The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Traumatic brain injury may not increase the risk of Alzheimer disease
Open accessAbstract
Traumatic brain injury (TBI) commonly occurs in civilian and military populations. Some epidemiologic studies previously have associated TBI with an increased risk of Alzheimer disease (AD). Recent clinicopathologic and biomarker studies have failed to confirm the relationship of TBI to the development of AD dementia or pathologic changes, and suggest that other neurodegenerative processes might be linked to TBI. Additional studies are required to determine the long-term consequences of TBI.
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“A longstanding concern with many clinical studies is reliance on self-report and use of diagnostic verbiage in medical records to identify a correlation between TBI and post-injury development of AD (32).”
From The Inflammatory Continuum of Traumatic Brain Injury and Alzheimer’s Disease (2018) · cites this paper as [32]
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Cites
Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy
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Cognitive Sequelae of Traumatic Brain Injury
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Risk Factors and Preventive Interventions for Alzheimer Disease
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Barnes, D. E., Byers, A. L., Gardner, R. C., Seal, K. H., Boscardin, W. J., & Yaffe, K. (2018) · JAMA Neurology · doi:10.1001/jamaneurol.2018.0815 · Cited by 398
Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link
Ramos‐Cejudo, J., Wısnıewskı, T., Marmar, C. R., Zetterberg, H., Blennow, K., de Leon, M. J., & Fossati, S. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.01.021 · Cited by 406
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Microglia in Alzheimer's Disease: Risk Factors and Inflammation
Katsumoto, A., Takeuchi, H., Takahashi, K., & Tanaka, F. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00978 · Cited by 140
The Inflammatory Continuum of Traumatic Brain Injury and Alzheimer’s Disease
Kokiko-Cochran, O. N., & Godbout, J. P. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00672 · Cited by 128
Metadata
- Authors
- Weiner, M. W., Crane, P. K., Montine, T. J., Bennett, D. A., & Veitch, D. P.
- Affiliations
- Rush University Medical Center (US)
- Corresponding author
- Weiner, Michael W.
- Venue
- Neurology
- Published
- 2017-10-31
- Volume
- 89
- Issue
- 18
- Pages
- 1923-1925
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- PMC
- PMC5664292
- OpenAlex
- W2763169728
- Cited by
- 71
- References
- 19
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 6 · 2023: 6 · 2022: 9 · 2021: 14 · 2020: 9 · 2019: 14 · 2018: 8 · 2017: 1
- FWCI
- 6.86
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- Neurology (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion, cc-by-nc-nd)
- Funders
- U.S. Department of Defense
- Alzheimer's Disease Neuroimaging Initiative
- National Institute on Aging (R01AG017917, R01AG015819, RF1AG015819)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Keywords
- traumatic brain injury, Alzheimer's disease, dementia risk, neurodegeneration, biomarkers, clinicopathological correlation, military personnel, civilian trauma
- MeSH terms
- Brain Injuries, Traumatic, Alzheimer Disease, Humans, Risk Factors
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- CoChat. (2026). Citation check: Traumatic brain injury may not increase the risk of Alzheimer disease. https://app.cochat.ai/papers/10.1212/wnl.0000000000004608
- The paper
- Weiner, M. W., Crane, P. K., Montine, T. J., Bennett, D. A., & Veitch, D. P. (2017). Traumatic brain injury may not increase the risk of Alzheimer disease. Neurology. https://doi.org/10.1212/wnl.0000000000004608
