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Cited by 187

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Subthalamic nucleus stimulation in Parkinson disease induces apathy: A PET study

Open access
Le Jeune, F., Drapier, D., Bourguignon, A., Péron, J., Mesbah, H., Drapier, S., Sauleau, P., Haegelen, C., Travers, D., Garin, E., Malbert, C. H., Millet, B., Vérin, M.·2009·Neurology

Abstract

OBJECTIVE: Apathy may be induced by subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson disease (PD). We therefore wished to test the hypothesis that apathy induced by STN-DBS correlates with changes in glucose metabolism, using (18)FDG-PET. METHODS: Twelve patients with PD were assessed 3 months before (M-3) and 3 months after (M+3) STN-DBS with (18)FDG-PET and the Apathy Evaluation Scale. RESULTS: Apathy had significantly worsened at M+3 after STN-DBS. Positive correlations were observed between this variation in apathy scores and changes in glucose metabolism, especially in the right frontal middle gyrus (Brodmann area [BA] 10) and right inferior frontal gyrus (BA 46 and BA 47). Negative correlations between the two were observed in the right posterior cingulate gyrus (BA 31) and left medial frontal lobe (BA 9). CONCLUSION: These preliminary results confirm the role of the subthalamic nucleus in associative and limbic circuitry in humans and suggest that it is a key basal ganglia structure in motivation circuitry.

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Metadata

Authors
Le Jeune, F., Drapier, D., Bourguignon, A., Péron, J., Mesbah, H., Drapier, S., Sauleau, P., Haegelen, C., Travers, D., Garin, E., Malbert, C. H., Millet, B., & Vérin, M.
Venue
Neurology
Published
2009-11-24
Volume
73
Issue
21
Pages
1746-1751
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2146508747
Cited by
187
References
4
FWCI
9.75
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Subthalamic nucleus stimulation in Parkinson disease induces apathy: A PET study. https://app.cochat.ai/papers/10.1212/wnl.0b013e3181c34b34
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Le Jeune, F., Drapier, D., Bourguignon, A., Péron, J., Mesbah, H., Drapier, S., Sauleau, P., Haegelen, C., Travers, D., Garin, E., Malbert, C. H., Millet, B., & Vérin, M. (2009). Subthalamic nucleus stimulation in Parkinson disease induces apathy: A PET study. Neurology. https://doi.org/10.1212/wnl.0b013e3181c34b34

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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