Characterization of the Biological Roles of the Estrogen Receptors, ERα and ERβ, in Estrogen Target Tissues in Vivo through the Use of an ERα-Selective Ligand

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

Kuiper, G. G. J. M., Carlsson, B., Grandien, K., Enmark, E., Häggblad, J., Nilsson, S., & Gustafsson, J.-A. (1997) · Endocrinology · doi:10.1210/endo.138.3.4979 · Cited by 4,442

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

Couse, J. F., & Korach, K. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0370 · Cited by 2,045

Estrogen Actions in the Central Nervous System

McEwen, B. S., & Alves, S. E. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0365 · Cited by 1,504

The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens1

Hall, J. M., & McDonnell, D. P. (1999) · Endocrinology · doi:10.1210/endo.140.12.7179 · Cited by 1,078

Effect of single and compound knockouts of estrogen receptors α (ERα) and β (ERβ) on mouse reproductive phenotypes

Dupont, S., Krust, A., Gansmuller, A., Dierich, A., Chambon, P., & Mark, M. (2000) · Development · doi:10.1242/dev.127.19.4277 · Cited by 1,064

Pyrazole Ligands: Structure−Affinity/Activity Relationships and Estrogen Receptor-α-Selective Agonists

Stauffer, S. R., Coletta, C. J., Tedesco, R., Nishiguchi, G., Carlson, K. E., Sun, J., Katzenellenbogen, B. S., & Katzenellenbogen, J. A. (2000) · Journal of Medicinal Chemistry · doi:10.1021/jm000170m · Cited by 760

Role of Estrogen Receptor Beta in Estrogen Action

Pettersson, K., & Gustafsson, J.-Α. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.165 · Cited by 491

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene

Couse, J. F., Curtis, S. W., Washburn, T. F., Lindzey, J. K., GOLDING, T. S., Lubahn, D. B., Smithies, O., & Korach, K. S. (1995) · Molecular Endocrinology · doi:10.1210/mend.9.11.8584021 · Cited by 454

The Estrogen Receptor β Subtype: A Novel Mediator of Estrogen Action in Neuroendocrine Systems

Kuiper, G. G. J. M., Shughrue, P. J., Merchenthaler, I. J., & Gustafsson, J.-Α. (1998) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1998.0170 · Cited by 438

Oestrogen receptors – an overview

Enmark, E., & Gustafsson, J.-Α. (1999) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1999.00545.x · Cited by 377

Estradiol enhances object recognition memory in Swiss female mice by activating hippocampal estrogen receptor α.

Pereira, L. M., Bastos, C. P., de Souza, J. M., Ribeiro, F. M., & Pereira, G. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.04.001 · Cited by 66

The Glycolytic Enzyme PFKFB3 Is Involved in Estrogen-Mediated Angiogenesis via GPER1

Trenti, A., Tedesco, S., Boscaro, C., Ferri, N., Cignarella, A., Trevisi, L., & Bolego, C. (2017) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.116.238212 · Cited by 61

WAY-202196, a selective estrogen receptor-beta agonist, protects against death in experimental septic shock

Cristofaro, P. A., Opal, S. M., Palardy, J. E., Parejo, N. A., Jhung, J. W., Keith, J. C., & Harris, H. A. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000227173.13497.56 · Cited by 61

Oestrogen receptor‐alpha activation augments post‐exercise myoblast proliferation

Thomas, A., Bunyan, K., & Tiidus, P. M. (2009) · Acta Physiologica · doi:10.1111/j.1748-1716.2009.02033.x · Cited by 60

High-soy diet decreases infarct size after permanent middle cerebral artery occlusion in female rats

Schreihofer, D. A., Do, K. D., & Schreihofer, A. M. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00642.2004 · Cited by 60

Oestrogen receptor α agonist improved long-term ovariectomy-induced spatial cognition deficit in young rats

Qu, N., Wang, L., Liu, Z.-C., Tian, Q., & Zhang, Q. (2012) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145712000958 · Cited by 59

Correlation between in Vitro Peptide Binding Profiles and Cellular Activities for Estrogen Receptor-Modulating Compounds

