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Cited by 216Adrenal Hormones and DisordersHormonal Regulation and HypertensionStress Responses and Cortisol

The DOI matches its Crossref record.

ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin.

Slominski, A, Ermak, G, Mihm, M·1996·The Journal of Clinical Endocrinology & Metabolism
DOI 10.1210/jcem.81.7.8675607
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Abstract

Evidence is provided that mRNA for ACTH (MC-2) receptor and mRNAs for three obligatory enzymes of steroid synthesis including cytochromes P450scc, P450c17 and P450c21 are expressed in normal and pathologic human skin. Thus, molecular elements of the distal loop of the "pituitary-adrenal axis" such as the MC-2, CYP11A1, CYP17 and CYP21A2 genes are expressed in the skin.

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Metadata

Authors
Slominski, A., Ermak, G., & Mihm, M.
Affiliations
Albany Medical College (US)
ORCID
Venue
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Published
1996-07
Volume
81
Issue
7
Pages
2746-2749
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
DOI
10.1210/jcem.81.7.8675607
OpenAlex
W2029377942
Cited by
216
References
0
Citations by year
2025: 2 · 2024: 4 · 2023: 3 · 2022: 3 · 2021: 5 · 2020: 6 · 2019: 5 · 2018: 4 · 2017: 8 · 2016: 6 · 2015: 8 · 2014: 12 · 2013: 13 · 2012: 9
FWCI
8.06
Type
journal article
Language
en
Open access
closed
Locations
  • The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords
ACTH receptor, CYP11A1, CYP17, CYP21A2, skin, steroidogenesis, cytochrome P450scc, P450c17, mRNA expression, pituitary-adrenal axis
MeSH terms
Base Sequence, Cholesterol Side-Chain Cleavage Enzyme, Humans, Molecular Sequence Data, RNA-Directed DNA Polymerase, RNA, Messenger, Skin, Steroid 17-alpha-Hydroxylase, Steroid 21-Hydroxylase, Gene Expression, Polymerase Chain Reaction, Receptors, Corticotropin

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CoChat. (2026). Citation check: ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin. https://app.cochat.ai/papers/10.1210/jcem.81.7.8675607
The paper
Slominski, A., Ermak, G., & Mihm, M. (1996). ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem.81.7.8675607