The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Diffusion Tensor Imaging in Patients With Adult Chronic Idiopathic Hydrocephalus
Abstract
Objective Diffusion tensor imaging (DTI) parameters were investigated in patients with chronic idiopathic hydrocephalus to evaluate microstructural changes of brain tissue caused by chronic ventricular dilatation. Methods Eleven patients fulfilling the criteria for possible or probable idiopathic normal pressure hydrocephalus and 10 healthy control subjects underwent MRI at 3 Tesla, including DTI with 12 gradient directions. Patients were scanned before lumbar cerebrospinal fluid (CSF) withdrawal tests. Differences in fractional anisotropy (FA) and mean diffusivity (MD) between patients and controls were assessed using 2 different methods: manual definition of regions of interest and a fully automated method, TBSS (Tract-Based Spatial Statistics). DTI parameters were correlated with clinical findings. Results Compared with the control group, patients with chronic idiopathic hydrocephalus had significantly higher MD values in both the periventricular corticospinal tract (CST) and the corpus callosum (CC), whereas FA values were significantly higher in the CST but lower in the CC. DTI parameters of the CST correlated with the severity of gait disturbances. Conclusion Microstructural changes in periventricular functionally relevant white matter structures (CSF, CC) in chronic idiopathic hydrocephalus can be visualized using DTI. Further studies should investigate the change of DTI parameters after CSF shunting and its relation to neurologic outcome.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In DTI, patients with iNPH exhibit greater FA within the CST compared with controls (Hattingen et al., 2010)”
From NODDI in clinical research (2020) · cites this paper as Hattingen et al., 2010
Citations
Cites
Advances in functional and structural MR image analysis and implementation as FSL
Smith, S. M., Jenkinson, M., Woolrich, M. W., Beckmann, C. F., Behrens, T. E. J., Johansen-Berg, H., Bannister, P. R., De Luca, M., Drobnjak, I., Flitney, D. E., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.07.051 · Cited by 13,630
Jenkinson, M., Bannister, P., Brady, M., & Smith, S. (2002) · NeuroImage · doi:10.1006/nimg.2002.1132 · Cited by 11,888
Fast robust automated brain extraction
Smith, S. M. (2002) · Human Brain Mapping · doi:10.1002/hbm.10062 · Cited by 10,496
Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data
Smith, S. M., Jenkinson, M., Johansen‐Berg, H., Rueckert, D., Nichols, T. E., Mackay, C. E., Watkins, K. E., Ciccarelli, O., Cader, M. Z., Matthews, P. M., et al. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.02.024 · Cited by 6,598
Nonrigid registration using free-form deformations: application to breast mr images
Rueckert, D., Sonoda, L. I., Hayes, C., Hill, D. L. G., Leach, M. O., & Hawkes, D. J. (1999) · IEEE Transactions on Medical Imaging · doi:10.1109/42.796284 · Cited by 5,265
Le Bihan, D., Breton, E., Lallemand, D., Grenier, P., Cabanis, E., & Laval-Jeantet, M. (1986) · Radiology · doi:10.1148/radiology.161.2.3763909 · Cited by 3,912
Toward a quantitative assessment of diffusion anisotropy
Pierpaoli, C. M., & Basser, P. J. (1996) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910360612 · Cited by 2,392
Localization of the motor hand area to a knob on the precentral gyrus. A new landmark
Yousry, T. A. (1997) · Brain · doi:10.1093/brain/120.1.141 · Cited by 1,840
The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure
Hakim, S., & Adams, R. D. (1965) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(65)90016-x · Cited by 1,265
Diagnosing Idiopathic Normal-pressure Hydrocephalus
Relkin, N. R., Marmarou, A., Klinge, P. M., Bergsneider, M., & Black, P. M. (2005) · Neurosurgery · doi:10.1227/01.neu.0000168185.29659.c5 · Cited by 1,240
Kalbe, E., Kessler, J., Calabrese, P., Smith, R. L., Passmore, A. P., Brand, M., & Bullock, R. M. (2004) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1042 · Cited by 780
Molecular diffusion, tissue microdynamics and microstructure
Bihan, D. L. (1995) · NMR in Biomedicine · doi:10.1002/nbm.1940080711 · Cited by 497
Marmarou, A., Bergsneider, M., Klinge, P. M., Relkin, N. R., & Black, P. M. (2005) · Neurosurgery · doi:10.1227/01.neu.0000168184.01002.60 · Cited by 481
Neuropathological changes caused by hydrocephalus
Bigio, M. R. D. (1993) · Acta Neuropathologica · doi:10.1007/bf00334666 · Cited by 438
Observations on the Pathology of Hydrocephalus
(1949) · Archives of Disease in Childhood · doi:10.1136/adc.24.120.314 · Cited by 326
Diagnosis and management of normal-pressure hydrocephalus
Vanneste, J. A. L. (2000) · Journal of Neurology · doi:10.1007/s004150050003 · Cited by 266
Chronic hydrocephalus in rats and humans: White matter loss and behavior changes
Bigio, M. R. D., Wilson, M. J., & Enno, T. L. (2002) · Annals of Neurology · doi:10.1002/ana.10453 · Cited by 214
Klinge, P. M., Marmarou, A., Bergsneider, M., Relkin, N. R., & Black, P. M. (2005) · Neurosurgery · doi:10.1227/01.neu.0000168187.01077.2f · Cited by 195
Kahlon, B. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.73.6.721 · Cited by 195
Simon, T. J., Ding, L., Bish, J. P., McDonald‐McGinn, D. M., Zackai, E. H., & Gee, J. C. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.11.018 · Cited by 181
Tullberg, M., Hultin, L., EKHOLM, S. E., Månsson, J., Fredman, P., & Wikkelsø, C. (2002) · Acta Neurologica Scandinavica · doi:10.1034/j.1600-0404.2002.01189.x · Cited by 142
Diffusion tensor imaging in hydrocephalus: initial experience.
Assaf, Y., Ben‐Sira, L., Constantini, S., Chang, L., & Beni‐Adani, L. (2006) · PubMed Central · Cited by 141
Krauss, J. K., & Halve, B. (2004) · Acta Neurochirurgica · doi:10.1007/s00701-004-0234-3 · Cited by 127
Three-year survival and functional outcome of patients with idiopathic adult hydrocephalus syndrome
Malm, J., Kristensen, B. W., Stegmayr, B. G., Fagerlund, M., & Koskinen, L. (2000) · Neurology · doi:10.1212/wnl.55.4.576 · Cited by 117
Hakim, C. A., Hakim, R., & Hakim, S. (2001) · Neurosurgery Clinics of North America · doi:10.1016/s1042-3680(18)30033-0 · Cited by 75
Gait apraxia in normal‐pressure hydrocephalus
KNUTSSON, E., & Lying-Tunell, U. (1985) · Neurology · doi:10.1212/wnl.35.2.155 · Cited by 69
Röricht, S., Meyer, B.-U., Woiciechowsky, C., & Lehmann, R. (1998) · Journal of Neurology · doi:10.1007/s004150050219 · Cited by 39
Diffusion imaging in obstructive hydrocephalus.
Uluğ, A. M., Truong, T. N., Filippi, C. G., Chun, T., Lee, J. K., Yang, C., Souweidane, M. M., & Zimmerman, R. D. (2003) · PubMed Central · Cited by 39
Correlations between MRS and DTI in cerebral small vessel disease
Nitkunan, A., McIntyre, D. J. O., Barrick, T. R., O'Sullivan, M. J., Shen, Y., Clark, C. A., Howe, F. A., & Markus, H. S. (2006) · NMR in Biomedicine · doi:10.1002/nbm.1052 · Cited by 30
Yonca Akgoz, A. N. I. K., Demırcı, A., Anık, İ., Etüş, V., & Arslan, A. (2008) · Journal of Computer Assisted Tomography · doi:10.1097/rct.0b013e31812f4edc · Cited by 24
Alteration of diffusion tensor parameters in postmortem brain
Widjaja, E., Wei, X., Vidarsson, L., Moineddin, R., Macgowan, C. K., & Nilsson, D. (2009) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2008.11.009 · Cited by 18
Hähnel, S., Freund, M., Münkel, K., Heiland, S., Jansen, O., Reidel, M. A., & Sartor, K. J. (2000) · Neuroradiology · doi:10.1007/s002340050040 · Cited by 15
Cited by
Sorted by citations
Guidelines for Management of Idiopathic Normal Pressure Hydrocephalus: Second Edition
Mori, E., Ishikawa, M., Kato, T., Kazui, H., Miyake, H., Miyajima, M., Nakajima, M., Hashimoto, M., Kuriyama, N., Tokuda, T., et al. (2012) · Neurologia medico-chirurgica · doi:10.2176/nmc.52.775 · Cited by 666
Nakajima, M., Yamada, S., Miyajima, M., Ishii, K., Kuriyama, N., Kazui, H., Kanemoto, H., SUEHIRO, T., Yoshiyama, K., Kameda, M., et al. (2021) · Neurologia medico-chirurgica · doi:10.2176/nmc.st.2020-0292 · Cited by 612
Kamiya, K., Hori, M., & Aoki, S. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2020.108908 · Cited by 283
“In DTI, patients with iNPH exhibit greater FA within the CST compared with controls (Hattingen et al., 2010), and a few studies have reported a trend of partial normalization”
BackgroundPathogenesis and pathophysiology of idiopathic normal pressure hydrocephalus
Wang, Z., Zhang, Y., Hu, F., Ding, J., & Wang, X. (2020) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13526 · Cited by 173
Normal pressure hydrocephalus—an overview of pathophysiological mechanisms and diagnostic procedures
Skalický, P., Mládek, A., Vlasák, A., de Lacy, P., Beneš, V., & Bradáč, O. (2019) · Neurosurgical Review · doi:10.1007/s10143-019-01201-5 · Cited by 119
Metadata
- Authors
- Hattingen, E., Jurcoane, A., Melber, J., Blasel, S., Zanella, F. E., Neumann-Haefelin, T., & Singer, O. C.
- Affiliations
- Goethe University Frankfurt (DE)
- Venue
- Neurosurgery
- Published
- 2010-05
- Volume
- 66
- Issue
- 5
- Pages
- 917-924
- ISSN
- 0148-396X (ISSN-L)
- OpenAlex
- W1984806874
- Cited by
- 111
- References
- 32
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 8 · 2023: 4 · 2022: 1 · 2021: 7 · 2020: 8 · 2019: 5 · 2018: 5 · 2017: 7 · 2016: 12 · 2015: 8 · 2014: 9 · 2013: 13 · 2012: 9
- FWCI
- 8.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurosurgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Health Sciences › Medicine › Clinical Neurology › Cerebrospinal fluid and hydrocephalus
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Keywords
- idiopathic normal pressure hydrocephalus, diffusion tensor imaging, fractional anisotropy, mean diffusivity, white matter microstructure, corticospinal tract, corpus callosum, gait disturbance, cerebrospinal fluid shunting, tract-based spatial statistics
- MeSH terms
- Aged, Brain, Chronic Disease, Humans, Hydrocephalus, Normal Pressure, Image Interpretation, Computer-Assisted, Middle Aged, Anisotropy, Diffusion Tensor Imaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
