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Cited by 340

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SPECIFIC NUCLEAR TRIIODOTHYRONINE BINDING SITES IN RAT LIVER AND KIDNEY1

OPPENHEIMER, J.H., KOERNER, D., SCHWARTZ, H.L., SURKS, M.I.·1972·The Journal of Clinical Endocrinology & Metabolism

Abstract

Injection of increasing quantities of L-triiodothyronine (T3) resulted in a progressive decrease in the proportion of T3 bound to the nuclear fraction of rat liver and kidney cells. A similar dose-response relationship could not be demonstrated for other ultracentrifugal fractions. Only a modest reduction in nuclear binding of thyroxine was observed after injection of large amounts of this iodothyronine. The results indicate the presence of relatively specific binding sites for T3 in the nuclei of rat liver and kidney.

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Metadata

Authors
OPPENHEIMER, J. H., KOERNER, D., SCHWARTZ, H. L., & SURKS, M. I.
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
1972-08
Volume
35
Issue
2
Pages
330-333
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W1986006697
Cited by
340
References
0
FWCI
20.20
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: SPECIFIC NUCLEAR TRIIODOTHYRONINE BINDING SITES IN RAT LIVER AND KIDNEY1. https://app.cochat.ai/papers/10.1210/jcem-35-2-330
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OPPENHEIMER, J. H., KOERNER, D., SCHWARTZ, H. L., & SURKS, M. I. (1972). SPECIFIC NUCLEAR TRIIODOTHYRONINE BINDING SITES IN RAT LIVER AND KIDNEY1. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-35-2-330

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.