Cited by 336Dementia and Cognitive Impairment ResearchEpilepsy research and treatmentAlzheimer's disease research and treatments

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Seizures and myoclonus in patients with Alzheimer's disease

Hauser, W. Allen, Morris, Marcia L., Heston, Leonard L., Anderson, V. Elving·1986·Neurology

DOI 10.1212/wnl.36.9.1226

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Abstract

We reviewed 81 patients with dementia and autopsy findings of Alzheimer's disease (AD) to identify patients with seizures or myoclonus after onset of dementia. Eight (10%) had seizures, and eight others (10%) had myoclonus. The incidence of seizures was 10 times more than expected in a reference population. Seizures occurred in any stage of AD, but myoclonus was often a late manifestation. Both seizures and myoclonus, individually or together, are manifestations of AD and may be seen at any time in the course of the illness.

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Authors: Hauser, W. A., Morris, M. L., Heston, L. L., & Anderson, V. E.
Affiliations: University of Minnesota (US)
ORCID: Hauser, W. Allen
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1986-09
Volume: 36
Issue: 9
Pages: 1226-1226
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.36.9.1226
OpenAlex: W2010891279
Cited by: 336
References: 0
Citations by year: 2026: 6 · 2025: 11 · 2024: 8 · 2023: 10 · 2022: 13 · 2021: 15 · 2020: 18 · 2019: 15 · 2018: 12 · 2017: 12 · 2016: 15 · 2015: 11 · 2014: 7 · 2013: 8 · 2012: 18
FWCI: 3.86
Type: journal article
Language: en
Open access: closed
Locations: Neurology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Neurological Disorders and Stroke (1-P50-NS16308, P50NS016308)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Keywords: Alzheimer's disease, seizures, myoclonus, dementia, autopsy findings, seizure incidence, late-stage dementia
MeSH terms: Aged, Alzheimer Disease, Epilepsies, Myoclonic, Humans, Middle Aged, Seizures

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Seizures and myoclonus in patients with Alzheimer's disease

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