Obesity, sleep apnea, aldosterone, and hypertension

Abdominal Visceral and Subcutaneous Adipose Tissue Compartments: Association With Metabolic Risk Factors in the Framingham Heart Study

Fox, C. S., Massaro, J. M., Hoffmann, U., Pou, K. M., Maurovich-Horvat, P., Liu, C.-Y., Vasan, R. S., Murabito, J. M., Meigs, J. B., Cupples, L. A., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.675355 · Cited by 2,882 · see citing works

Pathophysiology of Sleep Apnea

Dempsey, J. A., Veasey, S. C., Morgan, B. J., & O'Donnell, C. P. (2010) · Physiological Reviews · doi:10.1152/physrev.00043.2008 · Cited by 2,243 · see citing works

Prognostic accuracy of day versus night ambulatory blood pressure: a cohort study

Boggia, J., Li, Y., Thijs, L., Hansen, T. W., Kikuya, M., Björklund-Bodegård, K., Richart, T., Ohkubo, T., Kuznetsova, T., Torp-Pedersen, C., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61538-4 · Cited by 887 · see citing works

The link between abdominal obesity, metabolic syndrome and cardiovascular disease

Ritchie, S. A., & Connell, J. M. C. (2006) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2006.07.005 · Cited by 725 · see citing works

Effect of Spironolactone on Blood Pressure in Subjects With Resistant Hypertension

Chapman, N., Dobson, J., Wilson, S. L., Dahlöf, B., Sever, P., Wedel, H., & Poulter, N. R. (2007) · Hypertension · doi:10.1161/01.hyp.0000259805.18468.8c · Cited by 630 · see citing works

Weight Loss and the Renin-Angiotensin-Aldosterone System

Engeli, S., Böhnke, J., Gorzelniak, K., Janke, J., Schling, P., Bäder, M., Luft, F. C., & Sharma, A. M. (2005) · Hypertension · doi:10.1161/01.hyp.0000154361.47683.d3 · Cited by 625 · see citing works

Obesity, Sleep Apnea, and Hypertension

Wolk, R., Shamsuzzaman, A. S. M., & Somers, V. K. (2003) · Hypertension · doi:10.1161/01.hyp.0000101686.98973.a3 · Cited by 532 · see citing works

Efficacy of low-dose spironolactone in subjects with resistant hypertension

Nishizaka, M. (2003) · American Journal of Hypertension · doi:10.1016/s0895-7061(03)01032-x · Cited by 500 · see citing works

The sympathetic nervous system and the metabolic syndrome

Mancia, G., Bousquet, P., Elghozi, J. L., Esler, M., Grassi, G., Julius, S., Reid, J., & Van Zwieten, P. A. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e328048d004 · Cited by 385 · see citing works

Plasma Aldosterone Is Related to Severity of Obstructive Sleep Apnea in Subjects With Resistant Hypertension

Pratt-Ubunama, M. N., Nishizaka, M. K., Boedefeld, R. L., Cofield, S. S., Harding, S. M., & Calhoun, D. A. (2007) · Chest · doi:10.1378/chest.06-1442 · Cited by 331 · see citing works

Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and Evidence From New Hypertension Trials

Jones, D. W., & Hall, J. E. (2003) · Hypertension · doi:10.1161/01.hyp.0000110061.06674.ca · Cited by 309 · see citing works

Resistant Hypertension, Obesity, Sleep Apnea, and Aldosterone: Theory and Therapy

Goodfriend, T. L., & Calhoun, D. A. (2004) · Hypertension · doi:10.1161/01.hyp.0000116223.97436.e5 · Cited by 279 · see citing works

Insulin Sensitivity in Patients with Primary Aldosteronism: A Follow-Up Study

Catena, C., Lapenna, R., Baroselli, S., Nadalini, E., Colussi, G., Novello, M., Favret, G., Melis, A., Cavarape, A., & Sechi, L. A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0736 · Cited by 262 · see citing works

Aldosterone Excretion Among Subjects With Resistant Hypertension and Symptoms of Sleep Apnea

