The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Retinoic acid, meiosis and germ cell fate in mammals
Abstract
Although mammalian sex is determined genetically, the sex-specific development of germ cells as sperm or oocytes is initiated by cues provided by the gonadal environment. During embryogenesis, germ cells in an ovary enter meiosis, thereby committing to oogenesis. By contrast, germ cells in a testicular environment do not enter meiosis until puberty. Recent findings indicate that the key to this sex-specific timing of meiosis entry is the presence or absence of the signaling molecule retinoic acid. Although this knowledge clarifies a long-standing mystery in reproductive biology, it also poses many new questions, which we discuss in this review.
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Cites
A decade of molecular biology of retinoic acid receptors
Chambon, P. (1996) · The FASEB Journal · doi:10.1096/fasebj.10.9.8801176 · Cited by 2,889 · cited 2×
“RAR-RXR dimers bind to RAresponse elements (RAREs) and thereby control the expression of RA-responsive genes (Chambon, 1996).”
BackgroundCyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development
Hernandez, R. E., Putzke, A. P., Myers, J. P., Margaretha, L., & Moens, C. B. (2007) · Development · doi:10.1242/dev.02706 · Cited by 245
Cited by
Retinoic acid in development: Towards an integrated view
Niederreither, K., & Dollé, P. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2340 · Cited by 726
Vitamin A in Reproduction and Development
Clagett-Dame, M., & Knutson, D. (2011) · Nutrients · doi:10.3390/nu3040385 · Cited by 439
“male embryo, this pathway is blocked by the action of CYP26B1, but is enabled after birth [70–73].”
BackgroundCytochrome P450s in the Regulation of Cellular Retinoic Acid Metabolism
Catharine Ross, A., & Zolfaghari, R. (2011) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-072610-145127 · Cited by 296
A perspective on the developmental toxicity of inhaled nanoparticles
Hougaard, K. S., Campagnolo, L., Chavatte-Palmer, P., Tarrade, A., Rousseau-Ralliard, D., Valentino, S., Park, M. V. D. Z., de Jong, W. H., Wolterink, G., Piersma, A. H., et al. (2015) · Reproductive Toxicology · doi:10.1016/j.reprotox.2015.05.015 · Cited by 171
Fernández-Pérez, D., Brieño-Enríquez, M. A., Isoler-Alcaraz, J., Larriba, E., & del Mazo, J. (2018) · RNA · doi:10.1261/rna.062869.117 · Cited by 37
Metadata
- Authors
- Bowles, J., & Koopman, P.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2007-10-01
- Volume
- 134
- Issue
- 19
- Pages
- 3401-3411
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2154269795
- Cited by
- 347
- References
- 2
- FWCI
- 10.55
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bowles, J., & Koopman, P. (2007). Retinoic acid, meiosis and germ cell fate in mammals. Development. https://doi.org/10.1242/dev.001107
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