A High Aldosterone to Renin Ratio Is Associated With High Serum Parathyroid Hormone Concentrations in the General Population
Abstract
CONTEXT: Activation of the renin-angiotensin-aldosterone system (RAAS) is associated with high serum PTH concentrations and vice versa. OBJECTIVE: The aim of this study was to analyze the associations of the plasma aldosterone concentration (PAC), the plasma renin concentration (PRC), or the aldosterone to renin ratio (ARR) with serum PTH concentrations in a sample from the general population of northeast Germany. DESIGN: We selected 3105 subjects (25-88 y) from the first 5-year follow-up examination of the Study of Health in Pomerania. The associations of PAC, PRC, or ARR with serum PTH concentrations were examined with multivariable linear regression analyses. We further calculated adjusted mean serum PTH concentrations according to PAC, PRC, and ARR categories (≥90th and < 90th sex specific percentiles and sex specific quartiles). The models were adjusted for age, sex, estimated glomerular filtration rate, serum 25-hydroxy vitamin D concentration, waist circumference, body mass index, hypertension, diabetes mellitus, liver disease, and intake of drugs that affect the RAAS or bone metabolism. RESULTS: We found no associations between PAC or PRC and serum PTH concentrations in fully adjusted linear regression models. However, fully adjusted linear regression and ANOVA models revealed higher serum PTH concentrations in subjects with an ARR 90th percentile or greater than in subjects with a lower ARR. CONCLUSIONS: Our data show that a high ARR is associated with high serum PTH concentrations in the general population and thus add to the increasing evidence of a relation between the RAAS and PTH.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Cites
The metabolic syndrome—a new worldwide definition
Alberti, K. G. M., Zimmet, P., & Shaw, J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67402-8 · Cited by 9,352 · see citing works
(2000) · Journal of the American Society of Nephrology · Cited by 1,718 · see citing works
Funder, J. W., Carey, R. M., Fardella, C., Gomez-Sanchez, C. E., Mantero, F., Stowasser, M., Young, W. F., & Montori, V. M. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0104 · Cited by 1,554 · see citing works
Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism
Milliez, P., Girerd, X. J., Plouin, P., Blacher, J., Safar, M. E., & Mourad, J. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.01.015 · Cited by 1,541 · see citing works
Cohort Profile: The Study of Health in Pomerania
Völzke, H., Alte, D., Schmidt, C. O., Radke, D., Lorbeer, R., Friedrich, N., Aumann, N., Lau, K., Piontek, K., Born, G., et al. (2010) · International Journal of Epidemiology · doi:10.1093/ije/dyp394 · Cited by 992 · see citing works
Self-citationCardiovascular Outcomes in Patients With Primary Aldosteronism After Treatment
Catena, C. (2008) · Archives of Internal Medicine · doi:10.1001/archinternmed.2007.33 · Cited by 566 · see citing works
Plasma Parathyroid Hormone and the Risk of Cardiovascular Mortality in the Community
Hagström, E., Hellman, P., Larsson, T. E., Ingelsson, E., Berglund, L., Sundström, J., Melhus, H., Held, C., Lind, L., Michaëlsson, K., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.808733 · Cited by 416 · see citing works
Hannemann, A., & Wallaschofski, H. (2011) · Hormone and Metabolic Research · doi:10.1055/s-0031-1295438 · Cited by 339 · see citing works
Self-citationObservational Study Mortality in Treated Primary Aldosteronism
