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Cited by 272

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Increase of Serum Growth Hormone Concentration following Thyrotropin-Releasing Hormone Injection in Patients with Acromegaly or Gigantism

IRIE, MINORU, TSUSHIMA, TOSHIO·1972·The Journal of Clinical Endocrinology & Metabolism
DOI 10.1210/jcem-35-1-97
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Abstract

Effect of TRH administration on serum TSH and GH was studied in 9 normal subjects and 11 patients with acromegaly or gigantism. TRH provoked a prompt increase of serum TSH in normal subjects, whereas no appreciable change of serum GH was observed. Serum TSH responses to TRH were lower in most of the patients, but 8 out of the patients showed a remarkable increase of serum GH within 30 min after TRH injection. These results appear to indicate that specificity of TRH is not absolute in the functioning pituitary tumor secreting GH.

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Metadata

Authors
IRIE, M., & TSUSHIMA, T.
Venue
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Published
1972-07
Volume
35
Issue
1
Pages
97-100
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
DOI
10.1210/jcem-35-1-97
OpenAlex
W2066922718
Cited by
272
References
0
FWCI
8.08
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Increase of Serum Growth Hormone Concentration following Thyrotropin-Releasing Hormone Injection in Patients with Acromegaly or Gigantism. https://app.cochat.ai/papers/10.1210/jcem-35-1-97
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IRIE, M., & TSUSHIMA, T. (1972). Increase of Serum Growth Hormone Concentration following Thyrotropin-Releasing Hormone Injection in Patients with Acromegaly or Gigantism. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-35-1-97

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.