Cited by 101Adipose Tissue and MetabolismHormonal Regulation and HypertensionEstrogen and related hormone effects

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Aldosterone stimulated differentiation of mouse 3T3-L1 cells into adipocytes

Rondinone, C M, Rodbard, D, Baker, M E·1993·Endocrinology

Open this paper in CoChat — free account

Abstract

We find that 1-10 nM aldosterone can induce differentiation of 3T3-L1 cells into adipose cells as evaluated by microscopic accumulation of fat droplets and quantitative measurement of triglycerides and of glycerol-3-phosphate dehydrogenase, an enzyme specific for adipocyte differentiation. Moreover, the aldosterone antagonist ZK91587 inhibits aldosterone-but not glucocorticoid-mediated differentiation of 3T3-L1 cells. Steroid binding assays with 3T3-L1 cells indicate the presence of specific binding sites for aldosterone. We conclude that there is an aldosterone receptor-mediated pathway for terminal differentiation of 3T3-L1 cells into adipose cells. Receptors for aldosterone have also been found in a variety of cells that do not function to regulate sodium and potassium transport. The aldosterone receptor may have a role in regulation expression of genes involved in differentiation of these cells.

Integrity signals

Registry

Crossref · 10.1210/endo.132.6.8504747

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The cellular action of aldosterone in target epithelia
Bastl, C. P., & Hayslett, J. P. (1992) · Kidney International · doi:10.1038/ki.1992.284 · Cited by 74
[Micropuncture research on the effect of aldosterone, cortisone and dexamethasone on renal sodium resorption in adrenalectomized rats].
Wiederholt, M., Stolte, H., Jp, B., & Hierholzer, K. (1966) · PubMed · Cited by 38
Paradoxical differences in the receptor binding of two new antimineralocorticoids
Agarwal, M. K. (1988) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(88)90073-6 · Cited by 16

Show all 3 references

Sorted by citations

The adipose-tissue renin–angiotensin–aldosterone system: role in the metabolic syndrome?
Engeli, S., Schling, P., Gorzelniak, K., Boschmann, M., Janke, J., Ailhaud, G. P., Teboul, M., Massiéra, F., & Sharma, A. M. (2003) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(02)00311-4 · Cited by 416
Narrative Review: The Emerging Clinical Implications of the Role of Aldosterone in the Metabolic Syndrome and Resistant Hypertension
Sowers, J. R., Whaley-Connell, A., & Epstein, M. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-150-11-200906020-00005 · Cited by 351
Mineralocorticoid Receptor Blockade Reverses Obesity-Related Changes in Expression of Adiponectin, Peroxisome Proliferator-Activated Receptor-γ, and Proinflammatory Adipokines
Guo, C., Ricchiuti, V., Lian, B. Q., Yao, T. M., Coutinho, P., Romero, J. R., Li, J., Williams, G. H., & Adler, G. K. (2008) · Circulation · doi:10.1161/circulationaha.107.748640 · Cited by 342
Pivotal role of the mineralocorticoid receptor in corticosteroid‐induced adipogenesis
Caprio, M., Fève, B., Claës, A., Viengchareun, S., Lombès, M., & Zennaro, M.-C. (2007) · The FASEB Journal · doi:10.1096/fj.06-7970com · Cited by 337
The Mineralocorticoid Receptor: Insights into its Molecular and (Patho)Physiological Biology
Viengchareun, S., Menuet, D. L., Martinerie, L., Munier, M., Tallec, L. P.-L., & Lombès, M. (2007) · Nuclear Receptor Signaling · doi:10.1621/nrs.05012 · Cited by 342
Differentiation of Adipose Stromal Cells: The Roles of Glucocorticoids and 11 -Hydroxysteroid Dehydrogenase
Bujalska, I. J., Kumar, S., Hewison, M., & Stewart, P. M. (1999) · Endocrinology · doi:10.1210/endo.140.7.6868 · Cited by 258
Visceral Obesity and Insulin Resistance Are Associated with Plasma Aldosterone Levels in Women
Goodfriend, T. L., Kelley, D. E., Goodpaster, B. H., & Winters, S. J. (1999) · Obesity Research · doi:10.1002/j.1550-8528.1999.tb00418.x · Cited by 234
Multimarker Approach to Evaluate the Incidence of the Metabolic Syndrome and Longitudinal Changes in Metabolic Risk Factors
Ingelsson, E., Pencina, M. J., Tofler, G. H., Benjamin, E. J., Lanier, K. J., Jacques, P. F., Fox, C. S., Meigs, J. B., Levy, D. A., Larson, M. G., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.708537 · Cited by 195
Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high‐fat‐diet‐fed mice
Armani, A., Cinti, F., Marzolla, V., Morgan, J., Cranston, G. A., Antelmi, A., Carpinelli, G., Canese, R., Pagotto, U., Quarta, C., et al. (2014) · The FASEB Journal · doi:10.1096/fj.13-245415 · Cited by 176
Protein Tyrosine Phosphatase 1B Reduction Regulates Adiposity and Expression of Genes Involved in Lipogenesis
Rondinone, C. M., Trevillyan, J. M., Clampit, J. E., Gum, R. J., Berg, C., Kroeger, P., Frost, L., Zinker, B. A., Reilly, R., Ulrich, R. G., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.8.2405 · Cited by 159
Self-citation
Aldosterone: Role in the Cardiometabolic Syndrome and Resistant Hypertension
Whaley‐Connell, A. T., Johnson, M. S., & Sowers, J. R. (2010) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2009.12.004 · Cited by 155
Antiadipogenic effects of the mineralocorticoid receptor antagonist drospirenone: potential implications for the treatment of metabolic syndrome.
Caprio, M., Antelmi, A., Chetrite, G., Muscat, A., Mammi, C., Marzolla, V., Fabbri, A., Zennaro, M., & Fève, B. (2010) · Endocrinology · doi:10.1210/en.2010-0674 · Cited by 139
Glucose Metabolism Abnormalities in Cushing Syndrome: From Molecular Basis to Clinical Management
Scaroni, C., Zilio, M., Foti, M., & Boscaro, M. (2017) · Endocrine Reviews · doi:10.1210/er.2016-1105 · Cited by 140
Hibernoma development in transgenic mice identifies brown adipose tissue as a novel target of aldosterone action.
Zennaro, M., Menuet, D. L., Viengchareun, S., Walker, F., Ricquier, D., & Lombès, M. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1915 · Cited by 132
The role of the mineralocorticoid receptor in adipocyte biology and fat metabolism
Marzolla, V., Armani, A., Zennaro, M., Cinti, F., Mammi, C., Fabbri, A., Rosano, G. M. C., & Caprio, M. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.011 · Cited by 131
Exercise in the Metabolic Syndrome
Golbidi, S., Mesdaghinia, A., & Laher, I. (2012) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2012/349710 · Cited by 127
The balance between gluco- and mineralo-corticoid action critically determines inflammatory adipocyte responses
Hoppmann, J., Perwitz, N., Meier, B., Faßhauer, M., Hadaschik, D., Lehnert, H., & Klein, J. C. (2009) · Journal of Endocrinology · doi:10.1677/joe-09-0292 · Cited by 124
11β-hydroxysteroid dehydrogenase 1 in adipocytes: Expression is differentiation-dependent and hormonally regulated
Napolitano, A., Voice, M. W., Edwards, C. R. W., Seckl, J. R., & Chapman, K. E. (1998) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(97)00200-8 · Cited by 118
Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase
Urbanet, R., Nguyen Dinh Cat, A., Feraco, A., Venteclef, N., El Mogrhabi, S., Sierra-Ramos, C., Alvarez de la Rosa, D., Adler, G. K., Quilliot, D., Rossignol, P., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.114.04981 · Cited by 114
RAAS Activation Is Associated With Visceral Adiposity and Insulin Resistance Among HIV-infected Patients