Reincke, M., Fischer, E., Gerum, S., Merkle, K., Schulz, S., Pallauf, A., Quinkler, M. O., Hanslik, G., Lang, K., Hahner, S., et al. (2012) · Hypertension · doi:10.1161/hypertensionaha.112.197111 · Cited by 279 · see citing works
Self-citationCardiovascular Events before and after Surgery for Primary Hyperparathyroidism
Vestergaard, P., Mollerup, C., Frøkjær, V. G., Christiansen, P., Blichert-Toft, M., & Mosekilde, L. (2003) · World Journal of Surgery · doi:10.1007/s00268-002-6541-z · Cited by 180 · see citing works
Tomaschitz, A., Pilz, S., Ritz, E., Meinitzer, A., Boehm, B. O., & Marz, W. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq019 · Cited by 171 · see citing works
Pilz, S., Tomaschitz, A., Drechsler, C., Ritz, E., Boehm, B. O., Grammer, T. B., & Marz, W. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq109 · Cited by 160 · see citing works
Anderson, J. L., Vanwoerkom, R. C., Horne, B. D., Bair, T. L., May, H. T., LAPPE, D. L., & Muhlestein, J. B. (2011) · American Heart Journal · doi:10.1016/j.ahj.2011.05.005 · Cited by 155 · see citing works
Heart Failure Is a Risk Factor for Orthopedic Fracture
van Diepen, S., Majumdar, S. R., Bakal, J. A., McAlister, F. A., & Ezekowitz, J. A. (2008) · Circulation · doi:10.1161/circulationaha.108.784009 · Cited by 148 · see citing works
Rossi, E., Sani, C., Perazzoli, F., Casoli, M. C., Negro, A., & Dotti, C. (1995) · American Journal of Hypertension · doi:10.1016/0895-7061(95)00182-o · Cited by 134 · see citing works
Aldosterone and parathyroid hormone: a precarious couple for cardiovascular disease
Tomaschitz, A., Ritz, E., Pieske, B. M., Fahrleitner‐Pammer, A., Kienreich, K., Horina, J. H., Drechsler, C., März, W., Ofner, M., Pieber, T. R., et al. (2012) · Cardiovascular Research · doi:10.1093/cvr/cvs092 · Cited by 129 · see citing works
PTH and PTH-related peptide enhance steroid secretion from human adrenocortical cells
Mazzocchi, G., Aragona, F., Malendowicz, L. K., & Nussdorfer, G. G. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.280.2.e209 · Cited by 123 · see citing works
Pilz, S., Kienreich, K., Drechsler, C., Ritz, E., Fahrleitner-Pammer, A., Gaksch, M., Meinitzer, A., März, W., Pieber, T. R., & Tomaschitz, A. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-2183 · Cited by 118 · see citing works
Calcium metabolism and parathyroid function in primary aldosteronism
Resnick, L. M., & Laragh, J. H. (1985) · The American Journal of Medicine · doi:10.1016/0002-9343(85)90328-6 · Cited by 111 · see citing works
Bone involvement in aldosteronism
Salcuni, A. S., Palmieri, S., Carnevale, V., Morelli, V., Battista, C., Guarnieri, V., Guglielmi, G., Desina, G., Eller-Vainicher, C., Beck-Peccoz, P., et al. (2012) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1660 · Cited by 101 · see citing works
Primary Hyperparathyroidism With Concurrent Primary Aldosteronism
Maniero, C., Fassina, A., Guzzardo, V., Lenzini, L., Amadori, G., Pelizzo, M. R., Gomez-Sanchez, C., & Rossi, G. P. (2011) · Hypertension · doi:10.1161/hypertensionaha.111.173948 · Cited by 94 · see citing works
Mild hyperparathyroidism: a novel surgically correctable feature of primary aldosteronism
Maniero, C., Fassina, A., Seccia, T. M., Toniato, A., Iacobone, M., Plebani, M., De Caro, R., Calò, L. A., Pessina, A. C., & Rossi, G. P. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e32834f0451 · Cited by 87 · see citing works
Cardiovascular disease, hypertension and renal function in primary hyperparathyroidism
Hedbäck, G., & Odén, A. (2002) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2002.00984.x · Cited by 85 · see citing works
Bone health and aldosterone excess
