Cited by 140Healthcare and Environmental Waste ManagementSafe Handling of Antineoplastic DrugsAnesthesia and Sedative Agents

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Propofol Wastage in Anesthesia

Mankes, Russell F.·2012·Anesthesia & Analgesia

DOI 10.1213/ane.0b013e31824ea491

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Abstract

BACKGROUND: Drug waste has been implicated as a significant contributor to environmental contamination and unnecessary health care costs. METHODS: We collected the contents of pharmaceutical waste collection containers in each of 8 operating rooms, sorted them by hand, and tabulated the results. Propofol returned to the pharmacy was not counted as wasted drug. RESULTS: Wasted or discarded propofol accounted for 45% of all the drug waste. CONCLUSIONS: Propofol does not degrade in nature, accumulates in body fat, and is toxic to aquatic life. We reduced wastage by removing 50 and 100 mL vials of propofol from the pharmacy, retaining only the smallest size (20 mL).

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Authors: Mankes, R. F.
Affiliations: Albany Medical College (US)
Corresponding author: Mankes, Russell F.
Venue: Anesthesia & Analgesia
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2012-05
Volume: 114
Issue: 5
Pages: 1091-1092
ISSN: 0003-2999 (ISSN-L)
DOI: 10.1213/ane.0b013e31824ea491
OpenAlex: W2018833561
Cited by: 140
References: 9
Citations by year: 2026: 18 · 2025: 13 · 2024: 29 · 2023: 18 · 2022: 16 · 2021: 10 · 2020: 13 · 2019: 7 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 1 · 2014: 4 · 2013: 1 · 2012: 3
FWCI: 2.79
Type: journal article
Language: en
Open access: closed
Locations: Anesthesia & Analgesia (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Healthcare and Environmental Waste Management
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Safe Handling of Antineoplastic Drugs
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
Keywords: propofol, pharmaceutical waste, operating room, anesthesia, environmental contamination, waste reduction, aquatic toxicity
MeSH terms: Anesthesia, Drug Packaging, Environmental Pollution, Medical Waste, Propofol, Health Care Costs, Medical Waste Disposal, Anesthetics, Intravenous

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Propofol Wastage in Anesthesia

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