The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Thyroid Hormone Action at the Cellular Level
Abstract
A large body of circumstantial evidence suggests that the basic unit of thyroid hormone action is the triiodothyronine nuclear receptor complex. This complex stimulates the formation, directly or indirectly, of a diversity of messenger RNA (mRNA) sequences. A generalized increase in mRNA as well as a disproportionate increase in a limited number of RNA sequences have been demonstrated. Regulation of thyroid hormone effects may be carried out largely at a local cellular level. Highly selective alterations in sensitivity to the triiodothyronine nuclear receptor complex may occur at specific target genes. Metabolic factors and hormones participate in such regulation. In a given tissue, alterations in the total number of receptor sites has not been shown to be useful as an index of thyroid hormone response, and local modulation of the response to the triiodothyronine receptor complex by a variety of factors other than triiodothyronine may be carried out at a postreceptor level.
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Cites
The action of thyroid hormones at the cell level
TATA, Jr., ERNSTER, L., LINDBERG, O., ARRHENIUS, E., PEDERSEN, S., & HEDMAN, R. (1963) · Biochemical Journal · doi:10.1042/bj0860408 · Cited by 528
OPPENHEIMER, J. H., SCHWARTZ, H. L., & SURKS, M. I. (1974) · Endocrinology · doi:10.1210/endo-95-3-897 · Cited by 466
Self-citationRibonucleic acid synthesis during the early action of thyroid hormones
Tata, Jr., & Widnell, C. (1966) · Biochemical Journal · doi:10.1042/bj0980604 · Cited by 400
BERMUDEZ, F., SURKS, M. I., & OPPENHEIMER, J. H. (1975) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-41-1-27 · Cited by 375
Self-citationRegulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones.
MARTIAL, J. A., Baxter, J. D., Goodman, H. M., & Seeburg, P. H. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.5.1816 · Cited by 342
SPECIFIC NUCLEAR TRIIODOTHYRONINE BINDING SITES IN RAT LIVER AND KIDNEY1
OPPENHEIMER, J. H., KOERNER, D., SCHWARTZ, H. L., & SURKS, M. I. (1972) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-35-2-330 · Cited by 340
Self-citationMechanisms and regulation of biosynthesis of saturated fatty acids.
Volpe, J. J., & Vagelos, P. R. (1976) · Physiological Reviews · doi:10.1152/physrev.1976.56.2.339 · Cited by 339
Iodothyronine Metabolism in Rat Liver Homogenates
Kaplan, M. M., & Utiger, R. D. (1978) · Journal of Clinical Investigation · doi:10.1172/jci108957 · Cited by 312
Portnay, G. I., O'Brian, J. T., Bush, J., Vagenakis, A. G., Azizi, F., Arky, R. A., Ingbar, S. H., & Braverman, L. E. (1974) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-39-1-191 · Cited by 252
Mechanism of Thyroid Calorigenesis: Role of Active Sodium Transport
Ismail-Beigi, F., & Edelman, I. S. (1970) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.67.2.1071 · Cited by 242
Cited by
Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.1.0455 · Cited by 1,853
Deiodinases: implications of the local control of thyroid hormone action
Bianco, A. C., & Kim, B. W. (2006) · Journal of Clinical Investigation · doi:10.1172/jci29812 · Cited by 845
Thyroid hormone and the cardiovascular system
Klein, I. (1990) · The American Journal of Medicine · doi:10.1016/0002-9343(90)90531-h · Cited by 370
Evolution of the Knowledge of Free Radicals and Other Oxidants
Di Meo, S., & Venditti, P. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/9829176 · Cited by 367
Thyroid-Pituitary Interaction: Feedback Regulation of Thyrotropin Secretion by Thyroid Hormones
Bleich, H. L., Moore, M. J., & Larsen, P. R. (1982) · New England Journal of Medicine · doi:10.1056/nejm198201073060107 · Cited by 357
Metadata
- Authors
- Oppenheimer, J. H.
- Venue
- Science
- Published
- 1979-03-09
- Volume
- 203
- Issue
- 4384
- Pages
- 971-979
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1979933243
- Cited by
- 502
- References
- 55
- FWCI
- 37.61
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
