The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Propofol Wastage in Anesthesia
Abstract
BACKGROUND: Drug waste has been implicated as a significant contributor to environmental contamination and unnecessary health care costs. METHODS: We collected the contents of pharmaceutical waste collection containers in each of 8 operating rooms, sorted them by hand, and tabulated the results. Propofol returned to the pharmacy was not counted as wasted drug. RESULTS: Wasted or discarded propofol accounted for 45% of all the drug waste. CONCLUSIONS: Propofol does not degrade in nature, accumulates in body fat, and is toxic to aquatic life. We reduced wastage by removing 50 and 100 mL vials of propofol from the pharmacy, retaining only the smallest size (20 mL).
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“Nevertheless, the life-cycle carbon emission is lower than in inhalation anesthesia.”
From A call for immediate climate action in anesthesiology: routine use of minimal or metabolic fresh gas flow reduces our ecological footprint (2023) · cites this paper as [70]
In the citing paper
“Nevertheless, performing TIVA instead of inhalational anesthesia has environmental costs of its own because of the increased disposable plastic waste, higher propofol consumption, and consecutively increased wastage rate.70,71”
From A call for immediate climate action in anesthesiology: routine use of minimal or metabolic fresh gas flow reduces our ecological footprint (2023) · cites this paper as [70]
Citations
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Morgan, T. M. (2001) · PubMed · Cited by 64
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Metadata
- Authors
- Mankes, R. F.
- Affiliations
- Albany Medical College (US)
- Corresponding author
- Mankes, Russell F.
- Venue
- Anesthesia & Analgesia
- Published
- 2012-05
- Volume
- 114
- Issue
- 5
- Pages
- 1091-1092
- ISSN
- 0003-2999 (ISSN-L)
- OpenAlex
- W2018833561
- Cited by
- 140
- References
- 9
- Citations by year
- 2026: 18 · 2025: 13 · 2024: 29 · 2023: 18 · 2022: 16 · 2021: 10 · 2020: 13 · 2019: 7 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 1 · 2014: 4 · 2013: 1 · 2012: 3
- FWCI
- 2.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Anesthesia & Analgesia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Healthcare and Environmental Waste Management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Safe Handling of Antineoplastic Drugs
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
- Keywords
- propofol, pharmaceutical waste, operating room, anesthesia, environmental contamination, waste reduction, aquatic toxicity
- MeSH terms
- Anesthesia, Drug Packaging, Environmental Pollution, Medical Waste, Propofol, Health Care Costs, Medical Waste Disposal, Anesthetics, Intravenous
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