Roles of Chemokine Ligand-2 (CXCL2) and Neutrophils in Influencing Endothelial Cell Function and Inflammation of Human Adipose Tissue

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760

Monocyte and macrophage heterogeneity

Gordon, S., & Taylor, P. R. (2005) · Nature Reviews Immunology · doi:10.1038/nri1733 · Cited by 5,190

Neutrophils in the activation and regulation of innate and adaptive immunity

Mantovani, A., Cassatella, M. A., Costantini, C., & Jaillon, S. (2011) · Nature reviews. Immunology · doi:10.1038/nri3024 · Cited by 3,159

Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome

Wajchenberg, B. L. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.6.0415 · Cited by 2,961

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

Kanda, H. (2006) · Journal of Clinical Investigation · doi:10.1172/jci26498 · Cited by 2,682

Adipokines: inflammation and the pleiotropic role of white adipose tissue

Trayhurn, P., & Wood, I. S. (2004) · British Journal of Nutrition · doi:10.1079/bjn20041213 · Cited by 2,210

Four faces of cellular senescence

Rodier, F., & Campisi, J. (2011) · Journal of Cell Biology · doi:10.1083/jcb.201009094 · Cited by 2,070

Inflammatory networks during cellular senescence: causes and consequences.

Freund, A., Orjalo, A. V., Desprez, P.-Y., & Campisi, J. (2010) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2010.03.003 · Cited by 1,354

PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

Bouhlel, M. A., Derudas, B., Rigamonti, E., Dièvart, R., Brozek, J., Haulon, S., Zawadzki, C., Jude, B., Torpier, G., Marx, N., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.06.010 · Cited by 1,325

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

McDonald, B., Pittman, K., Menezes, G. B., Hirota, S. A., Slaba, I., Waterhouse, C. C. M., Beck, P. L., Muruve, D. A., & Kubes, P. (2010) · Science · doi:10.1126/science.1195491 · Cited by 1,210

Roles for chemokines in liver disease

Marra, F., & Tacke, F. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.06.043 · Cited by 829

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis.

Crewe, C., An, Y. A., & Scherer, P. E. (2017) · Journal of Clinical Investigation · doi:10.1172/jci88883 · Cited by 732

Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer

Zhang, Y., Chandra, V., Riquelme, E. M., Dutta, P., Quesada, P. R., Rakoski, A. I., Zoltan, M. A., Arora, N., Baydogan, S., Horne, W. T., et al. (2020) · The Journal of Experimental Medicine · doi:10.1084/jem.20190354 · Cited by 451

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

Musso, G., Cassader, M., & Gambino, R. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2015.3 · Cited by 424

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity

Dalmas, E., Toubal, A., Alzaid, F., Blazek, K., Eames, H. L., Lebozec, K., Pini, M., Hainault, I., Montastier, E., Denis, R. G. P., et al. (2015) · Nature Medicine · doi:10.1038/nm.3829 · Cited by 205

Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity

Pellegrinelli, V., Rouault, C., Rodríguez‐Cuenca, S., Albert, V., Edom‐Vovard, F., Vidal‐Puig, A., Clément, K., Butler-Browne, G. S., & Lacasa, D. (2015) · Diabetes · doi:10.2337/db14-0796 · Cited by 209

Parallels in Immunometabolic Adipose Tissue Dysfunction with Ageing and Obesity

Trim, W. V., Turner, J. E., & Thompson, D. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00169 · Cited by 178

Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes

Oral, E. A., Reilly, S. M., Gomez, A. V., Meral, R., Butz, L., Ajluni, N., Chenevert, T. L., Korytnaya, E., Neidert, A., HENCH, R. P., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.06.006 · Cited by 165

The noncoding and coding transcriptional landscape of the peripheral immune response in patients with COVID‐19

Tang, H., Gao, Y., Li, Z., Miao, Y., Huang, Z., Liu, X., Xie, L., Li, H., Wen, W., Zheng, Y., et al. (2020) · Clinical and Translational Medicine · doi:10.1002/ctm2.200 · Cited by 157

Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue

Caër, C., Rouault, C., Roy, T. L., Poitou, C., Aron‐Wisnewsky, J., Torcivia, A., Bichet, J.-C., Clément, K., Guerre-Millo, M., & André, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-02660-w · Cited by 165

