Cited by 850Multiple Sclerosis Research StudiesPeripheral Neuropathies and DisordersOcular Diseases and Behçet’s Syndrome

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Distinction between MOG antibody-positive and AQP4 antibody-positive NMO spectrum disorders

Open access

Sato, Douglas Kazutoshi, Callegaro, Dagoberto, Lana-Peixoto, Marco Aurelio, Waters, Patrick J., Jorge, Frederico M. de Haidar, Takahashi, Toshiyuki, Nakashima, Ichiro, Apostolos-Pereira, Samira Luisa, Talim, Natalia, Simm, Renata Faria, Lino, Angelina Maria Martins, Misu, Tatsuro, Leite, Maria Isabel, Aoki, Masashi, Fujihara, Kazuo·2014·Neurology

DOI 10.1212/wnl.0000000000000101PMC PMC3937859

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVE: To evaluate clinical features among patients with neuromyelitis optica spectrum disorders (NMOSD) who have myelin oligodendrocyte glycoprotein (MOG) antibodies, aquaporin-4 (AQP4) antibodies, or seronegativity for both antibodies. METHODS: Sera from patients diagnosed with NMOSD in 1 of 3 centers (2 sites in Brazil and 1 site in Japan) were tested for MOG and AQP4 antibodies using cell-based assays with live transfected cells. RESULTS: Among the 215 patients with NMOSD, 7.4% (16/215) were positive for MOG antibodies and 64.7% (139/215) were positive for AQP4 antibodies. No patients were positive for both antibodies. Patients with MOG antibodies represented 21.1% (16/76) of the patients negative for AQP4 antibodies. Compared with patients with AQP4 antibodies or patients who were seronegative, patients with MOG antibodies were more frequently male, had a more restricted phenotype (optic nerve more than spinal cord), more frequently had bilateral simultaneous optic neuritis, more often had a single attack, had spinal cord lesions distributed in the lower portion of the spinal cord, and usually demonstrated better functional recovery after an attack. CONCLUSIONS: Patients with NMOSD with MOG antibodies have distinct clinical features, fewer attacks, and better recovery than patients with AQP4 antibodies or patients seronegative for both antibodies.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1212/wnl.0000000000000101

Cites

21 of 21 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Revised diagnostic criteria for neuromyelitis optica
Wingerchuk, D. M., Lennon, V. A., Pittock, S. J., Lucchinetti, C. F., & Weinshenker, B. G. (2006) · Neurology · doi:10.1212/01.wnl.0000216139.44259.74 · Cited by 2,568
The spectrum of neuromyelitis optica
Wingerchuk, D. M., Lennon, V. A., Lucchinetti, C. F., Pittock, S. J., & Weinshenker, B. G. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70216-8 · Cited by 2,182
The clinical course of neuromyelitis optica (Devic’s syndrome)
Wingerchuk, D. M., Hogancamp, W. E., O’Brien, P. C., & Weinshenker, B. G. (1999) · Neurology · doi:10.1212/wnl.53.5.1107 · Cited by 1,819
Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre
Takahashi, T., Fujihara, K., Nakashima, I., Misu, T., Miyazawa, I., Nakamura, M., Watanabe, S., Shiga, Y., Kanaoka, C., Fujimori, J., et al. (2007) · Brain · doi:10.1093/brain/awm062 · Cited by 633
Neuromyelitis Optica Spectrum Disorders With Aquaporin-4 and Myelin-Oligodendrocyte Glycoprotein Antibodies: A Comparative Study
Kitley, J., Waters, P., Woodhall, M., Leite, M. I., Murchison, A., George, J., Küker, W., Chandratre, S., Vincent, A., & Palace, J. (2014) · JAMA Neurology · doi:10.1001/jamaneurol.2013.5857 · Cited by 597
Serologic diagnosis of NMO: A multicenter comparison of aquaporin-4-IgG assays
Waters, P. J., McKeon, A., Leite, M. I., Rajasekharan, S., Lennon, V. A., Villalobos, A., Palace, J., Mandrekar, J. N., Vincent, A., Bar-Or, A., et al. (2012) · Neurology · doi:10.1212/wnl.0b013e318248dec1 · Cited by 526
Self-citation
Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
Mader, S., Gredler, V., Schanda, K., Rostasy, K. M., Dujmović, I., Pfaller, K., Lutterotti, A., Jarius, S., Pauli, F. D., Kuenz, B., et al. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-184 · Cited by 449
Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype
Kitley, J., Woodhall, M., Waters, P., Leite, M. I., Devenney, E., Craig, J., Palace, J., & Vincent, A. (2012) · Neurology · doi:10.1212/wnl.0b013e31826aac4e · Cited by 445
Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein
O’Connor, K. C., McLaughlin, K. A., Jager, P. L. D., Chitnis, T., Bettelli, E., Xu, C., Robinson, W. H., Cherry, S. V., Bar‐Or, A., Banwell, B., et al. (2007) · Nature Medicine · doi:10.1038/nm1488 · Cited by 419
The spectrum of MOG autoantibody-associated demyelinating diseases
Reindl, M., Pauli, F. D., Rostasy, K. M., & Berger, T. (2013) · Nature Reviews Neurology · doi:10.1038/nrneurol.2013.118 · Cited by 376

Show all 21 references

Sorted by citations

Items 201–300 of 848

Immunopathophysiology of pediatric CNS inflammatory demyelinating diseases
Bar‐Or, A., Hintzen, R. Q., Dale, R. C., Rostasy, K. M., Brück, W., & Chitnis, T. (2016) · Neurology · doi:10.1212/wnl.0000000000002821 · Cited by 49
A case of MOG antibody-positive bilateral optic neuritis and meningoganglionitis following a genital herpes simplex virus infection
Nakamura, M., Iwasaki, Y., Takahashi, T., Kaneko, K., Nakashima, I., Kunieda, T., Kaneko, S., & Kusaka, H. (2017) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2017.07.023 · Cited by 50
Injectable Hydrogels for Spinal Cord Repair: A Focus on Swelling and Intraspinal Pressure
Khaing, Z. Z., Ehsanipour, A., Hofstetter, C. P., & Seidlits, S. K. (2016) · Cells Tissues Organs · doi:10.1159/000446697 · Cited by 51
Clinical and laboratory features distinguishing MOG antibody disease from multiple sclerosis and AQP4 antibody-positive neuromyelitis optica
Ciotti, J. R., Eby, N. S., Wu, G. F., Naismith, R. T., Chahin, S., & Cross, A. H. (2020) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2020.102399 · Cited by 52
Neuromyelitis optica spectrum disorders
Paul, S. A., Mondal, G. P., Bhattacharyya, R., Ghosh, K. C., & Bhat, I. A. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117225 · Cited by 51
Anti-MOG antibodies with longitudinally extensive transverse myelitis preceded by CLIPPERS
Symmonds, M., Waters, P. J., Küker, W., Leite, M. I., & Schulz, U. G. (2015) · Neurology · doi:10.1212/wnl.0000000000001370 · Cited by 49
B Cells and Autoantibodies in Multiple Sclerosis
Pröbstel, A., Sanderson, N., & Derfuss, T. J. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160716576 · Cited by 50
Radiological characteristics of myelin oligodendrocyte glycoprotein antibody disease
Salama, S., Khan, M., Levy, M., & Izbudak, I. (2019) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2019.01.021 · Cited by 48
Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study
Olesen, M. N., Soelberg, K. K., Debrabant, B., Nilsson, A. C., Lillevang, S. T., Grauslund, J., Brandslund, I., Madsen, J. S., Paul, F., Smith, T. J., et al. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1440-5 · Cited by 51
Classification algorithms with multi-modal data fusion could accurately distinguish neuromyelitis optica from multiple sclerosis
Eshaghi, A., Riyahi-Alam, S., Saeedi, R., Roostaei, T., Nazeri, A., Aghsaei, A., Doosti, R., Ganjgahi, H., Bodini, B., Shakourirad, A., et al. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2015.01.001 · Cited by 47
Association of circulating follicular helper T cells with disease course of NMO spectrum disorders
Li, Y.-J., Zhang, F., Qi, Y., Chang, G., Fu, Y., Su, L., Shen, Y., Sun, N., Borazanci, A., Yang, C., et al. (2014) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2014.11.011 · Cited by 49
Clinical characteristics and outcomes of myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis in varying age groups: A cohort study in China
Song, H., Zhou, H., Yang, M. C., Xu, Q., Sun, M., & Wei, S. (2019) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2019.03.014 · Cited by 47
Review: Recent advances in the understanding of the pathophysiology of neuromyelitis optica spectrum disorder
Chang, V. T. W., & Chang, H. (2019) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12574 · Cited by 52
Macrophages and Autoantibodies in Demyelinating Diseases
Koike, H., & Katsuno, M. (2021) · Cells · doi:10.3390/cells10040844 · Cited by 49
Clinical spectrum of central nervous system myelin oligodendrocyte glycoprotein autoimmunity in adults
Cobo‐Calvo, Á., Vukusic, S., & Marignier, R. (2019) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000681 · Cited by 46
Pathology of myelin oligodendrocyte glycoprotein antibody-associated disease: a comparison with multiple sclerosis and aquaporin 4 antibody-positive neuromyelitis optica spectrum disorders
Takai, Y., Misu, T., Fujihara, K., & Aoki, M. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1209749 · Cited by 50
Isolated new onset ‘atypical’ optic neuritis in the NMO clinic: serum antibodies, prognoses and diagnoses at follow-up
Piccolo, L., Woodhall, M. R., Tackley, G., Juryńczyk, M., Kong, Y., Domingos, J., Gore, R., Vincent, A. C., Waters, P. J., Leite, M. I., et al. (2015) · Journal of Neurology · doi:10.1007/s00415-015-7983-1 · Cited by 48
Gender effect on neuromyelitis optica spectrum disorder with aquaporin4-immunoglobulin G
Kim, S., Waters, P. J., Woodhall, M. R., Kim, Y., Kim, J.-A., Cheon, S. Y., Lee, S., Jo, S. R., Kim, D., Jung, K. C., et al. (2016) · Multiple Sclerosis Journal · doi:10.1177/1352458516674366 · Cited by 43
Neuromyelitis optica and neuromyelitis optica spectrum disorders
Marignier, R., Cobo Calvo, A., & Vukusic, S. (2017) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000455 · Cited by 45
Multiple sclerosis, and other demyelinating and autoimmune inflammatory diseases of the central nervous system
Matute‐Blanch, C., Montalbán, X., & Comabella, M. (2017) · Handbook of clinical neurology · doi:10.1016/b978-0-12-804279-3.00005-8 · Cited by 45
MOG-Enzephalomyelitis: Internationale Empfehlungen zu Diagnose und Antikörpertestung
Jarius, S., Paul, F., Aktaş, O., Asgari, N., Dale, R. C., Seze, J. D., Franciotta, D. M., Fujihara, K., Jacob, A., Kim, H. J., et al. (2018) · Der Nervenarzt · doi:10.1007/s00115-018-0607-0 · Cited by 44
Relapsing lumbosacral myeloradiculitis: An unusual presentation of MOG antibody disease
Sundaram, S., Nair, S. S., Jaganmohan, D., Unnikrishnan, G., & Nair, M. (2019) · Multiple Sclerosis Journal · doi:10.1177/1352458519840747 · Cited by 44
Neuromyelitis optica spectrum disorder (NMOSD): A new concept
Seze, J. D., Kremer, L. D., & Collongues, N. (2016) · Revue Neurologique · doi:10.1016/j.neurol.2016.03.003 · Cited by 46
Diagnosis and treatment of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis
Kezuka, T., & Ishikawa, H. (2018) · Japanese Journal of Ophthalmology · doi:10.1007/s10384-018-0561-1 · Cited by 43
Central vein sign and other radiographic features distinguishing myelin oligodendrocyte glycoprotein antibody disease from multiple sclerosis and aquaporin-4 antibody-positive neuromyelitis optica
Ciotti, J. R., Eby, N. S., Brier, M. R., Wu, G. F., Chahin, S., Cross, A. H., & Naismith, R. T. (2021) · Multiple Sclerosis Journal · doi:10.1177/13524585211007086 · Cited by 42
Antibody-related movement disorders – a comprehensive review of phenotype-autoantibody correlations and a guide to testing
Gövert, F., Leypoldt, F., Junker, R., Wandinger, K., Deuschl, G., Bhatia, K. P., & Balint, B. (2020) · Neurological Research and Practice · doi:10.1186/s42466-020-0053-x · Cited by 42
Brain structural and functional alterations in MOG antibody disease
Zhuo, Z., Duan, Y., Tian, D., Wang, X., Gao, C., Ding, J., Zheng, F., Zhang, T., Zhang, X., Barkhof, F., et al. (2020) · Multiple Sclerosis Journal · doi:10.1177/1352458520964415 · Cited by 42
