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ASSAY OF THE FOLLICLE STIMULATING HORMONE BASED ON THE AUGMENTATION WITH HUMAN CHORIONIC GONADOTROPIN
Abstract
INTRODUCTION There have been in the past numerous attempts to quantitatively assay the follicle stimulating hormone (FSH) of the anterior pituitary. Fevold et al. (1937, 1940) and many others have used the increase in ovarian weight in immature female rats. Evans et al. (1939) have employed an histological assay based upon the production of healthy (nonatretic) follicles with small antra in the ovaries of hypophysectomized female rats. Many other workers use uterine weight as a criterion for the estimation of FSH activity. In hypophysectomized male rats Greep et al. (1940, 1942) have employed the increase in testicular weight, in the absence of hypertrophy of the prostate and seminal vesicles, as a means of determination of FSH. It has been known for some time that human chorionic gonadotropin (HCG) will augment the action of FSH in the ovary. Bates and Schooley (1942) in their excellent article on this subject indicated that it might be possible to use it as an assay method.
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Citations
Cited by
Schally, A. V., Arimura, A., Kastin, A. J., Matsuo, H., Baba, Y., Redding, T. W., Nair, R. M. G., Debeljuk, L., & White, W. F. (1971) · Science · doi:10.1126/science.173.4001.1036 · Cited by 770
Isolation and properties of the FSH and LH-releasing hormone
Schally, A. V., Arimura, A., Baba, Y., Nair, R. M. G., Matsuo, H., Redding, T. W., Debeljuk, L., & White, W. F. (1971) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(71)90766-2 · Cited by 665
Purification of a fibroblast growth factor from bovine pituitary.
Gospodarowicz, D. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)41631-1 · Cited by 591
17-Hydroxylation deficiency in man
Biglieri, E. G., Herron, M. A., & Brust, N. (1966) · Journal of Clinical Investigation · doi:10.1172/jci105499 · Cited by 561
CLINICAL EFFECT OF HUMAN PITUITARY FOLLICLE-STIMULATING HORMONE (FSH)*
GEMZELL, C. A., DICZFALUSY, E., & TILLINGER, G. (1958) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-18-12-1333 · Cited by 332
Metadata
- Authors
- STEELMAN, S. L., & POHLEY, F. M.
- Venue
- Endocrinology
- Publisher
- The Endocrine Society
- Published
- 1953-12
- Volume
- 53
- Issue
- 6
- Pages
- 604-616
- ISSN
- 0013-7227 (ISSN-L)
- 1945-7170
- OpenAlex
- W1990477940
- Cited by
- 696
- References
- 0
- FWCI
- 13.77
- Type
- journal article
- Language
- en
- Open access
- closed
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- STEELMAN, S. L., & POHLEY, F. M. (1953). ASSAY OF THE FOLLICLE STIMULATING HORMONE BASED ON THE AUGMENTATION WITH HUMAN CHORIONIC GONADOTROPIN. Endocrinology. https://doi.org/10.1210/endo-53-6-604
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
