The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Melissa officinalis L. essential oil: antitumoral and antioxidant activities
Abstract
Melissa officinalis L (lemon balm) is a traditional herbal medicine used widely as a mild sedative, spasmolytic and antibacterial agent. This paper focuses on the analysis of the chemical composition and the biological activities of M. officinalis essential oil obtained under controlled harvesting and drying conditions. An in-vitro cytotoxicity assay using MTT indicated that this oil was very effective against a series of human cancer cell lines (A549, MCF-7, Caco-2, HL-60, K562) and a mouse cell line (B16F10). This oil possessed antioxidant activity, as evidenced by reduction of 1,1-diphenyl-2-picryl-hydrazyl (DPPH). These results pointed to the potential use of M. officinalis essential oil as an antitumoral agent.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Kapadia, G. J., Azuine, M. A., Tokuda, H., Takasaki, M., Mukainaka, T., Konoshima, T., & Nishino, H. (2002) · Pharmacological Research · doi:10.1006/phrs.2002.0992 · Cited by 238
Cited by
Biological effects of essential oils—A review
Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008) · Food and Chemical Toxicology · doi:10.1016/j.fct.2007.09.106 · Cited by 7,929
Dhifi, W., Bellili, S., Jazi, S., Bahloul, N., & Mnif, W. (2016) · Medicines · doi:10.3390/medicines3040025 · Cited by 1,308
Terpenoids as Plant Antioxidants
Graßmann, J. (2005) · Vitamins & Hormones · doi:10.1016/s0083-6729(05)72015-x · Cited by 465
Melissa officinalis L. – A review of its traditional uses, phytochemistry and pharmacology
Shakeri, A., Sahebkar, A., & Javadi, B. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.05.010 · Cited by 386
Herman, A., & Herman, A. P. (2015) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12334 · Cited by 338
Metadata
- Authors
- de Sousa, A. C., Alviano, D. S., Blank, A. F., Alves, P. B., Alviano, C. S., & Gattass, C. R.
- Venue
- Journal of Pharmacy and Pharmacology
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-05-01
- Volume
- 56
- Issue
- 5
- Pages
- 677-681
- ISSN
- 0022-3573 (ISSN-L)
- 2042-7158
- OpenAlex
- W2092595655
- Cited by
- 216
- References
- 1
- FWCI
- 10.76
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Melissa officinalis L. essential oil: antitumoral and antioxidant activities. https://app.cochat.ai/papers/10.1211/0022357023321
- The paper
- de Sousa, A. C., Alviano, D. S., Blank, A. F., Alves, P. B., Alviano, C. S., & Gattass, C. R. (2004). Melissa officinalis L. essential oil: antitumoral and antioxidant activities. Journal of Pharmacy and Pharmacology. https://doi.org/10.1211/0022357023321
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
