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Cited by 348

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Parkinson's disease in 65 pairs of twins and in a set of quadruplets

Ward, Christopher D., Duvoisin, Roger C., Ince, Susan E., Nutt, John D., Eldridge, Roswell, Calne, Donald B.·1983·Neurology
DOI 10.1212/wnl.33.7.815
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Abstract

Among 43 monozygotic (MZ) and 19 dizygotic (DZ) pairs in which an index case had definite Parkinson's disease (PD), only one MZ pair was definitely concordant for PD. When pairs with questionable clinical features were included, 4 of 48 MZ and 1 of 19 DZ pairs were concordant. The frequency of PD in MZ cotwins of index cases with PD was similar to that expected in an unrelated control group matched for age and sex. Although we were unable to identify a single environmental agent, we conclude that the major factors in the etiology of PD are nongenetic.

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Metadata

Authors
Ward, C. D., Duvoisin, R. C., Ince, S. E., Nutt, J. D., Eldridge, R., & Calne, D. B.
Venue
Neurology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
1983-07
Volume
33
Issue
7
Pages
815-815
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
DOI
10.1212/wnl.33.7.815
OpenAlex
W2007316513
Cited by
348
References
0
FWCI
13.21
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Parkinson's disease in 65 pairs of twins and in a set of quadruplets. https://app.cochat.ai/papers/10.1212/wnl.33.7.815
The paper
Ward, C. D., Duvoisin, R. C., Ince, S. E., Nutt, J. D., Eldridge, R., & Calne, D. B. (1983). Parkinson's disease in 65 pairs of twins and in a set of quadruplets. Neurology. https://doi.org/10.1212/wnl.33.7.815

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.