Calhoun, D. A., Nishizaka, M. K., Zaman, M. A., & Harding, S. M. (2004) · Chest · doi:10.1378/chest.125.1.112 · Cited by 260 · see citing works

Regulation of 11β‐HSD Genes in Human Adipose Tissue: Influence of Central Obesity and Weight Loss

Engeli, S., Böhnke, J., Feldpausch, M., Gorzelniak, K., Heintze, U., Janke, J., Luft, F. C., & Sharma, A. M. (2004) · Obesity Research · doi:10.1038/oby.2004.3 · Cited by 211 · see citing works

Overexpression of 11β-Hydroxysteroid Dehydrogenase-1 in Adipose Tissue Is Associated with Acquired Obesity and Features of Insulin Resistance: Studies in Young Adult Monozygotic Twins

Kannisto, K., Pietiläinen, K. H., Ehrenborg, E., Rissanen, A., Kaprio, J., Hamsten, A., & Yki-Järvinen, H. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0153 · Cited by 205 · see citing works

Epoxy-Keto Derivative of Linoleic Acid Stimulates Aldosterone Secretion

Goodfriend, T. L., Ball, D. L., Egan, B. M., Campbell, W. B., & Nithipatikom, K. (2004) · Hypertension · doi:10.1161/01.hyp.0000113294.06704.64 · Cited by 205 · see citing works

The role of spironolactone in the treatment of patients with refractory hypertension

Ouzan, J. M., Perault, C., Lincoff, A. M., Carre, E., & Mertès, P. (2002) · American Journal of Hypertension · doi:10.1016/s0895-7061(01)02342-1 · Cited by 203 · see citing works

Differing Pattern of Sympathoexcitation in Normal-Weight and Obesity-Related Hypertension

Lambert, E., Straznicky, N., Schlaich, M., Esler, M., Dawood, T., Hotchkin, E., & Lambert, G. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.094649 · Cited by 195 · see citing works

Gender Differences in Sleep Apnea

Dancey, D. R., Hanly, P. J., Soong, C., Lee, B., Shepard, J., & Hoffstein, V. (2003) · CHEST Journal · doi:10.1378/chest.123.5.1544 · Cited by 189 · see citing works

Effects of Continuous Positive Airway Pressure Versus Supplemental Oxygen on 24-Hour Ambulatory Blood Pressure

Norman, D., Loredo, J. S., Nelesen, R. A., Ancoli‐Israel, S., Mills, P. J., Ziegler, M. G., & Dimsdale, J. E. (2006) · Hypertension · doi:10.1161/01.hyp.0000217128.41284.78 · Cited by 187 · see citing works

Salt-Induced Nephropathy in Obese Spontaneously Hypertensive Rats Via Paradoxical Activation of the Mineralocorticoid Receptor

Nagase, M., Matsui, H., Shibata, S., Gotoda, T., & Fujita, T. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.091058 · Cited by 157 · see citing works

Leptin, obesity and cardiovascular disease

Correia, M., & Haynes, W. G. (2004) · Current Opinion in Nephrology & Hypertension · doi:10.1097/00041552-200403000-00010 · Cited by 153 · see citing works

Aldosterone in obesity

Goodfriend, T. L., Egan, B. M., & Kelley, D. E. (1998) · Endocrine Research · doi:10.3109/07435809809032689 · Cited by 144 · see citing works

Aldosterone Suppresses Insulin Signaling Via the Downregulation of Insulin Receptor Substrate-1 in Vascular Smooth Muscle Cells

Hitomi, H., Kiyomoto, H., Nishiyama, A., Hara, T., Moriwaki, K., Kaifu, K., Ihara, G., Fujita, Y., Ugawa, T., & Kohno, M. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.093955 · Cited by 140 · see citing works

11β‐HSD Type 1 Expression in Human Adipose Tissue: Impact of Gender, Obesity, and Fat Localization

Paulsen, S. K., Pedersen, S. B., Fisker, S., & Richelsen, B. (2007) · Obesity · doi:10.1038/oby.2007.233 · Cited by 136 · see citing works

Effects of treatment with nasal continuous positive airway pressure on atrial natriuretic peptide and arginine vasopressin release during sleep in patients with obstructive sleep apnoea

Krieger, J., FOLLENIUS, M., Sforza, É., et al. (1991) · Clinical Science · doi:10.1042/cs0800443 · Cited by 121 · see citing works

Renin and aldosterone are higher and the hyperinsulinemic effect of salt restriction greater in subjects with risk factors clustering.

