Biol, 108, 229, 10.1083/jcb.108.2.229 · DOI
  77. Minegishi, 1994, Functional expression of the recombinant human FSH receptor., J Endocrinol, 141, 369, 10.1677/joe.0.1410369 · DOI
  78. Tilly, 1992, Expression of recombinant human follicle-stimulating hormone receptor: species-specific ligand binding, signal transduction, and identification of multiple ovarian messenger ribonucleic acid transcripts., Endocrinology, 131, 799
  79. Gromoll, 1992, Molecular cloning of a truncated isoform of the human follicle-stimulating hormone receptor., Biochem Biophys Res Commun, 188, 1077, 10.1016/0006-291X(92)91341-M · DOI
  80. Nothacker, 1993, Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals., Biochem Biophys Res Commun, 197, 1062, 10.1006/bbrc.1993.2586 · DOI
  81. Tensen, 1994, A G protein-coupled receptor with low density lipoprotein-binding motifs suggests a role for lipoproteins in G-linked signal transduction., Proc Natl Acad Sci USA, 91, 4816, 10.1073/pnas.91.11.4816 · DOI
  82. Hauser, 1997, Molecular cloning, genomic organization, and developmental regulation of a novel receptor from Drosophila melanogaster structurally related to members of the thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone/choriogonadotropin receptor family from mammals., J Biol Chem, 272, 1002, 10.1074/jbc.272.2.1002 · DOI
  83. Kobe, 1993, Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats., Nature, 366, 751, 10.1038/366751a0 · DOI
  84. Merz, 1992, Properties of glycoprotein hormone receptors and post-receptor mechanisms., Exp Clin Endocrinol, 100, 4, 10.1055/s-0029-1211164 · DOI
  85. Davis, 1995, Identification of the sites of N-linked glycosylation on the follicle-stimulating hormone (FSH) receptor and assessment of their role in FSH receptor function., Mol Endocrinol, 9, 159
  86. Braun, 1991, Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity., EMBO J, 10, 1885, 10.1002/j.1460-2075.1991.tb07714.x · DOI
  87. Baldwin, 1994, Structure and function of receptors coupled to G proteins., Curr Opin Biol, 6, 180, 10.1016/0955-0674(94)90134-1 · DOI
  88. Oliveira, 1993, A common motif in G-protein-coupled seven transmembrane helix receptors., J Comp Aid Mol Des, 7, 649, 10.1007/BF00125323 · DOI
  89. Christophe, 1993, Expression of the human follicle-stimulating hormone receptor in the baculovirus system., Biochem Biophys Res Commun, 196, 402, 10.1006/bbrc.1993.2263 · DOI
  90. Quintana, 1993, A polyclonal antibody to a synthetic peptide derived from the rat follicle-stimulating hormone receptor reveals the recombinant receptor as 74-kilodalton protein., Endocrinology, 133, 2098, 10.1210/endo.133.5.8404659 · DOI
  91. Dufau, 1995, The luteinizing hormone receptor., Curr Opin Endocrinol Diab, 2, 365, 10.1097/00060793-199510000-00001 · DOI
  92. Rousseau-Merck, 1993, The chromosomal localization of the human follicle-stimulating hormone receptor (FSHR) gene on 2 p21–p16 is similar to that of the luteinizing hormone receptor gene., Genomics, 15, 222, 10.1006/geno.1993.1041 · DOI
  93. Gromoll, 1994, Localization of the human FSH receptor to chromosome 2 p21 using a genomic probe comprising exon 10., J Mol Endocrinol, 12, 265, 10.1677/jme.0.0120265 · DOI
  94. Montgomery, 1995, The follicle-stimulating hormone receptor and luteinizing hormone receptor genes are closely linked in sheep and deer., J Mol Endocrinol, 15, 259, 10.1677/jme.0.0150259 · DOI
  95. Rousseau-Merck, 1990, Localization of the human luteinizing hormone receptor gene to chromosome 2 p21., Cytogenet Cell Genet, 54, 77, 10.1159/000132962 · DOI
  96. Rousseau-Merck, 1990, Assignment of the human thyroid stimulating hormone receptor to chromosome 14 q31., Genomics, 8, 233, 10.1016/0888-7543(90)90276-Z · DOI
  97. Lundin, 1993, Evolution of the vertebrate genome as reflected in paralogous chromosomal regions in man and in the mouse., Genomics, 16, 1, 10.1006/geno.1993.1133 · DOI
  98. Heckert, 1992, Structural organization of the follicle-stimulating hormone receptor gene., Mol Endocrinol, 6, 70
  99. Gromoll, 1996, The structure and organization of the human follicle-stimulating hormone receptor gene., Genomics, 35, 308, 10.1006/geno.1996.0361 · DOI
  100. Atger, 1995, Structure of the human luteinizing hormone choriogonadotropin receptor gene: unusual promoter and 5′ non-coding regions., Mol Cell Endocrinol, 111, 113, 10.1016/0303-7207(95)03557-N · DOI
  101. Gross, 1991, Composite structure of the human thyrotropin receptor gene., Biochem Biophys Res Commun, 177, 679, 10.1016/0006-291X(91)91842-Z · DOI
  102. Tsai-Morris, 1991, Structural organization of the rat luteinizing hormone receptor gene., J Biol Chem, 226, 11355, 10.1016/S0021-9258(18)99170-2 · DOI
  103. Koo, 1991, Structure of the luteinizing hormone receptor gene and multiple exons of the coding sequence., Endocrinology, 128, 2297, 10.1210/endo-128-5-2297 · DOI
  104. Dufau, 1995, Structure and regulation of the luteinizing hormone receptor gene., J Steroid Biochem Mol Biol, 53, 283, 10.1016/0960-0760(95)00115-G · DOI
  105. Linder, 1994, Follicle-stimulating hormone receptor gene promoter activity., Endocrine, 2, 957
  106. Gromoll, 1994, Characterization of the 5′ flanking region of the human follicle-stimulating hormone receptor gene., Mol Cell Endocrinol, 102, 93, 10.1016/0303-7207(94)90102-3 · DOI
  107. Huhtaniemi, 1992, The murine luteinizing hormone and follicle-stimulating hormone receptor genes: transcription initiation sites, putative promoter sequences and promoter activity., Mol Cell Endocrinol, 88, 55, 10.1016/0303-7207(92)90009-U · DOI
  108. Heckert, 1993, Expression of the FSH receptor in the testis., Recent Prog Horm Res, 48, 61, 10.1016/B978-0-12-571148-7.50006-3 · DOI
  109. Goetz, 1996, Role of E box and initiator region in the expression of the rat follicle-stimulating hormone receptor., J Biol Chem, 271, 33317, 10.1074/jbc.271.52.33317 · DOI
  110. Monaco, 1995, Pituitary follicle-stimulating hormone (FSH) induces CREM gene expression in Sertoli cells: involvement in long-term desensitization of the FSH receptor., Proc Natl Acad Sci USA, 92, 10673, 10.1073/pnas.92.23.10673 · DOI
  111. Griswold, 1995, The molecular biology of the FSH receptor., J Steroid Biochem Mol Biol, 53, 215, 10.1016/0960-0760(95)00049-6 · DOI
  112. Sites, 1994, Follicle-stimulating hormone (FSH) increases FSH receptor messenger ribonucleic acid while decreasing FSH binding in cultured porcine granulosa cells., Endocrinology, 134, 411, 10.1210/endo.134.1.8275955 · DOI
  113. Heckert, 1991, Expression of follicle-stimulating hormone receptor mRNA in rat testes and Sertoli cells., Mol Endocrinol, 5, 670, 10.1210/mend-5-5-670 · DOI
  114. Bacich, 1994, Characterization and relative abundance of alternatively spliced luteinizing hormone receptor messenger ribonucleic acid in the ovine ovary., Endocrinology, 135, 735, 10.1210/endo.135.2.7518389 · DOI
  115. Hsueh, 1992, Molecular basis of gonadotropin receptor regulation., Trends Endocrinol Metab, 3, 164, 10.1016/1043-2760(92)90166-X · DOI
  116. Rajapaksha, 1996, Expression of follicle-stimulating hormone receptor mRNA alternate transcripts in bovine granulosa cells during luteinization in vivo and in vitro., Mol Cell Endocrinol, 120, 25, 10.1016/0303-7207(96)03816-6 · DOI
  117. O’Shaughnessy, Dudley, 1993, Discrete splicing alternatives in mRNA encoding the extracellular domain of the testis FSH receptor in the normal and hypogonadal (hpg) mouse., J Endocrinol, 10, 363
  118. Tisdall, 1995, FSH receptor gene expression during ovarian follicle development in sheep., J Endocrinol, 15, 273
  119. Aatsinki, 1992, Expression of the LH/CG receptor gene in rat ovarian tissue is regulated by an extensive alternative splicing of the primary transcript., Mol Cell Endocrinol, 84, 127, 10.1016/0303-7207(92)90079-L · DOI
  120. Paschke, 1994, Presence of nonfunctional thyrotropin receptor variant transcripts in retroocular and other tissues., J Clin Endocrinol Metab, 79, 1234
  121. Khan, 1993, Cloning of alternative spliced mRNA transcripts coding for variants of ovine testicular follitropin receptor lacking the G protein coupling domains., Biochem Biophys Res Commun, 190, 888, 10.1006/bbrc.1993.1132 · DOI
  122. Themmen, 1994, Regulation of gonadotropin receptor gene expression., Mol Cell Endocrinol, 100, 15, 10.1016/0303-7207(94)90272-0 · DOI
  123. Baumann, 1995, Growth hormone binding to a circulating receptor fragment: the concept of receptor shedding and receptor splicing., Exp Clin Endocrinol, 103, 2, 10.1055/s-0029-1211322 · DOI
  124. Koo, 1994, Characterization of different sizes of rat luteinizing hormone/chorionic gonadotropin receptor messenger ribonucleic acids., Endocrinology, 134, 19, 10.1210/endo.134.1.8275933 · DOI
  125. Sairam, 1996, Follitropin signal transduction: alternative splicing of the FSH receptor gene produces a dominant negative form of receptor which inhibits hormone action., Biochem Biophys Res Commun, 226, 717, 10.1006/bbrc.1996.1419 · DOI
  126. Fritz, 1978, Sites of action of androgens and follicle-stimulating hormone on cells of the seminiferous tubule. In: Litwack G (ed) Biochemical Actions of Hormones., Academic Press, New York, vol, 5, 249
  127. Kangasniemi, 1990, Cellular regulation of follicle-stimulating hormone (FSH) binding in rat seminiferous tubules., J Androl, 11, 336, 10.1002/j.1939-4640.1990.tb00153.x · DOI
  128. Kliesch, 1992, Stage specific expression of the FSH receptor during rat spermatogenesis, Mol Cell Endocrinol, 84, R45, 10.1016/0303-7207(92)90039-9 · DOI
  129. Ranniki, 1995, Ontogeny of follicle-stimulating hormone receptor gene expression in the rat testis and ovary., Mol Cell Endocrinol, 107, 199, 10.1016/0303-7207(94)03444-X · DOI
  130. Dankbar, 1995, Ubiquitous expression of the androgen receptor and testis-specific expression of the FSH receptor in the cynomolgus monkey (Macaca fascicularis) revealed by a ribonuclease protection assay., J Steroid Biochem Mol Biol, 55, 35, 10.1016/0960-0760(95)00148-S · DOI
  131. Dankbar, 1995, Quantification of androgen receptor and follicle-stimulating hormone receptor mRNA levels in human and monkey testes by a ribonuclease protection assay., Int J Androl, 18, 88, 10.1111/j.1365-2605.1995.tb00391.x · DOI
  132. Ghinea, 1995, Transport of protein hormones through the vascular endothelium., J Endocrinol, 145, 1, 10.1677/joe.0.1450001 · DOI
  133. Huhtaniemi, 1987, Follicle-stimulating hormone receptors appear earlier in the primate fetal testis than in the ovary., Endocrinology, 65, 1210
  134. Goxe, 1993, Ontogeny of gonadal luteinizing hormone and follicle-stimulating hormone receptors in the fetal pig and related changes in gonadotropin and testosterone secretion., Biol Reprod, 49, 609, 10.1095/biolreprod49.3.609 · DOI
  135. Warren, 1984, Ontogeny of gonadotropin receptors in the fetal and neonatal rat testis., Endocrinology, 114, 470, 10.1210/endo-114-2-470 · DOI
  136. Tsutsui, 1985, Developmental changes in the binding of follicle-stimulating hormone (FSH) to testicular preparations of mice and the effects of hypo-physectomy and administration of FSH on the binding., Endocrinology, 117, 2534, 10.1210/endo-117-6-2534 · DOI
  137. Eskola, 1993, Age-related variation of follicle-stimulating hormone-stimulated cAMP production, protein kinase C activity and their interactions in the rat testis., Mol Cell Endocrinol, 93, 143, 10.1016/0303-7207(93)90117-3 · DOI
  138. Ito, 1993, Developmental changes of testicular activin and FSH receptor mRNA and plasma FSH and inhibin levels in the rat., Life Sci, 53, 1299, 10.1016/0024-3205(93)90575-N · DOI
  139. Shiraishi, 1993, Developmental changes of testicular gonadotropin receptors and serum gonadotropin levels in two strains of mice., Zool Sci, 10, 497
  140. Almiron, 1988, Spermatogenic onset. II. FSH modulates mitotic activity of germ and Sertoli cells in immature rats., Int J Androl, 11, 235, 10.1111/j.1365-2605.1988.tb00998.x · DOI
  141. Tsutsui, 1988, Effects of photoperiod and temperature on the binding of follicle-stimulating hormone (FSH) to testicular preparations and plasma FSH concentration in the Djungarian hamster, Phodopus sungorus., Endocrinology, 122, 1094, 10.1210/endo-122-3-1094 · DOI
  142. Tsutsui, 1992, Binding properties and photoperiodic influence of follicle-stimulating hormone receptors in the subtropical wild quail., Zool Sci, 9, 649
  143. Maguire, 1996, Regulation of the follicle-stimulating hormone receptor mRNA by follicle-stimulating hormone and testosterone in cultured Sertoli cells and hypophysectomised rats
  144. Themmen, 1991, Follitropin receptor down-regulation involves a cAMP-dependent post transcriptional decrease of receptor mRNA expression, Mol Cell Endocrinol, 78, R7, 10.1016/0303-7207(91)90130-K · DOI
  145. Rannikko, 1996, Stage-specific expression of the follicle-stimulating hormone receptor gene in the rat seminiferous epithelium
  146. Parvinen, 1993, Cyclic functions of Sertoli cells, In: Russell LD, Griswold MD (eds) The Sertoli Cell. Cache River Press, Clearwater, FL, pp, 331
  147. Weinbauer, 1993, Hormonal control of spermatogenesis, In: De Kretser D (ed) Molecular Biology of the Male Reproductive System. Academic Press, San Diego, CA, pp, 99
  148. Richards, 1976, Protein hormone action: a key to understanding ovarian follicular and luteal cell development., Biol Reprod, 14, 82, 10.1095/biolreprod14.1.82 · DOI
  149. Richards, 1980, Maturation of ovarian follicles: actions and interaction of pituitary and ovarian hormones on follicular cell differentiation., Physiol Rev, 60, 51, 10.1152/physrev.1980.60.1.51 · DOI
  150. Camp, 1991, Cellular localization and hormonal regulation of follicle-stimulating hormone and luteinizing hormone receptor messenger RNAs in the rat ovary., Mol Endocrinol, 5, 1405, 10.1210/mend-5-10-1405 · DOI
  151. Tilly, 1992, Hormonal regulation of follicle-stimulating hormone receptor messenger ribonucleic acid levels in cultured rat granulosa cells., Endocrinology, 130, 1296
  152. Zheng, 1996, Follicle-stimulating hormone receptor is expressed in human ovarian surface epithelium and fallopian tube., Am J Pathol, 148, 47
  153. Lei, 1994, Novel presence of luteinizing hormone/human chorionic gonadotropin (hCG) receptors and the down-regulating action of hCG on gonadotropin releasing hormone gene expression in immortalized hypothalamic GT1–7 neurons., Mol Endocrinol, 8, 1111
  154. Korneyi, 1996, Restoration of human chorionic gonadotropin response in human myometrial smooth muscle cells by treatment with follicle-stimulating hormone (FSH): evidence for the presence of FSH receptors in human myometrium., Eur J Endocrinol, 134, 225, 10.1530/eje.0.1340225 · DOI
  155. Adashi, 1994, Endocrinology of the ovary., Hum Reprod, 5, 815, 10.1093/oxfordjournals.humrep.a138602 · DOI
  156. O’Shaughnessy, 1994, Follicle-stimulating hormone receptor mRNA in the mouse ovary during post-natal development in the normal mouse and in the adult hypogonadal (hpg) mouse: structure of alternate transcripts., Mol Cell Endocrinol, 101, 197, 10.1016/0303-7207(94)90235-6 · DOI
  157. Sokka, 1990, Ontogeny of gonadotrophin receptors and gonadotrophin-stimulated cAMP production in the neonatal rat ovary., J Endocrinol, 127, 297, 10.1677/joe.0.1270297 · DOI
  158. Dunkel, 1994, Follicle-stimulating hormone receptor expression in the rat ovary: increases during prepubertal development and regulation by opposing actions of transforming growth factors β and α., Biol Reprod, 50, 940, 10.1095/biolreprod50.4.940 · DOI
  159. LaPolt, 1992, Gonadotropin-induced up- and down-regulation of ovarian follicle-stimulating hormone (FSH) receptor gene expression in immature rats: effects of pregnant mare’s serum gonadotropin, human chorionic gonadotropin, and recombinant FSH., Endocrinology, 130, 1289
  160. Nakamura, 1991, Hormonal regulation of gonadotropin receptor mRNA in rat ovary during follicular growth and luteinization., Mol Cell Endocrinol, 82, 259, 10.1016/0303-7207(91)90039-U · DOI
  161. Galway, 1990, Recombinant FSH induces ovulation and tissue plasminogen activator expression in hypophysectomized rats., Endocrinology, 127, 3023, 10.1210/endo-127-6-3023 · DOI
  162. Ritzhaupt, 1987, A decrease in FSH receptors of granulosa cells during follicular maturation in the domestic hen., J Endocrinol, 115, 303, 10.1677/joe.0.1150303 · DOI
  163. Uilenbroek, 1979, Ovarian follicular development during the rat estrous cycle: gonadotropin receptors and follicular responsiveness., Biol Reprod, 20, 1159, 10.1095/biolreprod20.5.1159 · DOI
  164. Xu, 1995, Expression of follicle-stimulating hormone and luteinizing hormone receptor messenger ribonucleic acids in bovine follicles during the first follicular wave., Biol Reprod, 53, 951, 10.1095/biolreprod53.4.951 · DOI
  165. LaBarbera, 1994, Follicle-stimulating hormone (FSH) receptors and FSH-responsive adenosine 3′, 5′-cyclic monophosphate production in porcine granulosa cells decline with follicular growth., Endocr Res, 20, 65, 10.1080/07435809409035857 · DOI
  166. Tilly, 1992, Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase., Endocrinology, 131, 1670, 10.1210/endo.131.4.1396312 · DOI
  167. Tsutsui, 1992, Inhibitory role of sex steroid in the regulation of ovarian follicle-stimulating hormone receptors during pregnancy., J Exp Zool, 264, 167, 10.1002/jez.1402640208 · DOI
  168. Kermabon, 1995, Gonadotropins in lactating sows exposed to long or short days during pregnancy and lactation: serum concentrations and ovarian receptors., Biol Reprod, 53, 1095, 10.1095/biolreprod53.5.1095 · DOI
  169. Vihko, 1996, Gonadotropins and gonadotropin receptors during peri-menopause., Eur J Endocrinol, 134, 357, 10.1530/eje.0.1340357 · DOI
  170. Nakamura, 1993, Effect of activin A on follicle-stimulating hormone (FSH) receptor messenger ribonucleic acid levels and FSH receptor expression in cultured rat granulosa cells., Endocrinology, 133, 538, 10.1210/endo.133.2.8393766 · DOI
  171. Nakamura, 1995, Interaction between activin A and cAMP in the induction of FSH receptor in cultured rat granulosa cells., J Endocrinol, 147, 103, 10.1677/joe.0.1470103 · DOI
  172. Minegishi, 1996, Regulation of follicle-stimulating hormone receptor., Horm Res, 46, 37, 10.1159/000185180 · DOI
  173. Xiao, 1992, Effects of activin and follicle-stimulating hormone (FSH)-suppression protein/follistatin on FSH receptors and differentiation of cultured rat granulosa cells., Endocrinology, 131, 1009, 10.1210/endo.131.3.1505447 · DOI
  174. Shibata, 1992, Evidence that the FSH receptor itself is not a calcium channel., Endocrinology, 131, 979
  175. Mulder, 1994, The species-specificity of the recombinant human and rat follicle-stimulating hormone receptor are similar., Endocrine, 2, 25
  176. Quintana, 1994, Follitropin (FSH) and phorbol ester stimulate the phosphorylation of the FSH receptor in intact cells., J Biol Chem, 269, 8772, 10.1016/S0021-9258(17)37035-7 · DOI
  177. Hipkin, 1995, Truncation of the C-terminal tail of the follitropin receptor does not impair the agonist- or phorbol ester-induced receptor phosphorylation and uncoupling., J Biol Chem, 270, 26683, 10.1074/jbc.270.44.26683 · DOI
  178. Ji, 1995, Differential roles of exoloop 1 of the human follicle-stimulating hormone receptor in hormone binding and receptor activation., J Biol Chem, 270, 15970, 10.1074/jbc.270.27.15970 · DOI
  179. Schipper, 1996, Application of a CHO cell line transfected with the human FSH receptor for the measurement of specific FSH receptor activation inhibitors in human serum., J Endocrinol, 150, 505, 10.1677/joe.0.1500505 · DOI
  180. Keren-Tal, 1993, Establishment of steroidogenic granulosa cell lines expressing follicle-stimulating hormone receptors, Mol Cell Endocrinol, 95, R1, 10.1016/0303-7207(93)90042-I · DOI
  181. Liu, 1994, Accessibility of rat and human follitropin receptor primary sequence (R265–S296) in situ., Endocrinology, 135, 682, 10.1210/endo.135.2.8033817 · DOI
  182. Gudermann, 1994, In vitro bioassay for human follicle-stimulating hormone (FSH) based on L cells transfected with recombinant rat FSH receptor: validation of a model system., Endocrinology, 135, 2204, 10.1210/endo.135.5.7956943 · DOI
  183. Simoni, 1993, Biological and immunological properties of the international standard for FSH 83/575: isoelectrofocusing profile and comparison with other FSH preparations., Acta Endocrinol (Copenh), 128, 281, 10.1530/acta.0.1280281 · DOI
  184. Simoni, 1994, Polymorphism of human pituitary FSH: analysis of immunoreactivity and in-vitro bioactivity of different molecular species., J Endocrinol, 141, 359, 10.1677/joe.0.1410359 · DOI
  185. Andersen, 1983, Follitropin binding to receptors in testis: studies on the reversibility and thermodynamics of the reaction., Mol Cell Endocrinol, 33, 37, 10.1016/0303-7207(83)90055-2 · DOI
  186. van Loenen, 1994, Follicle-stimulating hormone stimulates rat Sertoli cells via relatively low affinity binding sites., Endocrine, 2, 1023
  187. van Loenen, 1994, High affinity FSH receptor binding is a slowly nonreversible process that appears not to be important for rapid receptor activation., Endocrine, 2, 1031
  188. Simoni, 1991, In vitro bioassays for follicle-stimulating hormone: methods and clinical applications., J Endocrinol Invest, 14, 983, 10.1007/BF03347131 · DOI
  189. Walther, 1996, Sertoli cell lines established from H-Kb-tsA58 transgenic mice differentially regulate the expression of cell-specific genes., Exp Cell Res, 225, 411, 10.1006/excr.1996.0192 · DOI
  190. Tano, 1995, Application of Chinese hamster ovary cells transfected with recombinant human follicle-stimulating hormone (FSH) receptor for measurement of serum FSH., Fertil Steril, 64, 1120, 10.1016/S0015-0282(16)57971-0 · DOI
  191. Christin-Maitre, 1996, Homologous in vitro bioassay for follicle-stimulating hormone (FSH) reveals increased FSH biological signal during the mid- to late luteal phase of the human menstrual cycle., J Clin Endocrinol Metab, 81, 2080
  192. Leifke, 1997, Does the gonadotropic axis play a role in the pathogenesis of Sertoli cell only syndrome?, Int J Androl, 20, 29, 10.1046/j.1365-2605.1997.00102.x · DOI
  193. Anasti, 1995, The use of human recombinant gonadotropin receptors to search for immunoglobulin G-mediated premature ovarian failure., J Clin Endocrinol Metab, 80, 824
  194. Simoni, 1997, Stable expression of the human FSH receptor in a mouse Sertoli cell line: a model to study FSH action, 721
  195. Rozell, 1995, Intracellular retention of mutant gonadotropin receptors results in loss of hormone binding activity of the follitropin receptor but not the lutropin/choriogonadotropin receptor., Mol Endocrinol, 9, 1727
  196. Sanchez-Yague, 1993, Biochemical properties of the agonist induced desensitization of the follicle-stimulating hormone and luteinizing hormone/chorionic gonadotropin-responsive adenylyl cyclase in cells expressing the recombinant gonadotropin receptors., Endocrinology, 132, 1007, 10.1210/endo.132.3.8440169 · DOI
  197. Sharma, 1995, Expression of the extracellular domain peptides of the FSH receptor and their effect on receptor-ligand interactions in vitro., Mol Cell Endocrinol, 115, 87, 10.1016/0303-7207(95)03673-U · DOI
  198. Kudo, 1996, Transmembrane regions V to VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop., J Biol Chem, 37, 22470, 10.1074/jbc.271.37.22470 · DOI
  199. Zhu, 1994, Dual signal potential is common among Gs-coupled receptors and dependent on receptor density., Mol Pharmacol, 46, 460, 10.1016/S0026-895X(25)09722-6 · DOI
  200. Dattatreyamurty, 1992, Carbohydrate moiety of follitropin receptor is not required for high affinity hormone-binding for functional coupling between receptor and guanine nucleotide-binding protein in bovine calf testis membranes., Endocrinology, 131, 2437, 10.1210/endo.131.5.1425441 · DOI

200 of 391 shown

Cited by

Sorted by citations

Metadata

Authors
Simoni, M., Gromoll, J., & Nieschlag, E.
Affiliations
Institute of Reproductive Medicine of the University, Domagkstraße 11, D-48129 Münster, Germany
Venue
Endocrine Reviews
Publisher
The Endocrine Society
Published
1997-12-01
Volume
18
Issue
6
Pages
739-773
ISSN
  • 0163-769X
  • 1945-7189
DOI
10.1210/edrv.18.6.0320
Cited by
82
References
1
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review