The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Growth Enhancement of Transgenic Mice Expressing Human Insulin-Like Growth Factor I*
Abstract
A line of transgenic mice carrying a chimeric gene composed of human insulin-like growth factor I (IGF-I) coding sequences fused to the mouse metallothionein I promoter was generated to study the effects of chronically elevated exposure to IGF-I. Mice in this line overexpress IGF-I in most tissues studied and have circulating IGF-I levels 1.5 times the normal value. This results in a growth response manifested by a 1.3-fold increase in weight as a result of selective organomegaly without an apparent increase in skeletal growth. In addition, expression of the endogenous GH and IGF-I genes is inhibited. These results are consistent with IGF-I playing an important role in the control of somatic growth.
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Cites
Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth Hormone
Brazeau, P., Vale, W., Burgus, R., Ling, N., Butcher, M., Rivier, J., & Guillemin, R. (1973) · Science · doi:10.1126/science.179.4068.77 · Cited by 3,532
Palmiter, R. D., Brinster, R. L., Hammer, R. E., Trumbauer, M. E., Rosenfeld, M. G., Birnberg, N. C., & Evans, R. M. (1982) · Nature · doi:10.1038/300611a0 · Cited by 1,340
Self-citationD'Ercole, A. J., Stiles, A. D., & Underwood, L. E. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.3.935 · Cited by 1,186
Self-citationCharacterization of a growth hormone-releasing factor from a human pancreatic islet tumour
Rivier, J., Spiess, J., Thorner, M., & Vale, W. (1982) · Nature · doi:10.1038/300276a0 · Cited by 1,104
Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.
Brinster, R. L., Chen, H. Y., Trumbauer, M. E., Yagle, M. K., & Palmiter, R. D. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.13.4438 · Cited by 1,027
Self-citationSomatomedin: Proposed Designation for Sulphation Factor
DAUGHADAY, W. H., HALL, K., RABEN, M. S., SALMON, W. D., LEO VAN DEN BRANDE, J., & VAN WYK, J. J. (1972) · Nature · doi:10.1038/235107a0 · Cited by 842
Berelowitz, M., Szabo, M., Frohman, L. A., Firestone, S., Chu, L., & Hintz, R. L. (1981) · Science · doi:10.1126/science.6262917 · Cited by 829
Introns increase transcriptional efficiency in transgenic mice.
Brinster, R. L., Allen, J. M., Behringer, R. R., Gelinas, R. E., & Palmiter, R. D. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.3.836 · Cited by 722
Self-citationMetallothionein-Human GH Fusion Genes Stimulate Growth of Mice
Palmiter, R. D., Norstedt, G., Gelinas, R. E., Hammer, R. E., & Brinster, R. L. (1983) · Science · doi:10.1126/science.6356363 · Cited by 676
Self-citationInsulin-like growth factor I stimulates growth in hypophysectomized rats
Schoenle, E., Zapf, J., Humbel, R. E., & Froesch, E. R. (1982) · Nature · doi:10.1038/296252a0 · Cited by 596
Cited by
Fero, M. L., Rivkin, M., Tasch, M., Porter, P., Carow, C. E., Firpo, E., Polyak, K., Tsai, L.-H., Broudy, V., Perlmutter, R. M., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81239-8 · Cited by 1,457
Cell death and control of cell survival in the oligodendrocyte lineage
Barres, B. A., Hart, I. K., Coles, H. S. R., Burne, J. F., Voyvodic, J. T., Richardson, W. D., & Raff, M. C. (1992) · Cell · doi:10.1016/0092-8674(92)90531-g · Cited by 1,345
The Somatomedin Hypothesis: 2001
Le Roith, D., Bondy, C., Yakar, S., Liu, J.-L., & Butler, A. (2001) · Endocrine Reviews · doi:10.1210/edrv.22.1.0419 · Cited by 1,257
Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27
Kiyokawa, H., Kineman, R. D., Manova-Todorova, K. O., Soares, V. C., Hoffman, E. S., Ono, M., Khanam, D., Hayday, A. C., Frohman, L. A., & Koff, A. (1996) · Cell · doi:10.1016/s0092-8674(00)81238-6 · Cited by 1,251
Musarò, A., McCullagh, K., Paul, A., Houghton, L., Dobrowolny, G., Molinaro, M., Barton, E. R., L Sweeney, H., & Rosenthal, N. (2001) · Nature Genetics · doi:10.1038/84839 · Cited by 1,137
Metadata
- Authors
- MATHEWS, L. S., HAMMER, R. E., BEHRINGER, R. R., D'ERCOLE, A. J., BELL, G. I., BRINSTER, R. L., & PALMITER, R. D.
- Venue
- Endocrinology
- Publisher
- The Endocrine Society
- Published
- 1988-12
- Volume
- 123
- Issue
- 6
- Pages
- 2827-2833
- ISSN
- 0013-7227 (ISSN-L)
- 1945-7170
- OpenAlex
- W2115073960
- Cited by
- 477
- References
- 41
- FWCI
- 10.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Growth Enhancement of Transgenic Mice Expressing Human Insulin-Like Growth Factor I*. https://app.cochat.ai/papers/10.1210/endo-123-6-2827
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- MATHEWS, L. S., HAMMER, R. E., BEHRINGER, R. R., D'ERCOLE, A. J., BELL, G. I., BRINSTER, R. L., & PALMITER, R. D. (1988). Growth Enhancement of Transgenic Mice Expressing Human Insulin-Like Growth Factor I*. Endocrinology. https://doi.org/10.1210/endo-123-6-2827
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
