Cited by 850Multiple Sclerosis Research StudiesPeripheral Neuropathies and DisordersOcular Diseases and Behçet’s Syndrome

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Distinction between MOG antibody-positive and AQP4 antibody-positive NMO spectrum disorders

Open access

Sato, Douglas Kazutoshi, Callegaro, Dagoberto, Lana-Peixoto, Marco Aurelio, Waters, Patrick J., Jorge, Frederico M. de Haidar, Takahashi, Toshiyuki, Nakashima, Ichiro, Apostolos-Pereira, Samira Luisa, Talim, Natalia, Simm, Renata Faria, Lino, Angelina Maria Martins, Misu, Tatsuro, Leite, Maria Isabel, Aoki, Masashi, Fujihara, Kazuo·2014·Neurology

DOI 10.1212/wnl.0000000000000101PMC PMC3937859

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVE: To evaluate clinical features among patients with neuromyelitis optica spectrum disorders (NMOSD) who have myelin oligodendrocyte glycoprotein (MOG) antibodies, aquaporin-4 (AQP4) antibodies, or seronegativity for both antibodies. METHODS: Sera from patients diagnosed with NMOSD in 1 of 3 centers (2 sites in Brazil and 1 site in Japan) were tested for MOG and AQP4 antibodies using cell-based assays with live transfected cells. RESULTS: Among the 215 patients with NMOSD, 7.4% (16/215) were positive for MOG antibodies and 64.7% (139/215) were positive for AQP4 antibodies. No patients were positive for both antibodies. Patients with MOG antibodies represented 21.1% (16/76) of the patients negative for AQP4 antibodies. Compared with patients with AQP4 antibodies or patients who were seronegative, patients with MOG antibodies were more frequently male, had a more restricted phenotype (optic nerve more than spinal cord), more frequently had bilateral simultaneous optic neuritis, more often had a single attack, had spinal cord lesions distributed in the lower portion of the spinal cord, and usually demonstrated better functional recovery after an attack. CONCLUSIONS: Patients with NMOSD with MOG antibodies have distinct clinical features, fewer attacks, and better recovery than patients with AQP4 antibodies or patients seronegative for both antibodies.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1212/wnl.0000000000000101

Cites

21 of 21 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Revised diagnostic criteria for neuromyelitis optica
Wingerchuk, D. M., Lennon, V. A., Pittock, S. J., Lucchinetti, C. F., & Weinshenker, B. G. (2006) · Neurology · doi:10.1212/01.wnl.0000216139.44259.74 · Cited by 2,568
The spectrum of neuromyelitis optica
Wingerchuk, D. M., Lennon, V. A., Lucchinetti, C. F., Pittock, S. J., & Weinshenker, B. G. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70216-8 · Cited by 2,182
The clinical course of neuromyelitis optica (Devic’s syndrome)
Wingerchuk, D. M., Hogancamp, W. E., O’Brien, P. C., & Weinshenker, B. G. (1999) · Neurology · doi:10.1212/wnl.53.5.1107 · Cited by 1,819
Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre
Takahashi, T., Fujihara, K., Nakashima, I., Misu, T., Miyazawa, I., Nakamura, M., Watanabe, S., Shiga, Y., Kanaoka, C., Fujimori, J., et al. (2007) · Brain · doi:10.1093/brain/awm062 · Cited by 633
Neuromyelitis Optica Spectrum Disorders With Aquaporin-4 and Myelin-Oligodendrocyte Glycoprotein Antibodies: A Comparative Study
Kitley, J., Waters, P., Woodhall, M., Leite, M. I., Murchison, A., George, J., Küker, W., Chandratre, S., Vincent, A., & Palace, J. (2014) · JAMA Neurology · doi:10.1001/jamaneurol.2013.5857 · Cited by 597
Serologic diagnosis of NMO: A multicenter comparison of aquaporin-4-IgG assays
Waters, P. J., McKeon, A., Leite, M. I., Rajasekharan, S., Lennon, V. A., Villalobos, A., Palace, J., Mandrekar, J. N., Vincent, A., Bar-Or, A., et al. (2012) · Neurology · doi:10.1212/wnl.0b013e318248dec1 · Cited by 526
Self-citation
Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
Mader, S., Gredler, V., Schanda, K., Rostasy, K. M., Dujmović, I., Pfaller, K., Lutterotti, A., Jarius, S., Pauli, F. D., Kuenz, B., et al. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-184 · Cited by 449
Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype
Kitley, J., Woodhall, M., Waters, P., Leite, M. I., Devenney, E., Craig, J., Palace, J., & Vincent, A. (2012) · Neurology · doi:10.1212/wnl.0b013e31826aac4e · Cited by 445
Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein
O’Connor, K. C., McLaughlin, K. A., Jager, P. L. D., Chitnis, T., Bettelli, E., Xu, C., Robinson, W. H., Cherry, S. V., Bar‐Or, A., Banwell, B., et al. (2007) · Nature Medicine · doi:10.1038/nm1488 · Cited by 419
The spectrum of MOG autoantibody-associated demyelinating diseases
Reindl, M., Pauli, F. D., Rostasy, K. M., & Berger, T. (2013) · Nature Reviews Neurology · doi:10.1038/nrneurol.2013.118 · Cited by 376

