The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

Wallingford, John B., Habas, Raymond·2005·Development

Cited by (507)

Items 301–400 of 507

  1. The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled
    Marie-Claire Kratzer, Sarah F. S. Becker, Anita Grund, Anne Margarete Merks, Jakub Harnoš, Vı́tězslav Bryja, Klaudia Giehl, Jubin Kashef, Annette Borchers · 2020 · Development
  2. The nanoscale organization of the Wnt signaling integrator Dishevelled in the vegetal cortex domain of an egg and early embryo
    John H. Henson, Bakary Samasa, Charles Bradley Shuster, Athula H. Wikramanayake · 2021 · PLoS ONE
  3. A Wnt11 and Dishevelled signaling pathway acts prior to injury to control wound polarization for the onset of planarian regeneration
    David I. Gittin, Christian P. Petersen · 2022 · Current Biology
  4. Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominant Robinow syndrome
    Sarah J. Gignac, Katja R. MacCharles, Katherine Fu, Kywana Bonaparte, Gamze Akarsu, Thalia W. Barrett, Esther M. Verheyen, Joy Marion Richman · 2023 · Disease Models & Mechanisms
  5. NKD1 down-regulation is associated with poor prognosis in breast invasive ductal carcinoma.
    Zhi‐Dong Lv, Lin Zhang, Xiang-Ping Liu, Liying Jin, Qian Dong, Funian Li, Haibo Wang, Bin Kong · 2015 · Europe PMC (PubMed Central)
  6. Formation of a “Pre-mouth Array” from the Extreme Anterior Domain Is Directed by Neural Crest and Wnt/PCP Signaling
    Laura Anne Jacox, Justin Chen, Alyssa Rothman, Hillary Lathrop-Marshall, Hazel L. Sive · 2016 · Cell Reports
  7. Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation
    Justine Ngo, Masakazu Hashimoto, Hiroshi Hamada, Anthony J. Wynshaw-Boris · 2020 · Developmental Biology
  8. Roles of Planar Cell Polarity Signaling in Maturation of Neuronal Precursor Cells in the Postnatal Mouse Olfactory Bulb
    Yuki Hirota, Masato Sawada, Yasuyuki S. Kida, Shihhui Huang, Osamu Yamada, Masanori Sakaguchi, Toshihiko Ogura, Hideyuki Okano, Kazunobu Sawamoto · 2012 · Stem Cells
  9. NEK2 plays an essential role in porcine embryonic development by maintaining mitotic division and DNA damage response via the Wnt/β‐catenin signalling pathway
    Se‐Been Jeon, Pil‐Soo Jeong, Hyo‐Gu Kang, Min Ju Kim, Ji Hyeon Yun, Kyung Seob Lim, Bong‐Seok Song, Sun‐Uk Kim, Seong‐Keun Cho, Bo‐Woong Sim · 2024 · Cell Proliferation
  10. Signaling Pathways Governing Cardiomyocyte Differentiation
    Isaiah K. Mensah, H. Gowher · 2024 · Genes
  11. Knockdown of dishevelled-1 attenuates cyclosporine A-induced apoptosis in H9c2 cardiomyoblast cells
    Yejing Zhu, Jinyu Chi, Yue Liu, Yihua Sun, Yu Fu, Xiao‐Hui Zhang, Xueliang Ding, Xinhua Yin, Dechao Zhao · 2012 · Molecular and Cellular Biochemistry
  12. The role of intracellular interactions in the collective polarization of tissues and its interplay with cellular geometry
    Shahriar Shadkhoo, Madhav Mani · 2019 · PLoS Computational Biology
  13. Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway
    Marta Vitorino, Ana Cristina Silva, José Manuel Inácio, Jose Silva Ramalho, Michal Gur, Abraham Fainsod, Herbert Steinbeißer, José António Belo · 2015 · PLoS ONE
  14. Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling
    Li Ma, Ying Wang, Craig C. Malbon, Hsien‐yu Wang · 2010 · Journal of Molecular Signaling
  15. Down‐regulation of dishevelled‐2 inhibits cell proliferation and invasion in hepatoblastoma
    Siqi Huang, Jing Chen, Ruicheng Tian, Jing Wang, Chenjie Xie, Hongxiang Gao, Yuhua Shan, Jie Hong, Zhen Zhang, Min Xu et al. · 2018 · Pediatric Blood & Cancer
  16. Colonic healing requires Wnt produced by epithelium as well as Tagln+ and Acta2+ stromal cells
    Soumyashree Das, Qiang Feng, Iyshwarya Balasubramanian, Xiang Lin, Haoran Liu, Oscar Pellón-Cárdenas, Shiyan Yu, Xiao Zhang, Yue Liu, Zhi Wei et al. · 2021 · Development
  17. Wnt signaling pathway and sclerostin in the development of atherosclerosis and vascular calcification
    Piotr Kocełak, Monika Puzianowska‐Kuźnicka, Magdalena Olszanecka‐Glinianowicz, Jerzy Tadeusz Chudek · 2023 · Advances in Clinical and Experimental Medicine
  18. Effect of Klotho protein during porcine oocyte maturation via Wnt signaling
    Eui Hyun Kim, Anukul Taweechaipaisankul, Muhammad Rosyid Ridlo, Geon A Kim, Byeong Chun Lee · 2020 · Aging
  19. Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
    Nestor Kamdem, Yvette Roske, Dmytro Kovalskyy, Maxim O. Platonov, Oleksii Balinskyi, Annika Kreuchwig, Jörn Saupe, Liang Fang, Anne Diehl, Peter Schmieder et al. · 2021 · Magnetic Resonance
  20. Novel Regulators of Planar Cell Polarity: A Genetic Analysis in Drosophila
    Ursula Weber, William J. Gault, Patricio Olguı́n, Ekaterina Serysheva, Marek Mlodzik · 2012 · Genetics
  21. Lysine Conservation and Context in TGFβ and Wnt Signaling Suggest New Targets and General Themes for Posttranslational Modification
    Charlotte E. Konikoff, Robert G. Wisotzkey, Stuart J. Newfeld · 2008 · Journal of Molecular Evolution
  22. Probing the physical nature and composition of signalsomes
    Hsien‐yu Wang, Craig C. Malbon · 2011 · Journal of Molecular Signaling
  23. Modeling polarity buildup and cell fate decision in the fly eye: insight into the connection between the PCP and Notch pathways
    Jean‐François Le Garrec, Michel Kerszberg · 2008 · Development Genes and Evolution
  24. Naked Cuticle Drosophila 1 Expression in Histologic Subtypes of Small Adenocarcinoma of the Lung
    Sangjeong Ahn, Won Hwangbo, Hyunchul Kim, Chul Hwan Kim · 2013 · Journal of Pathology and Translational Medicine
  25. Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling
    Monica Sharma, Isabel Castro‐Piedras, Fahmida Akter Rasha, Sabarish Ramachandran, Souad R. Sennoune, Kathryn L. Furr, Sharilyn Almodóvar, Vadivel Ganapathy, Matthew B. Grisham, Rakhshanda Layeequr Rahman et al. · 2021 · Oncotarget
  26. Custos controls β-catenin to regulate head development during vertebrate embryogenesis
    Yuko Komiya, Noopur Mandrekar, Akira Sato, Igor B. Dawid, Raymond Habas · 2014 · Proceedings of the National Academy of Sciences
  27. Phylogenetic and Evolutionary Analyses of the Frizzled Gene Family in Common Carp (Cyprinus carpio) Provide Insights into Gene Expansion from Whole-Genome Duplications
    Chuanju Dong, Likun Jiang, Wenzhu Peng, Jian He Xu, Shahid Mahboob, Khalid A. Al‐Ghanim, Xiaowen Sun, Peng Xu · 2015 · PLoS ONE
  28. Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin–Independent Targets by Proteomics
    Olesja Popow, João A. Paulo, Michael H. Tatham, Melanie S. Volk, Alejandro Rojas‐Fernández, Nicolas Loyer, Ian P. Newton, Jens Januschke, Kevin M. Haigis, Inke S Näthke · 2019 · Molecular Cancer Research
  29. Gradient-independent Wnt signaling instructs asymmetric neurite pruning in C. elegans
    Menghao Lu, Kota Mizumoto · 2019 · eLife
  30. Cell-autonomous, myristyl-independent activity of the Drosophila Wnt/Wingless antagonist Naked cuticle (Nkd)
    Chih‐Chiang Chan, Shu Zhang, Tolga Çağatay, Keith A. Wharton · 2007 · Developmental Biology
  31. Macrophage Dvl2 deficiency promotes NOD1-Driven pyroptosis and exacerbates inflammatory liver injury
    Xiaoye Qu, Dongwei Xu, Tao Yang, Yizhu Tian, Christopher T. King, Xiao Wang, Mingwei Sheng, Yuanbang Lin, Xiyun Bian, Changyong Li et al. · 2024 · Redox Biology
  32. A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure
    Yuko Komiya, Zhiyong Bai, Na Cai, Liping Lou, Namariq Al-Saadi, Courtney Mezzacappa, Raymond Habas, Loren Warren Runnels · 2017 · Scientific Reports
  33. Cyclin G2 upregulation impairs migration, invasion, and network formation through RNF123/Dvl2/JNK signaling in the trophoblast cell line HTR8/SVneo, a possible role in preeclampsia
    Manni Sun, Jinlan Gao, Tao Meng, Shenghuan Liu, Haiying Chen, Qi Liu, Xuesha Xing, Chenyang Zhao, Yang Luo · 2020 · The FASEB Journal
  34. Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling
    Juliusz Mieszczanek, Helen L. Strutt, Trevor J. Rutherford, David I Strutt, Mariann Bienz, Melissa V. R. Gammons · 2022 · Journal of Cell Science
  35. Dishevelled 2 regulates cancer cell proliferation and T cell mediated immunity in HER2-positive breast cancer
    Fahmida Akter Rasha, Geetha P. Boligala, Mingxiao V. Yang, Dalia Martinez‐Marin, Isabel Castro‐Piedras, Kathryn L. Furr, Annie Snitman, Sonia Y. Khan, Luis Brandi, Maribel Castro et al. · 2023 · BMC Cancer
  36. Dickkopf1 - A New Player in Modelling the Wnt Pathway
    Lykke Pedersen, Mogens H. Jensen, Sandeep Krishna · 2011 · PLoS ONE
  37. A possible founder mutation in FZD6 gene in a Turkish family with autosomal recessive nail dysplasia
    Ceren Saygı, Yasemin Alanay, Osman Uğur Sezerman, Aslı Kutlu, Nesrin Özören · 2019 · BMC Medical Genetics
  38. Cell cortex regulation by the planar cell polarity protein Prickle1
    Yunyun Huang, Rudolf Winklbauer · 2022 · The Journal of Cell Biology
  39. Wnt Signaling: A Shaggy Dogma Tale
    Elizabeth Heeg‐Truesdell, Carole LaBonne · 2006 · Current Biology
  40. Circ_0101802 Facilitates Colorectal Cancer Progression Depending on the Regulation of miR-665/DVL3 Signaling
    Jun Li, Xin-Bin Liu, Shaoting Dong, Haojie Liao, Weizhen Huang, Xia Yuan · 2022 · Biochemical Genetics
  41. The role of Wnt signaling in mesenchymal stromal cell-driven angiogenesis
    Pratheesh D. Mankuzhy, Arun Dharmarajan, Lakshmi Revathi Perumalsamy, Khan Sharun, Priyanka Samji, Rodney James Dilley · 2023 · Tissue and Cell
  42. Signaling crosstalk between TGFβ and Dishevelled/Par1b
    Anant Mamidi, Masafumi Inui, Andrea Manfrin, Sandra Soligo, Elena Enzo, Mariaceleste Aragona, Michelangelo Cordenonsi, Oliver Wessely, Sirio Dupont, Stefano Piccolo · 2012 · Cell Death and Differentiation
  43. Preliminary identification of potential PDZ-domain proteins downstream of ephrin B2 during osteoclast differentiation of RAW264.7 cells.
    Yingjie Mao, Xu Huang, Juan Zhao, Z. Gu · 2011 · International Journal of Molecular Medicine
  44. Overexpression of Dishevelled-2 contributes to proliferation and migration of human esophageal squamous cell carcinoma
    Guoren Zhou, Jinjun Ye, Lei Sun, Zhi Zhang, Jifeng Feng · 2016 · Journal of Molecular Histology
  45. Microarray Analysis of Gene Expression Profiles of Schistosoma japonicum Derived from Less-Susceptible Host Water Buffalo and Susceptible Host Goat
    Jianmei Yang, Yang Hong, Chunxiu Yuan, Zhiqiang Fu, Yaojun Shi, Min Zhang, Liuhong Shen, Yanhui Han, Chuangang Zhu, Hao Li et al. · 2013 · PLoS ONE
  46. Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled
    Ho‐Jin Lee, Nick X. Wang, De‐Li Shi, Jie Zheng · 2009 · Angewandte Chemie
  47. Wnt Signaling Induces Asymmetric Dynamics in the Actomyosin Cortex of the C. elegans Endomesodermal Precursor Cell
    Francesca Caroti, Wim Thiels, Michiel Vanslambrouck, Rob Jelier · 2021 · Frontiers in Cell and Developmental Biology
  48. Dvl proteins regulate SMAD1, AHR, mTOR, BRD7 protein expression while differentially regulating canonical and non-canonical Wnt signaling pathways in CML cell lines
    Ceyda Çalışkan, Zeynep Yüce, Hakki Ogün Sercan · 2022 · Gene
  49. Cryo-EM structure and oligomerization of the human planar cell polarity core protein Vangl1
    Fan Zhang, Shaobai Li, Hao Wu, Shanshuang Chen · 2025 · Nature Communications
  50. Inhibiting the Wnt Signaling Pathway with Small Molecules
    Ho‐Jin Lee, Xinxin Zhang, Jie Zheng · 2010 · Springer eBooks
  51. Canonical Wnt Signaling: An Unexpected New Player
    Raymond Habas · 2006 · Developmental Cell
  52. Combinatorial Wnt signaling landscape during brachiopod anteroposterior patterning
    Bruno C. Vellutini, José María Martín-Durán, Aina Børve, Andreas Hejnol · 2024 · BMC Biology
  53. An overview of the effect of the Wnt signaling pathway in lung cancer
    Eda Nur Avşar, İdi̇l Çeti̇n, Mehmet Topçul · 2022 · Cellular and Molecular Biology
  54. Dishevelled Binds the Discs Large ‘Hook’ Domain to Activate GukHolder-Dependent Spindle Positioning in Drosophila
    Joshua D Garcia, Evan B. Dewey, Christopher A. Johnston · 2014 · PLoS ONE
  55. Wg signaling in Drosophila heart development as a pioneering model
    Xiushan Wu · 2010 · Journal of genetics and genomics/Journal of Genetics and Genomics
  56. PLD1 regulates Xenopus convergent extension movements by mediating Frizzled7 endocytosis for Wnt/PCP signal activation
    Lee, Hyeyoon, Lee, Seung Joon, Kim, Gun-Hwa, Yeo, Inchul, Han, Jin-Kwan · 2016 · Developmental Biology
  57. Identification and Validation of Prognostic Markers for Lung Squamous Cell Carcinoma Associated with Chronic Obstructive Pulmonary Disease
    Zheng Li, Dan Xu, Jing Jing, Jing Wang, Min Hai Jiang, Fengsen Li · 2022 · Journal of Oncology
  58. Wnt/β-catenin signaling within multiple cell types dependent upon kramer regulates Drosophila intestinal stem cell proliferation
    Hongyan Sun, Adnan Shami Shah, Din-Chi Chiu, Alessandro Bonfini, Nicolas S. Buchon, Jeremy M. Baskin · 2024 · iScience
  59. Dishevelled: An emerging therapeutic oncogene in human cancers.
    S. Alshahrani, N. Rakhimov, Arti Rana, H. Alsaab, A. Hjazi, Mohaned Adile, M. Abosaooda, Adeeb Abdulally Abdulhussien alazbjee, Ali H. Alsalamy, Reza Mahmoudi · 2023 · Pathology, Research and Practice
  60. Genome-wide network analysis of Wnt signaling in three pediatric cancers
    Ju Bao, Ho‐Jin Lee, Jie Zheng · 2013 · Scientific Reports
  61. Acquisition of cell polarity during cell cycle and oral replacement in Tetrahymena
    Janina Kaczanowska, Szymon Kaczanowski, Mauryla Kiersnowska, Hanna Fabczak, Karolina Tułodziecka, Andrzej Kaczanowski · 2008 · The International Journal of Developmental Biology
  62. Wnt/Planar Cell Polarity Signaling in the Regulation of Convergent Extension Movements During Xenopus Gastrulation
    Gun‐Hwa Kim, Edmond Changkyun Park, Jin‐Kwan Han · 2011 · Methods in molecular biology
  63. Cell Signaling: Moving to a Wnt-Rap
    Habas, Raymond, He, Xi · 2007 · Current Biology
  64. Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells
    Philip Barron Abitua, Tae Joo Park, Brian J. Mitchell, Chris R. Kintner, John B. Wallingford · 2009 · Developmental Biology
  65. The ubiquitin-proteasome system and chromosome 17 in cerebellar granule cells and medulloblastoma subgroups
    Jerry P. Vriend, Hassan Marzban · 2016 · Cellular and Molecular Life Sciences
  66. Tissue-specific expression of aryl hydrocarbon receptor and putative developmental regulatory modules in Baltic salmon yolk-sac fry
    Kristiina A. M. Vuori, Eija Nordlund, Jenny Kallio, Tapio Salakoski, Mikko Nikinmaa · 2008 · Aquatic Toxicology
  67. Specification and patterning of the animal‐vegetal axis in sea urchins by the canonical Wnt signaling pathway
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  68. Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation
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  69. Wnt Signaling in Cardiac Disease
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  72. WNTers in La Jolla
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  73. Extrinsic Wnt signalling controls the polarity component aPKC
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  74. Tumorhead distribution to cytoplasmic membrane of neural plate cells is positively regulated by Xenopus p21-activated kinase 1 (X-PAK1)
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  75. The Wnt‐signaling pathways in mammalian patterning and morphogenesis
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  76. Protein Kinases Involved in the Regulation of Wnt/β-catenin Signaling
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  77. Wnt/β-catenin signaling regulates pathogenesis of human middle ear cholesteatoma.
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  78. Cortical Cyclin A controls spindle orientation during asymmetric cell divisions in Drosophila
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  79. Silencing of Wwox Increases Nuclear Import of Dvl proteins in Head and Neck Cancer
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  80. Dishevelled‑2 modulates osteogenic differentiation of human synovial fibroblasts in osteoarthritis
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  81. Fundamental origins of neural tube defects with a basis in genetics and nutrition
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  82. Dishevelled localization and function are differentially regulated by structurally distinct sterols
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  83. Rare missense variants in DVL1, one of the human counterparts of the Drosophila dishevelled gene, do not confer increased risk for neural tube defects
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  84. Cilia—Where Two Wnts Collide
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  86. Dishevelled localization and function are differentially regulated by structurally distinct sterols
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  87. Dishevelled-1 regulates global transcriptomic changes and associates with ETS1 transcription factor
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  89. Wnt Signaling Drives Ectopic Gene Expression and Larval Arrest in the Absence of theCaenorhabditis elegansDREAM Repressor Complex
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  90. Dishevelled Segment Polarity Protein 3: A Novel Prognosis-related Marker in Pan-driver-gene-negative Lung Adenocarcinoma
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  91. Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF
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  93. Principles of Cell Signaling
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  96. The Wnt co-receptor Arrow-LRP5/6 is required for planar cell polarity establishment in Drosophila
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  97. Non-Canonical Wnt Pathway Expression in the Developing Mouse and Human Retina
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  100. Modulation of Dishevelled and Vangl2 by All-trans-retinoic Acid in the Developing Mouse Central Nervous System and its Relationship to Teratogenesis
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