Srinivasa, S., Fitch, K. V., Wong, K., Torriani, M., Mayhew, C., Stanley, T. L., Lo, J., Adler, G. K., & Grinspoon, S. K. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-1461 · Cited by 93
Adipose tissue renin–angiotensin–aldosterone system (RAAS) and progression of insulin resistance
Marcus, Y., Shefer, G., & Stern, N. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.06.021 · Cited by 92
Adiponectin Deficiency, Diastolic Dysfunction, and Diastolic Heart Failure
Sam, F., Duhaney, T.-A. S., Sato, K., Wilson, R. M., Ohashi, K., Sono-Romanelli, S., Higuchi, A., Silva, D. S. D., Qin, F., Walsh, K., et al. (2009) · Endocrinology · doi:10.1210/en.2009-0806 · Cited by 90
Different inactivating mutations of the mineralocorticoid receptor in fourteen families affected by type I pseudohypoaldosteronism
Sartorato, P., Lapeyraque, A.-L., Armanini, D., Kuhnle, U., Khaldi, Y., Salomon, R., Abadie, V., Di Battista, E., Naselli, A., Racine, A., et al. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021932 · Cited by 85
General overview of mineralocorticoid hormone action
Agarwal, M. K., & Mirshahi, M. (1999) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(99)00038-8 · Cited by 87
Mineralocorticoid Receptors in Metabolic Syndrome: From Physiology to Disease
Feraco, A., Marzolla, V., Scuteri, A., Armani, A., & Caprio, M. (2019) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2019.11.006 · Cited by 83
The mineralocorticoid receptor mediates aldosterone-induced differentiation of T37i cells into brown adipocytes
Penfornis, P., Viengchareun, S., Menuet, D. L., Cluzeaud, F., Zennaro, M., & Lombès, M. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.2.e386 · Cited by 83
Mineralocorticoid receptors in the metabolic syndrome
Zennaro, M., Caprio, M., & Fève, B. (2009) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2009.05.006 · Cited by 84
Mitochondrial oxidative stress in obesity: role of the mineralocorticoid receptor
Lefranc, C., Friederich‐Persson, M., Palacios, R., & Cat, A. N. D. (2018) · Journal of Endocrinology · doi:10.1530/joe-18-0163 · Cited by 80
Updated survey of the steroid-converting enzymes in human adipose tissues
Tchernof, A., Mansour, M. F., Pelletier, M., Boulet, M.-M., Nadeau, M., & Luu-The, V. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.11.011 · Cited by 73
Mineralocorticoid receptor in adipocytes and macrophages: A promising target to fight metabolic syndrome
Marzolla, V., Armani, A., Feraco, A., Martino, M. U. D., Fabbri, A., Rosano, G. M. C., & Caprio, M. (2014) · Steroids · doi:10.1016/j.steroids.2014.05.001 · Cited by 75
The mineralocorticoid signaling pathway throughout development: Expression, regulation and pathophysiological implications
Martinerie, L., Munier, M., Menuet, D. L., Méduri, G., Viengchareun, S., & Lombès, M. (2012) · Biochimie · doi:10.1016/j.biochi.2012.09.030 · Cited by 75
Mineralocorticoid receptor activation in obesity hypertension
Nagase, M., & Fujita, T. (2009) · Hypertension Research · doi:10.1038/hr.2009.86 · Cited by 64
Obesity and CKD progression: hard facts on fat CKD patients
Mallamaci, F., & Tripepi, G. L. (2013) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gft391 · Cited by 61
Role of mineralocorticoid receptor and renin–angiotensin–aldosterone system in adipocyte dysfunction and obesity
Feraco, A., Armani, A., Mammi, C., Fabbri, A., Rosano, G. M. C., & Caprio, M. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.02.012 · Cited by 58
Lipocalin‐2—The myth of its expression and function
Li, D., Sun, W. Y., Fu, B., Xu, A., & Wang, Y. (2019) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13332 · Cited by 54
Inflammation and Fibrosis in Perirenal Adipose Tissue of Patients With Aldosterone-Producing Adenoma