Sjögren syndrome and neuromyelitis optica spectrum disorder co-exist in a common autoimmune milieu
de Carvalho, D. C., Tironi, T. D. S., Freitas, D. S., Kleinpaul, R. G. V., Talim, N. C., & Lana–Peixoto, M. A. (2014) · Arquivos de Neuro-Psiquiatria · doi:10.1590/0004-282x20140097 · Cited by 42
Pediatric Neuromyelitis Optica Spectrum Disorders
Gombolay, G. Y., & Chitnis, T. (2018) · Current Treatment Options in Neurology · doi:10.1007/s11940-018-0502-9 · Cited by 43
Imaging Approach to Myelopathy
Kranz, P. G., & Amrhein, T. J. (2018) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2018.09.006 · Cited by 42
Update on pediatric optic neuritis
Lock, J. H., Newman, N. J., Biousse, V., & Peragallo, J. H. (2019) · Current Opinion in Ophthalmology · doi:10.1097/icu.0000000000000607 · Cited by 39
The Balance in T Follicular Helper Cell Subsets Is Altered in Neuromyelitis Optica Spectrum Disorder Patients and Restored by Rituximab
Nicolas, P., Ruiz, A., Cobo-Calvo, Á., Fiard, G., Giraudon, P., Vukusic, S., & Marignier, R. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02686 · Cited by 35
Visualizing the Central Nervous System: Imaging Tools for Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Kuchling, J., & Paul, F. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00450 · Cited by 42
An update on optic neuritis
Kraker, J. A., & Chen, J. J.-W. (2023) · Journal of Neurology · doi:10.1007/s00415-023-11920-x · Cited by 47
Relapse activity in the chronic phase of anti-myelin-oligodendrocyte glycoprotein antibody-associated disease
Akaishi, T., Misu, T., Fujihara, K., Takahashi, T., Takai, Y., Nishiyama, S., Kaneko, K., Fujimori, J., Ishii, T., Aoki, M., et al. (2021) · Journal of Neurology · doi:10.1007/s00415-021-10914-x · Cited by 39
A Clinical Approach to the Differential Diagnosis of Multiple Sclerosis
Toledano, M., Weinshenker, B. G., & Solomon, A. J. (2015) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-015-0576-7 · Cited by 42
Neuromyelitis Optica Spectrum Disorders
Costello, F. (2022) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000001168 · Cited by 38
Neuromyelitis optica: a positive appraisal of seronegative cases
Bernard‐Valnet, R., Liblau, R., Vukusic, S., & Marignier, R. (2015) · European Journal of Neurology · doi:10.1111/ene.12679 · Cited by 40
Protective environmental factors for neuromyelitis optica
Graves, J. S., Grandhe, S., Weinfurtner, K. M., Krupp, L., Belman, A. L., Chitnis, T., Ness, J., Weinstock‐Guttman, B., Gorman, M., Patterson, M. C., et al. (2014) · Neurology · doi:10.1212/wnl.0000000000001001 · Cited by 38
What’s new in neuromyelitis optica? A short review for the clinical neurologist
Whittam, D. H., Wilson, M., Hamid, S. H. M., Keir, G., Bhojak, M., & Jacob, A. (2017) · Journal of Neurology · doi:10.1007/s00415-017-8445-8 · Cited by 41
Clinical time course of pediatric acute disseminated encephalomyelitis
Nishiyama, M., Nagase, H., Tomioka, K., Tanaka, T. J., Yamaguchi, H., Ishida, Y., Toyoshima, D., Fujita, K., Maruyama, A., Sasaki, K., et al. (2019) · Brain and Development · doi:10.1016/j.braindev.2019.02.011 · Cited by 38
Understanding Childhood Neuroimmune Diseases of the Central Nervous System
Matricardi, S., Farello, G., Savasta, S., & Verrotti, A. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00511 · Cited by 40
Neuromyelitis optica spectrum disorder: pregnancy-related attack and predictive risk factors
Wang, L., Zhou, L., ZhangBao, J., Huang, W., Chang, X., Lü, C., Wang, M., Li, W., Xia, J., Li, X., et al. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-323982 · Cited by 37
Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey
Nakamura, M., Ogawa, R., Fujimori, J., Uzawa, A., Sato, Y., Nagashima, K., Kuriyama, N., Kuwabara, S., & Nakashima, I. (2023) · Multiple Sclerosis Journal · doi:10.1177/13524585231156736 · Cited by 37
Clinical Profile of Anti-Myelin Oligodendrocyte Glycoprotein Antibody Seropositive Cases of Optic Neuritis
