Cited by 369Dementia and Cognitive Impairment ResearchCancer-related cognitive impairment studiesAlzheimer's disease research and treatments

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Reversion from mild cognitive impairment to normal or near-normal cognition: Risk factors and prognosis

Open access

Koepsell, Thomas D., Monsell, Sarah E.·2012·Neurology

DOI 10.1212/wnl.0b013e31826e26b7PMC PMC3475624

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVES: We sought to identify characteristics of individuals with mild cognitive impairment (MCI) that are associated with a relatively high probability of reverting back to normal cognition, and to estimate the risk of future cognitive decline among those who revert. METHODS: We first studied 3,020 individuals diagnosed with MCI on at least 1 visit to an Alzheimer's Disease Center in the United States. All underwent standardized Uniform Data Set evaluations at their first visit with an MCI diagnosis and on a subsequent visit, about 1 year later, at which cognitive status was reassessed. Multiple logistic regression was used to identify predictors of reverting from MCI back to normal cognition. We then estimated the risk of developing MCI or dementia over the next 3 years among those who had reverted, compared with individuals who had not had a study visit with MCI. RESULTS: About 16% of subjects diagnosed with MCI reverted back to normal or near-normal cognition approximately 1 year later. Five characteristics assessed at the first MCI visit contributed significantly to a model predicting a return to normal cognition: Mini-Mental State Examination (MMSE) score, Clinical Dementia Rating (CDR) score, MCI type, Functional Activities Questionnaire (FAQ) score, and APOE ε4 status. Survival analysis showed that the risk of retransitioning to MCI or dementia over the next 3 years was sharply elevated among those who had MCI and then improved, compared with individuals with no history of MCI. CONCLUSIONS: Even in a cohort of patients seen at dementia research centers, reversion from MCI was fairly common. Nonetheless, those who reverted remained at increased risk for future cognitive decline.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1212/wnl.0b013e31826e26b7

Cites

28 of 28 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

“Mini-mental state”
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
Model selection and multimodel inference: a practical information-theoretic approach.
Guthery, F. S., Burnham, K. P., & Anderson, D. R. (2003) · The Journal of Wildlife Management · doi:10.2307/3802723 · Cited by 41,495
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS‐ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
Longitudinal data analysis using generalized linear models
LIANG, K.-Y., & ZEGER, S. L. (1986) · Biometrika · doi:10.1093/biomet/73.1.13 · Cited by 18,550
Statistical Analysis With Missing Data
Lahiff, M., Little, R. J. A., & Rubin, D. B. (1989) · Journal of the American Statistical Association · doi:10.2307/2289883 · Cited by 17,385
The Clinical Dementia Rating (CDR): Current version and scoring rules
Morris, J. C. (1993) · Neurology · doi:10.1212/wnl.43.11.2412-a · Cited by 9,882
Mild cognitive impairment as a diagnostic entity
Petersen, R. C. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01388.x · Cited by 7,864
Untitled work
Sheikh (1986) · doi:10.1300/j018v05n01_09 · Cited by 7,236
Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium
McKeith, I. G., Dickson, D. W., Lowe, J., Emre, M., O'Brien, J. T., Feldman, H., Cummings, J., Duda, J. E., Lippa, C., Perry, E. K., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000187889.17253.b1 · Cited by 5,069
Vascular dementia: Diagnostic criteria for research studies: Report of the NINDS‐AIREN International Workshop*
Román, G. C., Tatemichi, T. K., Erkinjuntti, T., Cummings, J. L., Masdeu, J. C., Garcia, J. H., Amaducci, L., Orgogozo, J.-M., Brun, A., Hofman, A., et al. (1993) · Neurology · doi:10.1212/wnl.43.2.250 · Cited by 4,921

Show all 28 references

Sorted by citations

Items 101–200 of 367

Prediction of Alzheimer’s Disease Dementia: Data from the GuidAge Prevention Trial
Stefano, F. D., for the GuidAge study group, Epelbaum, S., Coley, N., Cantet, C., Ousset, P., Hampel, H. J., Bakardjian, H., Lista, S., Vellas, B. J., et al. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150013 · Cited by 37
Personality traits, cognitive states, and mortality in older adulthood.
