The DOI matches its OpenAlex record; 19 of the 19 references it cites were found in a registry or an index.
Serum Inhibin B as a Marker of Spermatogenesis
Open accessAbstract
Inhibin B is produced by Sertoli cells, provides negative feedback on FSH secretion, and may prove to be an important marker for the functioning of seminiferous tubules. The purpose of the present study was to examine the relationship between the spermatogenic function of the testis of subfertile men and the plasma concentrations of inhibin B and FSH. These parameters were estimated in a group of 218 subfertile men. Serum inhibin B levels were closely correlated with the serum FSH levels (r = -0.78, P < 0.001), confirming the role of inhibin B as feedback signal for FSH production. The spermatogenic function of the testis was evaluated by determining testicular volume and total sperm count. Inhibin B levels were significantly correlated with the total sperm count and testicular volume (r = 0.54 and r = 0.63, respectively; P < 0.001). Testicular biopsies were obtained in 22 of these men. Inhibin B was significantly correlated with the biopsy score (r = 0.76, P < 0.001). Receiver operating characteristic analysis revealed a diagnostic accuracy of 95% for differentiating competent from impaired spermatogenesis for inhibin B, whereas for FSH, a value of 80% was found. We conclude that inhibin B is the best available endocrine marker of spermatogenesis in subfertile men.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
DeLong, E. R., DeLong, D. M., & Clarke-Pearson, D. L. (1988) · Biometrics · doi:10.2307/2531595 · Cited by 22,649
The meaning and use of the area under a receiver operating characteristic (ROC) curve.
Hanley, J. A., & McNeil, B. J. (1982) · Radiology · doi:10.1148/radiology.143.1.7063747 · Cited by 21,856
Johnsen, S. G. (1970) · Hormone Research in Paediatrics · doi:10.1159/000178170 · Cited by 1,714
WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Male
Rowe, P. M., Comhaire, F. H., Hargreave, T. B., & Mellows, H. J. (2000) · Cited by 434
Anawalt, B. D. (1996) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.81.9.3341 · Cited by 413
Inhibin-B: a likely candidate for the physiologically important form of inhibin in men
Illingworth, P. J. (1996) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.81.4.1321 · Cited by 331
Jensen, T. K., Andersson, A.-M., Hjollund, N. H. I., Scheike, T., Kolstad, H., Giwercman, A., Henriksen, T. B., Ernst, E., Bonde, J. P., Olsen, J., et al. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.12.4456 · Cited by 303
Andersson, A.-M., Juul, A., Petersen, J. H., Müller, J., Groome, N. P., & Skakkebæk, N. E. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.12.4449 · Cited by 258
Isolation of Inhibin α-Subunit Precursor Proteins from Bovine Follicular Fluid*
ROBERTSON, D. M., GIACOMETTI, M., FOULDS, L. M., LAHNSTEIN, J., GOSS, N. H., HEARN, M. T. W., & KRETSER, D. M. D. (1989) · Endocrinology · doi:10.1210/endo-125-4-2141 · Cited by 219
Serum FSH and testicular morphology in male infertility
Bergmann, M., Behre, H. M., & Nieschlag, E. (1994) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1994.tb02455.x · Cited by 186
Cited by
Welt, C., Sidis, Y., Keutmann, H., & Schneyer, A. (2002) · Experimental Biology and Medicine · doi:10.1177/153537020222700905 · Cited by 324
Sikaris, K., McLachlan, R. I., Kazlauskas, R., de Kretser, D., Holden, C. A., & Handelsman, D. J. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0962 · Cited by 259
Ravnborg, T. L., Jensen, T. K., Andersson, A.-M., Toppari, J., Skakkebaek, N. E., & Jorgensen, N. (2011) · Human Reproduction · doi:10.1093/humrep/der011 · Cited by 96
Testicular Sertoli cell function in male systemic lupus erythematosus
Suehiro, R. M., Borba, E. F., Bonfa, E., Okay, T. S., Cocuzza, M., Soares, P. M. F., & Silva, C. A. A. (2008) · Rheumatology · doi:10.1093/rheumatology/ken338 · Cited by 76
Metadata
- Authors
- Pierik, F. H., Vreeburg, J. T. M., Stijnen, T., de Jong, F. H., & Weber, R. F. A.
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- Oxford University Press
- Published
- 1998-09-01
- Volume
- 83
- Issue
- 9
- Pages
- 3110-3114
- ISSN
- 0021-972X (ISSN-L)
- OpenAlex
- W2109974307
- Cited by
- 353
- References
- 19
- FWCI
- 16.74
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Serum Inhibin B as a Marker of Spermatogenesis. https://app.cochat.ai/papers/10.1210/jc.83.9.3110
- The paper
- Pierik, F. H., Vreeburg, J. T. M., Stijnen, T., de Jong, F. H., & Weber, R. F. A. (1998). Serum Inhibin B as a Marker of Spermatogenesis. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jc.83.9.3110
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
