Fat Accumulation in the Liver Is Associated with Defects in Insulin Suppression of Glucose Production and Serum Free Fatty Acids Independent of Obesity in Normal Men

Beta cell functionality and hepatic insulin resistance are major contributors to type 2 diabetes remission and starting pharmacological therapy: from CORDIOPREV randomized controlled trial

Roncero‐Ramos, I., Gutierrez-Mariscal, F. M., Gómez-Delgado, F., Villasanta‐Gonzalez, A., Torres-Peña, J. D., de la Cruz, S., Rangel-Zúñiga, O. A., Luque, R. M., Ordovás, J. M., Delgado‐Lista, J., et al. (2021) · Translational research · doi:10.1016/j.trsl.2021.07.001 · Cited by 24

Comparison of Alanine Aminotransferase, White Blood Cell Count, and Uric Acid in Their Association with Metabolic Syndrome: A Study of Korean Adults

Kang, Y. H., Min, H., Kim, I. J., Kim, Y. K., & Son, S. M. (2008) · Endocrine Journal · doi:10.1507/endocrj.k08e-077 · Cited by 24

Effects of Teucrium polium Ethyl acetate Extract on Serum, Liver and Muscle Triglyceride Content of Sucrose-Induced Insulin Resistance in Rat.

Mousavi, S. E., Shahriari, A., Ahangarpour, A., Vatanpour, H., & Jolodar, A. (2012) · Europe PMC (PubMed Central) · Cited by 24

Hepatic fat is not associated with β-cell function or postprandial free fatty acid response

Rijkelijkhuizen, J. M., Doesburg, T., Girman, C. J., Mari, A., Rhodes, T., Gastaldelli, A., Nijpels, G., & Dekker, J. M. (2009) · Metabolism · doi:10.1016/j.metabol.2008.09.013 · Cited by 24

Effects of short-term sprint interval and moderate-intensity continuous training on liver fat content, lipoprotein profile, and substrate uptake: a randomized trial

Motiani, K. K., Savolainen, A., Toivanen, J., Eskelinen, J., Yli-Karjanmaa, M., Virtanen, K. A., Saunavaara, V., Heiskanen, M. A., Parkkola, R., Haaparanta‐Solin, M., et al. (2019) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00900.2018 · Cited by 28

Insulin sensitivity and hepatic steatosis in obese subjects with normal glucose tolerance

Venturi, C., Zoppini, G., Zamboni, C., & Muggeo, M. (2004) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/s0939-4753(04)80005-x · Cited by 24

Heme oxygenase-1 gene promoter polymorphism and the risk of pediatric nonalcoholic fatty liver disease

Chang, P.-F., Lin, Y.-C., Liu, K., Yeh, S.-J., & Ni, Y. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.46 · Cited by 24

Waist circumference and BMI cut-off points to predict risk factors for metabolic syndrome among outpatients in a district hospital.

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Insulin therapy in type 2 diabetes: role of the long‐acting insulin glargine analogue

Yki-Järvinen, H. (2004) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2004.01356.x · Cited by 25

Calorie restriction and reversal of type 2 diabetes

Taylor, R. (2016) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2016.1239525 · Cited by 24

Pathophysiological Mechanisms and Clinical Associations of Non-Alcoholic Fatty Pancreas Disease

Pagkali, A., Makris, A. P., Brofidi, K., Agouridis, A. P., & Filippatos, T. D. (2024) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s397643 · Cited by 23

Clinical association between serum γ‐glutamyltransferase levels and the development of insulin resistance in Korean men: a 5‐year follow‐up study

Ryoo, J., Oh, C., Kim, H. S., Park, S. K., & Choi, J. (2013) · Diabetic Medicine · doi:10.1111/dme.12315 · Cited by 23

High free fatty acid levels are associated with stroke recurrence and poor functional outcome in Chinese patients with ischemic stroke

Niu, Z., Hu, H., & Tang, F. (2016) · The journal of nutrition health & aging · doi:10.1007/s12603-016-0852-5 · Cited by 23

Liver Fetuin-A at Initiation of Insulin Resistance

Lanthier, N., Lebrun, V., Molendi‐Coste, O., van Rooijen, N., & Leclercq, I. A. (2022) · Metabolites · doi:10.3390/metabo12111023 · Cited by 23

No need for a large belly to have NASH

Machado, M. V., & Cortez‐Pinto, H. (2011) · Journal of Hepatology · doi:10.1016/j.jhep.2011.01.010 · Cited by 23

γ‐Glutamyltransferase, Obesity, Physical Activity, and the Metabolic Syndrome in Indigenous Australian Adults

Li, M., Campbell, S., & McDermott, R. A. (2009) · Obesity · doi:10.1038/oby.2008.617 · Cited by 23

Subclinical inflammation in relation to insulin resistance in prediabetic subjects with nonalcoholic fatty liver disease

Hossain, I. A., Akter, S., Bhuiyan, F. R., Shah, M. R., Rahman, M. K., & Ali, L. (2016) · BMC Research Notes · doi:10.1186/s13104-016-2071-x · Cited by 24

Chronic saponin treatment attenuates damage to the pancreas in chronic alcohol-treated diabetic rats

Choi, M., Kwak, S. M., Bang, S. H., Jeong, J.-E., & Kim, D. (2016) · Journal of Ginseng Research · doi:10.1016/j.jgr.2016.09.002 · Cited by 23

Molecular imaging of diabetes and diabetic complications: Beyond pancreatic β-cell targeting

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Pancreatic Fat is not significantly correlated with β-cell Dysfunction in Patients with new-onset Type 2 Diabetes Mellitus using quantitative Computed Tomography

Li, Y., Sang, Y., Sun, Y., Liu, X., Geng, H., Zha, M., Wang, B., Teng, F., Sun, H., Wang, Y., et al. (2020) · International Journal of Medical Sciences · doi:10.7150/ijms.46395 · Cited by 23

Non-alcoholic fatty liver disease in diabetes: When to refer to the hepatologist?

Khandelwal, R., Dassanayake, A. S., Conjeevaram, H. S., & Singh, S. P. (2021) · World Journal of Diabetes · doi:10.4239/wjd.v12.i9.1479 · Cited by 25

Therapeutic potential of antisense oligonucleotides for the management of dyslipidemia

Carpentier, A. C., Labbé, S. M., Grenier–Larouche, T., & Noll, C. (2011) · Clinical Lipidology · doi:10.2217/clp.11.60 · Cited by 23

PNPLA 3I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection

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Combination of Pancreastatin inhibitor PSTi8 with metformin inhibits Fetuin-A in type 2 diabetic mice

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Adipocyte size is associated with NAFLD independent of obesity, fat distribution, and PNPLA3 genotype

Petäjä, E. M., Sevastianova, K., Hakkarainen, A., Orho‐Melander, M., Lundbom, N. M. I., & Yki‐Järvinen, H. (2013) · Obesity · doi:10.1002/oby.20114 · Cited by 22

Independent association of liver fat accumulation with insulin resistance

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Dietary Phospholipids Ameliorate Fructose-Induced Hepatic Lipid and Metabolic Abnormalities in Rats

Mori, T., Kondo, H., Hase, T., & Murase, T. (2011) · Journal of Nutrition · doi:10.3945/jn.111.143602 · Cited by 22

Increased hepatic fatty acid polyunsaturation precedes ectopic lipid deposition in the liver in adaptation to high-fat diets in mice

Soares, A. F., Duarte, J. M. N., & Rolf Gruetter, A. (2017) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-017-0654-8 · Cited by 22

Adipose tissue insulin resistance in adolescents with and without type 2 diabetes

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Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats

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Non-alcoholic fatty liver disease presence and severity are associated with aortic stiffness beyond abdominal obesity: The ELSA-Brasil

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Lycium ruthenicum Murr. alleviates nonalcoholic fatty liver in mice

Lu, K., Wang, J., Yu, Y., Wu, Y., & He, Z. (2020) · Food Science & Nutrition · doi:10.1002/fsn3.1445 · Cited by 21

A comparison of NAFLD and MAFLD diagnostic criteria in contemporary urban healthy adults in China: a cross-sectional study

Liu, Q., Zhao, G., Li, Q., Wu, W., Zhang, Y., & Bian, H. (2022) · BMC Gastroenterology · doi:10.1186/s12876-022-02576-4 · Cited by 21

Prediction of total and visceral fat contents using anthropometric measures of adiposity in women

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Metabolic Syndrome in the Pediatric Population: A Short Overview

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The herbal extract ALS-L1023 from Melissa officinalis reduces weight gain, elevated glucose levels and β-cell loss in Otsuka Long-Evans Tokushima fatty rats

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Impact of body weight, diet and lifestyle on nonalcoholic fatty liver disease

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What is the reason of elevated alanine aminotransferase level in HBeAg negative patients with low viremia: NAFLD or chronic hepatitis?

Demır, K., Akyüz, F., Özdil, S., Aksoy, N., Kaymakoğlu, S., Poturoğlu, Ş., Akyüz, Ü., Besisik, F. S., Boztaş, G., Mungan, Z. A., et al. (2007) · Annals of Hepatology · doi:10.1016/s1665-2681(19)31938-6 · Cited by 21

Identification of nonalcoholic fatty liver disease following pancreatectomy for noninvasive intraductal papillary mucinous neoplasm

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Liver Transcriptomic Reveals Novel Pathways of Empagliflozin Associated With Type 2 Diabetic Rats

Lv, Q., Le, L., Xiang, J., Jiang, B., Chen, S., & Xiao, P. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00111 · Cited by 20

Association of serum methionine metabolites with non-alcoholic fatty liver disease: a cross-sectional study

Tang, Y., Chen, X., Chen, Q., Xiao, J., Mi, J., Liu, Q., You, Y., Chen, Y., & Ling, W. (2022) · Nutrition & Metabolism · doi:10.1186/s12986-022-00647-7 · Cited by 20

Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet

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Lipid-Induced Insulin Resistance in the Liver

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Liver TAG Transiently Decreases While PL n‐3 and n‐6 Fatty Acids are Persistently Elevated in Insulin Resistant Mice

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Transgenic expression of mutant peroxisome proliferator–activated receptor γ in liver precipitates fasting–induced steatosis but protects against high-fat diet–induced steatosis in mice

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JTT‐130, a novel intestine‐specific inhibitor of microsomal triglyceride transfer protein, suppresses high fat diet‐induced obesity and glucose intolerance in Sprague‐Dawley rats

Hata, T., Mera, Y., Tadaki, H., Kuroki, Y., Kawai, T., Ohta, T., & Kakutani, M. (2011) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2011.01368.x · Cited by 19

Liver of ovariectomized rats is resistant to resorption of lipids

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Ectopic adiposity and cardiometabolic health in COPD

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Association between homocysteine and nonalcoholic fatty liver disease: Mendelian randomisation study

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Phenotypical heterogeneity linked to adipose tissue dysfunction in patients with Type 2 diabetes

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Fructose threshold for inducing organ damage in a rat model of nonalcoholic fatty liver disease

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Impact of Different Fat Depots on Insulin Sensitivity: Predominant Role of Liver Fat

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Lack of association of CPT1A polymorphisms or haplotypes on hepatic lipid content or insulin resistance in Japanese individuals with type 2 diabetes mellitus

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Inverse correlation between serum adiponectin concentration and hepatic lipid content in Japanese with type 2 diabetes

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Yishen Huashi granule modulated lipid metabolism in diabetic nephropathy via PI3K/AKT/mTOR signaling pathways

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Polyploidy and mTOR signaling: a possible molecular link

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Causal Relationship of Non-alcoholic Fatty Liver Disease with Obesity and Insulin Resistance

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Disassociation of Liver and Muscle Insulin Resistance from Ectopic Lipid Accumulation in Low-Birth-Weight Individuals

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Quantum coherence spectroscopy to measure dietary fat retention in the liver

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Beneficial effects of omega-3 fatty acids on the consequences of a fructose diet are not mediated by PPAR delta or PGC1 alpha

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Ethnicity-specific alterations of plasma and hepatic lipidomic profiles are related to high NAFLD rate and severity in Hispanic Americans, a pilot study

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Impaired peripheral insulin sensitivity in non‐obese Japanese patients with type 2 diabetes mellitus and fatty liver

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Fatty liver index predicts incident diabetes in a Japanese general population with and without impaired fasting glucose

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Non-alcoholic fatty liver disease and type 2 diabetes mellitus: the problem of conjunction and phasing

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The C-681G Polymorphism of the PPAR-γ Gene Is Associated with Susceptibility to Non-Alcoholic Fatty Liver Disease

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Association of the −112A > C polymorphism of the uncoupling protein 1 gene with insulin resistance in Japanese individuals with type 2 diabetes

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Insulin resistance and beta cell function before and after sleeve gastrectomy in obese patients with impaired fasting glucose or type 2 diabetes

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A High-Fructose-High-Coconut Oil Diet Induces Dysregulating Expressions of Hippocampal Leptin and Stearoyl-CoA Desaturase, and Spatial Memory Deficits in Rats

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A Controlled Fermented Samjunghwan Herbal Formula Ameliorates Non-alcoholic Hepatosteatosis in HepG2 Cells and OLETF Rats

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A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation

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Intrahepatic lipid content is linked to insulin resistance in obese subjects

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Early detection of liver steatosis by magnetic resonance imaging in rats infused with glucose and Intralipid solutions and correlation to insulin levels

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Analysis of Biochemical Markers Related to Fatty Liver Patients

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Insulin Resistance: Causes and Consequences

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Liver fat is not a marker of metabolic risk in lean premenopausal women

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White adipose tissue in metabolic associated fatty liver disease

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Relationships between fat deposition in the liver and skeletal muscle and insulin sensitivity in Japanese individuals: a pilot study

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Lipolytic and esterolytic activity‐based profiling of murine liver

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CIRCULATING IGFBP-2 LEVELS ARE INCREMENTALLY LINKED TO CORRELATES OF THE METABOLIC SYNDROME AND INDEPENDENTLY ASSOCIATED WITH VLDL TRIGLYCERIDES

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Additive effect of non-alcoholic fatty liver disease on the development of diabetes in individuals with metabolic syndrome

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Insulin clearance as the major player in the hyperinsulinaemia of black African men without diabetes

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Generation and characterization of a mouse model of the metabolic syndrome: apolipoprotein E and aromatase double knockout mice

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