Egan, B. M., Stepniakowski, K., & Goodfriend, T. L. (1994) · PubMed · doi:10.1016/0895-7061(94)p1710-h · Cited by 114 · see citing works

Role for aldosterone in blood pressure regulation of obese adolescents

Rocchini, A. P., Katch, V. L., Grekin, R. J., Moorehead, C., & Anderson, J. (1986) · The American Journal of Cardiology · doi:10.1016/0002-9149(86)90845-3 · Cited by 112 · see citing works

Salt-regulating hormones in young normotensive obese subjects. Effects of saline load.

Licata, G., Volpe, M., Scaglione, R., & Rubattu, S. (1994) · Hypertension · doi:10.1161/01.hyp.23.1_suppl.i20 · Cited by 107 · see citing works

Aldosterone stimulated differentiation of mouse 3T3-L1 cells into adipocytes

Rondinone, C. M., Rodbard, D., & Baker, M. E. (1993) · Endocrinology · doi:10.1210/endo.132.6.8504747 · Cited by 101 · see citing works

Relationships Among Plasma Aldosterone, High-Density Lipoprotein Cholesterol, and Insulin in Humans

Goodfriend, T. L., Egan, B. M., Stepniakowski, K. T., & Ball, D. L. (1995) · Hypertension · doi:10.1161/01.hyp.25.1.30 · Cited by 98 · see citing works

The Contribution of Visceral Adipose Tissue to Splanchnic Cortisol Production in Healthy Humans

Andrew, R., Westerbacka, J., Wahren, J., Yki‐Järvinen, H., & Walker, B. R. (2005) · Diabetes · doi:10.2337/diabetes.54.5.1364 · Cited by 98 · see citing works

The Effect of Correction of Sleep-Disordered Breathing on BP in Untreated Hypertension

Hla, K. M., Skatrud, J. B., Finn, L. A., Palta, M., & Young, T. B. (2002) · CHEST Journal · doi:10.1378/chest.122.4.1125 · Cited by 95 · see citing works

Renin and Aldosterone Are Higher and the Hyperinsulinemic Effect of Salt Restriction Greater in Subjects With Risk Factors Clustering

Egan, B. M., Stepniakowski, K. T., & Goodfriend, T. L. (1994) · American Journal of Hypertension · doi:10.1093/ajh/7.10.886 · Cited by 94 · see citing works

Adipocyte-derived products induce the transcription of the StAR promoter and stimulate aldosterone and cortisol secretion from adrenocortical cells through the Wnt-signaling pathway

Schinner, S., Willenberg, H. S., Krause, D., Schott, M., Lamounier‐Zepter, V., Krug, A. W., Ehrhart‐Bornstein, M., Bornstein, S. R., & Scherbaum, W. A. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803508 · Cited by 89 · see citing works

Hypertension and the Metabolic Syndrome

Morse, S. A., Zhang, R., Thakur, V., & Reisin, E. (2005) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200512000-00008 · Cited by 88 · see citing works

Salt-Sensitive Blood Pressure in Mice With Increased Expression of Aldosterone Synthase

Makhanova, N., Hagaman, J. R., Kim, H., et al. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.098897 · Cited by 75 · see citing works

Efficacy of Add-On Aldosterone Receptor Blocker in Uncontrolled Hypertension

Sharabi, Y., Adler, E., SHAMIS, A., Nussinovitch, N., MARKOVITZ, A., & Grossman, E. (2006) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2005.11.016 · Cited by 68 · see citing works

Changes in Endocrine Activities Relative to Obesity in Patients with Essential Hypertension*

Hiramatsu, K., Yamada, T., Ichikawa, K., Izumiyama, T., & Nagata, H. (1981) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1981.tb02389.x · Cited by 55 · see citing works

Regulation of adrenal steroidogenesis during chronic stress

Aguilera, G., Kiss, A., Lu, A., & Camacho, C. (1996) · Endocrine Research · doi:10.1080/07435809609043729 · Cited by 53 · see citing works

The Association of Aldosterone With Obesity-Related Hypertension and the Metabolic Syndrome

Vogt, B., Bochud, M., & Burnier, M. (2007) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2007.07.009 · Cited by 47 · see citing works

Dynamic analysis of patterns of renal sympathetic nerve activity: implications for renal function

DiBona, G. F. (2004) · Experimental Physiology · doi:10.1113/expphysiol.2004.029215 · Cited by 30 · see citing works

Aldosterone—A Hormone of Cardiovascular Adaptation and Maladaptation

Goodfriend, T. L. (2006) · Journal of Clinical Hypertension · doi:10.1111/j.1524-6175.2006.05110.x · Cited by 28 · see citing works

Aldosterone

Adler, G. K., & Williams, G. H. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.090894 · Cited by 22 · see citing works

Treating resistant hypertension in type 2 diabetes: a role for spironolactone?

Stanley, A. G., Swales, P., Thurston, H., et al. (2006) · The British Journal of Diabetes · doi:10.1177/14746514060060020701 · Cited by 5 · see citing works

Obesity‐Related Hypertension: Pathogenesis, Cardiovascular Risk, and Treatment: A Position Paper of <i>The Obesity Society</i> and the <i>American Society of Hypertension</i>

Landsberg, L., Aronne, L. J., Beilin, L. J., Burke, V., Igel, L. I., Lloyd‐Jones, D., & Sowers, J. (2013) · The Journal of Clinical Hypertension · doi:10.1111/jch.12049 · Cited by 528 · see citing works

The Cost of Poor Sleep: Workplace Productivity Loss and Associated Costs

Rosekind, M. R., Gregory, K. B., Mallis, M. M., Brandt, S. L., Seal, B., & Lerner, D. (2010) · Journal of Occupational &amp; Environmental Medicine · doi:10.1097/jom.0b013e3181c78c30 · Cited by 385 · see citing works

Renin-angiotensin-aldosterone system in patients with sleep apnoea: prevalence of primary aldosteronism

Di Murro, A., Petramala, L., Cotesta, D., Zinnamosca, L., Crescenzi, E., Marinelli, C., Saponara, M., & Letizia, C. (2010) · Journal of the Renin-Angiotensin-Aldosterone System · doi:10.1177/1470320310366581 · Cited by 125 · see citing works

Elevated plasma aldosterone levels are associated with a reduction in retinal ganglion cell survival

Takasago, Y., Hirooka, K., Nakano, Y., Kobayashi, M., & Ono, A. (2018) · Journal of the Renin-Angiotensin-Aldosterone System · doi:10.1177/1470320318795001 · Cited by 17 · see citing works

Discussion on pathogenesis levels of hypertension

Wang, Q. (2007) · Zhongyi-yao xuebao

Prolonged oral administration of potassium upon aldosterone biosynthesis by rat glomerulosa tissue in vitro.

Regöly-Mérei, J., & Sólyom, J. (1975) · PubMed · Cited by 1 · see citing works

Different effects of three aldosterone treatments on plasma aldosterone and salt intake

Tordoff, M. G., Hughes, R. L., & Pilchak, D. M. (1993) · Physiology & Behavior · doi:10.1016/0031-9384(93)90054-j · Cited by 11 · see citing works

EFFECT OF POTASSIUM DEFICIENCY UPON THE FINAL STEPS OF ALDOSTERONE BIOSYNTHESIS IN THE RAT

Baumann, K., & Müller, J. (1971) · European Journal of Endocrinology · doi:10.1530/acta.0.067s109 · Cited by 2 · see citing works