Wu, C., Zhang, H., Zhang, J., Xie, C., Fan, C., Zhang, H., Wu, P., Wei, Q., Tan, W., Xu, L., et al. (2017) · Endocrinology · doi:10.1210/en.2017-00651 · Cited by 51
Visceral adipose tissue: emerging role of gluco‐ and mineralocorticoid hormones in the setting of cardiometabolic alterations
Boscaro, M., Giacchetti, G., & Ronconi, V. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06597.x · Cited by 51
Cerebro-Cardiovascular Risk, Target Organ Damage, and Treatment Outcomes in Primary Aldosteronism
Lin, X., Ullah, M. H. E., Xiong, W., Xu, F., Shan, S., Lei, L.-M., Yuan, L., & Liu, J. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.798364 · Cited by 45
Obesity, sleep apnea, aldosterone, and hypertension
Goodfriend, T. L. (2008) · Current Hypertension Reports · doi:10.1007/s11906-008-0042-x · Cited by 44
Aldosterone, From (Patho)Physiology to Treatment in Cardiovascular and Renal Damage
Waanders, F., de Vries, L. V., van Goor, H., Hillebrands, J., Laverman, G. D., Bakker, S. J. L., & Navis, G. J. (2011) · Current Vascular Pharmacology · doi:10.2174/157016111796642689 · Cited by 41
Lipocalin-2 derived from adipose tissue mediates aldosterone-induced renal injury
Sun, W. Y., Bai, B., Luo, C., Yang, K., Li, D., Wu, D., Félétou, M., Villeneuve, N., Zhou, Y., Yang, J., et al. (2018) · JCI Insight · doi:10.1172/jci.insight.120196 · Cited by 39
Role of the Renin–Angiotensin– Aldosterone System in the Metabolic Syndrome
Engeli, S. (2006) · KARGER eBooks · doi:10.1159/000095324 · Cited by 40
The mineralocorticoid receptor—an emerging player in metabolic syndrome?
Thuzar, M., & Stowasser, M. (2021) · Journal of Human Hypertension · doi:10.1038/s41371-020-00467-3 · Cited by 38
Interleukin-33/ST2 system attenuates aldosterone-induced adipogenesis and inflammation
Martínez‐Martínez, E., Cachofeiro, V., Rousseau, E., Álvarez, V., Calvier, L., Fernández‐Celis, A., Leroy, C., Miana, M., Jurado-López, R., Briones, A. M., et al. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.04.007 · Cited by 36
Mineralocorticoid receptors in the pathophysiology of chronic kidney diseases and the metabolic syndrome
Shibata, S., & Fujita, T. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.07.018 · Cited by 34
Cellular mechanisms of MR regulation of adipose tissue physiology and pathophysiology
Armani, A., Marzolla, V., Fabbri, A., & Caprio, M. (2015) · Journal of Molecular Endocrinology · doi:10.1530/jme-15-0122 · Cited by 35
Mineralocorticoid Receptor and Aldosterone-Related Biomarkers of End-Organ Damage in Cardiometabolic Disease
Gorini, S., Marzolla, V., Mammi, C., Armani, A., & Caprio, M. (2018) · Biomolecules · doi:10.3390/biom8030096 · Cited by 36
A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet
Mammi, C., Marzolla, V., Armani, A., Feraco, A., Antelmi, A., Maślak, E., Chłopicki, S., Cinti, F., Hunt, H., Fabbri, A., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.13 · Cited by 33
The renin–angiotensin–aldosterone system in adolescent offspring born prematurely to mothers with preeclampsia
Washburn, L. K., Brosnihan, K. B., Chappell, M. C., Diz, D. I., Gwathmey, T. M., Nixon, P. A., Russell, G. B., Snively, B. M., & O’Shea, T. M. (2014) · Journal of the Renin-Angiotensin-Aldosterone System · doi:10.1177/1470320314526940 · Cited by 29
Dietary fructose-related adiposity and glucocorticoid receptor function in visceral adipose tissue of female rats
Kovačević, S., Brkljačić, J. M., Matić, G. M., & Elaković, I. (2014) · European Journal of Nutrition · doi:10.1007/s00394-013-0644-1 · Cited by 30
Inhibition by aldosterone of insulin receptor mRNA levels and insulin binding in U-937 human promonocytic cells.