Matsuda, R., Kezuka, T., Umazume, A., Okunuki, Y., Gotô, H., & Tanaka, K. (2015) · Neuro-Ophthalmology · doi:10.3109/01658107.2015.1072726 · Cited by 37
Clinical features and long-term outcome of a group of Japanese children with inflammatory central nervous system disorders and seropositivity to myelin-oligodendrocyte glycoprotein antibodies
Hino‐Fukuyo, N., Haginoya, K., Nakashima, I., Sato, D. K., Takahashi, T., Misu, T., Fujihara, K., Hirose, M., Kakisaka, Y., Uematsu, M., et al. (2015) · Brain and Development · doi:10.1016/j.braindev.2015.02.006 · Cited by 37
Finding NMO: The Evolving Diagnostic Criteria of Neuromyelitis Optica
Bennett, J. L. (2016) · Journal of Neuro-Ophthalmology · doi:10.1097/wno.0000000000000396 · Cited by 42
Subclinical retinal atrophy in the unaffected fellow eyes of multiple sclerosis and neuromyelitis optica
Akaishi, T., Kaneko, K., Himori, N., Takeshita, T., Takahashi, T., Nakazawa, T., Aoki, M., & Nakashima, I. (2017) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2017.10.001 · Cited by 37
Clinical and experimental studies of potentially pathogenic brain-directed autoantibodies: current knowledge and future directions
Varley, J. A., Vincent, A. C., & Irani, S. R. (2014) · Journal of Neurology · doi:10.1007/s00415-014-7600-8 · Cited by 36
Circulating Memory T Follicular Helper Cells in Patients with Neuromyelitis Optica/Neuromyelitis Optica Spectrum Disorders
Fan, X., Jiang, Y., Han, J., Liu, J., Wei, Y., Jiang, X., & Jin, T. (2016) · Mediators of Inflammation · doi:10.1155/2016/3678152 · Cited by 36
Idiopathic aquaporin-4 antibody negative longitudinally extensive transverse myelitis
Hyun, J., Kim, S., Huh, S., Kim, W., Yun, J., Joung, A., Sato, D. K., Fujihara, K., & Kim, H. J. (2014) · Multiple Sclerosis Journal · doi:10.1177/1352458514551454 · Cited by 34
The clinical spectrum associated with myelin oligodendrocyte glycoprotein antibodies (anti-MOG-Ab) in Thai patients
Siritho, S., Sato, D. K., Kaneko, K., Fujihara, K., & Prayoonwiwat, N. (2015) · Multiple Sclerosis Journal · doi:10.1177/1352458515614093 · Cited by 35
Neuromyelitis Optica: Deciphering a Complex Immune-Mediated Astrocytopathy
Bennett, J. L., & Owens, G. P. (2017) · Journal of Neuro-Ophthalmology · doi:10.1097/wno.0000000000000508 · Cited by 36
MOG-IgG-associated disease has a stereotypical clinical course, asymptomatic visual impairment and good treatment response
Pandit, L., Mustafa, S., Nakashima, I., Takahashi, T., & Kaneko, K. (2018) · Multiple Sclerosis Journal - Experimental Translational and Clinical · doi:10.1177/2055217318787829 · Cited by 35
CSF levels of glutamine synthetase and GFAP to explore astrocytic damage in seronegative NMOSD
Kleerekooper, I., Herbert, M. K., Kuiperij, H. B., Sato, D. K., Fujihara, K., Callegaro, D., Marignier, R., Saiz, A., Şenel, M., Tumani, H., et al. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2019-322286 · Cited by 35
Myelin oligodendrocyte glycoprotein-associated disorders are associated with HLA subtypes in a Chinese paediatric-onset cohort
Sun, X., Qiu, W., Wang, J., Wang, S., Wang, Y., Zhong, X., Liu, C., Cui, C., Hong, H. Y., Yang, H., et al. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2019-322115 · Cited by 37
Progression pattern of neurological disability with respect to clinical attacks in anti-MOG antibody-associated disorders
Akaishi, T., Misu, T., Takahashi, T., Takai, Y., Nishiyama, S., Fujimori, J., Ishii, T., Aoki, M., Fujihara, K., & Nakashima, I. (2020) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2020.577467 · Cited by 35
Seronegative Neuromyelitis Optica Spectrum - The challenges on disease definition and pathogenesis
Sato, D. K., Callegaro, D., Lana–Peixoto, M. A., Nakashima, I., & Fujihara, K. (2014) · Arquivos de Neuro-Psiquiatria · doi:10.1590/0004-282x20140032 · Cited by 39
Adaptive Immunity Is the Key to the Understanding of Autoimmune and Paraneoplastic Inflammatory Central Nervous System Disorders