Chemokines and Chemokine Receptors: Orchestrating Tumor Metastasization

Marcuzzi, E., Angioni, R., Molon, B., & Calì, B. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms20010096 · Cited by 162

The Human Milk Oligosaccharide 2′-Fucosyllactose Quenches Campylobacter jejuni–Induced Inflammation in Human Epithelial Cells HEp-2 and HT-29 and in Mouse Intestinal Mucosa

Yu, Z., Nanthakumar, N. N., & Newburg, D. S. (2016) · Journal of Nutrition · doi:10.3945/jn.116.230706 · Cited by 142

Innate Immune Cells in the Adipose Tissue in Health and Metabolic Disease

Michailidou, Z., Gomez-Salazar, M. A., & Alexaki, V. I. (2021) · Journal of Innate Immunity · doi:10.1159/000515117 · Cited by 143

Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice

Bijnen, M., Josefs, T., Cuijpers, I., Maalsen, C. J., van de Gaar, J., Vroomen, M., Wijnands, E., Rensen, S. S., Greve, J. W. M., Hofker, M. H., et al. (2018) · Gut · doi:10.1136/gutjnl-2016-313654 · Cited by 134

From chronic overnutrition to metaflammation and insulin resistance: adipose tissue and liver contributions

Caputo, T., Gilardi, F., & Desvergne, B. (2017) · FEBS Letters · doi:10.1002/1873-3468.12742 · Cited by 112

Regulation and functional roles of chemokines in liver diseases

Cao, S., Liu, M., Sehrawat, T. S., & Shah, V. H. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00444-2 · Cited by 106

Adipocytes, Innate Immunity and Obesity: A Mini-Review

Blaszczak, A. M., Jalilvand, A., & Hsueh, W. A. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.650768 · Cited by 109

Senescence-associated β-galactosidase in subcutaneous adipose tissue associates with altered glycaemic status and truncal fat in severe obesity

Rouault, C., Marcelin, G., Adriouch, S., Rose, C., Genser, L., Ambrosini, M., Bichet, J.-C., Zhang, Y., Marquet, F., Aron-Wisnewsky, J., et al. (2021) · Diabetologia · doi:10.1007/s00125-020-05307-0 · Cited by 95

Increased Basement Membrane Components in Adipose Tissue During Obesity: Links With TGFβ and Metabolic Phenotypes

Reggio, S., Rouault, C., Poitou, C., Bichet, J.-C., Prifti, E., Bouillot, J., Rizkalla, S. W., Lacasa, D., Tordjman, J., & Clément, K. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-4304 · Cited by 94

Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective

Ruebel, M. L., Cotter, M., Sims, C. R., Moutos, D. M., Badger, T. M., Cleves, M. A., Shankar, K., & Andres, A. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3524 · Cited by 91

The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice

Yu, H., Luo, H., Chang, L., Wang, S., Geng, X., Kang, L., Zhong, Y., Cao, Y., Wang, R., Yang, X., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2111896119 · Cited by 76

Macrophage development and activation involve coordinated intron retention in key inflammatory regulators

Green, I. D., Pinello, N., Song, R., Lee, Q., Halstead, J. M., Kwok, C., Wong, A. C. H., Nair, S. S., Clark, S. J., Roediger, B., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa435 · Cited by 75

Spotlight on the Mechanism of Action of Semaglutide

Papakonstantinou, I. P., Tsioufis, K. P., & Katsi, V. K. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46120872 · Cited by 89

Obesity-associated microbiomes instigate visceral adipose tissue inflammation by recruitment of distinct neutrophils

Shantaram, D., Hoyd, R., Blaszczak, A. M., Antwi, L., Jalilvand, A., Wright, V. P., Liu, J., Smith, A. J., Bradley, D. P., Lafuse, W. P., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-48935-5 · Cited by 75

Endothelial Cells From Visceral Adipose Tissue Disrupt Adipocyte Functions in a Three-Dimensional Setting: Partial Rescue by Angiopoietin-1

Pellegrinelli, V., Rouault, C., Veyrie, N., Clément, K., & Lacasa, D. (2013) · Diabetes · doi:10.2337/db13-0537 · Cited by 70

Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity

Weinstock, A., Silva, H. M., Moore, K. J., Schmidt, A. M., & Fisher, E. A. A. (2020) · Circulation Research · doi:10.1161/circresaha.120.316203 · Cited by 68

Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics

Brassington, K., Selemidis, S., Bozinovski, S., & Vlahos, R. (2022) · Clinical Science · doi:10.1042/cs20210835 · Cited by 72

Identification of key signaling pathways induced by SARS-CoV2 that underlie thrombosis and vascular injury in COVID-19 patients

Maxwell, A. J., Ding, J., You, Y., Dong, Z., Chehade, H., Alvero, A. B., Mor, Y., Drăghici, S., & Mor, G. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.4covr0920-552rr · Cited by 57

Transcriptome landscape of myeloid cells in human skin reveals diversity, rare populations and putative DC progenitors

Xue, D., Tabib, T., Morse, C., & Lafyatis, R. (2019) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2019.11.012 · Cited by 54

Crosstalk Between Mast Cells and Adipocytes in Physiologic and Pathologic Conditions

Komi, D. E. A., Shafaghat, F., & Christian, M. (2020) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-020-08785-7 · Cited by 56

Allometrically scaling tissue forces drive pathological foreign-body responses to implants via Rac2-activated myeloid cells

Padmanabhan, J., Chen, K., Sivaraj, D., Henn, D., Kuehlmann, B. A., Kussie, H. C., Zhao, E. T., Kahn, A., Bonham, C. A., Dohi, T., et al. (2023) · Nature Biomedical Engineering · doi:10.1038/s41551-023-01091-5 · Cited by 58

Conditioning solid tumor microenvironment through inflammatory chemokines and S100 family proteins

Nasser, M. W., Elbaz, M., Ahirwar, D. K., & Ganju, R. K. (2015) · Cancer Letters · doi:10.1016/j.canlet.2015.05.002 · Cited by 48

Exercise training attenuates neutrophil infiltration and elastase expression in adipose tissue of high-fat-diet-induced obese mice

Kawanishi, N., Niihara, H., Mizokami, T., Yada, K., & Suzuki, K. (2015) · Physiological Reports · doi:10.14814/phy2.12534 · Cited by 47

Physiological Changes and Pathological Pain Associated with Sedentary Lifestyle-Induced Body Systems Fat Accumulation and Their Modulation by Physical Exercise

Verdú, E., Homs, J., & Boadas‐Vaello, P. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182413333 · Cited by 57

Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance

Gilleron, J., Bouget, G., Ivanov, S., Méziat, C., Ceppo, F., Vergoni, B., Djedaini, M., Soprani, A., Dumas, K., Jacquel, A., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.11.083 · Cited by 47

Ginkgolide B Mediated Alleviation of Inflammatory Cascades and Altered Lipid Metabolism in HUVECs via Targeting PCSK-9 Expression and Functionality

Wang, G., Liu, Z., Li, M., Yu, L., Alvi, S. S., Ansari, I. A., & Khan, M. S. (2019) · BioMed Research International · doi:10.1155/2019/7284767 · Cited by 46

Adipose tissue immune cells in obesity, type 2 diabetes mellitus and cardiovascular diseases

Cinkajzlová, A., Mráz, M., & Haluzík, M. (2021) · Journal of Endocrinology · doi:10.1530/joe-21-0159 · Cited by 47

Multifaceted Breast Cancer: The Molecular Connection With Obesity

Feola, A., Ricci, S., Kouidhi, S., Rizzo, A., Penon, A., Formisano, P., Giordano, A., Carlo, A. D., & Domenico, M. D. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25475 · Cited by 46

Specialized Proresolving Mediators: Enhancing Nonalcoholic Steatohepatitis and Fibrosis Resolution

Musso, G., Gambino, R., Cassader, M., Paschetta, E., & Sircana, A. (2018) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2018.01.003 · Cited by 46

Grape seed procyanidin supplementation to rats fed a high-fat diet during pregnancy and lactation increases the body fat content and modulates the inflammatory response and the adipose tissue metabolism of the male offspring in youth

Bas-Prior, J. M. D., Crescenti, A., Arola‐Arnal, A., Oms‐Oliu, G., Arola, L., & Caimari, A. (2014) · International Journal of Obesity · doi:10.1038/ijo.2014.159 · Cited by 43

Impact of bariatric surgery on type 2 diabetes: contribution of inflammation and gut microbiome?

Debédat, J., Amouyal, C., Aron‐Wisnewsky, J., & Clément, K. (2019) · Seminars in Immunopathology · doi:10.1007/s00281-019-00738-3 · Cited by 45

Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence

Marthandan, S., Menzel, U., Priebe, S., Groth, M., Guthke, R., Platzer, M., Hemmerich, P., Kaether, C., & Diekmann, S. (2016) · Biological Research · doi:10.1186/s40659-016-0095-2 · Cited by 39

Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity

Yang, H. S., Graham, L. C., Reagan, A. M., Grabowska, W. A., Schott, W. H., & Howell, G. R. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1527-z · Cited by 41

Organogermanium suppresses cell death due to oxidative stress in normal human dermal fibroblasts

Takeda, T., Doiyama, S., Azumi, J., Shimada, Y., Tokuji, Y., Yamaguchi, H., Nagata, K., Sakamoto, N., Aso, H., & Nakamura, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-49883-7 · Cited by 38

Adipose tissue remodelling in obese subjects is a determinant of presence and severity of fatty liver disease

Cimini, F. A., Barchetta, I., Ciccarelli, G., Leonetti, F., Silecchia, G., Chiappetta, C., Cristofano, C. D., Capoccia, D., Bertoccini, L., Ceccarelli, V., et al. (2020) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3358 · Cited by 39

Activation of the adipocyte CREB/CRTC pathway in obesity

Yoon, Y., Liu, W., de Velde, S. V., Matsumura, S., Wiater, E., Huang, L., & Montminy, M. (2021) · Communications Biology · doi:10.1038/s42003-021-02735-5 · Cited by 39

Orchestration of the Adipose Tissue Immune Landscape by Adipocytes

Bradley, D. P., Deng, T., Shantaram, D., & Hsueh, W. A. (2024) · Annual Review of Physiology · doi:10.1146/annurev-physiol-042222-024353 · Cited by 44

Assessment of neuroinflammation in a mouse model of obesity and β-amyloidosis using PET

Barron, A. M., Tokunaga, M., Zhang, M., Ji, B., Suhara, T., & Higuchi, M. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0700-x · Cited by 37

Characterization of immune cells in psoriatic adipose tissue

Rose, S. M., Stansky, E., Dagur, P. K., Samsel, L., Weiner, E., Jahanshad, A., Doveikis, J., Naik, H. B., Playford, M. P., McCoy, J. P., et al. (2014) · Journal of Translational Medicine · doi:10.1186/s12967-014-0258-2 · Cited by 34

Transcriptional Regulation of Chemokine Genes: A Link to Pancreatic Islet Inflammation?

Burke, S. J., & Collier, J. J. (2015) · Biomolecules · doi:10.3390/biom5021020 · Cited by 33

Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model

Liang, J., Li, N., Zhang, Y., Hou, C., Yang, X., Shimizu, T., Wang, X., Ikenaka, K., Fan, K., & Ma, J. (2016) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2016.00152 · Cited by 34

Neutrophils as indicators of obesity‐associated inflammation: A systematic review and meta‐analysis

Gomez‐Casado, G., Jimenez‐Gonzalez, A., Rodríguez-Muñoz, A., Tinahones, F. J., González‐Mesa, E., Murri, M., & Ortega‐Gómez, A. (2024) · Obesity Reviews · doi:10.1111/obr.13868 · Cited by 31

Sodium butyrate promotes lipopolysaccharide-induced innate immune responses by enhancing mitogen-activated protein kinase activation and histone acetylation in bovine mammary epithelial cells

Dai, H., Wei, G., Wang, Y., Ma, N., Chang, G., & Shen, X. (2020) · Journal of Dairy Science · doi:10.3168/jds.2020-18198 · Cited by 32

Characterization of Dermal Stem Cells of Diabetic Patients

Ferroni, L., Gardin, C., Paola, L. D., Campo, G. C., Cimaglia, P., Bellin, G., Pinton, P., & Zavan, B. (2019) · Cells · doi:10.3390/cells8070729 · Cited by 30

Inflammatory and oxidative stress biomarkers at protein and molecular levels in workers occupationally exposed to crystalline silica

Peruzzi, C. P., Nascimento, S., Gauer, B., Nardi, J., Saüer, E., Göethel, G., Cestonaro, L. V., Fão, N., Cattani, S. A., Paim, C., et al. (2018) · Environmental Science and Pollution Research · doi:10.1007/s11356-018-3693-4 · Cited by 28

Probiotic Bifidobacterium longum subsp. longum Protects against Cigarette Smoke-Induced Inflammation in Mice

Budden, K. F., Gellatly, S. L., Vaughan, A., Amorim, N. M. L., Horvat, J. C., Hansbro, N. G., Wood, D., Hugenholtz, P., Dennis, P. G., Wark, P. A. B., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010252 · Cited by 28

Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice

Hsieh, C., Lin, C., He, J.-T., Chiang, M., Wang, Y., Tsai, Y.-C., Hung, C., & Chang, P. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-018-0915-0 · Cited by 26

17-DMAG ameliorates neuroinflammation and BBB disruption via SOX5 mediated PI3K/Akt pathway after intracerebral hemorrhage in rats

Hu, D., Mo, X., Luo, J., Wang, F., Huang, C., Xie, H., & Jin, L. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110698 · Cited by 25

Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging

Chen, J., Fan, Z., Zhu, D., Guo, Y., Ye, K., Dai, D., Guo, Z. J., Hu, Z., Miao, Y., & Qu, Q. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.728188 · Cited by 27

The Evolving Role of Neutrophils and Neutrophil Extracellular Traps (NETs) in Obesity and Related Diseases: Recent Insights and Advances

Altamura, S., Lombardi, F., Palumbo, P., Cinque, B., Ferri, C., Pinto, R. D., & Pietropaoli, D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413633 · Cited by 23

Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice

Bijnen, M., Josefs, T., Cuijpers, I., van de Gaar, J., Vroomen, M. A. M., Wijnands, E., Rensen, S. S., Greve, J. W. M., Hofker, M. H., Biessen, E. A. L., et al. (2017) · Journal of Hepatology · doi:10.1016/s0168-8278(17)31630-6 · Cited by 22

The Lyme disease bacterium, Borrelia burgdorferi, stimulates an inflammatory response in human choroid plexus epithelial cells

Thompson, D., Sorenson, J., Greenmyer, J. R., Brissette, C. A., & Watt, J. A. (2020) · PLoS ONE · doi:10.1371/journal.pone.0234993 · Cited by 24

CXCL2 combined with HVJ-E suppresses tumor growth and lung metastasis in breast cancer and enhances anti-PD-1 antibody therapy

Pan, Y. C., Nishikawa, T., Chang, C. Y., Tai, J. A., & Kaneda, Y. (2020) · Molecular Therapy — Oncolytics · doi:10.1016/j.omto.2020.12.011 · Cited by 21

Identification of key pathways and core genes involved in atherosclerotic plaque progression

Yang, R., Yao, L., Du, C., & Wu, Y. (2021) · Annals of Translational Medicine · doi:10.21037/atm-21-193 · Cited by 21

Sputnik-V reactogenicity and immunogenicity in the blood and mucosa: a prospective cohort study

Yegorov, S., Kadyrova, I., Negmetzhanov, B., Kolesnikova, Y. A., Kolesnichenko, S. I., Korshukov, I., Baiken, Y., Matkarimov, B. T., Miller, M. S., Hortelano, G., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-17514-3 · Cited by 21

Glycogen synthase kinase 3 activity enhances liver inflammation in MASH

Khoury, M., Guo, Q., Furuta, K., Correia, C., Meroueh, C., Kim Lee, H. S., Warasnhe, K., Valenzuela-Pérez, L., Mazar, A. P., Kim, I., et al. (2024) · JHEP Reports · doi:10.1016/j.jhepr.2024.101073 · Cited by 17

Host transcriptome response to Borrelia burgdorferi sensu lato

Thompson, D., Watt, J. A., & Brissette, C. A. (2020) · Ticks and Tick-borne Diseases · doi:10.1016/j.ttbdis.2020.101638 · Cited by 19

Mice with Fabp4-Cre ablation of Arid5b are resistant to diet-induced obesity and hepatic steatosis

Whitson, R. H., Li, S.-L., Zhang, G., Larson, G. P., & Itakura, K. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111246 · Cited by 16

Long Noncoding RNA U90926 Is Induced in Activated Macrophages, Is Protective in Endotoxic Shock, and Encodes a Novel Secreted Protein

Sabikunnahar, B., Caldwell, S. K., Varnum, S., Hogan, T. C., Cooper, A., Lahue, K. G., Bivona, J. J., Cousens, P. M., Symeonides, M., Ballif, B. A., et al. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2200215 · Cited by 16

Synergism between obesity and HFpEF on neutrophils phenotype and its regulation by adipose tissue‐molecules and SGLT2i dapagliflozin

Almengló, C., Fu, X., Flores-Arias, M. T., Fernández, Á. L., Viñuela, J. E., Martínez‐Cereijo, J. M., Durán, D., Rodríguez‐Mañero, M., González‐Juanatey, J. R., & Eiras-Penas, S. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17466 · Cited by 13

Elucidating the role of chemokines in inflammaging associated atherosclerotic cardiovascular diseases

Nagar, N., Naidu, G., Panda, S. K., Gulati, K., Singh, R. P., & Poluri, K. M. (2024) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2024.111944 · Cited by 11

Apolipoprotein A-IV reduced metabolic inflammation in white adipose tissue by inhibiting IKK and JNK signaling in adipocytes

Liu, X.-H., Zhang, Y., Chang, L., Wei, Y., Huang, N., Zhou, J., Cheng, C., Zhang, J., Xu, J., Li, Z., et al. (2022) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2022.111813 · Cited by 10

Whole Body Ip6k1 Deletion Protects Mice from Age-Induced Weight Gain, Insulin Resistance and Metabolic Dysfunction

Ghoshal, S., Mukherjee, S. K., Chakraborty, M., Msengi, E. N., Haubner, J., & Chakraborty, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042059 · Cited by 10

Skin as an immune organ and the site of biomimetic, non-invasive vaccination

Chopra, A., & Gupta, A. (2022) · Medicine in Novel Technology and Devices · doi:10.1016/j.medntd.2022.100196 · Cited by 10

Multi-Tissue Transcriptome Study of Innate Immune Gene Expression Profiling Reveals Negative Energy Balance Altered the Defense and Promoted System Inflammation of Dairy Cows

Dai, L., Liu, Z., Guo, L., Chai, Y., Yang, Y., Wang, Y., Ma, Y., Shi, C., & Zhang, W. (2023) · Veterinary Sciences · doi:10.3390/vetsci10020107 · Cited by 10

Sexual Dimorphism in Changes That Occur in Tissues, Organs and Plasma during the Early Stages of Obesity Development

Dhanraj, P., van Heerden, M. B., Pepper, M. S., & Ambele, M. A. (2021) · Biology · doi:10.3390/biology10080717 · Cited by 11

Implant-induced inflammatory angiogenesis is up-regulated in obese mice

Orellano, L. A. A., de Almeida, S. A., Pereira, L. X., Machado, C. T., Viana, C. T. R., Andrade, S. P., & Campos, P. P. (2020) · Microvascular Research · doi:10.1016/j.mvr.2020.104014 · Cited by 9

Anti-inflammatory effects of troxerutin are mediated through elastase inhibition

Vidhya, R., & Anuradha, C. V. (2020) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923973.2020.1806870 · Cited by 9

Long Non-Coding RNA Expression Profiling in Obesity Mice with Folic Acid Supplement

Ma, F., Li, W., Tang, R., Liu, Z., Ouyang, S., Cao, D., Li, Y., & Wu, J. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000477486 · Cited by 9

Identification and Validation of CXCL2 as a Key Gene for Childhood Obesity

He, E., Chang, K., Dong, L., Jia, M., Sun, W., & Cui, H. (2023) · Biochemical Genetics · doi:10.1007/s10528-023-10566-8 · Cited by 8

Transcriptomic profiling of long non-coding RNAs and messenger RNAs in the liver of mice during Toxoplasma gondii infection

Zou, Y., Yang, X., Chen, C., Ma, H., Cao, H., Jiang, J., Wei, X., & Zhang, X. (2024) · Parasites & Vectors · doi:10.1186/s13071-023-06053-z · Cited by 7

Molecular Mapping of Hydrogen Sulfide Targets in Normal Human Keratinocytes

Gross-Amat, O., Guillen, M., Gimeno, J., Salzet, M., Lebonvallet, N., Misery, L., Auxenfans, C., & Nataf, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21134648 · Cited by 7

Pertussis Toxin Exploits Host Cell Signaling Pathways Induced by Meningitis-Causing E. coli K1-RS218 and Enhances Adherence of Monocytic THP-1 Cells to Human Cerebral Endothelial Cells

Starost, L. J., Karassek, S., Sano, Y., Kanda, T., Kim, K., Dobrindt, U., Rüter, C., & Schmidt, M. A. (2016) · Toxins · doi:10.3390/toxins8100291 · Cited by 6

Integrative Bioinformatic Analysis of Transcriptomic Data Identifies Conserved Molecular Pathways Underlying Ionizing Radiation-Induced Bystander Effects (RIBE)

Geles, K., Vlachavas, E., Papadodima, O., Pilalis, E. D., Vorgias, C. E., Georgakilas, A. G., & Chatziioannou, A. A. (2017) · Cancers · doi:10.3390/cancers9120160 · Cited by 6

Gene-body mass index interactions are associated with methotrexate toxicity in rheumatoid arthritis

Aslibekyan, S. W., Sha, J., Redden, D. T., Moreland, L. W., O’Dell, J. R., Curtis, J. R., Mikuls, T. R., Reynolds, R. J., Danila, M. I., & Bridges, S. L. (2013) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2013-204263 · Cited by 6

A cocktail of histidine, carnosine, cysteine and serine reduces adiposity and improves metabolic health and adipose tissue immunometabolic function in ovariectomized rats

Baudin, J., Hernández-Baixauli, J., Romero‐Giménez, J., Yang, H., Mulero, F., Puiggròs, F., Mardinoğlu, A., Arola, L., & Caimari, A. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117326 · Cited by 6

Specialized Pro-Resolving Lipid Mediators Distinctly Modulate Silver Nanoparticle-Induced Pulmonary Inflammation in Healthy and Metabolic Syndrome Mouse Models

Pitchai, A., Shinde, A., Swihart, J. N., Robison‡, K. M., & Shannahan, J. H. (2024) · Nanomaterials · doi:10.3390/nano14201642 · Cited by 5

Adipose Structure (White, Brown, Beige)

Peirce, V. J., Pellegrinelli, V., & Vidal‐Puig, A. (2016) · Springer eBooks · doi:10.1007/978-3-319-11251-0_23 · Cited by 6

Effect of Fibroblast Signaling on Macrophage Polarization

LoPresti, S. T., Kulkarni, M. M., Julian, D. R., Johnson, Z. I., Lantonio, B. L., Ismail, N., Yates, C. C., & Brown, B. N. (2025) · American Journal Of Pathology · doi:10.1016/j.ajpath.2025.04.002 · Cited by 5

Cytokine mRNA Expression Profile in Target Organs of IFNAR (-/-) Mice Infected with African Horse Sickness Virus

Calvo-Pinilla, E., Jiménez-Cabello, L., Utrilla-Trigo, S., Illescas-Amo, M., & Ortego, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042065 · Cited by 4

Overfeeding induces adipose tissue release of distinct mitochondria

Goodman, J. H., Berland, C., Soni, R. K., & Ferrante, A. W. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115318 · Cited by 4

Differential gene regulation in human small airway epithelial cells grown in monoculture versus coculture with human microvascular endothelial cells following multiwalled carbon nanotube exposure

Snyder‐Talkington, B. N., Dong, C., Castranova, V., Qian, Y. R., & Guo, N. L. (2019) · Toxicology Reports · doi:10.1016/j.toxrep.2019.05.010 · Cited by 4

Bone marrow neutrophil density regulates myelopoiesis during obesity and weight loss

Waterbury, Q. T., Qian, J., Zheng, H., Dirnberger, A. S., Olson, O. C., White, R. A., Wu, F., Kobayashi, H., Malagola, E., Ochiai, Y., et al. (2025) · The Journal of Experimental Medicine · doi:10.1084/jem.20242174 · Cited by 5

Flexible adipocytes guided nano-anchoring medicine: A precision therapeutic strategy for obesity

Luo, M., Huang, J. Z., Qin, S., Peng, C., & Li, D. (2026) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2026.101666 · Cited by 3

Interleukin-10 enhances recruitment of immune cells in the neonatal mouse model of obstructive nephropathy

Wyczanska, M., Thalmeier, F., Keller, U., Klaus, R., Narasimhan, H., Ji, X., Schraml, B. U., Wackerbarth, L. M., & Lange-Sperandio, B. (2024) · Scientific Reports · doi:10.1038/s41598-024-55469-9 · Cited by 3

Bmal1 deficiency in neutrophils alleviates symptoms induced by high-fat diet

Leinweber, B., Pilorz, V., Olejniczak, I., Skrum, L., Begemann, K., Heyde, I., Stenger, S., Sadik, C. D., & Oster, H. (2025) · iScience · doi:10.1016/j.isci.2025.112038 · Cited by 3

Gene Network Analysis for Osteoporosis, Sarcopenia, Diabetes, and Obesity in Human Mesenchymal Stromal Cells

Jin, Y., Kim, D.-W., Choi, Y. J., Song, I., & Chung, Y. (2022) · Genes · doi:10.3390/genes13030459 · Cited by 3

Time-sequential changes of differentially expressed miRNAs during the process of anterior lumbar interbody fusion using equine bone protein extract, rhBMP-2 and autograft

Chen, D., Zhou, Z., Dai, X., Gao, M., Huang, B., Liang, T., Shi, R., Zou, L., Li, H., Bünger, C. E., et al. (2014) · Frontiers of Materials Science · doi:10.1007/s11706-014-0234-z · Cited by 3

Transcriptome profiling of poly(I:C)-induced RAW 264.7 mouse macrophages in response to panaxadiol

Yang, Z., Guo, D., Shen, L., Mao, G., Dai, J., Chen, S., & Yan, J. (2019) · Biologia · doi:10.2478/s11756-019-00288-x · Cited by 3

Autologous and synthetic vascular grafts trigger different host responses in the anastomotic regions and in the perivascular adipose tissue during the early healing phase

Rohringer, S., Specht, S. J., Schmitt, A.-M., Topcu, S., Schneider, K. H., Enayati, M., Grasl, C., Ehrmann, K., Baudis, S., Kiss, H., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102089 · Cited by 3

Arthritogenic Simulation of Human Synovial Fibroblasts by TWEAK

Zheng, T. S., Weng, S., Szak, S. T., & Burkly, L. C. (2007) · Clinical Immunology · doi:10.1016/j.clim.2007.03.085 · Cited by 1

Does C-C Motif Chemokine Ligand 2 (CCL2) Link Obesity to a Pro-Inflammatory State?

Dommel, S., & Blüher, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031500 · Cited by 82

CCL2 and CCL3 chemokine gene expression and their receptors in human visceral and subcutaneous adipose tissue is associated with obesity and insulin resistance

Huber, J., Kiefer, F. W., Zeyda, M., Ludvik, B. H., Silberhumer, G. R., Prager, G., & Stulnig, T. (2007) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-2007-972470 · Cited by 6

Bidirectional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation

Watanabe, Y., Nagai, Y., & Takatsu, K. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.204.supp.75.14 · Cited by 2

CC Chemokine and CC Chemokine Receptor Profiles in Visceral and Subcutaneous Adipose Tissue Are Altered in Human Obesity

Huber, J., Kiefer, F. W., Zeyda, M., Ludvik, B. H., Silberhumer, G. R., Prager, G., Zlabinger, G. J., & Stulnig, T. M. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2630 · Cited by 365