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Cited by 346

The DOI matches its Crossref record.

A Simplified Method for the Quantitative Determination of Testosterone-Estradiol-Binding Globulin Activity in Human Plasma

ROSNER, WILLIAM·1972·The Journal of Clinical Endocrinology & Metabolism
DOI 10.1210/jcem-34-6-983
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Abstract

A rapid and simple method for the measurement of testosterone-estradiol-binding globulin in human plasma is described. The bind- ing protein is saturated with dihydrotestosterone (DHT), precipitated with 50% ammonium sul- fate, and the mass of bound DHT determined from the known specific activity of the added steroid. Normal values, expressed as M-g DHT bound/100 ml serum are: men, 0.93 ±. 0.06 (SEM); women, 1.85 ± 0.13; pregnancy, 12.4 ± 0.67. Elevated values were observed in men with cirrhosis of the liver and patients with thyrotoxi- cosis. Normal values were observed in abstinent alcoholics and in pregnant subjects with diabetes or hypertension. (/ Clin Endocrinol Metab 34: 983, 1972)

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Metadata

Authors
ROSNER, W.
Venue
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Published
1972-06
Volume
34
Issue
6
Pages
983-988
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
DOI
10.1210/jcem-34-6-983
OpenAlex
W2071666615
Cited by
346
References
0
FWCI
10.10
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Simplified Method for the Quantitative Determination of Testosterone-Estradiol-Binding Globulin Activity in Human Plasma. https://app.cochat.ai/papers/10.1210/jcem-34-6-983
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ROSNER, W. (1972). A Simplified Method for the Quantitative Determination of Testosterone-Estradiol-Binding Globulin Activity in Human Plasma. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-34-6-983

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