Cited by 72Traumatic Brain Injury ResearchDementia and Cognitive Impairment ResearchTraumatic Brain Injury and Neurovascular Disturbances

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Traumatic brain injury may not increase the risk of Alzheimer disease

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Weiner, Michael W., Crane, Paul K., Montine, Thomas J., Bennett, David A., Veitch, Dallas P.·2017·Neurology

DOI 10.1212/wnl.0000000000004608PMC PMC5664292

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Abstract

Traumatic brain injury (TBI) commonly occurs in civilian and military populations. Some epidemiologic studies previously have associated TBI with an increased risk of Alzheimer disease (AD). Recent clinicopathologic and biomarker studies have failed to confirm the relationship of TBI to the development of AD dementia or pathologic changes, and suggest that other neurodegenerative processes might be linked to TBI. Additional studies are required to determine the long-term consequences of TBI.

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Additional file 1 of Prediction of conversion from mild cognitive impairment to Alzheimer’s disease and simultaneous feature selection and grouping using Medicaid claim data
Zhang, Q., Coury, R., & Tang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26691178
Additional file 1 of Amyloid PET across the cognitive spectrum in former professional and college American football players: findings from the DIAGNOSE CTE Research Project
Stern, R. A., Trujillo‐Rodriguez, D., Tripodis, Y., Pulukuri, S. V., Alosco, M. L., Adler, C. H., Balcer, L. J., Bernick, C. B., Baucom, Z., MAREK, K. L., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24257416
Additional file 2 of Prediction of conversion from mild cognitive impairment to Alzheimer’s disease and simultaneous feature selection and grouping using Medicaid claim data
Zhang, Q., Coury, R., & Tang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26691181
Recherche de facteurs associés à la maladie d’Alzheimer par réutilisation de base de données massives
Rochoy, M. (2019) · theses.fr (ABES) · doi:10.70675/4560bf49z9fd2z42a9z83e6zdd4b8e4e87ea
Traumatic brain injury and post-traumatic stress disorder on brain imaging markers and cognition in a war veterans population
Sibilia, F., Fotouhi, M., Lei, X., Cabeen, R. P., Cen, S., Choupan, J., Hazany, S., Sheikh‐Bahaei, N., & Initiative, A. D. N. (2026) · Journal of Alzheimer s Disease · doi:10.1177/13872877261450973

Authors: Weiner, M. W., Crane, P. K., Montine, T. J., Bennett, D. A., & Veitch, D. P.
Affiliations: Rush University Medical Center (US)
Corresponding author: Weiner, Michael W.
ORCID: Weiner, Michael W.
Crane, Paul K.
Montine, Thomas J.
Bennett, David A.
Veitch, Dallas P.
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2017-10-31
Volume: 89
Issue: 18
Pages: 1923-1925
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.0000000000004608
PMC: PMC5664292
OpenAlex: W2763169728
Cited by: 71
References: 19
Citations by year: 2026: 1 · 2025: 3 · 2024: 6 · 2023: 6 · 2022: 9 · 2021: 14 · 2020: 9 · 2019: 14 · 2018: 8 · 2017: 1
FWCI: 6.86
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
Locations: Neurology (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
eScholarship (California Digital Library) (submittedVersion, cc-by-nc-nd)
Funders: U.S. Department of Defense
Alzheimer's Disease Neuroimaging Initiative
National Institute on Aging (R01AG017917, R01AG015819, RF1AG015819)
Topics: Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
Keywords: traumatic brain injury, Alzheimer's disease, dementia risk, neurodegeneration, biomarkers, clinicopathological correlation, military personnel, civilian trauma
MeSH terms: Brain Injuries, Traumatic, Alzheimer Disease, Humans, Risk Factors

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Traumatic brain injury may not increase the risk of Alzheimer disease

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