Growth hormone deficiency in adulthood and the effects of growth hormone replacement: a review

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1. Acute effects of somatomammotropin hormones on neuronal components of the hypothalamic-pituitary-gonadal axis
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2. Irisin and Secondary Osteoporosis in Humans
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3. Clinical features of GH deficiency and effects of 3 years of GH replacement in adults with controlled Cushing's disease
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4. The value of IGF1 estimation in adults with GH deficiency
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5. Treatment of adult growth hormone deficiency with human recombinant growth hormone: an update on current evidence and critical review of advantages and pitfalls
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6. Additional Beneficial Effects of Alendronate in Growth Hormone (GH)-Deficient Adults with Osteoporosis Receiving Long-Term Recombinant Human GH Replacement Therapy: A Randomized Controlled Trial
   Nienke Ruurdje Biermasz, Neveen A. T. Hamdy, Yvonne J. H. Janssen, Ferdinand Roelfsema · 2001 · The Journal of Clinical Endocrinology & Metabolism
7. Gender difference in the response of growth hormone (GH)-deficient adults to GH therapy
   Frances J. Hayes, Tarek M. Fiad, T. Joseph McKenna · 1999 · Metabolism
8. Analysis of short- and long-term metabolic effects of growth hormone replacement therapy in adult patients with craniopharyngioma and non-functioning pituitary adenoma
   Eriselda Profka, Claudia Giavoli, S. Bergamaschi, Emanuele Ferrante, Elena Malchiodi, Elisa Sala, Elisa Verrua, Giulia Rodari, Marcello Filopanti, P. Beck‐Peccoz et al. · 2014 · Journal of Endocrinological Investigation
9. Comparative results of a 4-year study on cardiovascular parameters, lipid metabolism, body composition and bone mass between untreated and treated adult growth hormone deficient patients
   Hugo L Fideleff, Hugo Boquete, Graciela Stalldecker, Ana Giaccio, Patricia G. V. Sobrado · 2008 · Growth Hormone & IGF Research
10. Impact of GH substitution on exercise capacity and muscle strength in GH‐deficient adults: a meta‐analysis of blinded, placebo‐controlled trials
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11. Controversies Regarding the Effects of Growth Hormone on the Heart
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12. Growth Hormone and Sport
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13. Pituitary Function and Functional Outcome in Adults after Severe Traumatic Brain Injury: The Long-Term Perspective
    Trandur Ulfarsson, Gudni Arnar Gudnason, Thord Rosén, Christian Blomstrand, Katharina Stibrant Sunnerhagen, Åsa Lundgren‐Nilsson, Michael Nilsson · 2012 · Journal of Neurotrauma
14. Biochemical Markers of Individual Response to Growth Hormone Replacement in Adults
    John P. Monson · 2001 · Hormone Research in Paediatrics
15. Hypothalamic-Pituitary Dysfunction Following Traumatic Brain Injury Affects Functional Improvement During Acute Inpatient Rehabilitation
    Emily Rose Rosario, Rubina Aqeel, Meghan A. Brown, Gabriel Sanchez, Colleen Moore, David P. Patterson · 2012 · Journal of Head Trauma Rehabilitation
16. Ventilation threshold as a measure of impaired physical performance in adults with growth hormone excess
    Scott Gordon Thomas, Linda June Woodhouse, Sonia M. C. Pagura, Shereen Ezzat · 2002 · Clinical Endocrinology
17. Central growth hormone signaling is not required for the timing of puberty
    Tabata Mariz Bohlen, Thais T. Zampieri, Isadora C. Furigo, Pryscila D. S. Teixeira, Edward Owen List, John Joseph Kopchick, José Donato, Renata Frazão · 2019 · Journal of Endocrinology
18. Baseline characteristics and response to GH replacement of hypopituitary patients previously irradiated for pituitary adenoma or craniopharyngioma: data from the Pfizer International Metabolic Database
    Dominique M. Maiter, Roger Abs, Gudmundur Johannsson, MF Scanlon, P J Jönsson, Patrick Wilton, M Koltowska-Häggström · 2006 · European Journal of Endocrinology
19. Using EQ-5D to Derive General Population-based Utilities for the Quality of Life Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA)
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20. Sex Differences in Somatotrope Dependency on Leptin Receptors in Young Mice: Ablation of LEPR Causes Severe Growth Hormone Deficiency and Abdominal Obesity in Males
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21. Re‐assessment of growth hormone secretion in young adult patients with childhood‐onset growth hormone deficiency
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22. Exercise Training Benefits Growth Hormone (GH)-Deficient Adults in the Absence or Presence of GH Treatment
    Scott Gordon Thomas, John G. Esposito, Shereen Ezzat · 2003 · The Journal of Clinical Endocrinology & Metabolism
23. Impact of Long-Term Growth Hormone Replacement Therapy on Metabolic and Cardiovascular Parameters in Adult Growth Hormone Deficiency: Comparison Between Adult and Elderly Patients
    Elisabetta Scarano, Enrico Riccio, Teresa Somma, Rossana Arianna, Fiammetta Romano, Elea Di Benedetto, Giulia de Alteriis, Annamaria Colao, Carolina Di Somma · 2021 · Frontiers in Endocrinology
24. High IGFBP2 levels are not only associated with a better metabolic risk profile but also with increased mortality in elderly men
    Annewieke W. van den Beld, W. F. P. Blum, Michael P. Brugts, J. A. M. J. L. Janssen, Diederick E. Grobbee, S.W.J. Lamberts · 2012 · European Journal of Endocrinology
25. Growth hormone replacement therapy regulates microRNA-29a and targets involved in insulin resistance
    Artur Galimov, Angelika Hartung, Roman Trepp, Alexander Mader, Martin Flück, Axel Linke, Matthias Blüher, Emanuel Christ, Jan Krützfeldt · 2015 · Journal of Molecular Medicine
26. Chapter 3 Diseases Associated with Growth Hormone‐Releasing Hormone Receptor (GHRHR) Mutations
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27. MANAGEMENT OF PITUITARY INCIDENTALOMAS
    Trevor A. Howlett, Julie Como, David Clark Aron · 2000 · Endocrinology and Metabolism Clinics of North America
28. Growth hormone (GH) replacement therapy in GH deficient adults: Predictors of one-year metabolic and clinical response
    Johan Svensson, Nick Finer, Pierre Marc Bouloux, John Stuart Bevan, Björn Jönsson, Anders F. Mattsson, Mikael Lundberg, Philip E. Harris, Maria Kołtowska‐Häggström, John P. Monson · 2007 · Growth Hormone & IGF Research
29. Effects of Growth Hormone Secretion on Body Composition in Patients with Crohn’s Disease
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30. Clinical Aspects of Growth Hormone Deficiency in Adults
    Jens Otto Lunde Jørgensen, Jens Sandahl Christiansen · 2005 · KARGER eBooks
31. Commencing growth hormone replacement in adults with a fixed low dose. Effects on serum lipoproteins, glucose metabolism, body composition, and cardiovascular function
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32. Effects of growth hormone replacement therapy on levels of cortisol and cortisol-binding globulin in hypopituitary adults
    M. Tschöp, Harald Lahner, H Feldmeier, Helmut Grasberger, Katherine Mary Morrison, Onno Eilard Janssen, AF Attanasio, C. J. Strasburger · 2000 · European Journal of Endocrinology
33. Late Life Metabolic Syndrome, Early Growth, and Common Polymorphism in the Growth Hormone and Placental Lactogen Gene Cluster
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34. Growth hormone (GH) andatherosclerosis: changes in morphology and function of major arteries during GH treatment
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35. The diagnosis of growth hormone deficiency (GHD) in successfully treated acromegalic patients
    R. D. Murray, SR Peacey, A. Rahim, Andy A. Toogood, Michael O. Thorner, Stephen Michael Shalet · 2001 · Clinical Endocrinology
36. Effects of recombinant mouse growth hormone treatment on growth and body composition in GHRH knock out mice
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37. Survivors of childhood cancer: long‐term edocrine and metabolic problems dwarf the growth distrubance
    RD Murray, Bernadette M. D. Brennan, A Rahim, Stephen Michael Shalet · 1999 · Acta Paediatrica
38. Effect of Growth Hormone (GH) and/or Testosterone Replacement on the Prostate in GH-Deficient Adult Patients
    Annamaria Colao, Carolina Di Somma, Stefano Spiezia, Mariagiovanna Filippella, Rosario Pivonello, Gaetano Lombardi · 2003 · The Journal of Clinical Endocrinology & Metabolism
39. Atherogenic lipoprotein phenotype and low-density lipoprotein size and subclasses in patients with growth hormone deficiency before and after short-term replacement therapy
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40. Hormonal Regulation of Growth and Metabolic Effects of Growth Hormone
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41. Nonalcoholic fatty liver disease and metabolic syndrome in hypopituitary patients
    Nyenwe, Ebenezer A., Williamson-Baddorf, Sarah, Waters, Bradford, Wan, Jim Y., Solomon, Solomon S. · 2009 · The American Journal of the Medical Sciences
42. Symptoms of gonadal dysfunction are more predictive of hypopituitarism than nonspecific symptoms in screening for pituitary dysfunction following moderate or severe traumatic brain injury
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43. One Year of Yoga Training Alters Ghrelin Axis in Centrally Obese Adults With Metabolic Syndrome
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44. Can a glucagon stimulation test characterized by lower GH cut-off value be used for the diagnosis of growth hormone deficiency in adults?
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45. Recovery of growth hormone secretion following cabergoline treatment of macroprolactinomas
    Lindsay George, N. Nicolau, MF Scanlon, Jeffrey S. Davies · 2000 · Clinical Endocrinology
46. Effect of growth-hormone therapy on early atherosclerotic changes in GH-deficient adults
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47. The Future of Doping Control in Athletes
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48. Providing Quality Care in Childhood Cancer Survivorship: Learning From the Past, Looking to the Future
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49. Relationship between GH-induced metabolic changes and changes in body composition: A dose and time course study in GH-deficient adults
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50. Growth hormone (GH) status is an independent determinant of serum levels of cholesterol and triglycerides in healthy adults
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51. Diagnosis of GH Deficiency in Adults--How Good Do the Criteria Need to Be?
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52. Efficacy and safety of growth hormone (GH) in the treatment of adult Japanese patients with GH deficiency: A randomised, placebo-controlled study
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53. Low-dose GH improves exercise capacity in adults with GH deficiency: effects of a 22-month placebo-controlled, crossover trial
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54. Growth hormone ( GH ) enhances anaerobic capacity: impact on physical function and quality of life in adults with GH deficiency
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55. THERAPY OF ENDOCRINE DISEASE: GH therapy in adult GH deficiency: A review of treatment schedules and the evidence for low starting doses
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56. Effect of GH on human skeletal muscle lipid metabolism in GH deficiency
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57. Differential Effects of GH Replacement on the Components of the Leptin System in GH-Deficient Individuals
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58. Diagnosis of growth hormone deficiency in adults by testing with GHRP-6 alone or in combination with GHRH: comparison with the insulin tolerance test
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59. Growth hormone: current and future therapeutic applications
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60. Growth hormone (GH) replacement in hypopituitary adults with GH deficiency evaluated by a utility‐weighted quality of life index: a precursor to cost–utility analysis
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61. Dermatoendokrinologie
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62. Effects of Growth Hormone (GH) Replacement Therapy on Low-Density Lipoprotein Apolipoprotein B100 Kinetics in Adult Patients with GH Deficiency: A Stable Isotope Study
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63. High Risk of Adrenal Insufficiency in Adults Previously Treated for Idiopathic Childhood Onset Growth Hormone Deficiency
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64. The Impact of Pituitary Adenoma on Morbidity
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65. Diagnosis of adult GH deficiency
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66. Clinical predictors of GH deficiency in surgically cured acromegalic patients
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67. Bone density and turnover in young adult patients with growth hormone deficiency after 2-year growth hormone replacement according with gender
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68. Growth hormone (GH) replacement in GH-deficient adults: a crossover trial comparing the effect on metabolic control, well-being and compliance of three injections per week versus daily injections
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69. Trends In Growth Hormone Stimulation Testing And Growth Hormone Dosing In Adult Growth Hormone Deficiency Patients: Results From The Answer Program
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70. Growth Hormone Improves Cardiopulmonary Capacity and Body Composition in Children With Growth Hormone Deficiency
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71. Effects of Recombinant Growth Hormone on Visceral Fat Accumulation: Pilot Study in Human Immunodeficiency Virus-Infected Adolescents
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72. Polysomnographic findings in five adult patients with pituitary insufficiency before and after cessation of human growth hormone replacement therapy
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73. Effect of growth hormone replacement therapy on plasma lecithin:cholesterol acyltransferase and lipid transfer protein activities in growth hormone-deficient adults
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74. Measurement of growth hormone, insulin-like growth factor I and their binding proteins: the clinical aspects
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75. Current Guidelines for Adult GH Replacement
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76. Risk factors for osteoporosis in long-term survivors of intracranial germ cell tumors
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77. Effects of 3-year GH replacement therapy on bone mineral density in younger and elderly adults with adult-onset GH deficiency
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78. Ablation of Leptin Signaling to Somatotropes: Changes in Metabolic Factors that Cause Obesity
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79. The Placental Variant of Human Growth Hormone Reduces Maternal Insulin Sensitivity in a Dose-Dependent Manner in C57BL/6J Mice
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80. Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli
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81. Carotid artery intima-media thickness and lipid profile in adults with growth hormone deficiency after long-term growth hormone replacement
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82. GH and IGF‐I deficiency are associated with reduced loss of fat mass after laparoscopic‐adjustable silicone gastric banding
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83. Sweat secretion rates in growth hormone disorders
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84. Occurrence of GH deficiency in adult patients who underwent neurosurgery in the hypothalamus–pituitary area for non-functioning tumour masses
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85. Dyslipidaemia in Adult Growth Hormone (GH) Deficiency and the Effect of GH Replacement Therapy: A Review
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86. Hexarelin as a test of pituitary reserve in patients with pituitary disease
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87. Short- and Long-Term Effects of Growth Hormone (GH) Replacement on Protein Metabolism in GH-Deficient Adults
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88. Prevalence, natural history and consequences of posttraumatic hypopituitarism: A case for endocrine surveillance
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89. Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement
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90. Is further evaluation for growth hormone (GH) deficiency necessary in fibromyalgia patients with low serum insulin-like growth factor (IGF)-I levels?
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91. Metabolic Co-Morbidities Revealed in Patients with Childhood-Onset Adult GH Deficiency after Cessation of GH Replacement Therapy for Short Stature
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92. Partial Reversibility of Growth Hormone (GH) Deficiency in the GH-Releasing Hormone (GHRH) Knockout Mouse by Postnatal Treatment with a GHRH Analog
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93. Effects of two years of growth hormone (GH) replacement therapy on bone metabolism and mineral density in childhood and adulthood onset GH deficient patients
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94. Leptin Concentrations in GH Deficiency: The Effect of GH Insensitivity
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95. Growth hormone and the risk of atherosclerosis in growth hormone-deficient children
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96. Pituitary adenomas and cerebrovascular disease: A review on pathophysiology, prevalence, and treatment
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97. Effects of Growth Hormone Replacement Therapy on Bone Mineral Density in Growth Hormone Deficient Adults: A Meta-Analysis
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98. Protons vs Photons for Brain and Skull Base Tumors
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99. The Effect of Acclydine in Chronic Fatigue Syndrome: A Randomized Controlled Trial
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100. Serum IGF-1 concentrations in a sample of patients with traumatic brain injury as a diagnostic marker of growth hormone secretory response to glucagon stimulation testing
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