Effects of Cortisol and Growth Hormone on Lipolysis in Human Adipose Tissue
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Insulin and adrenaline are critical confounders in the effects of glucocorticoids on lipolysis.
“Over and above prevailing glucocorticoid concentrations, a further critical confounder is the effect of other hormones regulating lipolysis, notably insulin and adrenaline.5, 6”
From Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct (2017) · cites this paper as [6]
In vitro studies in adipocytes have shown lipolytic rates to be increased, unchanged or decreased by glucocorticoids.
“For example, in vitro studies in adipocytes have shown lipolytic rates to be increased,4 unchanged5 or decreased6 by glucocorticoids.”
From Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct (2017) · cites this paper as [6]
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“Over and above prevailing glucocorticoid concentrations, a further critical confounder is the effect of other hormones regulating lipolysis, notably insulin and adrenaline.(5,6) In vivo, the effect of interactions between cortisol and either adrenaline(11) or insulin(12) has been examined only once in humans, although…”
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- Authors
- Ottosson, M.
- Corresponding author
- Ottosson, M.
- Venue
- Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2000-02-01
- Volume
- 85
- Issue
- 2
- Pages
- 799-803
- ISSN
- 0021-972X (ISSN-L)
- OpenAlex
- W4234202500
- Cited by
- 64
- References
- 0
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 1 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 1 · 2014: 1 · 2013: 7 · 2012: 3
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
- Keywords
- cortisol, growth hormone, lipolysis, human adipose tissue, adipocytes, lipolysis regulation
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