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Cited by 214

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Ghrelin Secretion in Humans Is Sexually Dimorphic, Suppressed by Somatostatin, and Not Affected by the Ambient Growth Hormone Levels

Open access
Barkan, Ariel L., Dimaraki, Eleni V., Jessup, Stacy K., Symons, Kathleen V., Ermolenko, Mikhail, Jaffe, Craig A.·2003·The Journal of Clinical Endocrinology & Metabolism
DOI 10.1210/jc.2002-021169
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Abstract

We studied plasma ghrelin and GH concentrations over a 24-h period in young healthy men and women and in patients with acromegaly. Healthy subjects were restudied after administration of GH-lowering agents, octreotide or GHRH antagonist. Ghrelin concentrations in women studied during the late follicular stage of the cycle were about 3-fold higher than in men. Suppression of GH secretion by GHRH antagonist did not alter ghrelin concentration profiles. In the presence of high GH levels (acromegaly), ghrelin levels were similar to those found in healthy men. Administration of somatostatin analog octreotide suppressed both GH and ghrelin concentration profiles. We conclude that: 1) ghrelin secretion is sexually dimorphic in humans, with women in the late follicular stage having higher levels than men; 2) ghrelin secretion is suppressed by somatostatin; and 3) GH has no influence over ghrelin secretion.

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Metadata

Authors
Barkan, A. L., Dimaraki, E. V., Jessup, S. K., Symons, K. V., Ermolenko, M., & Jaffe, C. A.
Venue
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Published
2003-05
Volume
88
Issue
5
Pages
2180-2184
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
DOI
10.1210/jc.2002-021169
OpenAlex
W2006011837
Cited by
214
References
6
FWCI
10.00
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Ghrelin Secretion in Humans Is Sexually Dimorphic, Suppressed by Somatostatin, and Not Affected by the Ambient Growth Hormone Levels. https://app.cochat.ai/papers/10.1210/jc.2002-021169
The paper
Barkan, A. L., Dimaraki, E. V., Jessup, S. K., Symons, K. V., Ermolenko, M., & Jaffe, C. A. (2003). Ghrelin Secretion in Humans Is Sexually Dimorphic, Suppressed by Somatostatin, and Not Affected by the Ambient Growth Hormone Levels. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jc.2002-021169

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.