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Cited by 363

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update

Gadelha, Mônica R, Kasuki, Leandro, Lim, Dawn S T, Fleseriu, Maria·2019·Endocrine Reviews
DOI 10.1210/er.2018-00115
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Abstract

Acromegaly is a chronic systemic disease with many complications and is associated with increased mortality when not adequately treated. Substantial advances in acromegaly treatment, as well as in the treatment of many of its complications, mainly diabetes mellitus, heart failure, and arterial hypertension, were achieved in the last decades. These developments allowed change in both prevalence and severity of some acromegaly complications and furthermore resulted in a reduction of mortality. Currently, mortality seems to be similar to the general population in adequately treated patients with acromegaly. In this review, we update the knowledge in complications of acromegaly and detail the effects of different acromegaly treatment options on these complications. Incidence of mortality, its correlation with GH (cumulative exposure vs last value), and IGF-I levels and the shift in the main cause of mortality in patients with acromegaly are also addressed.

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Metadata

Authors
Gadelha, M. R., Kasuki, L., Lim, D. S. T., & Fleseriu, M.
Venue
Endocrine Reviews
Publisher
The Endocrine Society
Published
2018-08-31
Volume
40
Issue
1
Pages
268-332
ISSN
  • 0163-769X (ISSN-L)
  • 1945-7189
DOI
10.1210/er.2018-00115
OpenAlex
W2889103264
Cited by
363
References
42
FWCI
20.30
Type
journal article
Language
en
Open access
closed

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.