Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity

FGF-21 as a novel metabolic regulator

Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23606 · Cited by 2,125

Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

Inagaki, T., Dutchak, P., Zhao, G., Ding, X., Gautron, L., Parameswara, V., Li, Y., Goetz, R., Mohammadi, M., Esser, V., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.05.003 · Cited by 1,504

Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States

Badman, M. K., Pissios, P., Kennedy, A. R., Koukos, G., Flier, J. S., & Maratos-Flier, E. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.05.002 · Cited by 1,495

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

Xu, J., Lloyd, D. J., Hale, C., Stanislaus, S., Chen, M., Sivits, G., Vonderfecht, S., Hecht, R., Li, Y.-S., Lindberg, R. A., et al. (2009) · Diabetes · doi:10.2337/db08-0392 · Cited by 1,151

Fibroblast Growth Factor 21 Corrects Obesity in Mice

Coskun, T., Bina, H. A., Schneider, M. A., Dunbar, J. D., Hu, C. C., Chen, Y., Moller, D. E., & Kharitonenkov, A. (2008) · Endocrinology · doi:10.1210/en.2008-0816 · Cited by 1,031

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

Zhang, X., Yeung, D. C. Y., Karpisek, M., Stejskal, D., Zhou, Z.-G., Liu, F., Wong, R. L. C., Chow, W.-S., Tso, A. W. K., Lam, K. S. L., et al. (2008) · Diabetes · doi:10.2337/db07-1476 · Cited by 908

The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21

Kharitonenkov, A., Wroblewski, V. J., Koester, A., Chen, Y.-F., Clutinger, C. K., Tigno, X. T., Hansen, B. C., Shanafelt, A. B., & Etgen, G. J. (2007) · Endocrinology · doi:10.1210/en.2006-1168 · Cited by 738

βKlotho is required for metabolic activity of fibroblast growth factor 21

Ogawa, Y., Kurosu, H., Yamamoto, M., Nandi, A., Rosenblatt, K. P., Goetz, R., Eliseenkova, A. V., Mohammadi, M., & Kuro-o, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701600104 · Cited by 617

Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

Viollet, B., Foretz, M., Guigas, B., Horman, S., Dentin, R., Bertrand, L., Hue, L., & Andréelli, F. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.108506 · Cited by 543

Fibroblast Growth Factor-21 Improves Pancreatic β-Cell Function and Survival by Activation of Extracellular Signal–Regulated Kinase 1/2 and Akt Signaling Pathways

Wente, W., Efanov, A. M., Brenner, M. B., Kharitonenkov, A., Koster, A. M., Sandusky, G. E., Sewing, S., Treinies, I., Zitzer, H., & Gromada, J. (2006) · Diabetes · doi:10.2337/db05-1435 · Cited by 497

Effects of omega-3 fatty acids and pioglitazone combination on insulin resistance through fibroblast growth factor 21 in type 2 diabetes mellitus

Eissa, L. A., Abdel‐Rahman, N., & Eraky, S. M. (2015) · Egyptian Journal of Basic and Applied Sciences · doi:10.1016/j.ejbas.2015.01.002 · Cited by 11

Pharmacologic stimulation of central GLP-1 receptors has opposite effects on the alterations of plasma FGF21 levels induced by feeding and fasting

Nonogaki, K., Kaji, T., Yamazaki, T., & Murakami, M. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.12.011 · Cited by 11

Role of Omega-3-Fatty Acids in the Management of Diabetes and Associated Complications

Behl, T., Grover, M., Shah, K., Makkar, R., Kaur, L., Sharma, S., & Gupta, J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813822-9.00012-6 · Cited by 11

Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice

Krumm, C. S., Xu, X., Bare, C. J., Holman, C. D., Kersten, S., Dow, L. E., Lee, A.-H., & Cohen, D. E. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100815 · Cited by 11

Investigation of Metabolic and Inflammatory Disorder in the Aging FGF21 Knockout Mouse

Cai, L., Li, X., Wang, Y., Chen, Y., Zhu, X., Zuo, Z., Si-Ma, Y.-Q., Lin, Y., Li, X., & Huang, X. (2024) · Inflammation · doi:10.1007/s10753-024-02032-3 · Cited by 10

