Cited by 157Cervical and Thoracic MyelopathyThyroid and Parathyroid SurgerySpine and Intervertebral Disc Pathology

Surgical treatment of cervical spondylotic myelopathy: Time for a controlled trial

Rowland, Lewis P.·1992·Neurology

Abstract

Surgical procedures on the cervical spine are accepted therapies for the myelopathy of cervical spondylosis. However, reported improvement rates vary widely, and many reports indicate improvement in about one-half of the cases. It has not been proven that outcome after surgery is better than the natural history or conservative therapy. Radiographic or imaging evidence of cord impingement or compression may be seen in asymptomatic people. There are no clear guides to the selection of patients who may benefit from the operation and there has been no standardization of preoperative evaluation, trials of conservative therapy, ascertainment of progressive disability, or assessment of outcome. A multicenter controlled trial might answer these questions.

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Crossref · 10.1212/wnl.42.1.5

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  • Results from recent studies assessing the impact of aging on hippocampal and other temporal lobe structures have been variable: some found age-related declines in volume in normal elderly individuals, while others did not.

    “Results from recent studies assessing the impact of aging on hippocampal and other temporal lobe structures have been variable. Some have found age-related declines in volume in normal elderly individuals [4, 30, 31] while others have not [3, 32].”
  • Coffey et al. estimated a rate of volume loss of the amygdala/hippocampus of 0.3%/year.

    “Coffey et al [30] estimated a rate of volume loss of the amygdala/hippocampus of 0.3%/year.”

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Authors
Rowland, L. P.
Affiliations
NewYork–Presbyterian Hospital (US)
Corresponding author
Rowland, Lewis P.
Venue
Neurology
Published
1992-01
Volume
42
Issue
1
Pages
5-5
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2048057683
Cited by
157
References
0
Citations by year
2026: 3 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 4 · 2016: 4 · 2015: 1 · 2014: 5 · 2013: 5 · 2012: 3
FWCI
7.82
Type
journal article
Language
en
Open access
closed
Locations
  • Neurology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • U.S. Public Health Service (GCRC-00645)
  • National Institute of Neurological Disorders and Stroke (NS-11766)
Topics
  • Health Sciences › Medicine › Surgery › Cervical and Thoracic Myelopathy
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Spine and Intervertebral Disc Pathology
Keywords
cervical spondylotic myelopathy, cervical spondylosis, cervical spine surgery, surgical outcomes, conservative treatment, patient selection, preoperative assessment, spinal cord compression, natural history (disease), disability progression
MeSH terms
Animals, Humans, Levodopa, Neurology, Parkinson Disease, Parkinson Disease, Secondary, Selegiline, MPTP Poisoning

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