Yoneda, T. B., Graham, E. K., Lozinski, T., Bennett, D. A., Mroczek, D. K., Piccinin, A. M., Hofer, S. M., & Terrera, G. M. (2022) · Journal of Personality and Social Psychology · doi:10.1037/pspp0000418 · Cited by 41
Apathy as a Predictor for Conversion From Mild Cognitive Impairment to Dementia: A Systematic Review and Meta-Analysis of Longitudinal Studies
Fresnais, D., Humble, M. B., Bejerot, S., Meehan, A. D., & Fure, B. (2022) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/08919887221093361 · Cited by 37
Mild Cognitive Impairment
Oh, E., & Lee, A. Y. (2016) · Journal of the Korean Neurological Association · doi:10.17340/jkna.2016.3.1 · Cited by 33
Cigarette smoking and cognitive function among older adults living in the community
Amini, R., Sahli, M., & Ganai, S. (2020) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2020.1806199 · Cited by 34
Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients
Zuliani, G., Polastri, M., Romagnoli, T., Marabini, L., Seripa, D., Cervellati, C., Zurlo, A., Passaro, A., & Brombo, G. (2020) · Aging Clinical and Experimental Research · doi:10.1007/s40520-020-01697-8 · Cited by 33
Cost-effectiveness of using amyloid positron emission tomography in individuals with mild cognitive impairment
Lee, Y.-S., Youn, H., Jeong, H., Lee, T.-J., Han, J. W., Park, J. H., & Kim, K. W. (2021) · Cost Effectiveness and Resource Allocation · doi:10.1186/s12962-021-00300-9 · Cited by 33
Art therapy and music reminiscence activity in the prevention of cognitive decline: study protocol for a randomized controlled trial
Mahendran, R., Rawtaer, I., Fam, J., Wong, J., Kumar, A. P., Gandhi, M., Jing, K. X., Feng, L., & Kua, E. H. (2017) · Trials · doi:10.1186/s13063-017-2080-7 · Cited by 33
Anterior cingulate cortex mediates the relationship between O3PUFAs and executive functions in APOE e4 carriers
Zamroziewicz, M. K., Paul, E. J., Rubin, R. D., & Barbey, A. K. (2015) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2015.00087 · Cited by 34
Discovery of a Metabolic Signature Predisposing High Risk Patients with Mild Cognitive Impairment to Converting to Alzheimer’s Disease
Huang, Y., Lin, C., Tsai, T.-H., Huang, C., Li, J.-L., Chen, L., Li, C., Tsai, T., & Wang, P.-N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222010903 · Cited by 33
Driving and dementia: a clinical decision pathway
Carter, K., Monaghan, S., O'Brien, J. T., Teodorczuk, A., Mosimann, U. P., & Taylor, J. (2014) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4132 · Cited by 32
APOE-Sensitive Cholinergic Sprouting Compensates for Hippocampal Dysfunctions Due to Reduced Entorhinal Input
Bott, J.-B., Héraud, C., Cosquer, B., Herbeaux, K., Aubert, J., Sartori, M., Goutagny, R., & Mathis, C. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1174-16.2016 · Cited by 34
Systematic Review: microRNAs as Potential Biomarkers in Mild Cognitive Impairment Diagnosis
Ogonowski, N. S., Salcidua, S., León, T., Chamorro-Veloso, N., Valls, C., Avalos, C., Bisquertt, A., Rentería, M. E., Orellana, P., & Duran-Aniotz, C. A. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.807764 · Cited by 35
The Clinical Course of Early and Late Mild Cognitive Impairment
Lin, S., Lin, P., Lin, Y., Lee, Y., Wang, C., Peng, S.-W., & Wang, P. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.685636 · Cited by 34
Modifiable risk factors for mild cognitive impairment among cognitively normal community-dwelling older adults: A systematic review and meta-analysis
He, C. Y. Y., Zhou, Z., Kan, M. M. P., Chan, D. H. Y., Wong, A. C. T., Mok, K. H. Y., Lam, F. M. H., Chan, S. C. C., Cheung, C. K. C., Yeung, M. K. C., et al. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102350 · Cited by 36
Mild cognitive impairment reverters have a favorable cognitive prognosis and cortical integrity in Parkinson's disease
Chung, S. J., Park, Y.-H., Yoo, H. S., Lee, Y. H., Ye, B. S., Sohn, Y. H., Lee, J., & Lee, P. H. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.02.023 · Cited by 30
Brain Metabolism and Microglia Activation in Mild Cognitive Impairment: A Combined [18F]FDG and [11C]-(R)-PK11195 PET Study
Tondo, G., Boccalini, C., Caminiti, S. P., Presotto, L., Filippi, M., Magnani, G., Frisoni, G. B., Iannaccone, S., & Perani, D. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201351 · Cited by 29
Neuropsychological Changes in Isolated REM Sleep Behavior Disorder: A Systematic Review and Meta-analysis of Cross-sectional and Longitudinal Studies
Leitner, C., D’Este, G., Verga, L., Rahayel, S., Mombelli, S., Sforza, M., Casoni, F. M., Zucconi, M., Ferini‐Strambi, L., & Galbiati, A. (2023) · Neuropsychology Review · doi:10.1007/s11065-022-09572-1 · Cited by 30
Life expectancy with and without dementia in persons with mild cognitive impairment in the community
Mooldijk, S. S., Yaqub, A., Wolters, F. J., Licher, S., Koudstaal, P. J., Ikram, M. K., & Ikram, M. A. (2021) · Journal of the American Geriatrics Society · doi:10.1111/jgs.17520 · Cited by 28
Alzheimer disease biomarkers and insights into mild cognitive impairment
Knopman, D. S. (2013) · Neurology · doi:10.1212/wnl.0b013e31828728ac · Cited by 28
A promising tool to explore functional impairment in neurodegeneration: A systematic review of near-infrared spectroscopy in dementia.
Butters, E., Srinivasan, S., O'Brien, J. T., Su, L., & Bale, G. M. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101992 · Cited by 29
Instrumental Activities of Daily Living, Neuropsychiatric Symptoms, and Neuropsychological Impairment in Mild Cognitive Impairment
Ginsberg, T. B., Powell, L. A., Emrani, S., Wasserman, V., Higgins, S., Chopra, A., Cavalieri, T. A., & Libon, D. J. (2019) · Journal of Osteopathic Medicine · doi:10.7556/jaoa.2019.015 · Cited by 28
Diabetes and Prediabetes Inhibit Reversion from Mild Cognitive Impairment to Normal Cognition
Makino, K., Lee, S., Bae, S., Chiba, I., Harada, K., Katayama, O., Shinkai, Y., Makizako, H., & Shimada, H. (2021) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2021.02.033 · Cited by 32
Predicting conversion to Alzheimer’s disease in individuals with Mild Cognitive Impairment using clinically transferable features
Rye, I., Vik, A., Kociński, M., Lundervold, A. S., & Lundervold, A. J. (2022) · Scientific Reports · doi:10.1038/s41598-022-18805-5 · Cited by 31
Is there an MCI reversion to cognitively normal? Analysis of Alzheimer's disease biomarkers profiles
Park, M. H., & Han, C. (2014) · International Psychogeriatrics · doi:10.1017/s1041610214002129 · Cited by 29
Effects of aerobic exercise on global cognitive function and sleep in older adults with mild cognitive impairment: A systematic review and meta-analysis
Ahn, J., & Kim, M. (2023) · Geriatric Nursing · doi:10.1016/j.gerinurse.2023.02.008 · Cited by 29
Classifying MCI Subtypes in Community-Dwelling Elderly Using Cross-Sectional and Longitudinal MRI-Based Biomarkers
Guan, H., Liu, T., Jiang, J., Tao, D., Zhang, J., Niu, H., Zhu, W., Wang, Y., Cheng, J., Kochan, N. A., et al. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00309 · Cited by 30
Longitudinal structural MRI-based deep learning and radiomics features for predicting Alzheimer’s disease progression
Aghajanian, S., Mohammadifard, F., Mohammadi, I., Firouzabadi, S. R., Bagheri, A. B., Ghaffary, E. M., & Mirmosayyeb, O. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01827-2 · Cited by 25
Effects of combined training on neuropsychiatric symptoms and quality of life in patients with cognitive decline
Cintoli, S., Radicchi, C., Noale, M., Maggi, S., Meucci, G., Tognoni, G., Bonuccelli, U., Sale, A., Berardi, N., & Maffei, L. (2019) · Aging Clinical and Experimental Research · doi:10.1007/s40520-019-01280-w · Cited by 26
Prevalence of Memory-Related Diagnoses Among U.S. Older Adults With Early Symptoms of Cognitive Impairment
Qian, Y., Chen, X., Tang, D., Kelley, A. S., & Li, J. (2021) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glab043 · Cited by 23
Updates and future perspectives on neuropsychiatric symptoms in Alzheimer's disease
Ruthirakuhan, M. T., Guan, D. X., Mortby, M. E., Gatchel, J. R., & Babulal, G. M. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70079 · Cited by 23
Topological Alterations of the Brain Functional Network in Type 2 Diabetes Mellitus Patients With and Without Mild Cognitive Impairment
Zhou, B., Wang, X., Yang, Q., Wu, F., Tang, L., Wang, J., & Li, C. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.834319 · Cited by 22
Reversion from mild cognitive impairment to normal or near-normal cognition: Risk factors and prognosis
Rosenberg, G. (2013) · Neurology · doi:10.1212/wnl.0b013e31829430ba · Cited by 23
Association between diets and mild cognitive impairment in adults aged 50 years or older
Kim, K. Y., & Yun, J. (2018) · Nutrition Research and Practice · doi:10.4162/nrp.2018.12.5.415 · Cited by 22
Arterial stiffness measured by pulse wave velocity correlated with cognitive decline in hypertensive individuals: a systematic review
Aimagambetova, B., Ariko, T., Merritt, S. S., & Rundek, T. (2024) · BMC Neurology · doi:10.1186/s12883-024-03905-8 · Cited by 21
Predictors That a Diagnosis of Mild Cognitive Impairment Will Remain Stable 3 Years Later
Clem, M. A., Holliday, R. P., Pandya, S. Y., Hynan, L. S., Lacritz, L. H., & Woon, F. L. M. (2017) · Cognitive and Behavioral Neurology · doi:10.1097/wnn.0000000000000119 · Cited by 26
Spontaneous Reversion of Clinical Conditions Measuring the Risk Profile of the Individual: From Frailty to Mild Cognitive Impairment
Canevelli, M., Bruno, G., Remiddi, F., Vico, C., Lacorte, E., Vanacore, N., & Cesari, M. (2017) · Frontiers in Medicine · doi:10.3389/fmed.2017.00184 · Cited by 22
Detection of Mild Cognitive Impairment From Non-Semantic, Acoustic Voice Features: The Framingham Heart Study
Ding, H., Lister, A., Karjadi, C., Au, R., Lin, H., Bischoff, B., & Hwang, P. H. (2024) · JMIR Aging · doi:10.2196/55126 · Cited by 23
Reversion From Mild Cognitive Impairment To Normal Cognition: False-Positive Error Or True Restoration Thanks To Cognitive Control Ability?
Chung, J. Y., Yoon, H., Kim, H., Choi, K. Y., Lee, J. J., Lee, K. H., & Seo, E. H. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s223958 · Cited by 21
Clinical characteristics of older adults with hypertension and unrecognized cognitive impairment
Yamamoto, K. I., Akasaka, H., Yasunobe, Y., Shimizu, A., Nomoto, K., Nagai, K., Umegaki, H., Akasaki, Y., Kojima, T., Kozaki, K., et al. (2022) · Hypertension Research · doi:10.1038/s41440-022-00861-z · Cited by 20
A Multifactor Approach to Mild Cognitive Impairment
Qarni, T., & Salardini, A. (2019) · Seminars in Neurology · doi:10.1055/s-0039-1678585 · Cited by 21
Are Video Games Effective to Promote Cognition and Everyday Functional Capacity in Mild Cognitive Impairment/Dementia Patients? A Meta-Analysis of Randomized Controlled Trials
Ferreira-Brito, F., Ribeiro, F., de Sousa, D. A., Costa, J. N., Caneiras, C. S. G., Carriço, L. M., & Verdelho, A. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210545 · Cited by 20
Measuring emotion recognition: Added value in diagnosing dementia of the Alzheimer’s disease type
Strijkert, F., Huitema, R. B., & Spikman, J. M. (2021) · Journal of Neuropsychology · doi:10.1111/jnp.12263 · Cited by 22
From Evidence to Action: Promoting a Multidimensional Approach to Mild Cognitive Impairment
Canevelli, M., Blasimme, A., Vanacore, N., Bruno, G., & Cesari, M. (2015) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2015.04.013 · Cited by 19
Mild cognitive impairment: A concept analysis
Domínguez-Chávez, C. J., Murrock, C. J., & Salazar-González, B. C. (2018) · Nursing Forum · doi:10.1111/nuf.12299 · Cited by 22
Virtual Reality Meets Non-invasive Brain Stimulation: Integrating Two Methods for Cognitive Rehabilitation of Mild Cognitive Impairment
Mancuso, V., Stramba-Badiale, C., Cavedoni, S., Pedroli, E., Cipresso, P., & Riva, G. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.566731 · Cited by 20
Modifiable Factors Associated with Reversion from Mild Cognitive Impairment to Cognitively Normal Status: A Prospective Cohort Study
Sha, F., Zhao, Z.-Y., Wei, C., Yang, Z., & Li, B. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215677 · Cited by 20
Effects of an empowerment-based educative psycho-behavioral program on neuropsychiatric symptoms among persons with mild cognitive impairment: A mixed methods study
Lin, R. S. Y., Yu, D. S. F., Chau, P. H., & Li, P. W. C. (2022) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2022.104381 · Cited by 18
Mild Cognitive Impairment, Reversion Rates, and Associated Factors: Comparison of Two Diagnostic Approaches
Overton, M., Sjögren, B., Elmståhl, S., & Rosso, A. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-220597 · Cited by 20
The efficacy and mechanism of berberine in improving aging-related cognitive dysfunction: A study based on network pharmacology
Yao, J., Wei, W., Wen, J., Cao, Y., & Li, H. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1093180 · Cited by 20
Cognitive and brain reserve in conversion and reversion in patients with mild cognitive impairment over 12 months of follow-up
Osone, A., Arai, R., Hakamada, R., & Shimoda, K. (2016) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2016.1191620 · Cited by 16
Psychologic/functional forms of memory disorder
Griem, J., Stone, J., Carson, A. J., & Kopelman, M. D. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-801772-2.00035-7 · Cited by 18
The Loss in Expectation of Life due to Early-Onset Mild Cognitive Impairment and Early-Onset Dementia in Norway
Strand, B. H., Knapskog, A., Persson, K., Edwin, T. H., Bjertness, E., Engedal, K., & Selbæk, G. (2019) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000501269 · Cited by 18
Predementia neurocognitive impairment in the elderly
Levin, O. S. (2019) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro201911909210 · Cited by 20
Mild cognitive impairment
Gordon, C. A., & Martin, D. J. (2013) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2013.856265 · Cited by 21
Cognitive decline among European retirees: impact of early retirement, nation-related and personal characteristics
Carmel, S., & Tur‐Sinai, A. (2021) · Ageing and Society · doi:10.1017/s0144686x21000064 · Cited by 18
Psychosocial adjustment to Mild Cognitive Impairment: The role of illness perceptions, cognitive fusion and cognitive impairment.
Guzmán, A., Gillanders, D., Stevenson, A., & Ross, K. (2021) · Dementia · doi:10.1177/1471301219893862 · Cited by 16
Driving cessation and physical frailty in community‐dwelling older adults: A longitudinal study
Ishii, H. H., Doi, T., Tsutsumimoto, K., Nakakubo, S., Kurita, S., & Shimada, H. (2021) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.14272 · Cited by 17
Machine and deep learning algorithms for classifying different types of dementia: A literature review
Noroozi, M., Gholami, M., Sadeghsalehi, H., Behzadi, S., Habibzadeh, A., Erabi, G., Sadatmadani, S.-F., Diyanati, M., Rezaee, A., Dianati, M., et al. (2024) · Applied Neuropsychology Adult · doi:10.1080/23279095.2024.2382823 · Cited by 17
A case of misdiagnosis of mild cognitive impairment: The utility of symptom validity testing in an outpatient memory clinic
Roor, J. J., Dandachi‐FitzGerald, B., & Ponds, R. (2015) · Applied Neuropsychology Adult · doi:10.1080/23279095.2015.1030018 · Cited by 17
Physical Exercise Helped to Maintain and Restore Functioning in Chinese Older Adults With Mild Cognitive Impairment: A 5-Year Prospective Study of the Hong Kong Memory and Ageing Prospective Study (HK-MAPS)
Ma, D. Y., Wong, C., Leung, G. T. Y., Fung, A. W. T., Chan, W. C., & LAM, L. C. W. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2016.10.003 · Cited by 17
Precuneus Structure Changes in Amnestic Mild Cognitive Impairment
Haußmann, R., Werner, A., Gruschwitz, A., Osterrath, A., Lange, J., Donix, K. L., Linn, J., & Donix, M. (2016) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317516678087 · Cited by 17
Genome instability biomarkers and blood micronutrient risk profiles associated with mild cognitive impairment and Alzheimer's disease
Lee, S. L., Thomas, P., & Fenech, M. F. (2015) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2014.12.012 · Cited by 18
Mindfulness-Based Training Does Not Improve Neuropsychological Outcomes in Mild Cognitive Impairment More Than Spontaneous Reversion Rates: A Randomized Controlled Trial
Doshi, K., Henderson, S. L., Fan, Q., Wong, K. F., & Lim, J. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-215035 · Cited by 16
Handgrip strength, physical activity and incident mild cognitive impairment and dementia
Werneck, A. O., Araújo, R. H. D. O., da Silva, D. R. P., & Vancampfort, D. (2023) · Maturitas · doi:10.1016/j.maturitas.2023.107789 · Cited by 18
The Efficacy of Cognitive Training on Neuropsychological Outcomes in Mild Cognitive Impairment: A Meta-Analysis
Raimo, S., Cropano, M., Gaita, M., Maggi, G., Cavallo, N. D., Roldán-Tapia, L., & Santangelo, G. (2023) · Brain Sciences · doi:10.3390/brainsci13111510 · Cited by 16
Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment
Li, Z., Heckman, M. G., Kanekiyo, T., Martens, Y. A., Day, G. S., Vassilaki, M. E., Liu, C., Bennett, D. A., Petersen, R. C., Zhao, N., et al. (2022) · Neurology · doi:10.1212/wnl.0000000000200387 · Cited by 16
Vascular Health and Genetic Risk Affect Mild Cognitive Impairment Status and 4-Year Stability: Evidence From the Victoria Longitudinal Study
DeCarlo, C. A., MacDonald, S. W. S., Vergote, D., Jhamandas, J. H., Westaway, D. A., & Dixon, R. A. (2015) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbv043 · Cited by 16
Predicting progression of amnesic MCI: The integration of episodic memory impairment with perfusion SPECT
Quaranta, D., Gainotti, G., Giuda, D. D., Vita, M. G., Cocciolillo, F., Lacidogna, G., Guglielmi, V., Masullo, C., Giordano, A., & Marra, C. (2017) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2017.10.008 · Cited by 17
Dietary Habits Modify the Association of Physical Exercise with Cognitive Impairment in Community-Dwelling Older Adults
Wei, K., Yang, J., Lin, S., Mei, Y., An, N., Cao, X., Jiang, L., Liu, C., & Li, C. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11175122 · Cited by 15
Mild cognitive impairment and microbiota: what is known and future perspectives
Gallo, A., Martone, A. M., Liperoti, R., Cipriani, M. C., Ibba, F., Camilli, S., Rognoni, F. M., Landi, F., & Montalto, M. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1410246 · Cited by 15
Utilization of healthcare services among elderly with cognitive impairment no dementia and influence of depression and anxiety: a longitudinal study
St-Hilaire, A., Hudon, C., Préville, M., & Potvin, O. (2016) · Aging & Mental Health · doi:10.1080/13607863.2016.1161006 · Cited by 15
Progression from Subjective Cognitive Decline to Mild Cognitive Impairment or Dementia: The Role of Baseline Cognitive Performance
Jester, D. J., Vyhnálek, M., Andel, R., Marková, H., Nikolai, T., Laczó, J., Matušková, V., Čechová, K., Sheardová, K., & Hort, J. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215291 · Cited by 15
Stability of Montreal Cognitive Assessment in Individuals with Mild Cognitive Impairment: Potential Influence of Practice Effect
Lei, K. S., Lam, B. Y., Lai, D. W. L., Bai, X., Li, J. C. M., Zou, Z., & Chan, C. C. H. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-220003 · Cited by 14
A Comparison of Operational Definitions for Mild Cognitive Impairment
Polcher, A. A., Wolfsgruber, S., Peters, O., Frölich, L., Wiltfang, J., Kornhuber, J., Hüll, M., Rüther, E., Lewczuk, P., Maier, W., et al. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215548 · Cited by 17
Effectiveness of mindfulness‐based interventions on mental, cognitive outcomes and neuroplastic changes in older adults with mild cognitive impairment: A systematic review and meta‐analysis
Leow, Y., Rashid, N. L. A., Klainin‐Yobas, P., Zhang, Z., & Wu, X. V. (2023) · Journal of Advanced Nursing · doi:10.1111/jan.15720 · Cited by 14
Deep learning for risk-based stratification of cognitively impaired individuals
Romano, M. F., Zhou, X., Balachandra, A. R., Jadick, M. F., Qiu, S., Nijhawan, D. A., Joshi, P. S., Mohammad, S., Lee, P. H., Smith, M. J., et al. (2023) · iScience · doi:10.1016/j.isci.2023.107522 · Cited by 13
Alzheimer disease biomarkers may aid in the prognosis of MCI cases initially reverted to normal
Vermunt, L., van Paasen, A. J. L., Teunissen, C. E., Scheltens, P., Visser, P. J., Tijms, B. M., & Initiative, A. D. N. (2019) · Neurology · doi:10.1212/wnl.0000000000007609 · Cited by 14
Non-linear association between serum spermidine and mild cognitive impairment: Results from a cross-sectional and longitudinal study
Xu, J., Sun, Z., Zhang, R., Li, R., Yu, Z., Zhang, Q., Ma, Y., Xing, F., & Zheng, L. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.924984 · Cited by 16
Transcriptomic predictors of rapid progression from mild cognitive impairment to Alzheimer's disease
Huang, Y.-L., Tsai, T.-H., Shen, Z.-Q., Chan, Y.-H., Tu, C.-W., Tung, C.-Y., Wang, P.-N., & Tsai, T.-F. (2025) · Alzheimer's Research & Therapy · doi:10.1186/s13195-024-01651-0 · Cited by 13
Social network and the risk for developing mild cognitive impairment and dementia among older adults
Eymundsdóttir, H., SIGURDARDOTTIR, S. T., Ramel, A., Jónsson, P. V., Gudnason, V. G., Launer, L. J., & Chang, M. (2022) · Aging Clinical and Experimental Research · doi:10.1007/s40520-022-02150-8 · Cited by 13
Predicting the reversion from mild cognitive impairment to normal cognition based on magnetic resonance imaging, clinical, and neuropsychological examinations
Yu, H., Tan, C., Huang, S.-J., Zhang, X.-H., Tan, L., & Xu, W. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.03.009 · Cited by 14
MRI-based mild cognitive impairment and Alzheimer's disease classification using an algorithm of combination of variational autoencoder and other machine learning classifiers
Bit, S., Dey, P., Maji, A., Initiative, A. D. N., & Khan, T. K. (2024) · Journal of Alzheimer s Disease Reports · doi:10.1177/25424823241290694 · Cited by 14
Investigation of Possible Correlation Between Retinal Neurovascular Biomarkers and Early Cognitive Impairment in Patients With Chronic Kidney Disease
Peng, S.-Y., Wu, I., Sun, C., Lee, C., Liu, C., Lin, Y., & Yeung, L. (2021) · Translational Vision Science & Technology · doi:10.1167/tvst.10.14.9 · Cited by 14
Factors affecting reversion from mild cognitive impairment to normal cognition in midlife to later life in Korea: A national population study
Jang, A. R., & Yoon, J. Y. (2019) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.13783 · Cited by 12
A household survey of the prevalence of subjective cognitive decline and mild cognitive impairment among urban community-dwelling adults aged 30 to 65
Pinyopornpanish, K., Buawangpong, N., Soontornpun, A., Thaikla, K., Pateekhum, C., Nantsupawat, N., Wiwatkunupakarn, N., Jiraporncharoen, W., & Angkurawaranon, C. (2024) · Scientific Reports · doi:10.1038/s41598-024-58150-3 · Cited by 11
Dissecting the clinical and pathological prognosis of MCI patients who reverted to normal cognition: a longitudinal study
Yu, H., Tan, L., Jiao, M.-J., Lv, Y.-J., Zhang, X.-H., Tan, C., Xu, W., & Initiative, A. D. N. (2025) · BMC Medicine · doi:10.1186/s12916-025-04092-0 · Cited by 15
Conversion pattern and predictive factor of mild cognitive impairment in elderly Koreans
Shim, S.-M., Song, J., Kim, J., & Jeon, J. (2016) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2016.02.007 · Cited by 11
A Longitudinal Study Examining Self-Regulation Practices in Older Drivers with and without Suspected Mild Cognitive Impairment
Feng, Y. R., Meuleners, L. B., Stevenson, M., Heyworth, J. S., Murray, K., Fraser, M. L., & Maher, S. (2021) · Clinical Interventions in Aging · doi:10.2147/cia.s336802 · Cited by 11
Functional Profile of Older Adults Hospitalized in Rehabilitation Units of the National Network of Integrated Continuous Care of Portugal: A Longitudinal Study
da Fonseca, C. J. V., Ramos, A., de Pinho, L. G., Morgado, B., Oliveira, H. J. M., & Lopes, M. J. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12111937 · Cited by 10
Escalas de tamizaje cognitivo en habla hispana: una revisión crítica
Torres‐Castro, S., Mena‐Montes, B., González-Ambrosio, G., Zubieta-Zavala, A., Torres‐Carrillo, N., Acosta, I., & Espinel‐Bermúdez, M. C. (2018) · Neurología · doi:10.1016/j.nrl.2018.03.009 · Cited by 11
Citicoline May Prevent Cognitive Decline in Patients with Cerebrovascular Disease
Almería, M., Álvarez, I., Molina‐Seguin, J., Besora, S., Buongiorno, M., Romero, S., Casas, L., Cano, C., Castejón, J., Arribas, S., et al. (2023) · Clinical Interventions in Aging · doi:10.2147/cia.s409994 · Cited by 10
Predictors and outcomes of fluctuations in the clinical dementia rating scale
Wilks, H., Benzinger, T. L. S., Schindler, S. E., Cruchaga, C., Morris, J. C., & Hassenstab, J. J. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13679 · Cited by 11
Trajectories of general and central obesity beyond middle age in relation to late‐life cognitive decline and dementia
Liang, Z., Qin, H., Su, B., Bao, Y., Vitiello, M. V., Hu, G., & Wang, Y. (2025) · Obesity · doi:10.1002/oby.24208 · Cited by 9
Biological Features of Reversion from Mild Cognitive Impairment to Normal Cognition: A Study of Cerebrospinal Fluid Markers and Brain Volume
Moradi, K., Faghani, S., Abdolalizadeh, A., Khomeijani-Farahani, M., Ashraf‐Ganjouei, A., & Initiative, A. D. N. (2021) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-200229 · Cited by 10
Computer use and cognitive decline among Japanese older adults: A prospective cohort study
Kurita, S., Doi, T., Tsutsumimoto, K., Nakakubo, S., Ishii, H. H., & Shimada, H. (2021) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2021.104488 · Cited by 10
Do Perceptions of Cognitive Changes Matter in Self-Management Behaviors Among Persons With Mild Cognitive Impairment?
Kim, H., Sereika, S. M., Albert, S. M., Bender, C. M., & Lingler, J. H. (2021) · The Gerontologist · doi:10.1093/geront/gnab129 · Cited by 10
Comparison of Single and Multitask Learning for Predicting Cognitive Decline Based on MRI Data
Imani, V., Prakash, M., Zare, M., & Tohka, J. (2021) · IEEE Access · doi:10.1109/access.2021.3127276 · Cited by 10
Trends in prevalence, health disparities, and early detection of dementia: A 10-year nationally representative serial cross-sectional and cohort study
Lu, K., Xiong, X., Li, M., Yuan, J., Luo, Y., & Friedman, D. B. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2022.1021010 · Cited by 10
Mild cognitive impairment in Aboriginal Australians
Derrig, H., Lavrencic, L. M., Broe, G. A., Draper, B., Cumming, R. G., Garvey, G., Hill, T. Y., Daylight, G., Chalkley, S., Mack, H. A., et al. (2020) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.12054 · Cited by 10

Authors: Koepsell, T. D., & Monsell, S. E.
Affiliations: University of Washington (US)
ORCID: Monsell, Sarah E.
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2012-10-09
Volume: 79
Issue: 15
Pages: 1591-1598
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.0b013e31826e26b7
PMC: PMC3475624
OpenAlex: W2002159622
Cited by: 369
References: 28
Citations by year: 2026: 24 · 2025: 37 · 2024: 29 · 2023: 27 · 2022: 45 · 2021: 31 · 2020: 33 · 2019: 27 · 2018: 23 · 2017: 15 · 2016: 24 · 2015: 22 · 2014: 17 · 2013: 14
FWCI: 12.11
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Neurology (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (AG 016976, U01AG016976, UO1 AG016976)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Keywords: mild cognitive impairment, cognitive decline, dementia risk, Mini-Mental State Examination, Clinical Dementia Rating, APOE ε4, MCI subtypes, Functional Activities Questionnaire, Alzheimer's disease
MeSH terms: Aged, Aged, 80 and over, Female, Humans, Male, Neuropsychological Tests, Prognosis, Remission, Spontaneous, Risk Factors, Disease Progression, Cognitive Dysfunction

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Reversion from mild cognitive impairment to normal or near-normal cognition: Risk factors and prognosis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks