Fat Accumulation in the Liver Is Associated with Defects in Insulin Suppression of Glucose Production and Serum Free Fatty Acids Independent of Obesity in Normal Men

Seppala-Lindroos, A.·2002·Journal of Clinical Endocrinology & Metabolism

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  13. Molecular Basis of Liver Disease
    Satdarshan P. Monga, Jaideep Behari · 2009 · Elsevier eBooks
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  15. Brain, Environment, Hormone-Based Appetite, Ingestive Behavior, and Body Weight
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  16. Variabilité de la triglycéridémie : impact métabolique. De la dysfonction du tissu adipeux à l’adiposité viscérale et à la stéatopathie métabolique, les chemins de l’insulino-résistance
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  17. Association between Cardiorespiratory Fitness, Muscle Strength, and Non-Alcoholic Fatty Liver Disease in Middle-Aged Men
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  18. Studies of the interaction between diabetes family history, exercise, adiposity and metabolic health
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  19. Integração entre vias metabolicas e inflamatorias durante a esteatose hepatica induzida por dieta hiperlipidica
    Dennys E. Cintra · 2008
  20. The Effect of Fenofibrate and Exercise on Metabolic Syndrome and Hepatic Steatosis in OLETF Rats
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  21. Association of Hepatitis C Virus Infection and Diabetes Mellitus
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  22. Does glucocorticoid dysregulation contribute to the link between cigarette smoking and insulin resistance?
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  23. Antidiabetic activity of Vaccinium vitis-idaea, a medicinal plant from the traditional pharmacopeia of the James Bay Cree
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  24. The reversibility of type 2 diabetes
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  25. [Medical-historical survey on epilepsy and older concepts about the therapy of epilepsy].
    E Vencovský · 1972 · PubMed
  26. Genomic studies in non-alcoholic fatty liver disease
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  27. Reducing VEGFB accelerates NAFLD and insulin resistance in mice via inhibiting AMPK signaling pathway
    Rongrong Li, Yuqi Li, Xueling Yang, Yaorui Hu, Haining Yu, Yana Li · 2022 · Research Square
  28. The effects of different types of dietary fats in the liver
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  29. Berry polyphenol absorption and the effect of northern berries on metabolism, ectopic fat accumulation, and associated diseases
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  30. The Liver and Insulin Resistance: The Important Convergence of Endocrinology and Hepatology
    Charissa Chang, Kerry N. Whitt, Zhenqi Liu, Stephen Hugh Caldwell · 2009 · Humana Press eBooks
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  32. Exercise, Adiposity, and Regional Fat Distribution
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    Taku Watanabe, Tomonori Takeuchi, Naoto Kubota, Tasuku Wainai, Keisuke Kataoka, Toshitaka Nakaya, Ayako Sugimoto, Takahiro Sato, Hiroshi Ohira, Ichizo Tsujino et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
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    Patrícia Jacob · 2012
  59. The role of free fatty acids in ectopic lipid accumulation, insulin resistance and inflammation in humans.
    Noud A. van Herpen · 2012
  60. Interplay between hormones, nutrients and adipose depots in the regulation of insulin sensitivity : an experimental study in rat and human adipocytes
    Magdalena Lundgren · 2006 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
  61. Aspects involved in the (patho)physiology of the metabolic syndrome
    Ilse Duivenvoorden · 2006 · Leiden Repository (Leiden University)
  62. Adipose tissue inflammation, liver fat and insulin resistance in humans
    Janne Makkonen · 2010 · Työväentutkimus Vuosikirja
  63. Fatty acid metabolism, impaired glucose tolerance and the effects of lifestyle
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  64. Recherche de déterminants génétiques des phénotypes associés au syndrome métabolique en population
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  67. Spectroscopy of tissue triglyceride composition : In vitro and in vivo studies
    Jesper Lundbom · 2010 · Työväentutkimus Vuosikirja
  68. Modulation of VLDL triglyceride metabolism
    Silvia Bijland · 2010 · Leiden Repository (Leiden University)
  69. Aspects on gender, quality of life and diastolic function in patients with cardiovascular disease and type 2 diabetes
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  70. Insulin therapy in type 2 diabetes : Initiation, impact on liver fat, role of combination therapy with glitazones or glindes
    Leena Juurinen · 2014 · Työväentutkimus Vuosikirja
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  75. LIVER FAT IN THE METABOLIC SYNDROME AND TYPE 2 DIABETES
    Anna Kotronen · 2008 · Työväentutkimus Vuosikirja
  76. Adipose tissue inflammation, hepatic fat accumulation and insulin resistance
    Maria Kolak · 2008 · Figshare
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  80. Perinatal essential fatty acid deficiency in mice - effects on metabolism and behaviour
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  81. Effects of Eight Weeks of High-intensity Interval Training on Blood Glucose Control, Endothelial Function, and Visceral Fat in Obese Adults
    Brandon J. Sawyer · 2013
  82. Relationship of centrally-located body fat to appetitive hormones in healthy postmenopausal women
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  83. Genetic Association of the Tenomodulin Gene (TNMD) with
    Anna‐Maija Tolppanen · 2009
  84. Pathogenesis and treatment of lipodystrophy in hiv-infected patients receiving highly active antiretroviral therapy
    Jussi Sutinen · 2003 · Työväentutkimus Vuosikirja
  85. Investigation of the relationship between genetic and environmental risk factors associated with obesity and insulin resistance in South African patients with non-alcoholic fatty liver disease (NAFLD)
    Jakobus Pretorius · 2012 · SUNScholar (Stellenbosch University)
  86. Insulin; Sense and Sensitivity
    Wiebe Boorsma · 2008 · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam)
  87. Einfluss der Histon Deacetylase 6 auf den Glucocorticoid Rezeptor-vermittelten Glucosestoffwechsel
    Robin Winkler · 2012 · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver
  88. Estudio del factor de transcripción SREBP1 en estados de resistencia a insulina.
    Santiago Vernia Miralles · 2007 · DIGITAL.CSIC (Spanish National Research Council (CSIC))
  89. Análisis en animales transgénicos del papel del incremento en la gliceroneogénesis o en la captación de glucosa por el tejido adiposo
    Muñoz Forero, Sergio Antonio · 2006 · TDX (Tesis Doctorals en Xarxa)
  90. Insulin receptor and IGF-I receptor Bioactivity in Health and Disease
    Aimee J. Varewijck · 2013 · EUR Research Repository (Erasmus University Rotterdam)
  91. with overfeeding in healthy young men combined composition during 14 days of step reduction Changes in insulin sensitivity precede changes in body
    Bente Klarlund Pedersen, Rikke Krogh‐Madsen, Carsten Eckhart Thomsen, Sine Haugaard Knudsen, Louise Seier Hansen, Maria Pedersen, Matthew James Laye, John P. Kirwan, Thomas P. J. Solomon, Steven K. Malin et al. · 2015
  92. Etiology and reversibility
    Roy Taylor · 2013
  93. Effect of Exercise on the Distribution of Triglycerides among Various Tissues of Swiss Albino Mice
    Silvia Sultana, Naila Binte Iqbal · 2013
  94. Retinoic acid in adipocyte biology
    Daniel C. Berry · 2011 · OhioLink ETD Center (Ohio Library and Information Network)
  95. Liver markers, prevalence of the metabolic syndrome abnormalities and effect of Roux-en-Y gastric bypass in morbidly obese subjects
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  96. Effects of Exercise Training on Metabolic Intermediate Phenotypes in Inbred Rat Strains
    Sumona Ghosh · 2007 · OhioLink ETD Center (Ohio Library and Information Network)
  97. Nutritional regulation of central fat mass and obesity-associated (FTO) expression, and its association with the central melanocortin signaling in the regulation of energy homeostasis
    Nicole J. Poritsanos · 2010 · Mspace (University of Manitoba)
  98. Impacto da ovariectomia sobre alterações metabólicas e inflamatórias em modelos de obesidade induzida por dieta em ratas
    Anna Carolina Saúde Dantas · 2013 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
  99. Does she have a fatty liver?
    Ken A. Sikaris, Prithi S. Bhathal · 2003 · PubMed
  100. The Effect of Ginseng (The Genus Panax) on Glycemic and Vascular Health
    A H A M Esra' Shishtar · 2014 · TSpace (University of Toronto)