Campión, J., Maestro, B., Mata, F., Dȧvila, N., Carranza, M., & Calle, C. (1999) · Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(99)00117-x · Cited by 30
Resistant Hypertension in the High-Risk Metabolic Patient
Chaudhary, K. R., Buddineni, J. P., Nistala, R., & Whaley‐Connell, A. T. (2010) · Current Diabetes Reports · doi:10.1007/s11892-010-0155-x · Cited by 26
The metabolic syndrome in primary aldosteronism
Fallo, F., Federspil, G., Veglio, F., & Mulatero, P. (2008) · Current Diabetes Reports · doi:10.1007/s11892-008-0009-y · Cited by 28
Relationship between the Balance of Hypertrophic/Hyperplastic Adipose Tissue Expansion and the Metabolic Profile in a High Glucocorticoids Model
Zubiría, M. G., Alzamendi, A., Moreno, G., Portales, A. E., Castrogiovanni, D. C., Spinedi, E., & Giovambattista, A. (2016) · Nutrients · doi:10.3390/nu8070410 · Cited by 24
Eplerenone Implantation Improved Adipose Dysfunction Averting RAAS Activation and Cell Division
Vecchiola, A., Fuentes, C., Solar, I., Lagos, C. F., Opazo, M. C., Muñoz‐Durango, N., Riedel, C. A., Owen, G. I., Kalergis, A. M., & Fardella, C. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00223 · Cited by 23
Randomized, Placebo-Controlled Trial to Evaluate Effects of Eplerenone on Metabolic and Inflammatory Indices in HIV
Srinivasa, S., Fitch, K. V., Wong, K., O’Malley, T. K., Maehler, P., Branch, K. L., Looby, S. E. D., Burdo, T. H., Martínez-Salazar, E. L., Torriani, M., et al. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-00330 · Cited by 23
The metabolic syndrome in primary aldosteronism
Fallo, F., Federspil, G., Veglio, F., & Mulatero, P. (2007) · Current Hypertension Reports · doi:10.1007/s11906-007-0019-1 · Cited by 23
Adipose cell–adrenal interactions: current knowledge and future perspectives
Ronconi, V., Turchi, F., Bujalska, I. J., Giacchetti, G., & Boscaro, M. (2008) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2008.01.004 · Cited by 21
Paradoxical resistance to high-fat diet-induced obesity and altered macrophage polarization in mineralocorticoid receptor-overexpressing mice
Kuhn, E., Bourgeois, C., Keo, V., Viengchareun, S., Muscat, A., Méduri, G., Menuet, D. L., Fève, B., & Lombès, M. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00323.2013 · Cited by 23
Transgenic mouse models to study human mineralocorticoid receptor function in vivo
Menuet, D. L., Zennaro, M., Viengchareun, S., & Lombès, M. (2000) · Kidney International · doi:10.1046/j.1523-1755.2000.00966.x · Cited by 19
Skinfold thickness and blood pressure across C-344T polymorphism of CYP11B2 gene
Casiglia, E., Tikhonoff, V., Schiavon, L., Guglielmi, F., Pagnin, E., Bascelli, A., Basso, G., Mazza, A., Martini, B., Bolzon, M., et al. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e32826308a0 · Cited by 17
In vivo tissue specific modulation of rat insulin receptor gene expression in an experimental model of mineralocorticoid excess
Campión, J., Lahera, V., Cachofeiro, V., Maestro, B., Dávila, N., Carranza, M. C., & Calle, C. (1998) · Molecular and Cellular Biochemistry · doi:10.1023/a:1006871309864 · Cited by 18
Culture of embryonic renal collecting duct epithelia in a gradient container
Minuth, W. W., Aigner, J., Kloth, S., Steiner, P., Tauc, M., & Jennings, M. L. (1997) · Pediatric Nephrology · doi:10.1007/s004670050245 · Cited by 17
Role of RAAS and adipokines in cardiovascular protection: effect of different doses of angiotensin II receptor blocker on adipokines level in hypertensive patients
Hass, A., Oz, H., Mashavi, M., & Shargorodsky, M. (2014) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2014.07.033 · Cited by 14
Functional variability in corticosteroid receptors is a major component of strain differences in fat deposition and metabolic consequences of enriched diets in rat
Marissal‐Arvy, N., Langlois, A., Tridon, C., & Mormède, P. (2010) · Metabolism · doi:10.1016/j.metabol.2010.07.005 · Cited by 14
Estrogen stimulation of creatine kinase B specific activity in 3T3L1 adipocytes after their differentiation in culture: Dependence on estrogen receptor
Sömjen, D., Tordjman, K. M., Waisman, A., Mor, G., Amir-Zaltsman, Y., Kohen, F., & Kaye, A. M. (1997) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(97)00059-9 · Cited by 13
snRNA-seq of adipose tissues reveals the potential cellular and molecular mechanisms of cold and disease resistance in Mongolian cattle
Chi, Z., Jia, Q., Yang, H., Ren, H., Jin, C., He, J., Wuri, N., Sui, Z., Zhang, J., Mengke, B., et al. (2024) · BMC Genomics · doi:10.1186/s12864-024-10913-y · Cited by 12
Adipogenesis is under surveillance of Hsp90 and the high molecular weight Immunophilin FKBP51
Toneatto, J., Charó, N. L., Galigniana, N. M., & Piwien‐Pilipuk, G. (2015) · Adipocyte · doi:10.1080/21623945.2015.1049401 · Cited by 11
UCP1 transrepression in Brown Fat in vivo and mineralocorticoid receptor anti-thermogenic effects
Kuhn, E., Lamribet, K., Viengchareun, S., Menuet, D. L., Fève, B., & Lombès, M. (2018) · Annales d Endocrinologie · doi:10.1016/j.ando.2018.04.018 · Cited by 11
Role of NF?B in the regulation of macrophage colony stimulating factor by tumor necrosis factor-? in ST2 bone stromal cells
Isaacs, S. D., Fan, X., Fan, D., Gewant, H. D., Murphy, T. C., FARMER, P. K., Taylor, W. R., Nanes, M. S., & Rubin, J. E. (1999) · Journal of Cellular Physiology · doi:10.1002/(sici)1097-4652(199905)179:2 · Cited by 21
Adipogenesis and aldosterone: a study in lean tryptophan-depleted rats
Pokusa, M., Hlaváčová, N., Csanova, A., Franklin, M., Zórad, Š., & Ježová, D. (2016) · General Physiology and Biophysics · doi:10.4149/gpb_2016020 · Cited by 9
FK506 binding protein 51: Its role in the adipose organ and beyond
Galigniana, N. M., Ruiz, M. C., & Piwien‐Pilipuk, G. (2022) · Journal of Cellular Biochemistry · doi:10.1002/jcb.30351 · Cited by 10
The mineralocorticoid receptor: a new player controlling energy homeostasis
Kuhn, E., & Lombès, M. (2013) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2013-0033 · Cited by 10
Nonsteroidal mineralcorticoid receptor antagonists: Novel therapeutic implication in the management of patients with type 2 diabetes
Greco, E. A., Feraco, A., Marzolla, V., Mirabelli, M., Cimino, L., Armani, A., Brunetti, A., & Caprio, M. (2021) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2021.07.010 · Cited by 8
Increased Aldosterone: Mechanism of Hypertension in Obesity
Flynn, C. A. (2014) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2014.04.009 · Cited by 8
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism
Li, X., Luo, M., Zeng, Y., Zhang, R., Lin, X., Du, Y., Zhao, W., Feng, Q., Wu, M., Zhang, J., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06329-1 · Cited by 7
The invention of aldosterone, how the past resurfaces in pediatric endocrinology
Viengchareun, S., Pussard, E., Castanet, M., Sachs, L. M., Vu, T. A., Boileau, P., Lombès, M., & Martinerie, L. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111375 · Cited by 7
Association Between Renal Sinus Fat and Cardiometabolic and Renin-Angiotensin System Parameters in Primary Aldosteronism
Mitsuno, R., Kaneko, K., Nakamura, T., Kojima, D., Mizutani, Y., Azegami, T., Yamaguchi, S., Yamada, Y., Jinzaki, M., Kinouchi, K., et al. (2023) · Journal of the Endocrine Society · doi:10.1210/jendso/bvad154 · Cited by 7
Sex and depot-specific stimulation of creatine kinase B in rat adipose tissues by gonadal steroids
Sömjen, D., Lundgren, S., & Kaye, A. M. (1997) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(97)00011-3 · Cited by 7
The mineralocorticoid system, cardiometabolic health and its interplay with adipose tissue
Thuzar, M., Halim, M. A., & Stowasser, M. (2024) · Journal of Endocrinology · doi:10.1530/joe-24-0119 · Cited by 6
Adiponectin as an Independent Predictor of Left Ventricular Hypertrophy in Nondiabetic Patients With Hypertension
Peer, M., Mashavi, M., Matas, Z., Harpaz, D., & Shargorodsky, M. (2014) · Angiology · doi:10.1177/0003319714523332 · Cited by 4
Mineralocorticoid receptors, macrophages and new mechanisms for cardiovascular disease
Ho, Q. V., & Young, M. J. (2024) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2024.112340 · Cited by 3
[The dynamic mitochondria-nuclear redistribution of FKBP51 during the process of adipocyte differentiation is regulated by PKA].
Toneatto, J., Charó, N. L., Susperreguy, S., & Piwien‐Pilipuk, G. (2013) · PubMed · Cited by 2
Insulin signaling in adipose tissue of patients with primary aldosteronism
Urbanet, R., Pilon, C., Giorgino, F., Vettor, R., & Fallo, F. (2011) · Journal of Endocrinological Investigation · doi:10.1007/bf03347035 · Cited by 2
Corticosteroid Receptors, Their Chaperones and Cochaperones: How Do They Modulate Adipogenesis?
Toneatto, J., Charó, N. L., Naselli, A., Muñoz-Bernart, M., Lombardi, A., & Piwien‐Pilipuk, G. (2014) · Nuclear Receptor Research · doi:10.11131/2014/101092 · Cited by 1
The regulation of preadipocyte differentiation by glucocorticoids
Tomlinson, J. J. (2007) · uO Research (University of Ottawa) · doi:10.20381/ruor-13103
Studies on the function of the NGFIC subfamily of nuclear receptors in adipose tissue.
