The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
Risk Factors for Postoperative Nausea and Vomiting
Abstract
Knowledge of postoperative nausea and vomiting (PONV) risk factors allows anesthesiologists to optimize the use of prophylactic regimens. Modern PONV risk research began in the 1990s with publication of studies using logistic regression analysis to simultaneously identify multiple independent PONV predictors and publication of meta-analyses and systematic reviews. This literature shows that female gender post-puberty, nonsmoking status, history of PONV or motion sickness, childhood after infancy and younger adulthood, increasing duration of surgery, and use of volatile anesthetics, nitrous oxide, large-dose neostigmine, or intraoperative or postoperative opioids are well established PONV risk factors. Possible risk factors include history of migraine, history of PONV or motion sickness in a child's parent or sibling, better ASA physical status, intense preoperative anxiety, certain ethnicities or surgery types, decreased perioperative fluids, crystalloid versus colloid administration, increasing duration of anesthesia, general versus regional anesthesia or sedation, balanced versus total IV anesthesia, and use of longer-acting versus shorter-acting opioids. Early-phase menstruation, obesity and lack of supplemental oxygen are disproved risk factors. Current risk scoring systems have approximately 55%-80% accuracy in predicting which patient groups will suffer PONV. Further research examining genetic and under-investigated clinical patient characteristics as potential risk factors, and involving outpatients and children, should improve predictive systems.
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Apfel, C. C., Läärä, E., Koivuranta, M., Greim, C.-A., & Roewer, N. (1999) · Anesthesiology · doi:10.1097/00000542-199909000-00022 · Cited by 2,121
Postoperative Nausea and Vomiting: Its Etiology, Treatment, and Prevention
Watcha, M. F., & White, P. F. (1992) · Anesthesiology · doi:10.1097/00000542-199207000-00023 · Cited by 1,728
A Factorial Trial of Six Interventions for the Prevention of Postoperative Nausea and Vomiting
Apfel, C. C., Korttila, K., Abdalla, M., Kerger, H., Turan, A., Vedder, I., Zernak, C., Danner, K., Jokela, R., Pocock, S. J., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032196 · Cited by 1,553
Which Clinical Anesthesia Outcomes Are Important to Avoid? The Perspective of Patients
Macario, A., Weinger, M., Carney, S., & Kim, A. (1999) · Anesthesia & Analgesia · doi:10.1097/00000539-199909000-00022 · Cited by 1,014
Consensus Guidelines for Managing Postoperative Nausea and Vomiting
Gan, T. J., Meyer, T., Apfel, C. C., Chung, F., Davis, P. J., Eubanks, S., Kovac, A., Philip, B. K., Sessler, D. I., Temo, J., et al. (2003) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000068580.00245.95 · Cited by 965
Self-citationGan, T. J., Soppitt, A., Maroof, M., El-Moalem, H., Robertson, K. M., Moretti, E., Dwane, P., & Glass, P. S. A. (2002) · Anesthesiology · doi:10.1097/00000542-200210000-00012 · Cited by 953
Self-citationA survey of postoperative nausea and vomiting
Koivuranta, M., Läärä, E., Snåre, L., & Alahuhta, S. (1997) · Anaesthesia · doi:10.1111/j.1365-2044.1997.117-az0113.x · Cited by 667
Can Postoperative Nausea and Vomiting Be Predicted?
Sinclair, D. R., Chung, F., & Mezei, G. (1999) · Anesthesiology · doi:10.1097/00000542-199907000-00018 · Cited by 651
Apfel, C. C., Kranke, P., Katz, M. H., Goepfert, C., Papenfuss, T., Rauch, S., Heineck, R., Greim, C.-A., & Roewer, N. (2002) · British Journal of Anaesthesia · doi:10.1093/bja/88.5.659 · Cited by 649
Marret, E., Kurdi, O., Zufferey, P., Bonnet, F., & Warltier, D. C. (2005) · Anesthesiology · doi:10.1097/00000542-200506000-00027 · Cited by 577
Cited by
Sugiyama, Y., Suzuki, T., DeStefino, V. J., & Yates, B. J. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00361.2011 · Cited by 30
Joy Lin, Y.-M., Hsu, C.-D., Hsieh, H.-Y., Tseng, C.-C. A., & Sun, H. S. (2014) · Journal of Human Genetics · doi:10.1038/jhg.2014.89 · Cited by 16
Commonly Used Opioids in the Orthopedic Operating Room: A Narrative Review
Nguyen, A., Donnelly, J., Robinson, C. L., & Hasoon, J. (2026) · Orthopedic Reviews · doi:10.52965/001c.158576 · Cited by 3
Metadata
- Authors
- Gan, T. J.
- Venue
- Anesthesia & Analgesia
- Published
- 2006-06
- Volume
- 102
- Issue
- 6
- Pages
- 1884-1898
- ISSN
- 0003-2999 (ISSN-L)
- OpenAlex
- W2055548981
- Cited by
- 666
- References
- 91
- FWCI
- 31.17
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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