Weissert, R. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00336 · Cited by 37
Telitacicept following plasma exchange in the treatment of subjects with recurrent neuromyelitis optica spectrum disorders: A single‐center, single‐arm, open‐label study
Ding, J., Jiang, X., Cai, Y. C., Pan, S., Deng, Y., Gao, M., Lin, Y. Z., Zhao, N., Wang, Z., Yu, H., et al. (2022) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13904 · Cited by 34
Neuromyelitis optica spectrum disorders: Features of aquaporin-4, myelin oligodendrocyte glycoprotein and double-seronegative-mediated subtypes
Rego, C. A. D., & Collongues, N. (2018) · Revue Neurologique · doi:10.1016/j.neurol.2018.02.084 · Cited by 35
Genetic factors for susceptibility to and manifestations of neuromyelitis optica
Matsushita, T., Masaki, K., Isobe, N., Sato, S., Yamamoto, K., Nakamura, Y., Watanabe, M., Suenaga, T., & Kira, J. (2020) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51147 · Cited by 35
Serum Aquaporin 4-Immunoglobulin G Titer and Neuromyelitis Optica Spectrum Disorder Activity and Severity: A Systematic Review and Meta-Analysis
Liu, J., Tan, G., Li, B., Zhang, J., Gao, Y., Cao, Y., Jia, Z., & Sugimoto, K. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.746959 · Cited by 34
Initial clinical manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine
Fujimori, J., Miyazawa, K., & Nakashima, I. (2021) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2021.577755 · Cited by 33
The MOG antibody non-P42 epitope is predictive of a relapsing course in MOG antibody-associated disease
Liyanage, G., Trewin, B. P., Lopez, J. A., Andersen, J., Tea, F., Merheb, V., Nguyen, K., Lee, F. X. Z., Fabis‐Pedrini, M. J., Zou, A., et al. (2024) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2023-332851 · Cited by 33
Antibody biomarkers in CNS demyelinating diseases – a long and winding road
Berger, T., & Reindl, M. (2015) · European Journal of Neurology · doi:10.1111/ene.12759 · Cited by 33
Neuromyelitis optica spectrum disorders with antibodies to myelin oligodendrocyte glycoprotein or aquaporin-4: Clinical and paraclinical characteristics in Algerian patients
Bouzar, M., Daoudi, S., Hattab, S., Bouzar, A. A., Deiva, K., Wildemann, B., Reindl, M., & Jarius, S. (2017) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2017.08.3254 · Cited by 33
The spectrum of immune-mediated and inflammatory lesions of the brainstem
Law, L. Y., Riminton, S., Nguyen, M., Barnett, M. H., Reddel, S., & Hardy, T. A. (2019) · Neurology · doi:10.1212/wnl.0000000000008015 · Cited by 35
Clinical and immunological differences between MOG associated disease and anti AQP4 antibody-positive neuromyelitis optica spectrum disorders: Blood–brain barrier breakdown and peripheral plasmablasts
Tanaka, S., Hashimoto, B., Izaki, S., Oji, S., Fukaura, H., & Nomura, K. (2020) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2020.102005 · Cited by 33
Comparative study of AQP4-NMOSD, MOGAD and seronegative NMOSD: a single-center Belgian cohort
Dauby, S., Dive, D., Lutteri, L., Andris, C., Hansen, I., Maquet, P., & Lommers, É. (2021) · Acta Neurologica Belgica · doi:10.1007/s13760-021-01712-3 · Cited by 34
Myelin Oligodendrocyte Glycoprotein–Associated Disorders
Longbrake, E. E. (2022) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000001127 · Cited by 36
MOG transmembrane and cytoplasmic domains contain highly stimulatory T-cell epitopes in MS
Varrin‐Doyer, M., Shetty, A., Spencer, C. M., Schulze‐Topphoff, U., Weber, M. S., Bernard, C. C. A., Forsthuber, T. G., Cree, B., Slavin, A., & Zamvil, S. S. (2014) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000000020 · Cited by 33
Plasma Exchange for Neuromyelitis Optica Spectrum Disorders in Chinese Patients and Factors Predictive of Short-term Outcome
