The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Motor speech signature of behavioral variant frontotemporal dementia: Refining the phenotype
Open accessAbstract
OBJECTIVE: To provide a comprehensive description of motor speech function in behavioral variant frontotemporal dementia (bvFTD). METHODS: Forty-eight individuals (24 bvFTD and 24 age- and sex-matched healthy controls) provided speech samples. These varied in complexity and thus cognitive demand. Their language was assessed using the Progressive Aphasia Language Scale and verbal fluency tasks. Speech was analyzed perceptually to describe the nature of deficits and acoustically to quantify differences between patients with bvFTD and healthy controls. Cortical thickness and subcortical volume derived from MRI scans were correlated with speech outcomes in patients with bvFTD. RESULTS: Speech of affected individuals was significantly different from that of healthy controls. The speech signature of patients with bvFTD is characterized by a reduced rate (75%) and accuracy (65%) on alternating syllable production tasks, and prosodic deficits including reduced speech rate (45%), prolonged intervals (54%), and use of short phrases (41%). Groups differed on acoustic measures derived from the reading, unprepared monologue, and diadochokinetic tasks but not the days of the week or sustained vowel tasks. Variability of silence length was associated with cortical thickness of the inferior frontal gyrus and insula and speech rate with the precentral gyrus. CONCLUSIONS: One in 8 patients presented with moderate speech timing deficits with a further two-thirds rated as mild or subclinical. Subtle but measurable deficits in prosody are common in bvFTD and should be considered during disease management. Language function correlated with speech timing measures derived from the unprepared monologue only.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,603
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
Fischl, B. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.01.021 · Cited by 9,526
Fischl, B., Salat, D. H., Busa, E., Albert, M., Dieterich, M., Haselgrove, C., van der Kouwe, A., Killiany, R., Kennedy, D., Klaveness, S., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00569-x · Cited by 8,610
Saliency, switching, attention and control: a network model of insula function
Menon, V., & Uddin, L. Q. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0262-0 · Cited by 5,592
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., van Swieten, J. C., Seelaar, H., Dopper, E. G. P., Onyike, C. U., et al. (2011) · Brain · doi:10.1093/brain/awr179 · Cited by 5,221
Classification of primary progressive aphasia and its variants
Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. F., Ogar, J. M., Rohrer, J. D., Black, S., Boeve, B. F., et al. (2011) · Neurology · doi:10.1212/wnl.0b013e31821103e6 · Cited by 5,141
Where do you know what you know? The representation of semantic knowledge in the human brain
Patterson, K., Nestor, P. J., & Rogers, T. T. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2277 · Cited by 2,706
The anatomy of language: a review of 100 fMRI studies published in 2009
Price, C. J. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05444.x · Cited by 1,387
The prevalence of frontotemporal dementia
Ratnavalli, E., Brayne, C., Dawson, K. E., & Hodges, J. R. (2002) · Neurology · doi:10.1212/wnl.58.11.1615 · Cited by 1,182
Cited by
Sorted by citations
Magee, M., Lewis, C. C., Noffs, G., Reece, H., Chan, J. C. S., Zaga, C. J., Paynter, C., Birchall, O., Rojas, S., Ediriweera, A., et al. (2020) · The Journal of the Acoustical Society of America · doi:10.1121/10.0002873 · Cited by 205
Self-citationWhat speech can tell us: A systematic review of dysarthria characteristics in Multiple Sclerosis
Noffs, G., Perera, T., Kolbe, S., Shanahan, C. J., Boonstra, F. M. C., Evans, A. H., Butzkueven, H., van der Walt, A., & Vogel, A. P. (2018) · Autoimmunity Reviews · doi:10.1016/j.autrev.2018.06.010 · Cited by 127
Self-citationSpeech and language impairments in behavioral variant frontotemporal dementia: A systematic review
Geraudie, A., Battista, P., García, A. M., Allen, I. E., Miller, Z. A., Gorno-Tempini, M. L., & Montembeault, M. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.10.015 · Cited by 80
Kent, R. D., Kim, Y., & Chen, L.-M. (2021) · Journal of Speech Language and Hearing Research · doi:10.1044/2021_jslhr-21-00396 · Cited by 77
Chan, J. C. S., Stout, J. C., & Vogel, A. P. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.08.009 · Cited by 54
Self-citationTamplin, J., Morris, M. E., Marigliani, C., Baker, F. A., Noffs, G., & Vogel, A. P. (2020) · Journal of Parkinson s Disease · doi:10.3233/jpd-191838 · Cited by 51
Self-citationTowards interpretable speech biomarkers: exploring MFCCs
Tracey, B., Volfson, D., Glass, J., Haulcy, R., Kostrzebski, M., Adams, J., Kangarloo, T., Brodtmann, A., Dorsey, E. R., & Vogel, A. (2023) · Scientific Reports · doi:10.1038/s41598-023-49352-2 · Cited by 46
Self-citationConsensus Paper: Neurophysiological Assessments of Ataxias in Daily Practice
Ilg, W., Branscheidt, M., Butala, A., Celnik, P. A., de Paola, L., Horak, F. B., Schöls, L. J., Teive, H. A. G., Vogel, A. P., Zee, D. S., et al. (2018) · The Cerebellum · doi:10.1007/s12311-018-0937-2 · Cited by 41
Self-citationSpeech metrics, general disability, brain imaging and quality of life in multiple sclerosis
Noffs, G., Boonstra, F. M. C., Perera, T., Butzkueven, H., Kolbe, S., Maldonado, F., Lizama, L. E. C., Galea, M. P., Stankovich, J. M., Evans, A. H., et al. (2020) · European Journal of Neurology · doi:10.1111/ene.14523 · Cited by 38
Self-citationIvanova, O., Martínez‐Nicolás, I., & Meilán, J. J. G. (2024) · International Journal of Language & Communication Disorders · doi:10.1111/1460-6984.12888 · Cited by 38
Ivanova, O., Meilán, J. J. G., Martínez‐Sánchez, F., Martínez‐Nicolás, I., Llorente, T. E., & Carcavilla-González, N. (2021) · Computer Speech & Language · doi:10.1016/j.csl.2021.101341 · Cited by 35
Vogel, A. P., Rommel, N., Oettinger, A., Stoll, L. H., Kraus, E.-M., Gagnon, C., Horger, M. S., Krumm, P., Timmann, D., Storey, E., et al. (2018) · Journal of Neurology · doi:10.1007/s00415-018-8950-4 · Cited by 31
Self-citationMacoir, J., Tremblay, P., & Hudon, C. (2022) · Behavioral Sciences · doi:10.3390/bs12120491 · Cited by 19
Language impairment in the genetic forms of behavioural variant frontotemporal dementia
Samra, K., MacDougall, A. M., Bouzigues, A., Bocchetta, M., Cash, D. M., Greaves, C. V., Convery, R. S., Swieten, J. C. V., Seelaar, H., Jiskoot, L. C., et al. (2022) · Journal of Neurology · doi:10.1007/s00415-022-11512-1 · Cited by 16
Clinical relevance of cortical network dynamics in early primary progressive MS
Tur, C., Kanber, B., Eshaghi, A., Altmann, D. R., Khaleeli, Z., Prados, F., Sebastien Ourselin, A., Thompson, A. J., Wheeler‐Kingshott, C. A. M. G., Toosy, A., et al. (2019) · Multiple Sclerosis Journal · doi:10.1177/1352458519831400 · Cited by 16
Rowe, H. P., Gochyyev, P., Lammert, A. C., Lowit, A., Spencer, K. A., Dickerson, B. C., Berry, J. D., & Green, J. R. (2022) · Journal of Neural Transmission · doi:10.1007/s00702-022-02550-0 · Cited by 15
A Tutorial Review on Clinical Acoustic Markers in Speech Science
Schultz, B. G., & Vogel, A. P. (2022) · Journal of Speech Language and Hearing Research · doi:10.1044/2022_jslhr-21-00647 · Cited by 13
Self-citationVogel, A. P., Sobańska, A., Gupta, A. S., Vasco, G., Grobe‐Einsler, M., Summa, S., & Borel, S. (2023) · The Cerebellum · doi:10.1007/s12311-023-01623-4 · Cited by 12
Self-citationPerceptual and Acoustic Analysis of Speech in Spinocerebellar ataxia Type 1
van Prooije, T. H., Knuijt, S., Oostveen, J., Kapteijns, K. C. J., Vogel, A. P., & van de Warrenburg, B. P. C. (2023) · The Cerebellum · doi:10.1007/s12311-023-01513-9 · Cited by 14
Self-citationMontembeault, M., Miller, Z., Geraudie, A., Pressman, P., Slegers, A., Millanski, C., Licata, A. E., Ratnasiri, B. M., Mandelli, M. L., Henry, M. L., et al. (2023) · Brain Communications · doi:10.1093/braincomms/fcad077 · Cited by 11
Neurodegenerative Disorders of Speech and Language: Non-language-dominant Diseases
García, A. M., DeLeon, J., & Tee, B. L. (2022) · Encyclopedia of Behavioral Neuroscience, 2nd edition · doi:10.1016/b978-0-12-819641-0.00042-6 · Cited by 10
Frontotemporal Dementia Differential Diagnosis in Clinical Practice
Krishnadas, N., Chew, M., Sutherland, A., Christensen, M., Rogers, K., Kyndt, C., Islam, F., Darby, D., & Brodtmann, A. G. (2024) · Neurology Clinical Practice · doi:10.1212/cpj.0000000000200360 · Cited by 12
Self-citationInterpersonal prosodic correlation in frontotemporal dementia
Pressman, P., Ross, E. D., Cohen, K. B., Chen, K., Miller, B. L., Hunter, L., Gorno‐Tempini, M. L., & LEVENSON, R. W. (2019) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.50816 · Cited by 9
Calà, F., Frassineti, L., Cantarella, G., Buccichini, G., Battilocchi, L., Manfredi, C., & Lanatà, A. (2025) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2025.107530 · Cited by 11
Adults with a history of recreational cannabis use have altered speech production
Vogel, A. P., Pearson-Dennett, V., Magee, M., Wilcox, R. A., Esterman, A., Thewlis, D., White, J. M., & Todd, G. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.108963 · Cited by 8
Self-citationDeveloping digital health technologies for frontotemporal degeneration
Nevler, N., Niehoff, D., Gleixner, A. M., Dodge, S., Vogel, A. P., Hill, D. L., Ducharme, S., Staffaroni, A. M., Yunusova, Y., Au, R., et al. (2025) · Alzheimer's & Dementia · doi:10.1002/alz.70082 · Cited by 7
Self-citationLanguage in behavioral variant frontotemporal dementia: Another stone to be turned in Latin America
Geraudie, A., Díaz Rivera, M., Montembeault, M., & García, A. M. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.702770 · Cited by 7
Haj, M. E., Kapogiannis, D., & Boutoleau‐Bretonnière, C. (2023) · Journal of Neurolinguistics · doi:10.1016/j.jneuroling.2023.101164 · Cited by 8
Exploring Emotion and Emotional Variability as DigitalBiomarkers in Frontotemporal Dementia Speech
Gong, Y., Parllaku, F., Placek, K., Vilela, M., Harel, B. T., Simen, A. A., Subirana, B., Brodtmann, A. G., Vogel, A. P., & Tracey, B. (2024) · IEEE Access · doi:10.1109/access.2024.3402999 · Cited by 6
Self-citationMeade, G. F., Machulda, M. M., Clark, H. M., Duffy, J. R., Botha, H., Whitwell, J. L., Josephs, K. A., & Utianski, R. L. (2024) · American Journal of Speech-Language Pathology · doi:10.1044/2024_ajslp-24-00013 · Cited by 7
Utianski, R. L., Botha, H., Duffy, J. R., Clark, H. M., Martin, P. R., Butts, A. M., Machulda, M. M., Whitwell, J. L., & Josephs, K. A. (2018) · The Journal of the Acoustical Society of America · doi:10.1121/1.5082210 · Cited by 6
Speech Analysis in Preclinical Identification of Alzheimer’s Disease
Ivanova, O., & Meilán, J. J. G. (2022) · Lecture notes in computer science · doi:10.1007/978-3-031-06242-1_36 · Cited by 5
Cognitive and Neuroanatomic Accounts of Referential Communication in Focal Dementia
Healey, M. L., Spotorno, N., Olm, C. A., Irwin, D. J., & Grossman, M. (2019) · eNeuro · doi:10.1523/eneuro.0488-18.2019 · Cited by 5
Plug-and-Play Microphones for Recording Speech and Voice with Smart Devices
Noffs, G., Cobler-Lichter, M., Perera, T., Kolbe, S. C., Butzkueven, H., Boonstra, F. M. C., van der Walt, A., & Vogel, A. P. (2024) · Folia Phoniatrica et Logopaedica · doi:10.1159/000535152 · Cited by 5
Self-citationVogel, A. P., Maruff, P. T., Reece, H., Carter, H., Tai, G., Schultz, B. G., Corben, L. A., Delatycki, M. B., & Tsanas, A. (2023) · medRxiv · doi:10.1101/2023.03.28.23287878 · Cited by 5
Self-citationBaqué, L., Ayuso, M. J. M., & Santos‐Santos, M. (2022) · Revista de Neurología · doi:10.33588/rn.7402.2021197 · Cited by 5
Linking motor speech function and dementia
Poole, M. L., & Vogel, A. P. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815868-5.00042-6 · Cited by 5
Self-citationHaulcy, R., Placek, K., Tracey, B., Vogel, A. P., & Glass, J. R. (2022) · IEEE International Conference on Acoustics Speech and Signal Processing · doi:10.1109/icassp43922.2022.9746627 · Cited by 3
Self-citationGiffard, J., Li, R., Roccati, E., Vogel, A. P., Bindoff, A. D., Goldberg, L. R., Bai, Q., & Alty, J. (2025) · GeroScience · doi:10.1007/s11357-025-01739-x · Cited by 2
Self-citationElvira‐García, W., & Aguiar, V. M. (2020) · Loquens · doi:10.3989/loquens.2020.068 · Cited by 2
18 Diagnosis and Differential Diagnosis of Acquired Motor Speech Disorders (Dysarthria, Dyspraxia)
Aiello, E. N., Alfonsi, E., Balaguer, M., Biondi, S. M., Cappa, S., Cosentino, G., Fresia, M., Kasprian, G. J., Maassen, B., Mecca, D., et al. (2025) · European manual of medicine · doi:10.1007/978-3-031-48091-1_3 · Cited by 2
Self-citationAutomated and objective analysis of speech in premanifest and early-stage Huntington’s diseasePreprint
Vogel, A. P., Chan, C. S. J., Stuart, G. W., Maruff, P. T., Lie, Y., & Stout, J. C. (2022) · medRxiv · doi:10.1101/2022.10.27.22281625 · Cited by 1
Self-citationSiddiqui, A., Snyder, P. J., Alber, J., Kathiresan, T., & Vogel, A. P. (2025) · medRxiv · doi:10.64898/2025.12.04.25341021 · Cited by 1
Self-citationDysfluency in primary progressive aphasia: Temporal speech parameters
Baqué, L., & Ayuso, M. J. M. (2024) · Clinical Linguistics & Phonetics · doi:10.1080/02699206.2024.2378345 · Cited by 1
What can speech tell us about pain?
Gonzales, A., Yao, K., Vogel, A. P., & Egorova, N. (2025) · PAIN Reports · doi:10.1097/pr9.0000000000001293
Self-citationIto, Y., Ohdake, R., Kato, S., Masuda, M., Suzuki, M., Watanabe, H., Sakuma, T., Ishibashi, K., Ogura, A., Hara, K., et al. (2025) · Research Square · doi:10.21203/rs.3.rs-7221442/v1
Automated Online Speech Analytics Reveal Language and Affective Changes in Parkinson’s DiseasePreprint
Cao, F., McAloney, K., Kumar, K. R., Martin, N. G., Gharahkhani, P., Vogel, A. P., & Rentería, M. E. (2025) · medRxiv · doi:10.1101/2025.11.09.25339865
Self-citationJiskoot, L. C., Aro, O. A., de Boer, L., Poos, J. M., Houwer, J. F. H. D., Swartenbroekx, T., Dopper, E. G. P., van den Berg, E., & Seelaar, H. (2026) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.70346
Kathiresan, T., Ling, Y.-T., Gasparini, L., Piccolo, S. E., Tjiandra, C., Elhammamy, H., Brodtmann, A., & Vogel, A. P. (2026) · Research Square · doi:10.21203/rs.3.rs-9892520/v1
Self-citation
Metadata
- Authors
- Vogel, A. P., Poole, M. L., Pemberton, H., Caverlé, M. W. J., Boonstra, F. M. C., Low, E., Darby, D., & Brodtmann, A.
- Affiliations
- Box Hill Hospital (AU)
- ORCID
- Venue
- Neurology
- Published
- 2017-08-22
- Volume
- 89
- Issue
- 8
- Pages
- 837-844
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2738539667
- Cited by
- 49
- References
- 41
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 4 · 2023: 8 · 2022: 8 · 2021: 5 · 2020: 6 · 2019: 4 · 2018: 4
- FWCI
- 3.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Health Sciences › Health Professions › Speech and Hearing › Voice and Speech Disorders
- Keywords
- behavioral variant frontotemporal dementia, motor speech, prosody, speech rate, speech acoustics, cortical thickness, inferior frontal gyrus, insula, precentral gyrus, speech fluency, language functions
- MeSH terms
- Cerebral Cortex, Female, Humans, Lactose Tolerance Test, Magnetic Resonance Imaging, Male, Middle Aged, Motor Skills, Organ Size, Phenotype, Speech, Speech Production Measurement, Frontotemporal Dementia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
