The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Late recovery after traumatic, anoxic, or hemorrhagic long-lasting vegetative state
Abstract
OBJECTIVES: Late recovery of awareness in vegetative state (VS) is considered as an exceptional outcome, and has been reported prevalently after traumatic brain injury (TBI). The present prospective study aimed to verify frequency of late recovery (later than 1 year postonset in TBI and 3 months postonset in patients without TBI) of responsiveness and consciousness in traumatic and nontraumatic long-lasting (more than 6 months after onset) VS. METHODS: Fifty inpatients with long-lasting VS (36% TBI, 36% hemorrhagic, and 28% anoxic) were enrolled and followed up for a mean of 25.7 months from onset (5 patients for more than 4 years). Level of responsiveness and functional disability were evaluated by means of validated scales (Coma Recovery Scale-Revised and Disability Rating Scale). RESULTS: At the end of the study, 21 patients (42%) had died, 17 patients (34%) were in VS, and 2 patients with TBI (4%) had recovered responsiveness within 12 months postonset. The remaining 10 (20%) patients with TBI and patients without TBI showed late recovery of responsiveness; 6 of them (12%) further progressed to consciousness. Late recovery was significantly associated with younger age and was relatively more frequent in TBI. Functional abilities were severely impaired in all patients. CONCLUSIONS: This clinical study demonstrates that late recovery of responsiveness and consciousness is not exceptional in patients with traumatic and nontraumatic VS, although with residual severe disability.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The minimally conscious state: Definition and diagnostic criteria
Giacino, J. T., Ashwal, S., Childs, N., Cranford, R., Jennett, B., Katz, D. I., Kelly, J. P., Rosenberg, J. H., Whyte, J., Zafonte, R. D., et al. (2002) · Neurology · doi:10.1212/wnl.58.3.349 · Cited by 2,422
Giacino, J. T., Kalmar, K., & Whyte, J. (2004) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2004.02.033 · Cited by 1,874
Medical Aspects of the Persistent Vegetative State
(1994) · New England Journal of Medicine · doi:10.1056/nejm199405263302107 · Cited by 1,538
Schnakers, C., Vanhaudenhuyse, A., Giacino, J., Ventura, M., Boly, M., Majerus, S., Moonen, G., & Laureys, S. (2009) · BMC Neurology · doi:10.1186/1471-2377-9-35 · Cited by 1,348
Disability rating scale for severe head trauma: coma to community.
Rappaport, M. B., Hall, K., Hopkins, K. L., Belleza, T., & Cope, D. N. (1982) · PubMed · Cited by 1,093
Misdiagnosis of the vegetative state: retrospective study in a rehabilitation unit: Table 1
Andrews, K., Murphy, L., Munday, R., & Littlewood, C. (1996) · BMJ · doi:10.1136/bmj.313.7048.13 · Cited by 819
Accuracy of diagnosis of persistent vegetative state
Childs, N. L., Mercer, W. N., & Childs, H. W. (1993) · Neurology · doi:10.1212/wnl.43.8.1465 · Cited by 540
American Academy of Neurology: No Scientific Evidence That Ultrasound Can Aid in Diagnosis
&NA; (1998) · The Back Letter · doi:10.1097/00130561-199809000-00009 · Cited by 386
Possible axonal regrowth in late recovery from the minimally conscious state
Voss, H. U. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27021 · Cited by 353
Chronic disorders of consciousness
Bernat, J. L. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68508-5 · Cited by 339
Cited by
Giacino, J. T., Katz, D. I., Schiff, N. D., Whyte, J., Ashman, E. J., Ashwal, S., Barbano, R., Hammond, F. M., Laureys, S., Ling, G. S. F., et al. (2018) · Neurology · doi:10.1212/wnl.0000000000005926 · Cited by 773
Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies
Edlow, B. L., Claassen, J., Schiff, N. D., & Greer, D. M. (2021) · Nature Reviews Neurology · doi:10.1038/s41582-020-00428-x · Cited by 731
Stender, J., Gosseries, O., Bruno, M.-A., Charland-Verville, V., Vanhaudenhuyse, A., Demertzi, A., Chatelle, C., Thonnard, M., Thibaut, A., Heine, L., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60042-8 · Cited by 550
Practice Guideline Update Recommendations Summary: Disorders of Consciousness
Giacino, J. T., Katz, D. I., Schiff, N. D., Whyte, J., Ashman, E. J., Ashwal, S., Barbano, R., Hammond, F. M., Laureys, S., Ling, G. S. F., et al. (2018) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2018.07.001 · Cited by 269
Metadata
- Authors
- Estraneo, A., Moretta, P., Loreto, V., Lanzillo, B., Santoro, L., & Trojano, L.
- Venue
- Neurology
- Published
- 2010-07-20
- Volume
- 75
- Issue
- 3
- Pages
- 239-245
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2093765285
- Cited by
- 300
- References
- 27
- FWCI
- 12.79
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Late recovery after traumatic, anoxic, or hemorrhagic long-lasting vegetative state. https://app.cochat.ai/papers/10.1212/wnl.0b013e3181e8e8cc
- The paper
- Estraneo, A., Moretta, P., Loreto, V., Lanzillo, B., Santoro, L., & Trojano, L. (2010). Late recovery after traumatic, anoxic, or hemorrhagic long-lasting vegetative state. Neurology. https://doi.org/10.1212/wnl.0b013e3181e8e8cc
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