Iannone, M. A., Simmons, C. A., Kadwell, S. H., Svoboda, D. L., Vanderwall, D. E., Deng, S.-J., Consler, T. G., Shearin, J., Gray, J. G., & Pearce, K. H. (2004) · Molecular Endocrinology · doi:10.1210/me.2003-0432 · Cited by 59

Postovariectomy weight gain in female rats is reversed by estrogen receptor α agonist, propylpyrazoletriol

Wegorzewska, I., Walters, K., Weiser, M. J., Cruthirds, D. F., Ewell, E., Larco, D. O., Handa, R. J., & Wu, T. J. (2008) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2007.11.054 · Cited by 57

Amelioration of collagen‐induced arthritis and immune‐associated bone loss through signaling via estrogen receptor α, and not estrogen receptor β or G protein–coupled receptor 30

Engdahl, C., Jochéms, C., Windahl, S. H., Börjesson, A., Ohlsson, C., Carlsten, H., & Lagerquist, M. K. (2010) · Arthritis & Rheumatism · doi:10.1002/art.25055 · Cited by 58

Estrogen Modulates Endothelial and Neuronal Nitric Oxide Synthase Expression via an Estrogen Receptor β-Dependent Mechanism in Hypothalamic Slice Cultures

Gingerich, S., & Krukoff, T. L. (2005) · Endocrinology · doi:10.1210/en.2004-1375 · Cited by 56

Estrogen Receptor Pathway Is Involved in the Regulation of Calbindin-D9k in the Uterus of Immature Rats

Lee, G.-S. (2005) · Toxicological Sciences · doi:10.1093/toxsci/kfi072 · Cited by 56

Regulation of Estrogen Receptor (ER) Isoform Messenger RNA Expression by Different ER Ligands in Female Rat Pituitary1

Tena‐Sempere, M., Navarro, V. M., Mayen, A., Bellido, C., & Sánchez‐Criado, J. E. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.103.021378 · Cited by 56

ESR1 and ESR2 Differentially Regulate Daily and Circadian Activity Rhythms in Female Mice

Royston, S. E., Yasui, N., Kondilis, A., Lord, S., Katzenellenbogen, J. A., & Mahoney, M. M. (2014) · Endocrinology · doi:10.1210/en.2014-1101 · Cited by 55

Contribution of estrogen receptors alpha and beta in the brain response to traumatic brain injury

Zahediasl, S., Khaksari, M., khachki, A. S., Shahrokhi, N., & Nourizade, S. (2013) · Journal of neurosurgery · doi:10.3171/2013.4.jns121636 · Cited by 54

Female sexual behavior, estrous cycle and gene expression in sexually dimorphic brain regions after pre- and postnatal exposure to endocrine active UV filters

Faass, O., Schlumpf, M., Reolon, S., Henseler, M., Maerkel, K., Durrer, S., & LICHTENSTEIGER, W. (2008) · NeuroToxicology · doi:10.1016/j.neuro.2008.12.008 · Cited by 54

Modulation of responses to stress by estradiol benzoate and selective estrogen receptor agonists

Serova, L. I., Harris, H. A., Maharjan, S., & Sabban, E. L. (2010) · Journal of Endocrinology · doi:10.1677/joe-10-0029 · Cited by 57

Oestrogen receptor β ligand acts on CD11c+ cells to mediate protection in experimental autoimmune encephalomyelitis

Kim, R. Y., Mangu, D., Hoffman, A., Kavosh, R., Jung, E., Itoh, N., & Voskuhl, R. R. (2017) · Brain · doi:10.1093/brain/awx315 · Cited by 54

Dietary Acrylamide Intake and Brain Cancer Risk

Hogervorst, J. G. F., Schouten, L. J., Konings, E. J. M., Goldbohm, R. A., & van den Brandt, P. A. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-1133 · Cited by 54

Effects of estrogen receptor subtype-selective agonists on immune functions in ovariectomized mice

Li, J., & McMurray, R. W. (2006) · International Immunopharmacology · doi:10.1016/j.intimp.2006.04.019 · Cited by 53

Effects of 8-prenylnaringenin on the hypothalamo-pituitary-uterine axis in rats after 3-month treatment

Christoffel, J., Rimoldi, G., & Wuttke, W. (2006) · Journal of Endocrinology · doi:10.1677/joe.1.06384 · Cited by 56

Estrogen receptors beta and alpha have specific pro- and anti-nociceptive actions.

Coulombe, M., Spooner, M., Gaumond, I., Carrier, J. C., & Marchand, S. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.02.057 · Cited by 53

Estradiol after Cardiac Arrest and Cardiopulmonary Resuscitation is Neuroprotective and Mediated through Estrogen Receptor-β

Noppens, R. R., Kofler, J., Grafe, M. R., Hurn, P. D., & Traystman, R. J. (2008) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2008.116 · Cited by 51

Estrogen Receptor-α But Not -β or GPER Inhibits High Glucose-Induced Human VSMC Proliferation: Potential Role of ROS and ERK

Ortmann, J., Veit, M., Zingg, S., Santo, S. D., Traupe, T., Yang, Z., Völzmann, J., Dubey, R. K., Christen, S., & Baumgärtner, I. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0943 · Cited by 51

Minireview: Modulation of Hormone Receptor Signaling by Dietary Anticancer Indoles

Firestone, G. L., & Sundar, S. N. (2009) · Molecular Endocrinology · doi:10.1210/me.2009-0149 · Cited by 50

Estrogen stimulates transcription from the human prolactin distal promoter through AP1 and estrogen responsive elements in T47D human breast cancer cells

Duan, R., Ginsburg, E., & Vonderhaar, B. K. (2007) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2007.10.004 · Cited by 48

Estrogen receptor subtypes selectively mediate female mouse reproductive abnormalities induced by neonatal exposure to estrogenic chemicals

Nakamura, T., Katsu, Y., Watanabe, H., & Iguchi, T. (2008) · Toxicology · doi:10.1016/j.tox.2008.09.006 · Cited by 46

Estrogen and estrogen receptors in the modulation of gastrointestinal epithelial secretion

Yang, X., Guo, Y., He, J., Zhang, F., Sun, X., Yang, S., & Dong, H. (2017) · Oncotarget · doi:10.18632/oncotarget.18313 · Cited by 46

Activation of estrogen receptor-β by a special extract of Rheum rhaponticum (ERr 731®), its aglycones and structurally related compounds

Wober, J., Möller, F. J., Richter, T., Unger, C., Weigt, C., Jandausch, A., Zierau, O., Rettenberger, R., Kaszkin-Bettag, M., & Vollmer, G. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.04.002 · Cited by 46

Estrogen receptor α and β polymorphisms

Silvestri, S., Thomsen, A. B., Gozzini, A., Bagger, Y. Z., Christiansen, C., & Brandi, M. L. (2006) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000182804.14385.a2 · Cited by 45

Estrogen-induced hypomethylation and overexpression of YAP1 facilitate breast cancer cell growth and survival

Muhammad, J. S., Guimei, M. M., Jayakumar, M. N., Shafarin, J., Janeeh, A. S., AbuJabal, R., Eladl, M. A., Ranade, A. V., Ali, A., & Hamad, M. A. (2020) · Neoplasia · doi:10.1016/j.neo.2020.11.002 · Cited by 48

Organ Messenger Ribonucleic Acid and Plasma Proteome Changes in the Adjuvant-Induced Arthritis Model: Responses to Disease Induction and Therapy with the Estrogen Receptor-β Selective Agonist ERB-041

Follettie, M. T., Pinard, M., Keith, J. C., Wang, L., Chelsky, D., Hayward, C., Kearney, P., Thibault, P., Paramithiotis, E., Dorner, A. J., et al. (2005) · Endocrinology · doi:10.1210/en.2005-0600 · Cited by 45

Knee ligament mechanical properties are not influenced by estrogen or its receptors

Warden, S. J., Saxon, L., Castillo, A. B., & Turner, C. H. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00367.2005 · Cited by 45

Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis

Denk, F., Ramer, L. M., Erskine, E. L. K. S., Nassar, M. A., Bogdanov, Y., Signore, M., Wood, J. N., McMahon, S. B., & Ramer, M. S. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0255-6 · Cited by 45

Estradiol Stimulates Capillary Formation by Human Endothelial Progenitor Cells

Baruscotti, I., Barchiesi, F., Jackson, E. K., Imthurn, B., Stiller, R., Kim, J.-H., Schaufelberger, S., Rosselli, M., Hughes, C. C. W., & Dubey, R. K. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.153262 · Cited by 44

Soluble Frizzled-Related Protein 1 Is Estrogen Inducible in Bone Marrow Stromal Cells and Suppresses the Earliest Events in Lymphopoiesis

Yokota, T., Oritani, K., Garrett, K. P., Kouro, T., Nishida, M., Takahashi, I., Ichii, M., Satoh, Y., Kincade, P. W., & Kanakura, Y. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.9.6061 · Cited by 45

Indole-3-Carbinol Selectively Uncouples Expression and Activity of Estrogen Receptor Subtypes in Human Breast Cancer Cells

Sundar, S. N., Kerekatte, V., Equinozio, C. N., Doan, V. B., Bjeldanes, L. F., & Firestone, G. L. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0263 · Cited by 44

Studies on estrogen receptor (ER) α and β responses on gene regulation in peripheral blood leukocytes in vivo using selective ER agonists

Stygar, D., Masironi, B., Eriksson, H., & Sahlin, L. (2007) · Journal of Endocrinology · doi:10.1677/joe-06-0060 · Cited by 44

7-Substituted 2-phenyl-benzofurans as ERβ selective ligands

Collini, M. D., Kaufman, D. H., Manas, E. S., Harris, H. A., Henderson, R. A., Xu, Z. B., Unwalla, R. J., & Miller, C. P. (2004) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2004.07.029 · Cited by 44

Estrogens contribute to a sex difference in plasma potassium concentration: A mechanism for regulation of adrenal angiotensin receptors

Zheng, W., Shi, M., You, S.-E., Ji, H., & Roesch, D. M. (2006) · Gender Medicine · doi:10.1016/s1550-8579(06)80193-2 · Cited by 43

Estrogen-Like Disruptive Effects of Dietary Exposure to Bisphenol A or 17α-Ethinyl Estradiol in CD1 Mice

Kendig, E. L., Buesing, D. R., Christie, S. M., Cookman, C. J., Gear, R. B., Hugo, E. R., Kasper, S. N., Kendziorski, J. A., Ungi, K. R., Williams, K., et al. (2012) · International Journal of Toxicology · doi:10.1177/1091581812463254 · Cited by 43

Activation of Estrogen Receptor G Protein–Coupled Receptor 30 Enhances Cholesterol Cholelithogenesis in Female Mice

Wang, H. H., de Bari, O., Arnatt, C. K., Liu, M., Portincasa, P., & Wang, D. Q. ‐. (2020) · Hepatology · doi:10.1002/hep.31212 · Cited by 43

Selective estrogen receptor‐α agonist provides widespread heart and vascular protection with enhanced endothelial progenitor cell mobilization in the absence of uterotrophic action

Bolego, C., Rossoni, G., Fadini, G. P., Vegeto, E., Pinna, C., Albiero, M., Boscaro, E., Agostini, C., Avogaro, A., Gaion, R. M., et al. (2010) · The FASEB Journal · doi:10.1096/fj.09-139220 · Cited by 43

The discovery of tetrahydrofluorenones as a new class of estrogen receptor β-subtype selective ligands

Wilkening, R. R., Ratcliffe, R. W., Tynebor, E. C., Wildonger, K. J., Fried, A. K., Hammond, M. L., Mosley, R. T., Fitzgerald, P. M. D., Sharma, N., McKeever, B. M., et al. (2006) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2006.03.098 · Cited by 43

Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro

Zheng, N., Liu, L., Liu, W., Li, F., Hayashi, T., Tashiro, S., Onodera, S., & Ikejima, T. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2016.117 · Cited by 42

Mining the Complexities of the Estrogen Signaling Pathways for Novel Therapeutics

McDonnell, D. P. (2003) · Endocrinology · doi:10.1210/en.2003-0900 · Cited by 42

Insights into Ligand Selectivity in Estrogen Receptor Isoforms: Molecular Dynamics Simulations and Binding Free Energy Calculations

Zeng, J., Li, W., Zhao, Y., Liu, G., Tang, Y., & Jiang, H. (2008) · The Journal of Physical Chemistry B · doi:10.1021/jp710029r · Cited by 41

Chemopreventive effect of ERβ‐Selective agonist on intestinal tumorigenesis in ApcMin/+ Mice

Giroux, V., Bernatchez, G., & Carrier, J. C. (2010) · Molecular Carcinogenesis · doi:10.1002/mc.20719 · Cited by 41

Evidence of reproductive disruption associated with neuroendocrine changes induced by UV–B filters, phtalates and nonylphenol during sexual maturation in rats of both gender

Ponzo, O., & Carbone, S. (2013) · Toxicology · doi:10.1016/j.tox.2013.05.014 · Cited by 41

Transcriptional regulation by phytoestrogens in neuronal cell lines

Schreihofer, D. A. (2005) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2004.12.006 · Cited by 41

Tissue- and hormone- dependent progesterone receptor distribution in the rat uterus

Sahlin, L., Masironi, B., Åkerberg, S., & Eriksson, H. (2006) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-4-47 · Cited by 41

Structure–activity relationships and sub-type selectivity in an oxabicyclic estrogen receptor α/β agonist scaffold

Hamann, L. G., Meyer, J. H., Ruppar, D. A., Marschke, K. B., LÓPEZ, F. J., Allegretto, E. A., & Karanewsky, D. S. (2005) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2004.12.077 · Cited by 41

Uterotropic effects of dietary equol administration in ovariectomized Sprague–Dawley rats

Rachoń, D., Vortherms, T., Seidlová‐Wuttke, D., Menche, A., & Wuttke, W. (2007) · Climacteric · doi:10.1080/13697130701624757 · Cited by 40

Estrogen receptor (ER) subtype agonists alter monoamine levels in the female rat brain

Lubbers, L. S., Zafian, P., Gautreaux, C., Gordon, M., Alves, S. E., Correa, L. D., Lorrain, D. S., Hickey, G. J., & Luine, V. N. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.08.005 · Cited by 40

Estrogen Receptor β Agonism Increases Survival in Experimentally Induced Sepsis and Ameliorates the Genomic Sepsis Signature: A Pharmacogenomic Study

Christaki, E., Opal, S. M., Keith, J. C., Kessinian, N., Palardy, J. E., Parejo, N. A., LaVallie, E. R., Collins‐Racie, L. A., Mounts, W. M., Malamas, M. S., et al. (2010) · The Journal of Infectious Diseases · doi:10.1086/651276 · Cited by 39

Systemic administration of diarylpropionitrile (DPN) or phytoestrogens does not affect anxiety-related behaviors in gonadally intact male rats

Patisaul, H. B., Burke, K. T., Hinkle, R. E., Adewale, H. B., & Shea, D. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2008.11.004 · Cited by 38

Estrogen and folliculogenesis: is one necessary for the other?

Kolibianakis, E. M., Papanikolaou, E. G. E., Fatemi, H. M., & Devroey, P. (2005) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/01.gco.0000169101.83342.96 · Cited by 38

Confirmation of the efficacy of ERr 731 in perimenopausal women with menopausal symptoms.

Kaszkin-Bettag, M., Ventskovskiy, B. M., Solskyy, S., Beck, S., Hasper, I., Kravchenko, A. A., Rettenberger, R., Richardson, A., & Heger, P. W. (2009) · PubMed · Cited by 38

Impact of estrogen receptor alpha and beta agonists on delayed alternation in middle-aged rats

Neese, S. L., Korol, D. L., Katzenellenbogen, J. A., & Schantz, S. L. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.08.017 · Cited by 37

Activation of ERβ modulates fear generalization through an effect on memory retrieval.

Lynch, J., Dejanovic, D., Winiecki, P., Mulvany, J., Ortiz, S., Riccio, D., & Jasnow, A. (2014) · Hormones and Behavior · doi:10.1016/j.yhbeh.2014.06.017 · Cited by 39

Effects of Long-Term Treatment with Estradiol and Estrogen Receptor Subtype Agonists on Serotonergic Function in Ovariectomized Rats

Benmansour, S., Adeniji, O. S., Privratsky, A. A., & Frazer, A. (2015) · Neuroendocrinology · doi:10.1159/000437268 · Cited by 36

Estrogenic Activity of Anthraquinone Derivatives:In VitroandIn SilicoStudies

Li, F., Li, X., Shao, J., Chi, P., Chen, J., & Wang, Z. (2010) · Chemical Research in Toxicology · doi:10.1021/tx100118g · Cited by 36

The Expression of Aromatase in Gonadotropes Is Regulated by Estradiol and Gonadotropin-Releasing Hormone in a Manner that Differs from the Regulation of Luteinizing Hormone

Galmiche, G., Richard, N., Corvaisier, S., & Kottler, M. (2006) · Endocrinology · doi:10.1210/en.2005-1650 · Cited by 36

Dietary daidzein and puerarin do not affect pituitary LH expression but exert uterotropic effects in ovariectomized rats

Rachoń, D., Vortherms, T., Seidlová‐Wuttke, D., & Wuttke, W. (2007) · Maturitas · doi:10.1016/j.maturitas.2006.12.003 · Cited by 36

Estrogen receptor-α signaling in tanycytes lies at the crossroads of fertility and metabolism

Fernandois, D., Rusidzé, M., Müller‐Fielitz, H., Sauvé, F., Deligia, E., Silva, M. S. B., Evrard, F., Franco‐García, A., Mazur, D., Martínez‐Corral, I., et al. (2024) · Metabolism · doi:10.1016/j.metabol.2024.155976 · Cited by 35

Chronic estrogenic drug treatment increases preproenkephalin mRNA levels in the rat striatum and nucleus accumbens

Saux, M. L., & Paolo, T. D. (2004) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2004.08.002 · Cited by 35

The effects of the selective estrogen receptor modulators, methyl‐piperidino‐pyrazole (MPP), and raloxifene in normal and cancerous endometrial cell lines and in the murine uterus

Davis, A., Ellersieck, M. R., Grimm, K. M., & Rosenfeld, C. S. (2006) · Molecular Reproduction and Development · doi:10.1002/mrd.20520 · Cited by 35

Activation of a Gq-coupled membrane estrogen receptor rapidly attenuates α2-adrenoceptor-induced antinociception via an ERK I/II-dependent, non-genomic mechanism in the female rat

Nag, S., & Mokha, S. S. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.02.040 · Cited by 34

Sepsis Strategies in Development

LaRosa, S. P., & Opal, S. M. (2008) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2008.06.007 · Cited by 34

The selective estrogen receptor-β agonist biochanin A shows vasculoprotective effects without uterotrophic activity

Schrepfer, S., Deuse, T., Münzel, T. F., Schäfer, H., Braendle, W. L., & Reichenspurner, H. C. (2006) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000185941.63497.10 · Cited by 34

Estrogen receptor β-subtype selective tetrahydrofluorenones: Use of a fused pyrazole as a phenol bioisostere

Wilkening, R. R., Ratcliffe, R. W., Fried, A. K., Meng, D., Sun, W., Colwell, L., Lambert, S., Greenlee, M. L., Nilsson, S., Thorsell, A. G., et al. (2006) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2006.05.036 · Cited by 34

A Silver(I)‐Estrogen Nanocluster: GSH Sensitivity and Targeting Suppression on HepG2 Cell

Shen, D., Wu, S., Wang, R., Zhang, Q., Ren, Z., Liu, H. S., Guo, H., & Gao, G. (2016) · Small · doi:10.1002/smll.201601936 · Cited by 33

Estrogen treatment prevents gray matter atrophy in experimental autoimmune encephalomyelitis

MacKenzie‐Graham, A. J., Rinek, G. A., Avedisian, A. A., Morales, L. B. J., Umeda, E. A., Boulat, B., Jacobs, R. E., Toga, A. W., & Voskuhl, R. R. (2012) · Journal of Neuroscience Research · doi:10.1002/jnr.23019 · Cited by 33

Steroid Receptors in the Ovary and Uterus

Couse, J. F., Hewitt, S. C., & Korach, K. S. (2006) · Elsevier eBooks · doi:10.1016/b978-012515400-0/50020-8 · Cited by 33

Estrogen receptor α-mediated events promote sex-specific diabetic glomerular hypertrophy

Lovegrove, A. S., Sun, J., Gould, K. A., Lubahn, D. B., Korach, K. S., & Lane, P. H. (2004) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00414.2003 · Cited by 33

Effects of estrogens and progesterone on the synaptic organization of the hypothalamic ventromedial nucleus

Sá, S. I., Lukoyanova, E. A., & Madeira, M. D. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.04.066 · Cited by 32

Estrogenic control of thermoregulation in ERαKO and ERβKO mice

Opas, E. E., Gentile, M. A., Kimmel, D. B., Rodan, G. A., & Schmidt, A. (2005) · Maturitas · doi:10.1016/j.maturitas.2005.04.006 · Cited by 32

Estrogen Receptor-Selective Agonists Modulate Learning in Female Rats in a Dose- and Task-Specific Manner

Pisani, S. L., Neese, S. L., Katzenellenbogen, J. A., Schantz, S. L., & Korol, D. L. (2015) · Endocrinology · doi:10.1210/en.2015-1616 · Cited by 31

The Utility of Estrogen Receptor and Progesterone Receptor Immunohistochemistry in the Distinction of Metastatic Breast Carcinoma From Other Tumors in the Liver

Nash, J. W., Morrison, C., & Frankel, W. L. (2003) · Archives of Pathology & Laboratory Medicine · doi:10.5858/2003-127-1591-tuoera · Cited by 31

Transcriptional activity and biological effects of mammalian estrogen receptor ligands on three hepatic estrogen receptors in Mozambique tilapia

Davis, L. K., Katsu, Y., Iguchi, T., Lerner, D. T., Hirano, T., & Grau, E. G. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.05.009 · Cited by 31

25 years of ERβ: a personal journey

Warner, M. N., Fan, X., Ström, A., Wu, W., & Gustafsson, J.-Α. (2021) · Journal of Molecular Endocrinology · doi:10.1530/jme-21-0121 · Cited by 30

Estrogen Alleviates Acetic Acid-Induced Gastric or Colonic Damage via Both ERα- and ERβ-Mediated and Direct Antioxidant Mechanisms in Rats

Kumral, Z. N. Ö., Memi, G., Ercan, F., & Yeğen, B. Ç. (2013) · Inflammation · doi:10.1007/s10753-013-9786-9 · Cited by 30

Developmental effects of perinatal exposure to PBDE and PCB on gene expression in sexually dimorphic rat brain regions and female sexual behavior

Faass, O., Ceccatelli, R., Schlumpf, M., & LICHTENSTEIGER, W. (2013) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2013.04.008 · Cited by 30

MicroRNAs and their role in gynecological tumors

Torres, A., Torres, K., Maciejewski, R., & Harvey, W. H. (2010) · Medicinal Research Reviews · doi:10.1002/med.20205 · Cited by 32

Effects of estrogen receptor alpha- and beta-selective substances in the metaphysis of the tibia and on serum parameters of bone and fat tissue metabolism of ovariectomized rats

Seidlová‐Wuttke, D., Prelle, K., Fritzemeier, K., & Wuttke, W. (2008) · Bone · doi:10.1016/j.bone.2008.07.237 · Cited by 30

Progestin receptor expression in the developing rat brain depends upon activation of estrogen receptor α and not estrogen receptor β

Chung, W. C. J., Pak, T. R., Weiser, M. J., Hinds, L. R., Andersen, M. E., & Handa, R. J. (2006) · Brain Research · doi:10.1016/j.brainres.2006.01.109 · Cited by 29

Development of a mouse model of mammary gland versus uterus tissue selectivity using estrogen- and progesterone-regulated gene markers

Crabtree, J. S., Zhang, X., Peano, B. J., Zhang, Z., Winneker, R. C., & Harris, H. A. (2006) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.06.017 · Cited by 29

Estradiol Attenuates Neuroprotective Benefits of Isoflurane Preconditioning in Ischemic Mouse Brain

Wang, L., Kitano, H., Hurn, P. D., & Murphy, S. J. (2008) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2008.70 · Cited by 29

Tools to evaluate estrogenic potency of dietary phytoestrogens:A consensus paper from the EU Thematic Network “Phytohealth” (QLKI-2002-2453)

Saarinen, N., Bingham, C., Lorenzetti, S., Mortensen, A., Mäkelä, S., Penttinen, P. E., Sørensen, I. K., Valsta, L. M., Virgili, F., Vollmer, G., et al. (2006) · Genes & Nutrition · doi:10.1007/bf02829964 · Cited by 29

Selective estrogen receptor α activation disrupts sex organ differentiation and induces expression of vitellogenin II and very low-density apolipoprotein II in Japanese quail embryos

Mattsson, A., Olsson, J., & Brunström, B. (2008) · Reproduction · doi:10.1530/rep-08-0100 · Cited by 29

Estrogen receptor β as a therapeutic target for promoting neurogenesis and preventing neurodegeneration

Zhao, L., & Brinton, R. D. (2005) · Drug Development Research · doi:10.1002/ddr.20049 · Cited by 29

Estrogen Receptors: Their Actions and Functional Roles in Health and Disease

Nilsson, S. V., & Gustafsson, J.-Α. (2010) · Springer eBooks · doi:10.1007/978-90-481-3303-1_5 · Cited by 31

Reproductive experience modifies the effects of estrogen receptor alpha activity on anxiety-like behavior and corticotropin releasing hormone mRNA expression

Byrnes, E. M., Casey, K. M., & Bridges, R. S. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.10.001 · Cited by 28

Estrogen Receptor β: Expression Profile and Possible Anti-Inflammatory Role in Disease

Catley, M. C., Birrell, M. A., Hardaker, E. L., Alba, J. D., Farrow, S. N., Haj‐Yahia, S., & Belvisi, M. G. (2008) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.136275 · Cited by 28

17β-Estradiol's salutary effects on splenic dendritic cell functions following trauma–hemorrhage are mediated via estrogen receptor-α

Kawasaki, T., Choudhry, M. A., Suzuki, T., Schwacha, M. G., Bland, K. I., & Chaudry, I. H. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2007.06.148 · Cited by 28

Oral Contraceptives and Skin Cancer

Leslie, K. K., & Espey, E. L. (2005) · American Journal of Clinical Dermatology · doi:10.2165/00128071-200506060-00002 · Cited by 28

Estrogen receptor β selective nonsteroidal estrogens: seeking clinical indications

Mohler, M. L., Narayanan, R., Coss, C. C., Hu, K., He, Y., Wu, Z., Hong, S., Hwang, D., Miller, D. D., & Dalton, J. T. (2010) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543771003657164 · Cited by 28

Effect of Oestrogen Receptor Alpha and Beta Agonists on Brain N‐Methyl‐ d ‐Aspartate Receptors

Morissette, M., Saux, M. L., & Paolo, T. D. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01754.x · Cited by 27

Role of estrogen receptor α and β in the induction of progesterone receptors in hypothalamic ventromedial neurons

Sá, S. I., Pereira, P. A., Malikov, V., & Madeira, M. D. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.02.023 · Cited by 27

Regulation of bone growth via ligand-specific activation of estrogen receptor alpha

Iravani, M., Lagerquist, M. K., Ohlsson, C., & Savendahl, L. S. (2016) · Journal of Endocrinology · doi:10.1530/joe-16-0263 · Cited by 27

Response-Specific and Ligand Dose-Dependent Modulation of Estrogen Receptor (ER) α Activity by ERβ in the Uterus

Frasor, J. M., Barnett, D., Danes, J. M., Hess, R., Parlow, A. F., & Katzenellenbogen, B. S. (2003) · Endocrinology · doi:10.1210/en.2002-0143 · Cited by 232

Dissecting Physiological Roles of Estrogen Receptor α and β with Potent Selective Ligands from Structure-Based Design

Hillisch, A., Peters, O., Kosemund, D., Müller, G. A., Walter, A., Schneider, B., Reddersen, G., Elger, W. A. G., & Fritzemeier, K. (2004) · Molecular Endocrinology · doi:10.1210/me.2004-0050 · Cited by 171

Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression

Harrington, W. R., Sheng, S., Barnett, D., Petz, L. N., Katzenellenbogen, J. A., & Katzenellenbogen, B. S. (2003) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(03)00255-7 · Cited by 301

Die Wirkung von selektiven Östrogenrezeptor [alpha] und [beta]-Agonisten auf Ovar und Uterus am Nagetier

Siebel, P., & Hegele‐Hartung, C. (2005) · RWTH Publications (RWTH Aachen)

Effects of selective estrogen receptor agonists on estrogen receptor expression in the uterus of ovariectomized rats

Blesson, C. S., Masironi, B., & Sahlin, L. (2012) · Open Journal of Molecular and Integrative Physiology · doi:10.4236/ojmip.2012.22006 · Cited by 6