The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Expanding the Scales: The Multiple Roles of MCH in Regulating Energy Balance and Other Biological Functions
Abstract
Melanin-concentrating hormone (MCH) is a cyclic peptide originally identified as a 17-amino-acid circulating hormone in teleost fish, where it is secreted by the pituitary in response to stress and environmental stimuli. In fish, MCH lightens skin color by stimulating aggregation of melanosomes, pigment-containing granules in melanophores, cells of neuroectodermal origin found in fish scales. Although the peptide structure between fish and mammals is highly conserved, in mammals, MCH has no demonstrable effects on pigmentation; instead, based on a series of pharmacological and genetic experiments, MCH has emerged as a critical hypothalamic regulator of energy homeostasis, having effects on both feeding behavior and energy expenditure.
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Cites
Leptin and the regulation of body weight in mammals
Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405
Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
Thornton, J. E., Cheung, C. C., Clifton, D. K., & Steiner, R. A. (1997) · Endocrinology · doi:10.1210/endo.138.11.5651 · Cited by 437
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Berbari, N. F., Lewis, J. S., Bishop, G. A., Askwith, C. C., & Mykytyn, K. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711027105 · Cited by 474
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Metadata
- Authors
- Pissios, P., Bradley, R. L., & Maratos-Flier, E.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 2006-06-20
- Volume
- 27
- Issue
- 6
- Pages
- 606-620
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2033915786
- Cited by
- 205
- References
- 2
- FWCI
- 6.98
- Type
- journal article
- Language
- en
- Open access
- closed
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