Jiao, Y., Cui, L., Zhang, W., Zhang, Y., Wang, W., Zhang, L., Tang, W., & Jiao, J. (2018) · Clinical Therapeutics · doi:10.1016/j.clinthera.2018.03.007 · Cited by 33
The Multiple Roles of B Cells in Multiple Sclerosis and Their Implications in Multiple Sclerosis TherapiesPreprint
Li, R., & Bar‐Or, A. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a029108 · Cited by 32
Pediatric inflammatory brain diseases
Mater, H. V. (2014) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000092 · Cited by 32
Whole brain and grey matter volume of Japanese patients with multiple sclerosis
Akaishi, T., Nakashima, I., Mugikura, S., Aoki, M., & Fujihara, K. (2017) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2017.03.009 · Cited by 32
Pattern Recognition of the Multiple Sclerosis Syndrome
Zabad, R., Stewart, R., & Healey, K. M. (2017) · Brain Sciences · doi:10.3390/brainsci7100138 · Cited by 32
Clinical spectrum of inflammatory central nervous system demyelinating disorders associated with antibodies against myelin oligodendrocyte glycoprotein
Akaishi, T., Sato, D. K., Takahashi, T., & Nakashima, I. (2018) · Neurochemistry International · doi:10.1016/j.neuint.2018.10.016 · Cited by 32
Update on Pediatric Optic Neuritis
Gise, R. A., & Heidary, G. (2020) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-020-1024-x · Cited by 32
High-throughput investigation of molecular and cellular biomarkers in NMOSD
Yandamuri, S. S., Jiang, R., Sharma, A., Cotzomi, E., Zografou, C., Ma, A. K., Alvey, J. S., Cook, L. J., Smith, T. J., Yeaman, M. R., et al. (2020) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000000852 · Cited by 32
CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage
Hyun, J., Kim, Y., Kim, K. H., Kim, S., Olesen, M. N., Asgari, N., Siritho, S., Paul, F., & Kim, H. J. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02450-w · Cited by 34
Neuromyelitis optica spectrum disorders: An update
Pandit, L. (2015) · Annals of Indian Academy of Neurology · doi:10.4103/0972-2327.164816 · Cited by 32
Anti-MOG antibodies with longitudinally extensive transverse myelitis preceded by CLIPPERS
Taïeb, G., & Labauge, P. M. (2015) · Neurology · doi:10.1212/01.wnl.0000472753.44905.98 · Cited by 32
MOG encephalomyelitis: distinct clinical, MRI and CSF features in patients with longitudinal extensive transverse myelitis as first clinical presentation
Loos, J., Pfeuffer, S., Pape, K., Ruck, T., Luessi, F., Spreer, A., Zipp, F., Meuth, S. G., & Bittner, S. (2020) · Journal of Neurology · doi:10.1007/s00415-020-09755-x · Cited by 32
A window into the future? MRI for evaluation of neuromyelitis optica spectrum disorder throughout the disease course
Solomon, J. M., Paul, F., Chien, C., Oh, J., & Rotstein, D. (2021) · Therapeutic Advances in Neurological Disorders · doi:10.1177/17562864211014389 · Cited by 32
Disorders of vision in multiple sclerosis
Dhanapalaratnam, R., Markoulli, M. P., & Krishnan, A. V. (2021) · Clinical and Experimental Optometry · doi:10.1080/08164622.2021.1947745 · Cited by 36
Five-year visual outcomes after optic neuritis in anti-MOG antibody-associated disease
Akaishi, T., Himori, N., Takeshita, T., Misu, T., Takahashi, T., Takai, Y., Nishiyama, S., Fujimori, J., Ishii, T., Aoki, M., et al. (2021) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2021.103222 · Cited by 34
Autoimmune diseases and cancers overlapping with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): A systematic review
Molazadeh, N., Bose, G., Lotan, I., & Levy, M. (2022) · Multiple Sclerosis Journal - Experimental Translational and Clinical · doi:10.1177/20552173221128170 · Cited by 31
Etiologies of acute demyelinating optic neuritis: an observational study of 110 patients
Deschamps, R., Lecler, A., Lamirel, C., Aboab, J., Guéguen, A., Bensa, C., Vignal‐Clermont, C., & Gout, O. (2017) · European Journal of Neurology · doi:10.1111/ene.13315 · Cited by 31
Pediatric inflammatory demyelinating disorders and mimickers: How to differentiate with MRI?
Pereira, F. V., Jarry, V. D. M., de Castro, J. T. D. S., Appenzeller, S., & Reis, F. (2021) · Autoimmunity Reviews · doi:10.1016/j.autrev.2021.102801 · Cited by 33
Therapeutic options in neuromyelitis optica spectrum disorders
Kitley, J., & Palace, J. A. (2016) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2016.1150178 · Cited by 31
Evidence for and against subclinical disease activity and progressive disease in MOG antibody disease and neuromyelitis optica spectrum disorder
Molazadeh, N., Filippatou, A. G., Vasileiou, E. S., Levy, M., & Sotirchos, E. S. (2021) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2021.577702 · Cited by 31
A Comprehensive Review on the Role of Genetic Factors in Neuromyelitis Optica Spectrum Disorder
Ghafouri‐Fard, S., Azimi, T., & Taheri, M. N. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.737673 · Cited by 29
An Adult Case of Anti-Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Multiphasic Acute Disseminated Encephalomyelitis at 33-year Intervals
Numa, S., Kasai, T., Kondo, T., Kushimura, Y., Kimura, A., Takahashi, H., Morita, K., Tanaka, A., Noto, Y., Ohara, T., et al. (2016) · Internal Medicine · doi:10.2169/internalmedicine.55.5727 · Cited by 28
Blood Brain Barrier Permeability Could Be a Biomarker to Predict Severity of Neuromyelitis Optica Spectrum Disorders: A Retrospective Analysis
Wang, Y., Zhu, M., Liu, C., Han, J., Lang, W., Gao, Y., Lu, C., Wang, S., Hou, S., Zheng, N., et al. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00648 · Cited by 28
Elevated intraspinal pressure in traumatic spinal cord injury is a promising therapeutic target
Yang, C., Quan, Z., Wang, Q., Wang, G., He, T., Chen, Z., Li, Q., & Yang, J. (2021) · Neural Regeneration Research · doi:10.4103/1673-5374.332203 · Cited by 28
The Translatability of Multiple Sclerosis Animal Models for Biomarkers Discovery and Their Clinical Use
Birmpili, D., Askar, I. C., Bigaut, K., & Bagnard, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911532 · Cited by 30
A comparison between spinal cord infarction and neuromyelitis optica spectrum disorders: Clinical and MRI studies
Hsu, J., Cheng, M.-Y., Liao, M., Hsu, H., Weng, Y., Chang, K., Chang, H., Kuo, H., Huang, C., Lyu, R., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-43606-8 · Cited by 28
What role should spinal cord MRI take in the future of multiple sclerosis surveillance?
Rocca, M. A., Preziosa, P., & Filippi, M. (2020) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2020.1739524 · Cited by 29
Peripheral blood helper T cell profiles and their clinical relevance in MOG-IgG-associated and AQP4-IgG-associated disorders and MS
Liu, J., Mori, M., Sugimoto, K., Uzawa, A., Masuda, H., Uchida, T., Ohtani, R., & Kuwabara, S. (2019) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2019-321988 · Cited by 26

Authors: Sato, D. K., Callegaro, D., Lana-Peixoto, M. A., Waters, P. J., Jorge, F. M. D. H., Takahashi, T., Nakashima, I., Apostolos-Pereira, S. L., Talim, N., Simm, R. F., Lino, A. M. M., Misu, T., Leite, M. I., Aoki, M., & Fujihara, K.
Affiliations: Universidade Federal de Minas Gerais (BR)
From the Departments of Neurology (D.K.S., T.T., I.N., M.A.) and Multiple Sclerosis Therapeutics (T.M., K.F.), Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Neurology (D.C., F.M.d.H.J., S.L.A.-P., R.F.S., A.M.M.L.), Faculty of Medicine, University of São Paulo, Brazil; CIEM MS Research Center (M.A.L.-P., N.T.), Federal University of Minas Gerais Medical School, Belo Horizonte, Brazil; Neuroimmunology Group (P.J.W., M.I.L.), Nuffield Department of Clinical Neurosciences,...
ORCID: Sato, Douglas Kazutoshi
Callegaro, Dagoberto
Waters, Patrick J.
Takahashi, Toshiyuki
Nakashima, Ichiro
Lino, Angelina Maria Martins
Misu, Tatsuro
Leite, Maria Isabel
Aoki, Masashi
Fujihara, Kazuo
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2014-02-11
Volume: 82
Issue: 6
Pages: 474-481
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.0000000000000101
PMC: PMC3937859
OpenAlex: W2103812851
Cited by: 850
References: 21
Citations by year: 2026: 25 · 2025: 41 · 2024: 45 · 2023: 67 · 2022: 69 · 2021: 94 · 2020: 95 · 2019: 83 · 2018: 76 · 2017: 82 · 2016: 66 · 2015: 66 · 2014: 38
FWCI: 62.41
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
Locations: Neurology (publishedVersion, cc-by-nc-nd)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Japan Society for the Promotion of Science (22229008)
Topics: Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
Health Sciences › Medicine › Clinical Neurology › Peripheral Neuropathies and Disorders
Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Keywords: neuromyelitis optica spectrum disorder, anti-MOG antibodies, aquaporin-4 antibodies, seronegative NMOSD, clinical features, optic neuritis, spinal cord lesions, disease phenotypes, functional recovery, relapse rate
MeSH terms: Adolescent, Adult, Aged, Autoantibodies, Child, Preschool, Female, Humans, Male, Middle Aged, Neuromyelitis Optica, Phenotype, Sex Factors, Aquaporin 4, Young Adult, Myelin-Oligodendrocyte Glycoprotein

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Distinction between MOG antibody-positive and AQP4 antibody-positive NMO spectrum disorders

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks