The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Controlled trial of N-acetylcysteine for patients with probable Alzheimer’s disease
Abstract
The antioxidant N-acetylcysteine (NAC) or placebo was administered in a double-blind fashion to patients who met National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association criteria for probable AD. Testing for efficacy occurred after 3 and 6 months of treatment. Comparison of interval change favored NAC treatment on nearly every outcome measure, although significant differences were obtained only for a subset of cognitive tasks.
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“NAC augmentation of standard treatment in Alzheimer’s disease was associated with improvements in verbal abilities and executive control cognitive tasks compared with controls [157].”
From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [157]
Citations
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Gururaj Joshi, A. (2006) · UKnowledge (University of Kentucky)
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Metadata
- Authors
- Adair, J. C., Knoefel, J. E., & Morgan, N.
- Affiliations
- University of New Mexico (US)
- Venue
- Neurology
- Published
- 2001-10-23
- Volume
- 57
- Issue
- 8
- Pages
- 1515-1517
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2084485820
- Cited by
- 240
- References
- 10
- Citations by year
- 2026: 9 · 2025: 7 · 2024: 10 · 2023: 11 · 2022: 12 · 2021: 11 · 2020: 15 · 2019: 12 · 2018: 11 · 2017: 13 · 2016: 17 · 2015: 13 · 2014: 11 · 2013: 15 · 2012: 10
- FWCI
- 3.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Neurology › Neuroprotection in Cerebral Ischemia
- Keywords
- N-acetylcysteine, Alzheimer's disease, antioxidants, cognitive function, NIA-AA criteria, treatment efficacy
- MeSH terms
- Acetylcysteine, Alzheimer Disease, Double-Blind Method, Female, Humans, Male, Free Radical Scavengers, Treatment Outcome
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