The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
What Can We Learn from Rodents about Prolactin in Humans?
Open accessAbstract
Prolactin (PRL) is a 23-kDa protein hormone that binds to a single-span membrane receptor, a member of the cytokine receptor superfamily, and exerts its action via several interacting signaling pathways.PRL is a multifunctional hormone that affects multiple reproductive and metabolic functions and is also involved in tumorigenicity.In addition to being a classical pituitary hormone, PRL in humans is produced by many tissues throughout the body where it acts as a cytokine.The objective of this review is to compare and contrast multiple aspects of PRL, from structure to regulation, and from physiology to pathology in rats, mice, and humans.At each juncture, questions are raised whether, or to what extent, data from rodents are relevant to PRL homeostasis in humans.Most current knowledge on PRL has been obtained from studies with rats and, more recently, from the use of transgenic mice.Although this information is indispensable for understanding PRL in human health and disease, there is sufficient disparity in the control of the production, distribution, and physiological functions of PRL among these species to warrant careful and judicial extrapolation to humans.(Endocrine Reviews 29: 1-41, 2008) I. Introduction II.The PRL Gene A. Overview of the PRL/GH/PL family B. Regulation of PRL gene expression III.PRL Proteins A. Structural characteristics IV.PRL Receptors and Signaling A. Structure-function relationship B. Signaling pathways V. PRL Release A. Regulation of pituitary PRL release B. Regulation of extrapituitary PRL release VI.PRL Functions: Reproduction A. Reproductive cycles B
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Adipose Tissue as an Endocrine Organ
Ahima, R. S., & Flier, J. S. (2000) · Trends in Endocrinology & Metabolism · doi:10.1016/s1043-2760(00)00301-5 · Cited by 1,608
Dopamine as a Prolactin (PRL) Inhibitor
Ben-Jonathan, N., & Hnasko, R. (2001) · Endocrine Reviews · doi:10.1210/edrv.22.6.0451 · Cited by 983
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Half a century of antipsychotics and still a central role for dopamine D2 receptors
Kapur, S., & Mamo, D. (2003) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2003.09.004 · Cited by 638
Antipsychotic-Induced Hyperprolactinaemia: Mechanisms, Clinical Features and Management
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Identification of a heparin-binding motif on adeno-associated virus type 2 capsids
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Reflections on the Discovery and Significance of Estrogen Receptor β
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Self-citationAnterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter
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Sexual function of the ageing male
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Kisspeptin regulates prolactin release through hypothalamic dopaminergic neurons
Szawka, R. E., Ribeiro, A. B., Leite, C. M., Helena, C. V. V., Franci, C. R., Anderson, G. M., Hoffman, G. E., & Anselmo-Franci, J. A. (2010) · Endocrinology · doi:10.1210/en.2009-1414 · Cited by 97
Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period
Auffret, J., Freemark, M., Carré, N., Mathieu, Y., Tourrel-Cuzin, C., Lombès, M., Movassat, J., & Binart, N. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00636.2012 · Cited by 46
Ledesma-Colunga, M. G., Adán, N., Ortiz, G., Solís-Gutiérrez, M., López-Barrera, F., Martínez de la Escalera, G., & Clapp, C. (2017) · Arthritis Research & Therapy · doi:10.1186/s13075-017-1290-4 · Cited by 40
Metadata
- Authors
- Ben-Jonathan, N., LaPensee, C. R., & LaPensee, E. W.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 2007-12-05
- Volume
- 29
- Issue
- 1
- Pages
- 1-41
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2164875032
- Cited by
- 523
- References
- 15
- FWCI
- 15.93
- Type
- journal article
- Language
- en
- Open access
- bronze
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