Show all 21 references

Sorted by citations

Items 801–848 of 848

Neuromyelitis optica spectrum disorders and beyond: telling a story one hundred years later
Bichuetti, D. B. (2023) · Arquivos de Neuro-Psiquiatria · doi:10.1055/s-0043-1770932
Clinical course features of atypical demyelinating optic neuritis: case series
Sheremet, N. L., Eliseeva, D. D., Bryukhov, V. V., Andreeva, N. A., Zhorzholadze, N. V., Murakhovskaya, Y. K., Kalashnikova, A. K., & Zakharova, M. N. (2023) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2023-1s-35-42
Clinical features and modern diagnostic criteria of the disease associated with myelin oligodendrocyte glycoprotein antibody disease
Belova, A. N., Sheiko, G. Е., Rakhmanova, E. M., & Boyko, A. N. (2023) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro202312311147
Understanding MOG antibody-associated disease in Brazil
Callegaro, D., & Silva, G. D. (2023) · Arquivos de Neuro-Psiquiatria · doi:10.1055/s-0043-1777298
Klinik Nöroloji
Karcı, M. T., Özyurt, E., Ercan, M. B., Kenar, S. G., Demirdöğen, F., Özenç, B., Beton, Ö. E., Türkmen, N., Şen, M., Açıkgöz, M., et al. (2022) · Akademisyen Kitabevi eBooks · doi:10.37609/akya.1350
Evaluation of Steroid Pulse Therapy Responsiveness in Myelin-Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis
Takai, Y., Yamagami, A., Iwasa, M., Inoue, K., Wakakura, M., Takahashi, T., & Tanaka, K. (2024) · Cureus · doi:10.7759/cureus.56673
Double Seronegative Neuromyelitis Optica Spectrum Disorder with Longitudinally Extensive Transverse Myelitis and Optic Neuritis: A Challenging Case Report
Han, G. C., Iqbal, T., & Supramaniam, G. (2024) · Cureus · doi:10.7759/cureus.57044
ANTİ-AQUAPORİN 4 ve ANTİ-MİYELİN OLİGODENTROSİT GLİKOPROTEİN ANTİKOR İLİŞKİLİ NÖROMİYELİTİS OPTİKA SPEKTRUM HASTALIĞI TANISI ALAN OLGULARIN KLİNİK ve RADYOLOJİK ÖZELLİKLERİ
Ünlü, M. D., & Demirci, S. (2023) · Ahi Evran Medical Journal · doi:10.46332/aemj.1303107
Two Cases of Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Immunoglobulin G Double-Positive Optic Neuritis Successfully Treated With Steroid Therapy
Fujii, N., Fukuda, K., Nakajima, I., Mizobuchi, T., Masaoka, M., Takahashi, T., & Yamashiro, K. (2024) · Journal of Neuro-Ophthalmology · doi:10.1097/wno.0000000000002140
Acute-Onset Blindness in a Patient Diagnosed With Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOG-AD): A Case Report
Gyabaah, F., Petersen, C., Bateman, E. M., & Deoker, A. (2024) · Cureus · doi:10.7759/cureus.61767
A Case of NMOSD with Double Seropositive for AQP-4 and MOG Antibodies
Jeon, C., & Kim, Y. H. (2024) · Korean Journal of Neuromuscular Disorders · doi:10.46518/kjnmd.2024.16.1.14
Neuromyelitis optica spectrum disorder and other central nervous system inflammatory diseases
Thakolwiboon, S., & Flanagan, E. P. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-23947-2.00019-9
Epidemiology of optic disc edema in 2021/2022: Results from a cohort of 197 patients
Attia, R., Stolowy, N., Fitoussi, R., Mairot, K., & David, T. (2024) · Revue Neurologique · doi:10.1016/j.neurol.2024.09.010
Etiology and Clinical Profile of Pediatric Acquired Demyelination Syndromes of the Central Nervous System: An Ambispective Longitudinal Study from South India
Sugumar, K., Chidambaram, A. C., & Ramamoorthy, J. G. (2024) · Indian journal of clinical medicine · doi:10.1177/26339447241297011
Preliminary observations in cortical excitability changes using transcranial magnetic stimulation (TMS), it’s correlation with diffusion tensor imaging (DTI) in subjects with neuromyelitis optica spectrum disorder (NMOSD)
Shaik, R. S., Ganaraja, V. H., Bhattacharya, A., Kumar, M., Nitish, L. K., Bhat, M. D., Pal, P. K., Mahadevan, A., & Netravathi, M. (2025) · Acta Neurologica Belgica · doi:10.1007/s13760-025-02718-x
A Stitch in Time Saves Nine: Optic Neuritis in a Keratoconus Patient
Monga, S. (2024) · Springer eBooks · doi:10.1007/978-981-96-0286-5_52
MR Imaging of Autoimmune Inflammatory and Demyelinating Myelopathies
Rovira, À., de Gordoa, E. S., & Auger, C. (2025) · Magnetic Resonance Imaging Clinics of North America · doi:10.1016/j.mric.2025.01.004
Herpes Zoster Myelitis Mimicking Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Disease: A Case Report
Oyama, T., Omichi, K., Iwade, N., & Nakanishi, H. (2025) · Cureus · doi:10.7759/cureus.81782
Diagnostic Dilemma in the Management of a Cervical Spinal Cord Lesion: A Case Report of Neuromyelitis Optica Spectrum Disorder
Azode, K. M., Balogun, S. A., Komolafe, M. A., Olasode, B. J., & Komolafe, E. (2025) · International Journal of Neurosurgery · doi:10.11648/j.ijn.20250901.14
Disrupted static and dynamic Large-scale brain functional network connectivity in the differentiation of myelin oligodendrocyte glycoprotein Antibody-Seropositive from seronegative optic neuritis
Wang, W., Liu, X., Sha, Y., Wang, X., & Lü, P. (2025) · Neuroradiology · doi:10.1007/s00234-025-03643-9
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: A Diverse Demyelinating Entity in Pediatric Patients
Ibrahim, B. A., Abdullah, W. H., Hussein, M. A., & Abdulraheem, R. S. (2025) · Al-Rafidain Journal of Medical Sciences · doi:10.54133/ajms.v9i2.2297
Characterizing double seronegative neuromyelitis optica spectrum disorder: A distinct subgroup or part of the continuum?
Piedrabuena, M. A., Marrodán, M., Zárate, M. A., Fiol, M. P., Ysrraelit, M. C., & Correale, J. D. (2025) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2025.578822 · Cited by 3
SPHERES: innovative registry addressing the new era of neuromyelitis optica spectrum disorders (NMOSD) therapy
Bennett, J. L., Middaugh, N., Yeaman, M. R., Smith, T. J., Behne, M. K., Crabtree, M. M., McLean, R. R., Pappas, D. A., & Levy, M. (2025) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2025.106940
Additional file 1 of CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage
Hyun, J.-W., Kim, Y., Kim, K. H., Kim, S.-H., Olesen, M. N., Asgari, N., Siritho, S., Paul, F., & Kim, H. J. (2022) · Figshare · doi:10.6084/m9.figshare.19589256
Additional file 1 of Anti-NMDA receptor encephalitis and MOG-associated demyelination – a case report with long-term follow-up and a systematic review
Berek, K., Grams, A., Uprimny, C., Prieschl, M., Ramberger, M., Unterberger, I., Deisenhammer, F., Reindl, M., & Hegen, H. (2022) · Figshare · doi:10.6084/m9.figshare.21582305
Additional file 2 of Anti-NMDA receptor encephalitis and MOG-associated demyelination – a case report with long-term follow-up and a systematic review
Berek, K., Grams, A., Uprimny, C., Prieschl, M., Ramberger, M., Unterberger, I., Deisenhammer, F., Reindl, M., & Hegen, H. (2022) · Figshare · doi:10.6084/m9.figshare.21582308
Non-neoplastic Spinal Cord Diseases
Lee, G. Y. (2025) · Springer eBooks · doi:10.1007/978-981-95-1386-4_12
Double Anti‐NMO and Anti‐MOG Positivity in a Patient With Metastatic Renal Carcinoma: First Reported Case
García, M. F., Belenguer, A., Madera, S. B., Andrés, H. B., Beclua, A. M., Gimeno, A. R., & Popova, L. (2026) · Case Reports in Neurological Medicine · doi:10.1155/crnm/6191174
Névrite optique atypique avec double positivité des anticorps anti-aquaporine 4 et des anticorps anti-myelin oligodendrocyte glycoprotein
Nouira, C., Lobjois, Q., Mehdoui, H., Cabre, P., & Merle, H. (2026) · Journal Français d Ophtalmologie · doi:10.1016/j.jfo.2026.104785
Neuromyelitis optica – a cause for longitudinally extensive transverse myelitis: a rare case report from Nepal and literature review
Sah, U. R., Tripathi, A., Shah, S., Poudel, S., Bhardwaj, A., Jha, A., Mishra, A., Yadav, A. K., & Nishad, S. R. (2025) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000004622
Dual AQP4-IgG and MOG-IgG seropositivity in a 75-year-old woman: Challenging the mutual exclusivity paradigm in NMOSD
Cai, K., Huang, Z., Gao, Y., & Zhan, J. (2026) · Neuroimmunology Reports · doi:10.1016/j.nerep.2026.100278
Relapse risk factors in double seronegative neuromyelitis optica spectrum disorder: Insights from a multicenter study
Vallejos, G. B., Mikami, T., Mahler, J. V., Sezen, A., Silva, G. D., Solti, M., Apóstolos‐Pereira, S. L., Callegaro, D., Matiello, M., Altintas, A., et al. (2026) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2026.107123
Relapse and Neurological Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease: A Retrospective Secondary Analysis of a Japanese Nationwide Epidemiologic Survey
Nakamura, M., Fujimori, J., Uzawa, A., Kuwabara, S., & Nakashima, I. (2026) · Clinical and Experimental Neuroimmunology · doi:10.1111/cen3.70059
Novel B-Cell targeting therapy with subcutaneous ofatumumab in AQP4-IgG-seronegative Neuromyelitis Optica Spectrum Disorders: efficacy and personalized dosing
Cao, X., Qin, D., Wang, B., Wang, C., & Guo, S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1760491
A real-world study on the long-term efficacy of rituximab in relapsing myelin oligodendrocyte glycoprotein antibody-associated disease
Yu, C., Chen, X., Jiang, W., Sun, H., Gao, S., Huang, D., Wu, L., & Yu, S. (2026) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2026.107154
Diagnosis and antibody status awareness in neuromyelitis optica spectrum disorder and MOG-associated disease: A cross-sectional study
Apóstolos‐Pereira, S. L., Terrim, S., de Araujo, R. S., Nogueira, A. B. S., Tieppo, E. M. D. S., Faria, G. A. S., Silva, P. B. R., Filho, F. V. M., Santillan, T. I. V., Rosalem, R. A., et al. (2026) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2026.107174
L'épendyme : une nouvelle cible dans les maladies neuroinflammatoires ?
Bigotte, M. (2022) · doi:10.70675/11c4c2a7zdc82z4184z9d68zcf87d57df47f
MOG Antibody Status Shapes Divergent Clinical Profiles And Therapeutic Responses In Chronic Relapsing Inflammatory Optic NeuropathyPreprint
Graure, M., Nierobisch, N., Vere-Tyndall, A. D., Pakeerathan, T., Ayzenberg, I., Gernert, J. A., Havla, J. B., Ringelstein, M., Aktaş, O., Tkachenko, D. P., et al. (2026) · medRxiv · doi:10.64898/2026.04.20.26351249
Integrated Blood Inflammatory Ratios and Cerebrospinal Fluid Blood‒Brain Barrier Dysfunction Predict Relapse Risk in Neuromyelitis Optica Spectrum Disorder
Zheng, X., Shi, J., Yin, H., Song, H., Zhai, Q., Si, C., Chen, J., Li, P., Zhang, L., Li, Y., et al. (2026) · Brain and Behavior · doi:10.1002/brb3.71481
Clinical risk factors for recurrence in adult-onset myelin oligodendrocyte glycoprotein antibody-associated optic neuritis
Cao, S., Wu, T., Pan, C., Wei, S., Zhou, H., & Liu, Y. (2026) · BMC Ophthalmology · doi:10.1186/s12886-026-05097-w
Double-Negative Neuromyelitis Optica Spectrum Disorder
Malvaso, A., Bovis, F., Greco, G., Morandi, C., Businaro, P., Masciocchi, S., Marchioni, E., Franciotta, D. M., Sormani, M. P., & Gastaldi, M. (2026) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000200613
Biomarkers for myelin oligodendrocyte glycoprotein-associated disease: recent advances and future
Zheng, Q., Wen, M., Zheng, X., Wen, L., Cheng, R., Gao, Y., Yuan, C., & Shang, P. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1807565
NMOSD and MOGAD in Latin America: A consensus-informed regional perspective
Boldrini, V. D. O., Samadzadeh, S., Contentti, E. C., Pimentel, V., Szejko, N., Ciampi, E., Palace, J. A., Paul, F., Becker, J., & Damasceno, A. (2026) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2026.107438
Neuromyelitis optica spectrum disorder overlapping with Sjögren’s disease: immunopathological links and therapeutic implications
Xu, W., Xing, H., & Hou, L. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1931729
Full-Field Electroretinography Reveals Distinct Functional Retinal Profiles in AQP4-IgG-Positive NMOSD and MOGAD Optic Neuritis Despite Similar Structural OCT FindingsPreprint
Monteiro, M. L., Pereira, C. R., Andrade, T., Apóstolos‐Pereira, S. L., Gomes, A. B. A. G. R., Mello, L. G. M., Oyamada, M. K., Zacharias, L. C., Callegaro, D., & Pröbstel, A. (2026) · Research Square · doi:10.21203/rs.3.rs-10562037/v1
Identification of risk factors for relapse at initial onset in myelin oligodendrocyte glycoprotein antibody–associated optic neuritis using ophthalmic findings
Yamaguchi, C., Himori, N., Kiyota, N., Misu, T., Kaneko, K., Takagi, A., Suzuki, K., Matsumoto, Y., Ninomiya, T., Tsuda, S., et al. (2026) · Japanese Journal of Ophthalmology · doi:10.1007/s10384-026-01415-3
Elderly-Onset Brainstem Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: A Glioma Mimic
Apparasu, N., Surendranath, A., Kengen, A., Muddasani, A. R., & Pingali, Y. K. (2026) · Cureus · doi:10.7759/cureus.117898
MOG Antibody Status Is Associated With Distinct Clinical Profiles and Treatment Responses in Chronic Relapsing Inflammatory Optic Neuropathy
Graure, M., Nierobisch, N., Vere-Tyndall, A. D., Pakeerathan, T., Ayzenberg, I., Gernert, J. A., Havla, J. B., Ringelstein, M., Aktaş, O., Tkachenko, D. P., et al. (2026) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000200668

Authors: Sato, D. K., Callegaro, D., Lana-Peixoto, M. A., Waters, P. J., Jorge, F. M. D. H., Takahashi, T., Nakashima, I., Apostolos-Pereira, S. L., Talim, N., Simm, R. F., Lino, A. M. M., Misu, T., Leite, M. I., Aoki, M., & Fujihara, K.
Affiliations: Universidade Federal de Minas Gerais (BR)
From the Departments of Neurology (D.K.S., T.T., I.N., M.A.) and Multiple Sclerosis Therapeutics (T.M., K.F.), Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Neurology (D.C., F.M.d.H.J., S.L.A.-P., R.F.S., A.M.M.L.), Faculty of Medicine, University of São Paulo, Brazil; CIEM MS Research Center (M.A.L.-P., N.T.), Federal University of Minas Gerais Medical School, Belo Horizonte, Brazil; Neuroimmunology Group (P.J.W., M.I.L.), Nuffield Department of Clinical Neurosciences,...
ORCID: Sato, Douglas Kazutoshi
Callegaro, Dagoberto
Waters, Patrick J.
Takahashi, Toshiyuki
Nakashima, Ichiro
Lino, Angelina Maria Martins
Misu, Tatsuro
Leite, Maria Isabel
Aoki, Masashi
Fujihara, Kazuo
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2014-02-11
Volume: 82
Issue: 6
Pages: 474-481
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.0000000000000101
PMC: PMC3937859
OpenAlex: W2103812851
Cited by: 850
References: 21
Citations by year: 2026: 25 · 2025: 41 · 2024: 45 · 2023: 67 · 2022: 69 · 2021: 94 · 2020: 95 · 2019: 83 · 2018: 76 · 2017: 82 · 2016: 66 · 2015: 66 · 2014: 38
FWCI: 62.41
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
Locations: Neurology (publishedVersion, cc-by-nc-nd)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Japan Society for the Promotion of Science (22229008)
Topics: Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
Health Sciences › Medicine › Clinical Neurology › Peripheral Neuropathies and Disorders
Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Keywords: neuromyelitis optica spectrum disorder, anti-MOG antibodies, aquaporin-4 antibodies, seronegative NMOSD, clinical features, optic neuritis, spinal cord lesions, disease phenotypes, functional recovery, relapse rate
MeSH terms: Adolescent, Adult, Aged, Autoantibodies, Child, Preschool, Female, Humans, Male, Middle Aged, Neuromyelitis Optica, Phenotype, Sex Factors, Aquaporin 4, Young Adult, Myelin-Oligodendrocyte Glycoprotein

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Distinction between MOG antibody-positive and AQP4 antibody-positive NMO spectrum disorders

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks