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Experience with a Quantitative Test for Normal or Decreased Amounts of Follicle Stimulating Hormone in the Urine in Endocrinological Diagnosis
Abstract
SINCE 1930 when Zondek (1) first described a method for the assay of follicle stimulating hormone (Prolan A, thylakentrin, pituitary gonadotropin A) in the urine, various modifications of this test have been in use in the Biological Laboratory of the Massachusetts General Hospital. The test has been invaluable, not only in the sorting out of the various causes for hypoestrinism (2), but also in the elucidation of various syndromes in males (3) as well as in females (4). Furthermore, the importance of the test is accentuated by the fact that follicle stimulating hormone is the only pituitary hormone at present that can be easily assayed. It is felt, moreover, that the failure of this test to gain widespread use in medical clinics is due to faulty methods. In a previous communication (2) it was pointed out that hypoestrinism could be the result of primary ovarian failure or of ovarian hypof unction secondary to underproduction of follicle stimulating hormone.
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Citations
Cited by
Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline
Gordon, C. M., Ackerman, K. E., Berga, S. L., Kaplan, J. R., Mastorakos, G., Misra, M., Murad, M. H., Santoro, N. F., & Warren, M. P. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-00131 · Cited by 600
Powell, G. F., Brasel, J. A., Raiti, S., & Blizzard, R. M. (1967) · New England Journal of Medicine · doi:10.1056/nejm196706082762302 · Cited by 317
THE METABOLIC EFFECTS OF STEROID HORMONES IN OSTEOPOROSIS
Reifenstein, E. C., & Albright, F. (1947) · Journal of Clinical Investigation · doi:10.1172/jci101787 · Cited by 217
Self-citationFamilial Isolated Thyrotropin Deficiency with Cretinism
Miyai, K., Azukizawa, M., & Kumahara, Y. (1971) · New England Journal of Medicine · doi:10.1056/nejm197111042851902 · Cited by 113
Segaloff (1951) · doi:10.1002/1097-0142(195103)4:2
Metadata
- Authors
- Klinefelter, H. F., Albright, F., & Griswold, G. C.
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 1943-10
- Volume
- 3
- Issue
- 10
- Pages
- 529-544
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2074488082
- Cited by
- 392
- References
- 0
- FWCI
- 11.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Experience with a Quantitative Test for Normal or Decreased Amounts of Follicle Stimulating Hormone in the Urine in Endocrinological Diagnosis. https://app.cochat.ai/papers/10.1210/jcem-3-10-529
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- Klinefelter, H. F., Albright, F., & Griswold, G. C. (1943). Experience with a Quantitative Test for Normal or Decreased Amounts of Follicle Stimulating Hormone in the Urine in Endocrinological Diagnosis. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-3-10-529
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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