Circadian variations in plasma corticosterone permit normal termination of adrenocorticotropin responses to stress

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394

Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation

REUL, J. M. H. M., & KLOET, E. R. D. (1985) · Endocrinology · doi:10.1210/endo-117-6-2505 · Cited by 2,580

Glucocorticoid-sensitive hippocampal neurons are involved in terminating the adrenocortical stress response.

Sapolsky, R. M., Krey, L. C., & McEwen, B. S. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.19.6174 · Cited by 758

Stress Down-Regulates Corticosterone Receptors in a Site-Specific Manner in the Brain*

Sapolsky, R. M., Krey, L. C., & McEwen, B. S. (1984) · Endocrinology · doi:10.1210/endo-114-1-287 · Cited by 586

Differential Response of Type I and Type II Corticosteroid Receptors to Changes in Plasma Steroid Level and Circadian Rhythmicity

Reul, J. M. H. M., van den Bosch, F. R., & de Kloet, R. (2008) · Neuroendocrinology · doi:10.1159/000124766 · Cited by 243

Corticosterone: narrow range required for normal body and thymus weight and ACTH

Akana, S. F., Cascio, C. S., Shinsako, J., & Dallman, M. F. (1985) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1985.249.5.r527 · Cited by 199

Characterization of Rat Brain Aldosterone Receptors Reveals High Affinity for Corticosterone

Beaumont, K. C., & Fanestil, D. D. (1983) · Endocrinology · doi:10.1210/endo-113-6-2043 · Cited by 193

Effects of Destruction of the Suprachiasmatic Nuclei on the Circadian Rhythms in Plasma Corticosterone, Body Temperature, Feeding and Plasma Thyrotropin

Abe, K., Kroning, J., Greer, M. A., & CRITCHLOW, V. (2008) · Neuroendocrinology · doi:10.1159/000122913 · Cited by 189

The development of the glucocorticoid receptor system in the rat limbic brain. III. Negative-feedback regulation

Sapolsky, R. M., Meaney, M. J., & McEwen, B. S. (1985) · Developmental Brain Research · doi:10.1016/0165-3806(85)90261-5 · Cited by 158

Characterization of Corticosterone Feedback Regulation of ACTH Secretiona

Dallman, M. F., Akana, S. F., Jacobson, L., Levin, N. W., Cascio, C. S., & Shinsako, J. (1987) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1987.tb24976.x · Cited by 129

Neuroendocrinology of Stress

McEwen, B. S., & Chattarji, S. (2006) · Springer eBooks · doi:10.1007/978-0-387-30405-2_14 · Cited by 30

Chronic Exposure to Morphine Decreases Physiologically Active Corticosterone in Both Male and Female Rats but by Different Mechanisms

Nock, B. L., Cicero, T. J., & Wich, M. (1998) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37664-5 · Cited by 30

Chronic Stress, Physiological Adaptation and Developmental Programming of the Neuroendocrine Stress System

Coffman, J. A. (2020) · Future Neurology · doi:10.2217/fnl-2019-0014 · Cited by 33

Ontogeny of the HPA axis of the CD1 mouse following 24 h maternal deprivation at pnd 3

Enthoven, L., Schmidt, M. V., Cheung, Y. H., van der Mark, M. H., de Kloet, E. R., & Oitzl, M. S. (2009) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2009.10.006 · Cited by 27

Blockade of the hypothalamic-pituitary-adrenal response to stress by intraventricular injection of dexamethasone: A method for studying the stress-induced peripheral effects of glucocorticoids

Fleshner, M., Watkins, L. R., Lockwood, L. L., Grahn, R. E., Gerhardt, G. A., Meaney, M. J., Laudenslager, M. L., & Maier, S. F. (1993) · Psychoneuroendocrinology · doi:10.1016/0306-4530(93)90022-d · Cited by 28

Effects of Prenatal Ethanol Exposure on Hypothalamic-Pituitary-Adrenal Regulation After Adrenalectomy and Corticosterone Replacement

Glavas, M. M., Hofmann, C. E., Yu, W. K., & Weinberg, J. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-200106000-00015 · Cited by 28

Glucocorticoids mediate stress induction of the alarmin HMGB1 and reduction of the microglia checkpoint receptor CD200R1 in limbic brain structures

Frank, M. G., Annis, J. L., Watkins, L. R., & Maier, S. F. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.05.014 · Cited by 28

The importance of corticosterone in mediating restraint-induced weight loss in rats

Scherer, I. J., Holmes, P. V., & Harris, R. B. S. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.11.014 · Cited by 27

Chronic Exposure to Morphine Increases Corticosteroid-Binding Globulin

Nock, B. L., Wich, M., & Cicero, T. J. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36910-1 · Cited by 27

Late glucocorticoid receptor antagonism changes the outcome of adult life stress

Ding, J., da Silva, M. S., Lingeman, J., Chen, X., Shi, Y., Han, F., & Meijer, O. C. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.05.014 · Cited by 26

Gender-Dependent Effects of Early Maternal Separation and Variable Chronic Stress on Vasopressinergic Activity and Glucocorticoid Receptor Expression in Adult Rats

Renard, G. M., Rivarola, M. A., & Suárez, M. M. (2010) · Developmental Neuroscience · doi:10.1159/000280102 · Cited by 26

Chronic corticotropin-releasing hormone and vasopressin regulate corticosteroid receptors in rat hippocampus and anterior pituitary

Hügin-Flores, M. E., Steimer, T. J., Schulz, P., Vallotton, M. B., & Aubert, M. L. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02585-x · Cited by 23

Connecting dots of long COVID-19 pathogenesis: a vagus nerve- hypothalamic-pituitary- adrenal-mitochondrial axis dysfunction

Camici, M., Duca, G. D., Brita, A. C., & Antinori, A. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1501949 · Cited by 25

Stressed Microglia: Neuroendocrine–Neuroimmune Interactions in the Stress Response

Sequeira, M. K., & Bolton, J. L. (2023) · Endocrinology · doi:10.1210/endocr/bqad088 · Cited by 26

Glucocorticoid-dependent stimulation of adiposity and appetite by a ghrelin mimetic in the rat

Tung, Y. C. L., Hewson, A. K., & Dickson, S. L. (2004) · European Journal of Endocrinology · doi:10.1530/eje.0.1500905 · Cited by 22

Preserving neuroplasticity: Role of glucocorticoids and neurotrophins via phosphorylation

McEwen, B. S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1521416112 · Cited by 21

Acute-Stress-Induced Facilitation of the Hypothalamic-Pituitary-Adrenal Axis

Wong, Y. N., Cassano, W. J., & D’mello, A. P. (2000) · Neuroendocrinology · doi:10.1159/000054556 · Cited by 19

Plasma ACTH, beta-endorphin, prolactin, growth hormone and luteinizing hormone levels after thermal stress, heat and cold

Vescovi, P., Casti, A., Michelini, M., Maninetti, L., Pedrazzoni, M., & Passeri, M. (1992) · Stress Medicine · doi:10.1002/smi.2460080310 · Cited by 17

Corticosterone and progesterone differentially regulate HPA axis and neuroimmune responses to stress in male rats

Hueston, C. M., & Terrence Deak, B. (2019) · Stress · doi:10.1080/10253890.2019.1678025 · Cited by 18

Tonic, But Not Phasic Corticosterone, Constrains Stress ActivatedExtracellular-Regulated-Kinase 1/ 2 Immunoreactivity Within the Hypothalamic Paraventricular Nucleus

Osterlund, C., Jarvis, E., Chadayammuri, A. P., Unnithan, R., Weiser, M. J., & Spencer, R. L. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02220.x · Cited by 18

Intracerebral interleukin-1β impairs response to tumor invasion: involvement of adrenal catecholamines

Hodgson, D. M., Yirmiya, R., Chiappelli, F., & Taylor, A. N. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01185-8 · Cited by 17

Cortisol Awakening Response: An Ancient Adaptive Feature

Contreras, C. M., & Gutiérrez‐García, A. G. (2018) · Journal of Psychiatry and Psychiatric Disorders · doi:10.26502/jppd.2572-519x0038 · Cited by 15

From serendipity to clinical relevance: How clinical psychology and neuroscience converged to illuminate psychoneuroendocrinology

McEwen, B. S. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.09.011 · Cited by 10

Sex Differences in Ethanol‐Induced Hypothermia in Ethanol‐Naïve and Ethanol‐Dependent/Withdrawn Rats

Taylor, A. N., Tio, D. L., Bando, J. K., Truong, A. H., & Prolo, P. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00811.x · Cited by 9

Variations in Corticosterone Feedback Do Not Reveal Differences in HPA Activity After Prenatal Ethanol Exposure

Gabriel, K. I., Ellis, L. A., Yu, W. K., & Weinberg, J. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-200106000-00017 · Cited by 9

Food Intake After an Overnight Fast is not Affected by Acute Alterations in Corticosterone but is Decreased by Chronic Adrenalectomy

Hanson, E. S., Akana, S. F., Strack, A. M., Horsley, C. J., de Santana, P. T., & Dallman, M. F. (1996) · Stress · doi:10.3109/10253899609001098 · Cited by 5

Stress Responsiveness of BDNF/TrkB Signaling in the Neuroendocrine System and Future Implications

Azogu‐Sepe, I., & Plamondon, H. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-813156-5.00013-3 · Cited by 3

What Is the Role of Glucocorticoids in the Effects of Stress on the Brain?

Benarroch, E. E. (2025) · Neurology · doi:10.1212/wnl.0000000000213874 · Cited by 4

Role of Endogenous Glucocorticoids in Immune System Function: Regulation and Counterregulation

Spencer, R. L., Kalman, B. A., & Dhabhar, F. S. (2000) · Comprehensive physiology · doi:10.1002/j.2040-4603.2000.tb01523.x · Cited by 2

Chronic stress parameters in pigs

de Jong, I. C. (2000) · Cited by 1

Neuroendocrinology and Neurotransmitters

Gray, J. D., & McEwen, B. S. (2014) · Wiley eBooks · doi:10.1002/9781118775349.ch16 · Cited by 1

Abundance of Degrees of Freedom

(2008) · Springer eBooks · doi:10.1007/978-3-540-29678-2_19 · Cited by 1

Adrenal cortex: scalpels, syringes, and separatory funnels

Akana, S. F. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/classicessays.00002.2004

satiety-related responses associated with an increased activation of Hypophagia induced by glucocorticoid deficiency is

Uchôa, E. T., Augusto, H., Sabino, C., Ruginsk, S. G., Rinaman, L., la Fleur, E., Serlie, M. J. M., Fliers, E., Buijs, R. M., Tschöp, M. H., et al. (2015)

3D reconstruction of synaptic and nuclear corticosteroid receptors distribution density in the amygdala: a feasibility study

Koo, S. (2017) · Queensland University of Technology · doi:10.5204/thesis.eprints.103629

Hypothalamic pituitary adrenal axis dysregulation in obese pregnancy

Stirrat, L. (2018) · ERA

Stress Response

Cullinan, W. E. (2008) · Springer eBooks · doi:10.1007/978-3-540-29678-2_5686

Mary F. Dallman

Bhatnagar, S., & Walker, C. (2022) · Springer eBooks · doi:10.1007/978-3-031-12970-4_17

An Emerging Role for Gut-Brain Signaling Involving Ghrelin in Chronic Stress

Salcido, A. A., Reyes, N. F., Macias, A. Y., Batson, S. A., Beck, D. W., Friedman, A., & Goosens, K. A. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-89525-8_7

Corticosterone-Induced Potentiation of Cocaine Seeking: A Potential Role for Organic Cation Transporter 3

Graf, E. N. (2012) · e-Publications@Marquette (Marquette University)

Development of Individual Differences in Behavioral and Endocrine Responses to Stress: Role of the Postnatal Environment

Caldji, C., Liu, D., Sharma, S., Diorio, J. C., Francis, D., Meaney, M. J., & Plotsky, P. M. (2000) · Comprehensive physiology · doi:10.1002/j.2040-4603.2000.tb01518.x

Factors determining the time-course of the response of the hypothalamus-pituitary-adrenal axis to stress: Much more than negative glucocorticoid feedback

Armario, A. (2026) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2026.101287

Augmented ACTH Responses to Stress in Adrenalectomized Rats Replaced with Constant, Physiological Levels of Corticosterone Are Partially Normalized by Acute Increases in Corticosterone

Jacobson, L., & Sapolsky, R. M. (2008) · Neuroendocrinology · doi:10.1159/000126571 · Cited by 28

Circadian Patterns of Stress-Induced ACTH Secretion Are Modified by Corticosterone Responses

Engeland, W. C., Shinsako, J., Winget, C. M., Vernikos, J., & Dallman, M. F. (1977) · Endocrinology · doi:10.1210/endo-100-1-138 · Cited by 96

Stress-Induced Adrenocorticotropin Secretion: Diurnal Responses and Decreases During Stress in the Evening Are Not Dependent on Corticosterone*

BRADBURY, M. J., Cascio, C. S., Scribner, K. A., & Dallman, M. F. (1991) · Endocrinology · doi:10.1210/endo-128-2-680 · Cited by 139

[Evaluation of the inhibitory effect of circulating corticosteroids on circadian stimulated and stress induced secretion of ACTH in rats].

IXART, G., SZAFARCZYK, A., Malaval, F., Nouguier-Soulé, J., & ASSENMACHER, I. (1985) · PubMed

Circadian corticosterone rhythm and stress response in rats with adrenal autotransplants

Gibson, M. J., & Krieger, D. T. (1981) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1981.240.4.e363 · Cited by 21