The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
A MID-DAY SURGE IN CORTISOL LEVELS
Abstract
A dramatic mid-day surge of cortisol with its onset concomitant with food intake was observed. Cortisol levels were unaffected by the evening meal. The magnitude and time course of the initiation of this mid-day peak of cortisol are markedly attenuated by food deprivation. These observations establish that within the circadian periodicity there exists a mid-day rhythm of cortisol secretion which appears to be synchronized by food intake.
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“Ingestion of glucose, amino acids, protein, or mixed meals tends to increase serum and salivary cortisol concentrations in healthy adults (1–8).”
From Glucose ingestion selectively amplifies ACTH and cortisol secretory-burst mass and enhances their joint synchrony in healthy men. (2011) · cites this paper as [2]
Citations
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A Diurnal Rhythm in the Excretion of Urinary Ketosteroids by Young Men1
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Light Synchronization of the Circadian Rhythm in Plasma Cortisol (17-OHCS) Concentration in Man
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“In addition to diurnal variations in circulating glucocorticoid hormone levels (high in the morning, low at night), it is well known that levels increase following the ingestion of a meal [1].”
BackgroundInfluentialDelta-sleep-inducing peptide does not affect CRH and meal-induced ACTH and cortisol secretion
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Le syndrome de Cushing alimentaire: une nouvelle entité d'hypercorticisme organique
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“, 1981a) and cortisol (Quigley and Yen, 1979; Follenius et al., 1982) with feeding is synchronous in normal subjects and pregnant women (Quigley et al.”
BackgroundEffects of Cyclic and Continuous Total Enteral Nutrition on Circadian Cortisol Rhythm
Hideo, K. A. T. O., Saito, M., Shimazu, T., Ogase, H., & Tanioka, H. (1987) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.2.83 · Cited by 3
“Utilizing frequent blood sampling at 10 min intervals or less, several authors [9, 10, 12] demonstrated that meal intake causes a rapid but rather transient rise of plasma cortisol.”
BackgroundMinors, D. S., & Waterhouse, J. M. (1981) · Elsevier eBooks · doi:10.1016/b978-0-7236-0592-8.50018-1 · Cited by 3
Jacobs, G. E., Hulskotte, E. G. J., de Kam, M. L., Zha, G., Jiang, J., Hu, P., Zhao, Q., PELT, J. V., Goekoop, J. G., Zitman, F. G., et al. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2010.06.009 · Cited by 2
“This midday cortisol release is augmented by food intake only during the afternoon but not during the eveningmeal (Follenius et al., 1982; Quigley and Yen, 1979).”
Circadian rhythm and stress in the elderly: A study using salivary cortisol levels as an indicator.
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Plasma cortisol concentrations in women with menopausal flushes
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“In adults, plasma cortisol levels increase postprandially [43,44].”
Miyake, A., Yoshimoto, Y., Kawamura, Y., Aono, T., Tanizawa, O., Shinomura, Y., Himeno, S., & Tarui, S. (1988) · Endocrinologia Japonica · doi:10.1507/endocrj1954.35.647 · Cited by 1
“Ingestion of lunch is known to cause acute release of PRL and cortisol in normal women (Quigley and Yen 1979; Quigley et al., 1981; Ishizuka et al., 1983), pregnant women (Quigley et al.”
BackgroundMetabolic approach to atherosclerosis: Effect of gliclazide
Brindley, D. N. (1992) · Metabolism · doi:10.1016/0026-0495(92)90089-s · Cited by 1
Nycthemeral Changes in Plasma Cortisol Levels in Preruminant Calves with Different Milk Proteins
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CIRCADIAN RHYTHM OF PLASMA ALDOSTERONE IN OLDER PATIENTS WITH DEMENTIA UNDER FORCED BED REST
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Change in circadian cortisol rhythmicity in patients with intracranial tumour
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“Using this approach, a full evaluation of ultradian secretion is precluded, but the interference of peaks evoked by meals (6,7) is avoided.”
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Mastorakos, G. P., & Antoniou-Tsigkos, A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99422-4 · Cited by 1
Nagel, R., Kaiser, S., Stainfield, C., Toscani, C., Fox‐Clarke, C., Paijmans, A. J., Castro, C. C., Vendrami, D. L. J., Forcada, J., & Hoffman, J. I. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.08.463664 · Cited by 1
“On the other hand, circulating levels of cortisol are essential for the maintenance of metabolic functions (Kuo et al. 2015), and food-induced cortisol secretions have been documented in the literature (Quigley and Yen 1979; Gibson et al. 1999; Stimson et al. 2014).”
BackgroundThe Adrenal Cortex and its Disorders
Miller, W. L. (2005) · Clinical Pediatric Endocrinology · doi:10.1002/9780470987117.ch15 · Cited by 2
Kaseva, N. (2014) · Työväentutkimus Vuosikirja
Cortisol Responses to Meals in Human Subjects Living without Time Cues
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Meinel, J. A., Haverkamp, T., Wünsche, F., & Richter-Unruh, A. (2020) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-1217-7169
The impact of psychosocial stress and biological sex on false recognition memory
Henry, M. (2010) · Open University of Cape Town (University of Cape Town)
Ho, J. T. (2007) · Adelaide Research & Scholarship (AR&S) (University of Adelaide)
Liu, D., Tian, P., Hou, Y., Zhang, T., Lu, Y., Ren, L., Wang, C., & Song, G. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1760358
“As early as 1979, researchers observed that plasma cortisol levels rise after eating, particularly after lunch, with peak levels typically occurring within one hour post-meal (20, 21).”
Metadata
- Authors
- QUIGLEY, M. E., & YEN, S. S. C.
- Affiliations
- National Institutes of Health (US)
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 1979-12
- Volume
- 49
- Issue
- 6
- Pages
- 945-947
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2049002632
- Cited by
- 135
- References
- 8
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2022: 2 · 2021: 4 · 2020: 2 · 2019: 3 · 2018: 1 · 2017: 1 · 2015: 1 · 2014: 3 · 2013: 1 · 2012: 1
- FWCI
- 2.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Keywords
- cortisol, circadian rhythm, dietary intake, food deprivation, cortisol secretion, meal timing, circadian synchronization
- MeSH terms
- Adult, Circadian Rhythm, Eating, Fasting, Female, Humans, Hydrocortisone
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