Wakes, N. C. (2006) · UCL Discovery (University College London)
Vers l’identification de nouveaux effets métaboliques du récepteur des minéralocorticoïdes
Fève, B. (2012) · Médecine des Maladies Métaboliques · doi:10.1016/s1957-2557(12)70395-4
Possible Interactions Among Fatty Acids, Other Lipids, and Aldosterone in the Hypertension of Obesity
Goodfriend, T. L. (1998) · Endocrine updates · doi:10.1007/978-1-4615-5569-8_17
Prevention of Adverse Metabolic Consequences of Adipocyte Dysfunction Using MR Antagonists
Caprio, M., Marzolla, V., & Armani, A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-805421-5.00007-0
Protein Tyrosine Phosphatase 1B Reduction Regulates Adiposity and Expression of Genes Involved in
Rondinone, L. M., Trevillyan, J. M., Clampit, J. E., Gum, R. J., Berg, C., Kroeger, P., Frost, L., Zinker, B. A., Reilly, R. M., Ulrich, R. G., et al. (2002)
Proatherogenic crosstalk between adipose tissue and smooth muscle cells
Schlich, R. (2012)
Mineralocorticoid Receptor in Novel Target Tissues: A Closer Look at the Adipocyte
Armani, A., Marzolla, V., Feraco, A., Gorini, S., Mammi, C., Infante, M., & Caprio, M. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.87231
Einfluss einer fettreichen Ernährung auf eine funktionelle Einzelniere mit den Risiko-Genvarianten COL4A3 +/- und NPHS +/R140Q im Mausmodell
Breier, K. (2022) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-9555
Metabolic effects of aldosterone
Валерьевна, И. К., Mazurina, N. V., Platonova, N. M., & Troshina, E. A. (2024) · Obesity and metabolism · doi:10.14341/omet13040 · Cited by 1
Salivary free aldosterone awakening response and cardiovascular risk in men with CHD, hypertension, and healthy controls
Gideon, A., von Känel, R., Degroote, C., Thomas, L., Zuccarella‐Hackl, C., Wiest, R., & Wirtz, P. H. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1655896
Perturbations du métabolisme glucidique et azoté dans des modèles d'obésité induite par le régime hyperlipidique ou par les glucocorticoïdes
Do, T. T. H. (2016) · theses.fr (ABES) · doi:10.70675/e2af6462zcab6z4ff3z9101z1ed9a75555cc
Rôle du récepteur adipocytaire des glucocorticoïdes dans les troubles métaboliques liés à un traitement par la corticostérone
Dalle, H. (2019) · theses.fr (ABES) · doi:10.70675/941a3a33za85bz426eza2b7zcf2c51460921
Implication du récepteur minéralocorticoïde adipeux dans les dysfonctions métaboliques et vasculaires associées à l’obésité et au syndrome métabolique : rôle des mitochondries
Lefranc, C. (2020) · theses.fr (ABES) · doi:10.70675/63bffb80z502cz4bdcz9729ze61518233589
Mineralocorticoid receptor genetics: A scoping review
Jaurretche, S. P. A., Balañá, C., & Bascolo, R. (2026) · World Journal of Medical Genetics · doi:10.5496/wjmg.115237

Authors: Rondinone, C. M., Rodbard, D., & Baker, M. E.
Affiliations: National Institutes of Health (US)
ORCID: Rodbard, D
Baker, M E
Venue: Endocrinology
Publisher: The Endocrine Society
Published: 1993-06
Volume: 132
Issue: 6
Pages: 2421-2426
ISSN: 0013-7227 (ISSN-L)
1945-7170
DOI: 10.1210/endo.132.6.8504747
OpenAlex: W2073760548
Cited by: 101
References: 3
Citations by year: 2026: 3 · 2025: 1 · 2024: 4 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 2 · 2019: 4 · 2018: 5 · 2017: 2 · 2016: 5 · 2015: 5 · 2014: 9 · 2013: 5 · 2012: 6
FWCI: 0.00
Type: journal article
Language: en
Open access: closed
Locations: Endocrinology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
Keywords: aldosterone, adipogenesis, 3T3-L1 cells, mineralocorticoid receptor, glucocorticoid receptor, steroid binding sites, triglycerides, glycerol-3-phosphate dehydrogenase, gene expression regulation
MeSH terms: Adipose Tissue, Aldosterone, Androstanols, Animals, Binding, Competitive, Cell Differentiation, Glycerolphosphate Dehydrogenase, Hydrocortisone, Receptors, Glucocorticoid, Spironolactone, Triglycerides, 3T3 Cells, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Aldosterone stimulated differentiation of mouse 3T3-L1 cells into adipocytes

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks