The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Notch signaling in vascular development and physiology
Abstract
Notch signaling is an ancient intercellular signaling mechanism that plays myriad roles during vascular development and physiology in vertebrates. These roles include regulation of artery/vein differentiation in endothelial and vascular smooth muscle cells, regulation of blood vessel sprouting and branching during both normal development and tumor angiogenesis, and the differentiation and physiological responses of vascular smooth muscle cells. Defects in Notch signaling also cause inherited vascular and cardiovascular diseases. In this review, I summarize recent findings and discuss the growing relevance of Notch pathway modulation for therapeutic applications in disease.
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Citations
Cites
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
Gerhardt, H., Golding, M., Fruttiger, M., Ruhrberg, C., Lundkvist, A., Abramsson, A., Jeltsch, M., Mitchell, C., Alitalo, K., Shima, D., et al. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302047 · Cited by 2,894
Angiogenesis as a therapeutic target
Ferrara, N., & Kerbel, R. S. (2005) · Nature · doi:10.1038/nature04483 · Cited by 2,653
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
Joutel, A., Corpechot, C., Ducros, A., Vahedi, K., Chabriat, H., Mouton, P., Alamowitch, S., Domenga, V., Cécillion, M., Maréchal, E., et al. (1996) · Nature · doi:10.1038/383707a0 · Cited by 2,068
Mutations in NOTCH1 cause aortic valve disease
Garg, V., Muth, A. N., Ransom, J. F., Schluterman, M. K., Barnes, R., King, I. N., Grossfeld, P. D., & Srivastava, D. (2005) · Nature · doi:10.1038/nature03940 · Cited by 1,509
Endothelial cells and VEGF in vascular development
Coultas, L., Chawengsaksophak, K., & Rossant, J. (2005) · Nature · doi:10.1038/nature04479 · Cited by 1,016
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
Ridgway, J., Zhang, G., Wu, Y., Stawicki, S., Liang, W.-C., Chanthery, Y., Kowalski, J., Watts, R. J., Callahan, C., Kasman, I., et al. (2006) · Nature · doi:10.1038/nature05313 · Cited by 986
Gale, N. W., Dominguez, M. G., Noguera, I., Pan, L., Hughes, V., Valenzuela, D. M., Murphy, A. J., Adams, N. C., Lin, H. C., Holash, J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407290101 · Cited by 600
Cited by
Chabriat, H., Joutel, A., Dichgans, M., Tournier-Lasserve, E., & Bousser, M.-G. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70127-9 · Cited by 1,088
The Varied Roles of Notch in Cancer
Aster, J. C., Pear, W. S., & Blacklow, S. C. (2017) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-052016-100127 · Cited by 710
Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead
van Hinsbergh, V. W. M., & Koolwijk, P. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvm102 · Cited by 420
Nrarp Coordinates Endothelial Notch and Wnt Signaling to Control Vessel Density in Angiogenesis
Phng, L.-K., Potente, M., Leslie, J. D., Babbage, J., Nyqvist, D., Lobov, I., Ondr, J. K., Rao, S., Lang, R. A., Thurston, G., et al. (2009) · Developmental Cell · doi:10.1016/j.devcel.2008.12.009 · Cited by 349
Liu, H., Kennard, S., & Lilly, B. (2009) · Circulation Research · doi:10.1161/circresaha.108.184846 · Cited by 284
Duan, J., Ruan, B., Yan, X., Liang, L., Song, P., Yang, Z., Liu, Y., Dou, K., Han, H., & Wang, L. (2018) · Hepatology · doi:10.1002/hep.29834 · Cited by 153
The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development
Niessen, K., Zhang, G., Ridgway, J. B., Chen, H., Kolumam, G., Siebel, C. W., & Yan, M. (2011) · Blood · doi:10.1182/blood-2010-11-319129 · Cited by 97
Fang, Z., Ruan, B., Liu, J., Duan, J., Yue, Z., Song, P., Xu, H., Ding, J., Xu, C., Dou, G., et al. (2022) · Hepatology · doi:10.1002/hep.32332 · Cited by 91
Simvastatin increases notch signaling activity and promotes arteriogenesis after stroke
Zacharek, A., Chen, J., Cui, X., Yang, Y., & Chopp, M. (2009) · Stroke · doi:10.1161/strokeaha.108.524116 · Cited by 68
Zhang, Z., Na, H., Gan, Q., Tao, Q., Alekseyev, Y., Hu, J., Yan, Z., Yang, J. B., Tian, H., Zhu, S., et al. (2021) · Aging Cell · doi:10.1111/acel.13501 · Cited by 45
Metadata
- Authors
- Gridley, T.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2007-08-01
- Volume
- 134
- Issue
- 15
- Pages
- 2709-2718
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2050817855
- Cited by
- 429
- References
- 7
- FWCI
- 12.57
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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