The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update
Abstract
Acromegaly is a chronic systemic disease with many complications and is associated with increased mortality when not adequately treated. Substantial advances in acromegaly treatment, as well as in the treatment of many of its complications, mainly diabetes mellitus, heart failure, and arterial hypertension, were achieved in the last decades. These developments allowed change in both prevalence and severity of some acromegaly complications and furthermore resulted in a reduction of mortality. Currently, mortality seems to be similar to the general population in adequately treated patients with acromegaly. In this review, we update the knowledge in complications of acromegaly and detail the effects of different acromegaly treatment options on these complications. Incidence of mortality, its correlation with GH (cumulative exposure vs last value), and IGF-I levels and the shift in the main cause of mortality in patients with acromegaly are also addressed.
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Cited by
Insulin-Like Growth Factor 1 (IGF-1) Signaling in Glucose Metabolism in Colorectal Cancer
Kasprzak, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126434 · Cited by 248
Tchkonia, T., Palmer, A. K., & Kirkland, J. L. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa728 · Cited by 129
Metadata
- Authors
- Gadelha, M. R., Kasuki, L., Lim, D. S. T., & Fleseriu, M.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 2018-08-31
- Volume
- 40
- Issue
- 1
- Pages
- 268-332
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2889103264
- Cited by
- 363
- References
- 42
- FWCI
- 20.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update. https://app.cochat.ai/papers/10.1210/er.2018-00115
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- Gadelha, M. R., Kasuki, L., Lim, D. S. T., & Fleseriu, M. (2019). Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update. Endocrine Reviews. https://doi.org/10.1210/er.2018-00115
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