Ceccoli, L., Ronconi, V., Giovannini, L., Marcheggiani, M., Turchi, F., Boscaro, M., & Giacchetti, G. (2013) · Osteoporosis International · doi:10.1007/s00198-013-2399-1 · Cited by 85 · see citing works
Brunaud, L., Germain, A., Zarnegar, R., Rancier, M., Alrasheedi, S., Caillard, C., Ayav, A., Weryha, G., Mirallie, E., & Bresler, L. (2009) · Surgery · doi:10.1016/j.surg.2009.09.041 · Cited by 83 · see citing works
Interrelationships between the renin-angiotensin-aldosterone and calcium homeostatic systems
Grant, F. D., Mandel, S. J., Brown, E. M., Williams, G. H., & Seely, E. W. (1992) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.75.4.1400892 · Cited by 76 · see citing works
Primary Aldosteronism and Metabolic Syndrome
Fallo, F., Pilon, C., & Urbanet, R. (2011) · Hormone and Metabolic Research · doi:10.1055/s-0031-1295412 · Cited by 75 · see citing works
ISALES, C. M., BARRETT, P. Q., BRINES, M., BOLLAG, W., & RASMUSSEN, H. (1991) · Endocrinology · doi:10.1210/endo-129-1-489 · Cited by 72 · see citing works
Kovacs, L., Goth, M., Szabolcs, I., Dohan, O., Ferencz, A., & Szilagyi, G. (1998) · European Journal of Endocrinology · doi:10.1530/eje.0.1380543 · Cited by 66 · see citing works
Gupta, M., Cheung, C., Hsu, Y., Demissie, S., Cupples, L. A., Kiel, D. P., & Karasik, D. (2011) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.333 · Cited by 62 · see citing works
Secondary Hyperparathyroidism in Patients with Untreated and Treated Congestive Heart Failure
Khouzam, R. N., Weber, K. T., Flax, S. D., Dishmon, D. A., Farah, V., & Carbone, L. D. (2006) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200601000-00009 · Cited by 54 · see citing works
Response of adrenal cells to parathyroid hormone stimulation
Rosenberg, J., Pines, M., & Hurwitz, S. (1987) · Journal of Endocrinology · doi:10.1677/joe.0.1120431 · Cited by 53 · see citing works
Hypertension Secondary to PHPT: Cause or Coincidence?
Schiffl, H., & Lang, S. M. (2011) · International Journal of Endocrinology · doi:10.1155/2011/974647 · Cited by 51 · see citing works
Calcium intake and risk of primary hyperparathyroidism in women: prospective cohort study
Paik, J. M., Curhan, G. C., & Taylor, E. N. (2012) · BMJ · doi:10.1136/bmj.e6390 · Cited by 46 · see citing works
Primary hyperparathyroidism in a patient with Conn’s syndrome
Fertig, A., Webley, M., & Lynn, J. (1980) · Postgraduate Medical Journal · doi:10.1136/pgmj.56.651.45 · Cited by 44 · see citing works
Renin-angiotensin-aldosterone system in primary hyperparathyroidism before and after surgery
Bernini, G., Moretti, A., Lonzi, S., Bendinelli, C., Miccoli, P., & Salvetti, A. (1999) · Metabolism · doi:10.1016/s0026-0495(99)90075-6 · Cited by 40 · see citing works
Primary hyperparathyroidism associated with primary hyperaldosteronism
Ferriss, J. B., Brown, J. J., Cumming, A. M. M., Fräser, R., Lever, A. F., Peacock, M., & Robertson, J. I. S. (1983) · European Journal of Endocrinology · doi:10.1530/acta.0.1030365 · Cited by 27 · see citing works
Stimulation of chick adrenal steroidogenesis by avian parathyroid hormone
Rosenberg, J., Pines, M., & Hurwitz, S. (1988) · Journal of Endocrinology · doi:10.1677/joe.0.1160091 · Cited by 27 · see citing works
Primary Hyperparathyroidism: Possible Cause of Primary Hyperaldosteronism in a 60-Year-Old Woman*
Barkan, A., Marilus, R., Winkelsberg, G., Yeshurun, D., & Blum, I. (1980) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-51-1-144 · Cited by 27 · see citing works
Aldosterone and Parathyroid Hormone: A Complex and Clinically Relevant Relationship