Novel Approaches to the Management of Diabetes Mellitus in Patients with Coronary Artery Disease

Oikonomou, E. K., Xenou, M., Zakynthinos, G. Ε., Tsaplaris, P., Lampsas, S., Bletsa, E., Gialamas, I., Kalogeras, K. I., Goliopoulou, A., Gounaridi, M. I., et al. (2023) · Current Pharmaceutical Design · doi:10.2174/1381612829666230703161058 · Cited by 11

Research progress on the role of FGF21 in insulin resistance

Zhang, H., Zhu, R., Sun, Q., & Du, L. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1619462 · Cited by 10

A study of the circulating fibroblast growth factor 21 as a novel noninvasive biomarker of hepatic injury in genotype-4 chronic hepatitis C: Egyptian patients and their response to direct-acting antiviral agents

Sagheer, G. E., Ahmad, A., Abd-ElFattah, A., Saad, Z. M., & Hamdi, L. (2018) · Clinical and Experimental Gastroenterology · doi:10.2147/ceg.s173484 · Cited by 9

The Diagnostic Role of FGF 21 in Endometrial Cancer and Other Pathologies of the Uterine Corpus

Jagodzińska, A., Chudecka-Glaz, A. M., Michalczyk, K., Pius‐Sadowska, E., Wieder-Huszla, S., Jurczak, A., & Machaliński, B. (2023) · Diagnostics · doi:10.3390/diagnostics13030399 · Cited by 9

Lost in Translation

Wasserman, D. H., Ayala, J. E., & McGuinness, O. P. (2009) · Diabetes · doi:10.2337/db09-0537 · Cited by 9

Design of a Dual Agonist of Exendin-4 and FGF21 as a Potential Treatment for Type 2 Diabetes Mellitus and Obesity

Zhang, C., Gao, G., Li, Y., Ying, J., Li, J., & Hu, S. (2023) · Iranian journal of pharmaceutical research · doi:10.5812/ijpr-131015 · Cited by 8

Effects and Safety of FGF21 Analogs on Glycemic Parameters, Lipid Profiles, and Adiponectin in Overweight and Obese Adults: A Meta‐Analysis of Randomized Controlled Trials

Nie, Z., Xu, J., Liu, Y., Cao, Q., Qiu, X., Su, Y., & Han, S. (2025) · International Journal of Endocrinology · doi:10.1155/ije/9943228 · Cited by 8

Pancreatic Islet Cell Hormones: Secretion, Function, and Diabetes Therapy

Ma, J., Mao, L., Yang, L., Xie, Q., Fan, R., Lu, X., Huang, X., Tong, N., & Duan, Z. (2025) · MedComm · doi:10.1002/mco2.70359 · Cited by 11

Regulation of Endogenous Glucose Production in Glucose Transporter 4 Over-Expressing Mice

Berglund, E. D., Li, C. Y., Ayala, J. E., McGuinness, O. P., & Wasserman, D. H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052355 · Cited by 8

Studying sex differences in responses to fibroblast growth factor 21 administration in obese mice consuming a sweet-fat diet

Бажан, Н. М., Jakovleva, T., Kazantseva, A. Y., Костина, Н. Е., Orlov, P. E., Balybina, N., Baranov, K. O., & En, M. (2023) · Vavilov Journal of Genetics and Breeding · doi:10.18699/vjgb-23-40 · Cited by 9

Functions of FGF21 and its role in cardiac hypertrophy

Chen, L., Gao, M., Ong, S., & Gong, G. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.03.007 · Cited by 7

Unveiling the Impact of BMP9 in Liver Diseases: Insights into Pathogenesis and Therapeutic Potential

Chen, H., Li, Y.-Y., Nio, K., & Tang, H. (2024) · Biomolecules · doi:10.3390/biom14081013 · Cited by 8

Peroxisome Proliferator-Activated Receptor α Has a Protective Effect on Fatty Liver Caused by Excessive Sucrose Intake

Yamazaki, T., & Ihato, M. (2022) · Biomedicines · doi:10.3390/biomedicines10092199 · Cited by 7

Liver but not adipose tissue is responsive to the pattern of enteral feeding

Otero, Y. F., Lundblad, T. M., Ford, E. A., House, L. M., & McGuinness, O. P. (2014) · Physiological Reports · doi:10.1002/phy2.250 · Cited by 7

Sexual dimorphism of MASLD-driven bone loss

Goldscheitter, G., Seneshaw, M., Mirshahi, F., Buettmann, E. G., Genetos, D. C., Sanyal, A. J., & Donahue, H. J. (2025) · Scientific Reports · doi:10.1038/s41598-025-08693-w · Cited by 6

Effects of central FGF21 infusion on the glucose homeostasis in rats (brain–pancreas axis)

Tanbek, K., Yılmaz, Ü., Gül, M., Koç, A., & Sandal, S. (2023) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2023.2166964 · Cited by 6

Induction of fibroblast growth factor 21 does not require activation of the hepatic X-box binding protein 1 in mice

Olivares, S., & Henkel, A. S. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.09.006 · Cited by 6

Fibroblast Growth Factor 21: Mechanisms, Therapeutic Potential, and Clinical Translation in Metabolic Dysfunction

Rama, K., Jahagirdar, V., & Sanyal, A. J. (2026) · Drug Design Development and Therapy · doi:10.2147/dddt.s560034 · Cited by 6

The Association Between FGF21 and Diabetic Erectile Dysfunction: Evidence from Clinical and Animal Studies

Song, Y., Zhang, Y., Lyu, X., Gu, Y., Zhang, G., Liu, P., Zheng, Y., Guo, Z., Zhang, Y., & Hou, H. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.874796 · Cited by 5

Treatment with FGFR2-IIIc monoclonal antibody suppresses weight gain and adiposity in KKAy mice

Nonogaki, K., Kaji, T., Yamazaki, T., & Murakami, M. (2016) · Nutrition and Diabetes · doi:10.1038/nutd.2016.41 · Cited by 5

Adherence to low carbohydrate diets and non-alcoholic fatty liver disease: a case control study

Yaghoubi, F., Darand, M., Vasmehjani, A. A., Darabi, Z., Talenezhad, N., Mirzavandi, F., & Hosseinzadeh, M. (2022) · BMC Nutrition · doi:10.1186/s40795-022-00625-5 · Cited by 4

Network signatures link hepatic effects of anti-diabetic interventions with systemic disease parameters

Kelder, T., Verschuren, L., van Ommen, B., van Gool, A. J., & Radonjić, M. (2014) · BMC Systems Biology · doi:10.1186/s12918-014-0108-0 · Cited by 6

The role of the glucagon‐FGF21 axis in improving beta cell function during glucose intolerance and SGLT2 inhibition

Moreno-Lopez, M., Louvet, I., Delalleau, N., Acosta-Montalvo, A., Thévenet, J., Pasquetti, G., Gmyr, V., Kerr-Conte, J. A., Pattou, F. N., Bonner, C., et al. (2024) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16089 · Cited by 4

Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside

Huang, Y., Liu, B., Hu, C., & Lu, Y. (2025) · Protein & Cell · doi:10.1093/procel/pwaf027 · Cited by 4

A Novel Recombinant Human FGF21 Analog with High Glycosylation Has a Prolonged Half-Life and Affects Glycemic and Body Weight Control

Du, P., Wang, T., Wang, R., Liu, S., Wang, H., & Yin, H. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26062672 · Cited by 4

The association of FGF-21 with the risk of newly diagnosed type-2 diabetes mellitus: a cross-sectional study in Southern China

You, L., Hong, X., Wu, H., Liang, D., Li, F., Zheng, D., Zhang, X., Liu, D., Chen, Q., Yan, L., et al. (2023) · BMC Endocrine Disorders · doi:10.1186/s12902-023-01426-y · Cited by 4

The hepatokine FGF21 stopped lipogenesis and reduced testosterone production in mLTC-1 Leydig Cell Line.

Bourdon, G., Chevaleyre, C., Estienne, A., Péchoux, C., Bourgeais, J., Hérault, O., Ba, M., Ramé, C., Dupont, J., Ducluzeau, P., et al. (2024) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2024.112350 · Cited by 2

Amelioration of palmitate-induced metabolic dysfunction in L6 muscle cells expressing low levels of receptor-interacting protein 140

Constantinescu, S., & Turcotte, L. P. (2015) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2015-0020 · Cited by 4

Fibroblast growth factor 21 and its influence on metabolic processes in the human body

Proshchai, G. A., Ворохобина, Н. В., Zagarskikh, E. Y., Александрович, П. С., & Partsernyak, A. S. (2018) · Vestnik of Saint Petersburg University Medicine · doi:10.21638/11701/spbu11.2018.104 · Cited by 4

An fgf21-like gene from swamp eel (Monopterus albus): Recombinant expression and its potential roles in glucose and lipid homeostasis

Zheng, S., Wu, J., Xiang, S., Zang, Y., Kong, D., Wei, X., Sun, W., & Li, W. (2022) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2022.111170 · Cited by 4

Bibliometric analysis of fibroblast growth factor 21 research over the period 2000 to 2021

She, Q.-Y., Li, L., Liu, M.-H., Tan, R.-Y., Zhong, Y.-W., Bao, J., & Xie, J.-D. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1011008 · Cited by 9

Serum Level of Fibroblast Growth Factor 21 in Type 2 Diabetic Patients with and without Metabolic Syndrome

Shafaei, A., Khoshnia, M., & Marjani, A. (2015) · Journal of Medical Sciences(Faisalabad) · doi:10.3923/jms.2015.80.86 · Cited by 4

Therapeutic potential of FGF21 in diabetes

Davis, D., Garg, C., & Lahiri, S. (2017) · Journal of Medicinal Plants Studies · Cited by 4

Impact of moderate dietary protein restriction on glucose homeostasis in a model of estrogen deficiency

Fournier, C., Karagounis, L. G., Sacco, S. M., Horcajada, M.-N., Decaens, T., Offord, E., Bouzakri, K., & Ammann, P. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.108952 · Cited by 3

Liver, but Not Muscle, Has an Entrainable Metabolic Memory

Chen, S., Otero, Y. F., Mulligan, K. X., Lundblad, T. M., Williams, P. E., & McGuinness, O. P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086164 · Cited by 3

Peeling back the layers of the glucose clamp

Ayala, J. E., Lantier, L., McGuinness, O. P., & Wasserman, D. H. (2022) · Nature Metabolism · doi:10.1038/s42255-022-00573-1 · Cited by 3

Nuclear Receptors in Energy Metabolism

Walth-Hummel, A. A., Herzig, S., & Rohm, M. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-11836-4_4 · Cited by 4

Hepatic lipogenesis marked by GCKR ‐modulated triglycerides increases serum FGF21 in children/teens with obesity

Maffeis, C., Morandi, A., Zusi, C., Olivieri, F., Fornari, E., Cavarzere, P., Piona, C. A., Corradi, M., Emiliani, F., Ros, A. D., et al. (2024) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16081 · Cited by 3

Role of Fibroblast Growth Factor 21 in Biology of Glucagon

Berglund, E. D., & Unger, R. H. (2013) · Diabetes · doi:10.2337/db12-1840 · Cited by 3

Fibroblast Growth Factor 21 is a Regulator of Energy Metabolism in the Liver and Adipose Tissue

Matikainen, N. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-407869-7.00039-8 · Cited by 3

A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressurePreprint

Frayling, T. M., Beaumont, R. N., Jones, S. E., Yaghootkar, H., Tuke, M. A., Ruth, K. S., Casanova, F., West, B., Locke, J. M., Sharp, S. A., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/214700 · Cited by 3

Advances of pharmacological therapies in lipodystrophy syndromes: current evidence and future directions

Besci, Ö., Güler, M. Ç., Foss‐Freitas, M. C., & Oral, E. A. (2025) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2025.2574318 · Cited by 2

Fibroblast Growth Factor 21 as a Regulator of Energy Metabolism in the Liver and Adipose Tissue

Matikainen, N., & Söderlund, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816093-0.00013-6 · Cited by 2

FGF21 Improves Glycolipid Metabolism in Rainbow Trout ( Oncorhynchus mykiss ) Fed a High-Carbohydrate Diet by Inhibiting Inflammatory Responses and Activating Autophagy

Yu, H., Zhong, D., Li, S., Mo, H., Zhang, Z., Gao, J., Ren, X., Yu, J., Geng, S., Wang, Y., et al. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c06768 · Cited by 2

Novel FGF21 analogues through structure-based optimization for therapeutic development

Guo, Y., Bao, Y., Chen, Z., Rao, Z., Luo, Y., Ye, S., & Liu, S. (2024) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2024227 · Cited by 2

Glycaemic Control and Protection of the Vasculature from Glucose Toxicity

Ding, H., & Chris, R. B. (2011) · InTech eBooks · doi:10.5772/24862 · Cited by 2

The impact of LDLR function on fibroblast growth factor 21 levels

Besseling, J., Ong, K. L., Huijgen, R., Rye, K., Hovingh, G. K., Hutten, B. A., & Lambert, G. C. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.05.032 · Cited by 2

Fibroblast growth factor-21 may be a potential novel drug for preventing the development of traumatic TMJ bony ankylosis

Liang, S.-X., & Yan, Y. (2013) · Journal of Medical Hypotheses and Ideas · doi:10.1016/j.jmhi.2013.07.002 · Cited by 2

Glucose and lipopolysaccharide differentially regulate fibroblast growth factor 21 in healthy male human volunteers – A prospective cross‐over trial

Pohlhammer, J., Heinzl, M. W., Klammer, C., Feldbauer, R., Rosenberger, K., Resl, M., Wagner, T., Obendorf, F., Egger-Salmhofer, M., Dieplinger, B., et al. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17614 · Cited by 1

Fibroblast Growth Factor 21 as a Novel Metabolic Regulator

Micanovic, R., Dunbar, J. D., & Kharitonenkov, A. (2011) · Wiley eBooks · doi:10.1002/9780470910016.ch14 · Cited by 2

Endocrinology and metabolism

Li, X. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15793-6.00003-2 · Cited by 2

Structure and modification

Li, X. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15793-6.00004-4 · Cited by 2

Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model

Gorton, M. W., Goodarzi, P., Lei, X., Anderson, M. C., Habibi, M., Wilson, N. F., & Pezeshki, A. (2025) · Nutrients · doi:10.3390/nu17101675 · Cited by 1

α1-acid Glycoprotein mitigates MASLD progression by modulating liver and adipose tissue function

Nishinoiri, A., Tokumaru, K., Kanazawa, G., Shintani, Y., Yoshitake, T., Yamamoto, T., Fukuta, S., Nishimura, A., Nishida, M., Takeo, T., et al. (2026) · Endocrinology · doi:10.1210/endocr/bqag009

STUDIES ON THE REGULATION OF FGF21 GENE EXPRESSION BY (R)-α-LIPOIC ACID: MECHANISTIC INSIGHT INTO THE LIPID LOWERING PROPERTIES OF A DITHIOL DIETARY MOLECULE

Yi, X. (2013) · Lincoln (University of Nebraska) · Cited by 1

Comparison of Swarm Optimization and Genetic Algorithm for Mobile Robot Navigation

Ćurković, P., Jerbić, B., & Stipanĉić, T. (2010) · InTech eBooks · doi:10.5772/8601 · Cited by 1

Circulating leukocyte cell-derived chemotaxin 2 and fibroblast growth factor 21 are negatively associated with cardiorespiratory fitness in healthy volunteers

Malaikah, S., Willis, S. A., Henson, J. J., Sargeant, J. A., Yates, T. E., Thackray, A. E., Goltz, F. R., Roberts, M. J., Bernard-Deshong, D., Aithal, G. P., et al. (2023) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2022-0445 · Cited by 1

Differences in metabolic improvement after metabolic surgery are linked to the gut microbiota in non-obese diabetic rats

Luo, X., Tan, C. N., Fang, T., Xu, C.-Y., Zheng, Z., Pang, Q., He, X.-A., Cao, J., & Duan, J. (2023) · World Journal of Gastrointestinal Surgery · doi:10.4240/wjgs.v15.i7.1304 · Cited by 1

Growth factors reviews

Li, X. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15793-6.00001-9 · Cited by 1

Glucosamine induces hepatic FGF21 expression by activating the Akt/mTOR/p70S6K axis and driving PGC-1α activity

Liu, S.-Y., Chen, L.-K., Li, P.-H., Wu, G.-L., Wu, T.-C., Yu, Y., Lin, H., & Juan, C. (2025) · Scientific Reports · doi:10.1038/s41598-025-96249-3 · Cited by 1

Pathophysiology and Pharmacology of FGFs

Li, X. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-816142-5.00004-7 · Cited by 1

The Metabolic Effects of FGF21: From Physiology to Pharmacology

Song, P. (2020) · JoLS Journal of Life Sciences · doi:10.5352/jls.2020.30.7.640 · Cited by 1

FGF21 Attenuates Neurodegeneration though Modulating Neuroinflammation and Oxidant-stressPreprint

Kang, K., Xu, P., Wang, M., Chunyu, J., Sun, X., Ren, G., Xiao, W. L., & li, D. (2020) · doi:10.21203/rs.2.17629/v2 · Cited by 2

The role of metabolic hormone Fibroblast Growth Factor 21 (FGF21) in mammalian hibernation using transgenic ground squirrels

Nelson, B. T. (2012) · University of Minnesota Digital Conservancy (University of Minnesota)

LY2405310 : un analogue du FGF21 avec une efficacité métabolique partielle

Dubois‐Laforgue, D. (2014) · Médecine des Maladies Métaboliques · doi:10.1016/s1957-2557(14)70753-9

IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY

Nelson, B. T. (2012)

Mediators and markers of mammalian lifespan extension: Proteomic, proliferative and hormonal adaptations in mouse models of extended lifespan

Thompson, A. C. S. (2014) · ProQuest Demo Repository

CLINICAL ADVANCES IN LIVER, PANCREAS, AND BILIARY TRACT Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

Dushay, J. R., Chui, P. C., Gopalakrishnan, G. S., Crawley, M. B., Fisher, F. M., & Badman, M. K. (2010)

The Role of Histone Deacetylases in Glucose Metabolism: a Mini- Review

Liu, F. (2015) · International Journal of Endocrinology and Metabolic Disorders · doi:10.16966/2380-548x.113

Fibroblast Growth Factor 21 is a Novel Protein Sensor in Pregnancy

Sutton, E. F. (2017) · doi:10.31390/gradschool_dissertations.4263

KLOTHO PROTEINS KLO-1 AND KLO-2 INTERACT WITH DAF-2/DAF-16 PATHWAY TO REGULATE ENERGY METABOLISM, STRESS RESISTANCE AND AGEING

Buj, D. (2019) · University of Huddersfield Repository (University of Huddersfield)

Exercise habits and ageing health : exploring the associations of FGF21 and lung microbiome in glycaemic regulation, bone health, arterial stiffness and respiratory health

Lee, S. Y. (2020) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/136835

Molecular description of fibroblast growth factor and mechanisms by which fibroblast growth factor-21 mediating biological actions and acting as a biologic biomarker of cardiovascular diseases

Melaku, L. S., & Debela, N. (2020) · Indian Journal of Health Sciences and Biomedical Research (KLEU) · doi:10.4103/kleuhsj.kleuhsj_92_20

Uninephrectomy and class II PI3K-C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice

Alliouachene, S., Kieswich, J. E., Bilanges, B., McCafferty, K., Thiemermann, C., Vanhaesebroeck, B., & Yaqoob, M. (2020) · American Journal of Transplantation · doi:10.1111/ajt.16470

Faculty Opinions recommendation of Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones.

Means, A. R. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.13865958.15303059

The developing link of metabolic growth factors in insulin resistance

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Toxicokinetics of recombinant human fibroblast growth factor 21 for injection in cynomolgus monkey for three monthsPreprint

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