Pilz, S., Tomaschitz, A., März, W., Cavalier, E., & Ritz, E. (2010) · Calcified Tissue International · doi:10.1007/s00223-010-9409-5 · Cited by 21 · see citing works
Adrenal responses to subtotal parathyroidectomy for primary hyperparathyroidism
Pacifici, R., Perry, H. M., Shieber, W., Biglieri, E., Droke, D. M., & Avioli, L. V. (1987) · Calcified Tissue International · doi:10.1007/bf02563790 · Cited by 19 · see citing works
Øgard, C. G., Søndergaard, S. B., Vestergaard, H., Jakobsen, H. L., & Nielsen, S. L. (2005) · World Journal of Surgery · doi:10.1007/s00268-005-7740-1 · Cited by 9 · see citing works
Özata, M., Durmus, O., Yılmaz, M. İ., Bolu, E., Erdogan, M., & Ozdemír, I. C. (2002) · PubMed · Cited by 5 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The renin–angiotensin–aldosterone system and calcium-regulatory hormones
Vaidya, A., Brown, J. M., & Williams, J. S. (2015) · Journal of Human Hypertension · doi:10.1038/jhh.2014.125 · Cited by 93 · see citing works
Brown, J., de Boer, I. H., Robinson-Cohen, C., Siscovick, D. S., Kestenbaum, B., Allison, M., & Vaidya, A. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-3949 · Cited by 71 · see citing works
The Interplay Between the Renin-Angiotensin-Aldosterone System and Parathyroid Hormone
Zheng, M.-H., Li, F., Xu, F., Lin, X., Wang, Y., Xu, Q.-S., Guo, B., & Yuan, L. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00539 · Cited by 67 · see citing works
Primary Aldosteronism as a Risk Factor for Vertebral Fracture
Notsu, M., Yamauchi, M., Yamamoto, M., Nawata, K., & Sugimoto, T. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3206 · Cited by 51 · see citing works
Kontogeorgos, G., Trimpou, P., Laine, C. M., Oleröd, G., Lindahl, A. H., & Landin‐Wilhelmsen, K. (2015) · Clinical Endocrinology · doi:10.1111/cen.12819 · Cited by 48 · see citing works
Interrelated aldosterone and parathyroid hormone mutually modify cardiovascular mortality risk
Tomaschitz, A., Pilz, S., Rus-Machan, J., Meinitzer, A., Brandenburg, V. M., Scharnagl, H., Kapl, M., Grammer, T., Ritz, E., Horina, J. H., et al. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.03.062 · Cited by 27 · see citing works
Bayomy, O. F., Zaheer, S., Williams, J. S., Curhan, G. C., & Vaidya, A. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa123 · Cited by 27 · see citing works
Asbach, E., Bekeran, M., König, A., Lang, K., Hanslik, G., Treitl, M., Ladurner, R., Bidlingmaier, M., Beuschlein, F., Quinkler, M., et al. (2020) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-1027-6472 · Cited by 25 · see citing works
Self-citationVerheyen, N., Fahrleitner-Pammer, A., Pieske, B., Meinitzer, A., Belyavskiy, E., Wetzel, J., Gaksch, M., Grübler, M. R., Catena, C., Sechi, L. A., et al. (2016) · Journal of Hypertension · doi:10.1097/hjh.0000000000001004 · Cited by 24 · see citing works
Wang, W.-H., Chen, L., Lee, C., Sun, C., Shyu, Y., Hsu, H.-R., Chien, R.-N., & Wu, I. (2017) · BioMed Research International · doi:10.1155/2017/7435657 · Cited by 23 · see citing works
Parathyroid Gland Function in Primary Aldosteronism
Bekeran, M., Reincke, M., & Asbach, E. (2015) · Hormone and Metabolic Research · doi:10.1055/s-0035-1565224 · Cited by 22 · see citing works
Self-citationLoh, H. H., & Sukor, N. (2019) · Journal of Human Hypertension · doi:10.1038/s41371-019-0294-8 · Cited by 19 · see citing works
Ko, W.-C., Liu, C., Lee, J.-J., Liu, T., Yang, P.-S., Hsu, Y., & Cheng, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115245 · Cited by 17 · see citing works
Adrenocortical incidentalomas and bone: from molecular insights to clinical perspectives
Altieri, B., Muscogiuri, G., Paschou, S. Α., Vryonidou, A., Casa, S. D., Pontecorvi, A., Faßnacht, M., Ronchi, C. L., & Newell-Price, J. D. C. (2018) · Endocrine · doi:10.1007/s12020-018-1696-z · Cited by 16 · see citing works
Postmenopausal osteoporosis is associated with elevated aldosterone/renin ratio
the Chongqing Primary Aldosteronism Study(CONPASS) Group, Shu, X., Mei, M., Ma, L., Wang, Z., Yang, S., Hu, J., Song, Y., He, W., Luo, T., et al. (2018) · Journal of Human Hypertension · doi:10.1038/s41371-018-0069-7 · Cited by 15 · see citing works
Muller, M.-E., Ogna, V. F., Maillard, M. P., Stoudmann, C., Zweiacker, C., Anex, C., Wuerzner, G., Burnier, M., & Bonny, O. (2015) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-015-1714-4 · Cited by 14 · see citing works
Parathyroid hormone may play a role in the pathophysiology of primary hypertension
Oinonen, L., Tikkakoski, A., Koskela, J., Eräranta, A., Kähönen, M. A. P., Niemelä, O. J., Mustonen, J. T., & Pörsti, I. H. (2020) · Endocrine Connections · doi:10.1530/ec-20-0446 · Cited by 12 · see citing works
Bone health among patients with primary aldosteronism: a systematic review and meta-analysis
Loh, H. H., Yee, A. H. A., & Loh, H. S. (2020) · Minerva Endocrinology · doi:10.23736/s0391-1977.18.02867-5 · Cited by 11 · see citing works
Zavatta, G., Dalmazi, G. D., Altieri, P., Pelusi, C., Golfieri, R., Mosconi, C., Balacchi, C., Borghi, C., Cosentino, E. R., Cintio, I. D., et al. (2021) · Endocrine Practice · doi:10.1016/j.eprac.2021.09.002 · Cited by 11 · see citing works
PTH Is a Promising Auxiliary Index for the Clinical Diagnosis of Aldosterone-Producing Adenoma
Zhang, L., Gu, W., Li, Y., Wang, Y., Wang, W., Wang, A., Shen, L., Zang, L., Yang, G., Lü, Z., et al. (2015) · American Journal of Hypertension · doi:10.1093/ajh/hpv146 · Cited by 10 · see citing works
Stanić, B. M., Ilinčić, B., Žeravica, R., Ivanovski, D. M., Čabarkapa, V., & Mijović, R. (2022) · International Journal of Endocrinology · doi:10.1155/2022/3804899 · Cited by 8 · see citing works
Trandafir, A.-I., Gheorghe, A.-M., Sima, O.-C., Ciuche, A., Petrova, E. N., Nistor, C., & Carşote, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417338 · Cited by 6 · see citing works
Saline suppression testing-induced hypocalcemia and implications for clinical interpretations
Parksook, W. W., Brown, J. M., Milks, J., Tsai, L. C., Chan, J., Moore, A., Niebuhr, Y., Honzel, B., Newman, A. J., & Vaidya, A. (2024) · European Journal of Endocrinology · doi:10.1093/ejendo/lvae099 · Cited by 6 · see citing works
Castoldi, G., Carletti, R., Ippolito, S., Villa, I., Palmisano, B., Bolamperti, S., Rubinacci, A., Zerbini, G., Meani, M., Zatti, G., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10112928 · Cited by 6 · see citing works
The Parathyroid Hormone and Peptides Like It. Literature Review
Mokrysheva, N. G., Krupinova, J. A., & Ковалева, Е. В. (2019) · Annals of the Russian academy of medical sciences · doi:10.15690/vramn1104 · Cited by 5 · see citing works
Dobreva, E. A., Евгеньевна, Б. Е., Константиновна, Е. А., Rebrova, O. Y., Nikankina, L. V., Malysheva, N. M., & Mokrysheva, N. G. (2020) · Arterial’naya Gipertenziya (Arterial Hypertension) · doi:10.18705/1607-419x-2019-25-6-630-638 · Cited by 5 · see citing works
Dobreva, E. A., Bibik, E. E., Eremkina, A. K., Ajnetdinova, A. R., Nikankina, L. V., Malysheva, N. M., & Mokrysheva, N. G. (2020) · Terapevticheskii Arkhiv · doi:10.26442/00403660.2020.10.000725 · Cited by 4 · see citing works
“Клинические исследования также иллюстрируют взаимосвязь двух систем у людей без патологии ОЩЖ и надпочечников [20, 21].”
Aldosterone Secretion in Patients With Primary Hyperparathyroidism Without Arterial Hypertension
Castellano, E., Pellegrino, M., Tardivo, V., Attanasio, R., Boriano, A., & Borretta, G. (2021) · Endocrine Practice · doi:10.1016/j.eprac.2021.04.886 · Cited by 4 · see citing works
Song, S., Li, N., Shen, D., Hu, J., Cai, X., Zhu, Q., Zhang, Y., Ma, R., Zhou, P., Zhang, Z., et al. (2025) · Clinical Epidemiology · doi:10.2147/clep.s522455 · Cited by 6 · see citing works
Neue Erkenntnisse zum primären Hyperparathyreoidismus
Siggelkow, H. (2017) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-0043-105588 · Cited by 2 · see citing works
Tang, W., Chai, Y., Jia, H., Wang, B., Liu, T., Wang, H., & Dai, C. (2022) · BMC Endocrine Disorders · doi:10.1186/s12902-022-00955-2 · Cited by 2 · see citing works
Wen, S., Xu, Z., Gong, M., Wang, C., Yuan, Y., Li, Y., Dong, M., Wang, C., Xu, D., Yuan, X., et al. (2025) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s557805 · Cited by 1 · see citing works
Parksook, W. W., Heydarpour, M., Brown, J. M., Turchin, A., Mannstadt, M., & Vaidya, A. (2022) · Clinical Endocrinology · doi:10.1111/cen.14840 · Cited by 1 · see citing works
Relationship Between Parathormone and Obesity-Linked Disorders
Temizkan, Ş., Demir, Ş., Aydın, K., Özderya, A., Öztürk, H. T., & Sargın, M. (2015) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2015.0062
Endocrine Hypertension and Chronic Kidney Disease
Koch, C. A., Pamporaki, C., & Kantorovich, V. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1982-6_16
Calcium-regulating hormonal system in cardiac functional activity
Harutyunyan, K. R., Melkumyan, K., Abrahamyam, H. T., Adamyan, S. H., Khudaverdyan, D. H., & Ter-Markosyan, A. S. (2022) · THE NEW ARMENIAN MEDICAL JOURNAL · doi:10.56936/18290825-2022.16.4-54
阿迪拉克孜, ·. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.13122647
- Authors
- Fischer, E., Hannemann, A., Rettig, R., Lieb, W., Nauck, M., Pallauf, A., Bildingmaier, M., Beuschlein, F., Wallaschofski, H., & Reincke, M.
- Affiliations
- LMU Klinikum (DE)
- Universitätsmedizin Greifswald (DE)
- Universität Greifswald (DE)
- Medizinische Klinik und Poliklinik IV (E.F., A.P., M.B., F.B., M.R.), Klinikum der Ludwig-Maximilians-Universität München, D-80336 München, Deutschland
- Corresponding author
- Hannemann, Anke
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2014-03-01
- Volume
- 99
- Issue
- 3
- Pages
- 965-971
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W1976139404
- Cited by
- 37
- References
- 43
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2022: 5 · 2021: 2 · 2020: 6 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 7 · 2014: 3
- FWCI
- 2.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Javna Agencija za Raziskovalno Dejavnost RS
- Universität Greifswald
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Renin-Angiotensin System Studies
- Health Sciences › Medicine › Nephrology › Parathyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
- Keywords
- aldosterone-renin ratio, parathyroid hormone, renin-angiotensin-aldosterone system, plasma aldosterone, plasma renin concentration, parathyroid hormone regulation, general population, Study of Health in Pomerania
- MeSH terms
- Adult, Aged, Aged, 80 and over, Aldosterone, Female, Germany, Glomerular Filtration Rate, Humans, Male, Middle Aged, Parathyroid Hormone, Renin, Renin-Angiotensin System, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
